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All Journal Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas The Indonesian Biomedical Journal Jurnal Ilmiah Universitas Batanghari Jambi Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Jurnal Farmasi Higea Poltekita : Jurnal Ilmu Kesehatan Contagion: Scientific Periodical Journal of Public Health and Coastal Health Tatar Pasundan : Jurnal Diklat Keagamaan Journal of Telenursing (JOTING) Science Midwifery JPK: Jurnal Proteksi Kesehatan Indonesian Journal of Global Health research Jurnal Dunia Gizi Jurnal Menara Medika Poltekita: Jurnal Pengabdian Masyarakat Narra J FORTE JOURNAL Basic and Applied Nursing Research Journal Jurnal Ilmu Kesehatan Indonesia (JIKSI) Andalas Dental Journal SENTRI: Jurnal Riset Ilmiah Tatar Pasundan: Jurnal Diklat Keagamaan Jurnal Riset Ilmiah
Afriwardi Afriwardi
Bagian Fisiologi, Fakultas Kedokteran, Universitas Andalas
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Journal : Indonesian Journal of Global Health research

 1 
Relationship Between Dried Amnion Sheet and Dry Powdered Amnion with Changes in Wound Area in Acute Wounds Ferdinand, Ferdinand; Afriwardi, Afriwardi; Perdanakusuma, David Sontani; Ali, Hirowati
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6906

Abstract

Dried sheet amnion has long been used as a wound treatment that provides better results than standard general care. In addition to dried amnion sheet, dry powdered amnion preparations have begun to be used for wound care. This study aims to evaluate the effectiveness of dry powdered amnion compared to dried amnion sheets in wound healing, and to compare both treatments with standard acute wound care. Sixty-three healthy Wistar rats were randomly divided into three groups: dried amnion sheet treatment group, dry powdered amnion treatment group, and standard wet wound care control group. The research procedure began with the administration of anesthesia using penthotal at a dose of 10mg/kgBW intramuscularly. The backs of the rats were shaved and a 2x1cm wound was designed using a GOAL razor blade after disinfection with 10% betadine solution and 1:30 savlon. Wounds were made on the backs of the rats, and treatments were given according to the group. The wound area was evaluated at time points 6 hours after treatment, day 2 and day 5. Statistical analysis was performed to compare the effectiveness of the treatments. Both treatments with dry powdered amnion and dried amnion sheets significantly reduced the wound area compared to the control group. However, treatment with dried amnion sheets showed higher efficacy in reducing wound area compared to treatment with dry powdered amnion. Statistical analysis confirmed significant differences in wound area reduction between groups. Dry powdered amnion and dried amnion sheets were effective in reducing wound area compared to standard wet wound care. Treatment with dried amnion sheets showed greater efficacy than treatment with dry powdered amnion.
Co-Authors Adang Bachtiar Adrul Fauzan Afrinita Eka Fitri Ahmad Wira Aisyah Elliyanti Akdri Andi Alya Misdhal Rini Amanda Besta Rizaldy Antoni, Adi Arina Widya Murni Arni Amir Asril Zahari Asterina Asterina Aulia Fash Farabi Ayu Anissa Bahri Azis, Putri Nurul Syafirah Bestari J. Budiman Biomechy Oktomalioputri, Biomechy Bobby Indra Utama Brian Sri Prahastuti Citra Manela Daan Khambri Dara, Widia Dedi Sutia Dedy Kurnia Delmi Sulastri Delmi Sulastri Desmawati Desmawati Desrida Desrida Detty Iryani Dezi Ilham Dhiaulhaq, Zalva Indira Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Didin Kustantiningtyastuti Dina Arfiani Rusjdi Dwitya Elvira, Dwitya Edison Edison Efendi, Nursyirwan Efrida Efrida Eka Nofita Eldi Sauma Elizabeth Bahar Elmatris Elmatris Elmatris Sy Elsa Noftalina Endang Mutiwara Endrinaldi Eny Yantri Erasta, Junira Erin Desweni Ermayanti, Sabrina Eryati Darwin Eti Yerizel Eva Decroli Eva Decroli Fadhilati Sabrina Fadilla, Utami Budhi Febby Herayono Ferdinand Ferdinand, Ferdinand Fika Anggraini Fika Anggraini Fika Tri Anggraini Ghozi Natul Isral Gumilar, Erry Gusriyani, Sri Gusti Revilla Hardisman Harie Satria ES Haslan Muhaimin Lubis Hasmiwati Hendriati, Hendriati Hidayati Hidayati Hirowati Ali Hirowati Ali, Hirowati Hudila Rifa Karmia Husna Yetti Husnil Kadri Ilhami, Yose Ramda Ilmiawati, Ilmiawati Ilvira Ulpa Ismail Intan Nurwida Hayati Yasrial Iria Ningsih Busri Jamsari Jamsari Johanes C. Mose Joserizal Serudji Julizar Julizar Julizar Julizar Julizar Julizar Lastri Daniati Lili Irawati Lili Irawati Masrul Syafri Mayetti Mayetti Meidiza Ariandiny Mety Dwi Putri Eszy Miftah Irrahmah Miftah Irrahmah Miftah Irramah Miftahul Jannah Milfa Sari Muzamil Mohamad Reza Mudjiran Muhammad Amirul Ihsan Saputra Musrizal Adli Mutia Lailani Najirman Najirman Nega Olavia Nelson, Nelvianti Nova Relida Samosir Noverika Windasari Nur Afrainin Syah Nur Indrawati Lipoeto Nur Indrawaty Lipoeto Nurfazlina Nurfazlina Nurhajjah, Sitti Nuzulia Irawati Perdanakusuma, David Sontani Prayitno, Irwan Prima Astuti Handayani Pudia M. Indika Putra, Andani E. Putri Anindita Putri Nurul Syafirah Azis Putri, Biomechy Oktomalio Rahmad Syawqi Rahmad Syawqi Raisa Hussein Rama Feriska Putra Rani Ashari Reny Jayusfani Restu Susanti Reza Ekatama Rajasa Rika Susanti Rina Gustia Rini Gusya Liza Rini Gusya Liza, Rini Gusya Rita, Rauza S. Ritonga, Sukhri Herianto Rizki Hidayah Rizqa Fiorendita Hadi Rose Dinda Martini Rozi Sastra Purna Rