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Unraveling the Pathways: A Meta-Analysis Exploring the Biopsychosocial Mechanisms Linking Psychosomatic Symptoms and Systemic Lupus Erythematosus Ridho Pratama; Arina Widya Murni
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1201

Abstract

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by a complex interplay of biological, psychological, and social factors. Psychosomatic symptoms, such as depression, anxiety, and stress, are common in individuals with SLE and can significantly impact disease activity and overall well-being. This meta-analysis aims to explore the biopsychosocial mechanisms linking psychosomatic symptoms and SLE. Methods: A systematic search of PubMed, Embase, PsycINFO, and Web of Science databases was conducted from January 2013 to December 2024. Studies examining the relationship between psychosomatic symptoms and SLE were included. Data were extracted and analyzed using random-effects models to calculate pooled effect sizes. Results: Six studies met the inclusion criteria. The meta-analysis revealed a significant association between psychosomatic symptoms (depression, anxiety, and stress) and SLE disease activity (pooled effect size: r = 0.42, 95% CI: 0.31-0.53, p < 0.001). Furthermore, dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, pro-inflammatory cytokine activity, and impaired coping mechanisms emerged as key biopsychosocial pathways linking these factors. Conclusion: This meta-analysis highlights the significant impact of psychosomatic symptoms on SLE and identifies potential underlying mechanisms. These findings underscore the need for integrated biopsychosocial interventions in SLE management, targeting both physical and psychological well-being to improve patient outcomes.
Hubungan antara Stres Akademik dengan Kecenderungan Gejala Somatisasi pada Mahasiswa Program Studi Kedokteran Tingkat Akhir Fakultas Kedokteran Universitas Andalas Angkatan 2015 Irlaks, Viton Surya; Murni, Arina Widya; Liza, Rini Gusya
Jurnal Kesehatan Andalas Vol. 9 No. 3 (2020): Online September 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1366

Abstract

 Stres akademik merupakan suatu keadaan emosional yang paling umum dialami oleh mahasiswa selama masa studi. Stres yang tidak dikontrol dengan baik dapat mempengaruhi terjadinya gejala somatisasi. Tujuan: Menentukan hubungan antara stres akademik dengan kecenderungan gejala somatisasi pada mahasiswa program studi kedokteran tingkat akhir Fakultas Kedokteran Universitas Andalas angkatan 2015. Metode: Penelitian ini adalah analitik dengan desain cross sectional. Responden penelitian adalah 100 orang mahasiswa program studi kedokteran tingkat akhir Fakultas Kedokteran Universitas Andalas Angkatan 2015. Pengambilan sampel dilakukan dengan teknik random sampling berdasarkan kriteria inklusi dan ekslusi. Instrumen penelitian ini menggunakan kuesioner Medical Student Stress Questionnaire (MSSQ) dan The Somatic Symptom Scale - 8 (SSS-8). Data dianalisis menggunakan uji bivariat Fisher’s exact. Hasil: Penelitian menunjukkan 43 orang (43%) adalah laki - laki dan 57 orang (57%) adalah perempuan. Usia terbanyak adalah 21 tahun (74%) dan paling sedikit 20 tahun (9%). Tingkat stres akademik 56 orang sedang (56%) dan 4 orang sangat berat (4%). Tingkat kecenderungan gejala somatisasi 26 orang sedang (26%) dan 11 orang sangat ringan (11%). Sebanyak 24 orang yang mengalami stres akademik memiliki kecenderungan gejala somatisasi sedang (27,9%). Analisis bivariat menunjukkan nilai p = 0,000 (p < 0,05). Simpulan: Terdapat hubungan yang bermakna antara stres akademik dengan kecenderungan gejala somatisasi pada mahasiswa program studi kedokteran tingkat akhir Fakultas Kedokteran Universitas Andalas angkatan 2015.Kata kunci: stres akademik, gejala somatisasi, mahasiswa tingkat akhir
Hubungan Tingkat Keparahan Pasien COVID-19 dengan Distres Psikologis Pada Periode 1 Maret 2020 sampai 31 Desember 2021 di Rumah Sakit Universitas Andalas Liandhu Hakim, Sonya; Widya Murni, Arina; Yulistini, Yulistini; Gusya Liza, Rini; Ermayanti, Sabrina; Ashal, Taufik
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 1 (2025): Maret 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i1.1102

Abstract

Latar Belakang: Wabah COVID-19 (Coronavirus Disease 19) menimbulkan dampak jangka panjang terhadap kesehatan mental. Studi menilai kesehatan mental akibat keparahan COVID-19 masih belum dijadikan sebagai prioritas utama penatalaksanaan COVID-19. Objektif: Penelitian ini bertujuan mengetahui hubungan antara tingkat keparahan COVID-19 dengan stres pasien COVID-19. Metode: Penelitian potong lintang ini dilakukan pada periode 1 Maret 2020 Sampai 31 Desember 2021 di Rumah Sakit Universitas Andalas. Penelitian menggunakan data rekam medis pasien terkonfirmasi COVID-19 yang telah dinilai tingkat stres menggunakan DASS-21 (Depression, Anxiety, Stress Scale 21). Sebanyak 55 responden di ambil dengan teknik pengambilan sampel acak sederhana yang memenuhi kriteria inklusi dan ekslusi. Hasil: Lebih dari setengah pasien COVID-19 (54,5%) memiliki tingkat keparahan penyakit sedang dan 56,3% mengalami tingkat stres sedang. Uji Chi–square menunjukkan hasil yang signifikan dengan nilai p sebesar 0,000. Kesimpulan: Terdapat hubungan yang signifikan secara statistik antara tingkat keparahan COVID-19 dengan tingkat stres pada pasien terkonfirmasi COVID-19. Oleh sebab itu, pendekatan psikologis diperlukan untuk tata laksana pasien COVID-19 untuk mengurangi pengaruh psikis terhadap keparahan penyakit.  
Hubungan Koping dengan Prestasi Akademik pada Mahasiswa Perantau Fakultas Kedokteran Universitas Andalas Wijaya, Harwin; Yanis, Amel; Yanni, Mefri; Murni, Arina Widya; Fasrini, Ulya Uti; Abdiana, Abdiana
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.1206

Abstract

Latar Belakang: Koping merupakan suatu upaya kognitif atau perilaku untuk menghadapi tuntutan dari luar maupun dari dalam diri. Mahasiswa perantau sebagai individu yang pergi ke daerah lain dan dituntut untuk mampu menyesuaikan diri pada lingkungan baru, bila upaya penyesuaian tidak berjalan dengan baik dapat memunculkan stres atau bahkan beban mental yang dapat berdampak pada kemampuan mencapai prestasi akademik yang optimal. Dibutuhkan suatu mekanisme untuk menghadapi masalah tersebut, salah satunya adalah koping. Objektif: Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara kemampuan koping dengan prestasi akademik pada mahasiswa perantau Program Studi Kedokteran Fakultas Kedokteran Universitas Andalas angkatan 2019. Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional yang menggunakan total sampling dengan didapatkan jumlah sampel sebanyak 96 orang yang merupakan mahasiswa perantau Program Studi Kedokteran Fakultas Kedokteran Universitas Andalas. Pengumpulan data responden diperoleh dari kuesioner dan data dianalisis menggunakan uji Fisher’s Exact Test. Hasil: Hasil analisis univariat menunjukkan mayoritas responden memiliki kemampuan koping adaptif (93,8%) dan minoritas responden memiliki kemampuan koping maladaptive. Kategori cukup memuaskan, memuaskan, dan sangat memuaskan (53,1%) merupakan kategori indeks prestasi yang terbanyak diperoleh responden dan minoritas responden memiliki kategori dengan pujian (46,9%). Kesimpulan: Tidak terdapat hubungan yang signifikan antara kemampuan koping dengan prestasi akademik (p=1).
PEMERIKSAAN DAN PENGOBATAN MATA DAN KULIT PADA KELOMPOK LANSIA DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Rina Gustia; Hendriati Hendriati; Zelly Dia Rofinda; Yulistini Yulistini; Afriwardi Afriwardi; Elmatris Sy
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 2 No. 1 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v2i1.97

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Health services for the elderly need to get special attention, because they are vulnerable for suffering from disease and tend to experience multi-pathology. Some of the health problems of the elderly in Kenagarian Sumaniak had been identified in community service activities before. Aim: The activity aims is to conduct examination and treatment of eye and skin disorders, as also to conduct counseling on the elderly. Methods: The activity is ayes and skin examination and treatment for elderly people in Kenagarian Sumaniak. Furthermore, counseling was also given regarding physical fitness and maintenance of skin health in the elderly. Results: The event was attended by 70 people aged 52-82 years, 28 men and 52 women. The results of the examination found 64 people suffering from eye disorders with diagnoses were dry eyes 24person, immature cataract 16 person and pterygium14 person. Around 52 people suffering from skin disorders with diagnoses were dermatitis 28 person such as dermatitis allergy, numularis, intertriginosa, sebaroid, and chronic). Conclusions: Health problems in the eyes and skin of the elderly identified are mostly overcome with the medicines provided. Some of them are recommended to go to primary health care to get further health services.
PEMERIKSAAN BUTA WARNA, GOLONGAN DARAH DAN KADAR HEMOGLOBIN PADA ANAK USIA SEKOLAH DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Zelly Dia Rofinda; Hendriati Hendriati; Julizar Julizar; Rahmat Syawqi; Husnil Wardiyah
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 3 No. 2 (2020)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v3i2.199

Abstract

The growth and development of children disturbance is a health problem that often is found in the community. Anemia and colour blindness are also health conditions that can affect the quality of growth and development of children, which parents rarely realize. The blood type of children is seldom defined in early ages by the parents. This activity aims to conduct health counselling, the examination of colour blindness, blood type, and hemoglobin levels in school-age children in Sumanik village. Methods: Activities were health education on how to wash hands properly and be aware of internet content. The activities were continued by a health examination, such as examining colour blindness, hemoglobin levels, and blood type. Testing of blood type on 76 children, two of 79 children has partial colour blindness. We found From 28 children (36.4%) having anemia, with hemoglobin levels 9.2-11.9 gr / dL, and one child has a blood type B rhesus (-). From this activity, it can be concluded that the low level of knowledge of school-age children in Kenagarian Sumaniak about how to wash hands properly and correctly, even children do not know the adverse effects associated with adult content on the internet. In addition, it appears that children with anemia are still relatively high. For this reason, continuous health promotion is needed. For disorders that can not be overcome at the time of activity, it is recommended to get treatment to the nearest health care centre.
EDUKASI COVID-19 DAN VAKSINASI BAGI MASYARAKAT DI KAMPUNG BATU BUSUAK KECAMATAN PAUH KOTA PADANG Saptino Miro; Roza Kurniati; Dwitya Elvira; Arina Widya Murni; Raveinal Raveinal; Alexander Kam
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 5 No. 1 (2022)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v5i1.398

Abstract

Infectious diseases are still a major health issue that requires serious treatment. The covid-19 is now one of the significant infectious diseases worldwide marked by rapid contagion and global spread. The world health organization (who) has defined covid-19 as a global pandemic and the government has set public health emergencies in Indonesia, obliging countermeasures. The covid-19 countermeasures should continue massively with several strategies. In addition to promotive strategies and the application of health protocols, another effective strategy is needed to break off the chain of disease transmission through vaccination efforts. The purpose of the activity is to do the education about covid-19 and the covid-19 vaccination of the people in Kampung Batu Busuak, Kelurahan Limau Manis, Kecamatan Pauh, Padang. The implementation of this activity includes the counseling of covid-19 and the covid-19 vaccination on Saturday, November 13th, 2021. Before counseling, the Questionnaire was issued to assess a public knowledge level on covid-19 and a covid-19 vaccination. From a questionnaire on covid-19 and covid-19 vaccination, the total of people who have already been vaccinated twice is 22 people and 4 with the covid-19 vaccine once. Therefore, still needed counseling about covid-19 and covid-19 vaccination to enhance awareness of the society towards the importance of covid-19 vaccination.
Faktor Risiko Stres Emosional pada Mahasiswa Kedokteran tahun Pertama Universitas Andalas di Masa Pandemi COVID-19 Mar’atul Fadhilah; Arina Widya Murni; Amel Yanis
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 14, No 3 (2023): Juli - September 2023
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf14320

Abstract

Emotional stress is a psychological reaction due to stressors that can be detrimental, whether physical, mental or emotional stimuli that tend to disrupt the function of the organism which can activate the organism's flight or fight reaction. The COVID-19 pandemic situation is a new stressor for first year medical students because they immediately face the transition period of learning to online so they have to adapt to the new learning system. The aim of the research was to determine the risk factors that trigger emotional disorders in first year medical students at Andalas University class of 2020 during the COVID-19 pandemic. This study implemented a cross-sectional design. The subjects of this research were first year medical students at Andalas University. The measurement instruments used were the DASS-42 and the Holmes and Rahe Stress Scale for Youth. The total number of medical students who experienced stress from a total sample of 225 was 74 people (32.9%). The risk factor for student stress in this study was the learning process (69 people). Factors that aggravate academic stress were the death of family members/other family members/partners/close friends. The factor that relieves academic stress was vacation. The p value for the analysis of the relationship between stress levels and risk factors was >0.05 (not significant). It was concluded that the risk factor for emotional stress for medical students class of 2020 at Andalas University during the COVID-19 pandemic was the academic atmosphere.Keywords: medical students; first year; risk factors; stress ABSTRAK Stres emosional adalah reaksi psikologis akibat stressor yang dapat merugikan, baik stimulus fisik, mental, ataupun emosional yang cenderung mengganggu fungsi organisme yang dapat mengaktifkan reaksi  flight or fight oleh organisme tersebut. Situasi pandemi COVID-19 merupakan  stressor baru bagi mahasiswa kedokteran tahun pertama karena langsung menghadapi masa transisi pembelajaran menjadi daring sehingga mereka harus beradaptasi dengan sistem pembelajaran baru. Tujuan penelitian adalah untuk mengetahui faktor risiko pencetus timbulnya gangguan emosi mahasiswa kedokteran Universitas Andalas tahun pertama angkatan 2020 di masa pandemi COVID-19. Penelitian ini menerapkan desain cross-sectional. Subjek penelitian ini ialah mahasiswa kedokteran tahun pertama Universitas Andalas. Instrumen pengukuran yang digunakan adalah DASS-42 dan Holmes and Rahe Stress Scale for Youth. Total mahasiswa kedokteran yang mengalami stres dari total sampel 225 adalah sebanyak 74 orang (32,9%). Faktor risiko stres mahasiswa pada penelitian ini ialah proses pembelajaran (69 orang). Faktor yang memperberat stres akademik tersebut ialah kematian anggota keluarga/anggota keluarga lain/pasangan/teman dekat. Faktor yang meringankan stres akademik ialah liburan. Nilai p unuk analisis hubungan antara tingkat stres dengan faktor risikonya adalah >0,05 (tidak signifikan). Disimpulkan bahwa faktor risiko stres emosional mahasiswa kedokteran angkatan 2020 Universitas Andalas di masa pandemi COVID-19 ialah faktor suasana akademik.                         Kata kunci: mahasiswa kedokteran; tahun pertama; faktor risiko; stres
The Nexus of Neuroinflammation and Psychopathology in Neuropsychiatric Systemic Lupus Erythematosus (NPSLE): A Meta-Analysis of Anti-NMDAR, Anti-Ribosomal P Antibodies, and Psychosomatic Manifestations (Depression, Anxiety, Cognitive Dysfunction) Anggi Setiawan; Arina Widya Murni
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 8 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i8.1357

Abstract

Background: Neuropsychiatric systemic lupus erythematosus (NPSLE) significantly impacts patients through diverse neurological and psychiatric symptoms, including prevalent psychosomatic manifestations like depression, anxiety, and cognitive dysfunction. Specific autoantibodies, such as anti-N-methyl-D-aspartate receptor (anti-NMDAR) and anti-ribosomal P protein (anti-RP) antibodies, are implicated in its complex neuroinflammatory pathogenesis. This meta-analysis aimed to quantitatively assess the association between these autoantibodies and these key psychosomatic outcomes in NPSLE. Methods: A systematic literature search of PubMed, EMBASE, Scopus, and PsycINFO (2014-2024) identified observational studies reporting on anti-NMDAR or anti-RP antibodies and depression, anxiety, or cognitive dysfunction in adult NPSLE patients. Data from six eligible studies (850 patients) were extracted and quality was assessed. Pooled odds ratios (ORs) or standardized mean differences (SMDs) were calculated using a random-effects model, with heterogeneity and publication bias evaluated. Results: Anti-NMDAR antibody positivity was significantly associated with increased odds of cognitive dysfunction (OR = 2.85, 95% CI = 1.90-4.28). Anti-RP antibody positivity was significantly linked to increased odds of depression (OR = 3.20, 95% CI = 2.15-4.76) and anxiety (OR = 2.50, 95% CI = 1.65-3.78). Moderate heterogeneity was noted for some analyses. Conclusion: This meta-analysis highlights distinct associations: anti-NMDAR antibodies with cognitive dysfunction, and anti-RP antibodies with depression and anxiety in NPSLE. These findings underscore the potential role of these autoantibodies in specific psychosomatic symptom clusters, guiding further research and clinical consideration in NPSLE management.
Opioid Rotation vs. Dose Titration in Refractory Cancer Pain: A Meta-Analysis of Efficacy and Adverse Events Arina Widya Murni; Dian Arfan As Bahri; Widya Deli Satuti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 9 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i9.1375

Abstract

Background: The management of refractory cancer pain represents a formidable clinical challenge at the intersection of oncology and palliative medicine. When patients with advanced malignancy fail to achieve adequate analgesia or develop intolerable adverse effects from their opioid regimen, clinicians are faced with a crucial decision: to escalate the dose of the current opioid (dose titration) or to switch to a different opioid agent (opioid rotation). The optimal strategy remains a subject of intense debate and variable practice. This meta-analysis was conducted to rigorously compare the efficacy and safety of these two common interventions. Methods: A systematic and comprehensive search was performed in the PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases for randomized controlled trials (RCTs) published between January 2015 and December 2024. We included studies that directly compared opioid rotation with dose titration in adult palliative care patients diagnosed with refractory cancer pain. The primary efficacy outcome was the change in pain intensity, analyzed using the Standardized Mean Difference (SMD) to accommodate pain scales such as the Numerical Rating Scale (NRS) and Visual Analogue Scale (VAS). Primary safety outcomes were the incidence of severe neurotoxicity and severe constipation. Data were pooled using a random-effects model, and results were expressed as SMD for the continuous pain outcome and Risk Ratio (RR) for dichotomous adverse events, with corresponding 95% confidence intervals (CI). Results: Seven RCTs, encompassing a total of 962 patients, met the stringent inclusion criteria. The pooled analysis revealed that the strategy of opioid rotation resulted in a statistically significant and clinically substantial greater reduction in pain intensity compared to continued dose titration (SMD -0.65, 95% CI [-0.88, -0.42], p<0.00001; I²=81%). Furthermore, the risk of developing severe neurotoxicity, including delirium and myoclonus, was significantly lower in the rotation group (RR 0.62, 95% CI [0.45, 0.85], p=0.003; I²=18%). There was no statistically significant difference in the incidence of severe constipation between the two intervention groups (RR 0.90, 95% CI [0.71, 1.14], p=0.38; I²=24%). Conclusion: In patients with refractory cancer pain, the strategy of opioid rotation provided superior analgesia and was associated with a markedly lower risk of severe neurotoxicity when compared to the continued dose titration of the same opioid. These findings provide strong, high-level evidence to support the use of opioid rotation as a primary and proactive strategy for managing uncontrolled pain or dose-limiting side effects in the palliative care population.
Co-Authors Abdiana Abdiana, Abdiana Adnil E Nurdin, Adnil E Adnil Edwin Nurdin Afriwardi Afriwardi Agustin, Nia Mitra Ahmad, Armen Aisyah Elliyanti Akmal M. Hanif Alexander Kam Alexander Kam Alfitri Alfitri Amel Yanis Andriyan, Aric Frendi Anggi Setiawan Ardian Riza Ariani, Novita Ashal, Taufik Asir, Taufik Rizkian Athiutama, Ari Beni Indra, Beni Bobbi Hemriyantton Dea Rika Putri Purba Dedy Almasdy Deka Viotra Delmi Sulastri Desmawati Desmawati Dewi Eka Putri Dia Rofinda, Zelly Dia Dian Arfan As Bahri Dian Pertiwi Dian Pertiwi Diny Amenike Dita Nelvita Sari Dwitya Elvira, Dwitya Edison Edison Eldi Sauma Elizabeth Bahar Elmatris Sy Emil Huriani Emil Prasetyo Muhammad Ennesta Asri Erlina Rustam Ermayanti, Sabrina Eryati Darwin Esi Afriyanti Eti Yerizel Etriyel Myh Fadella, Annesa Fadhlurrahman Wide Putra Fadrian, Fadrian Faheri, Eifel Gemini, Savitri Gina Matahati Gina Sonia Gusya Liza, Rini Gusyaliza, Rini Hanum, Fathiya Juwita Harahap, Hana Yulia Rahmi Harun Harnavi Hasmiwati Havizur Rahman Havizur Rahman Helmi Arifin Hendra Permana Hendriati, Hendriati Husnil Wardiyah Indah Paradifa Sari Irlaks, Viton Surya Irwadi Irwadi Isnindiah Koerniati Julizar Julizar Julizar Julizar Kurniawan, Eka Liandhu Hakim, Sonya Lily Yanti Mardi, Tris Mar’atul Fadhilah Masrul Mona Rahmi Rulianti1 Muhamad Diva Caesar Muhammad Husnul Ikhsan Najirman, Najirman Nasrul Zubir Nur Indrawati Lipoeto Nurhajjah, Sitti Oktarina, Elvi Poedjijo, Yanuar Surya Saputra Priyono, Drajad Puja Agung Antonius Putra Rio, Yugo Berri Rafli, Rhandyka Rahman, Havizur Rahmat Syawqi Rahmat Syawqi Rahmatina B Herman Rahmi, Wahida Rahmy Nurdin RAVEINAL RAVEINAL Raveinal Raveinal Resti Yuliani Restu Susanti Ridho Berlianto Ridho Pratama Rihaliza Rihaliza Rika Fatmadona Rika Susanti Rina Gustia Rini Gusya Liza, Rini Gusya Rismawati Yaswir Rita Hamdani Rizanda Machmud Rose Dinda Martini Roza Kurniati Roza Kurniati Roza Mulyana Salma Nabilaputri Nadiaskara Saptino Miro Simajuntak, Rohayat Bilmahdi Siti Nurhajjah Situmorang, Risna Sari Sri Wahyuni Tasman Tasman Tasman Tasman Tasman Tris Mardi Ulya Uti Fasrini Vania Aresti Yendrial Vilza Maharani Syahnel Vina Muspita Viton Surya Irlaks Vokal Furkano WAHYUDI Wahyudi, Adefri Wardhy Arief Hidayat Widya Deli Satuti Wijaya, Harwin Winda Resvi Juliana Yanni, Mefri Yevri Zulfiqar Yoerizta Ratu, An Nissa’ Yovanda, Ryandri Yugo Berri Putra Rio Yui Muya Yulistini, Yulistini Yuriko Andre Yutika Jasvita Zelly Dia Rofinda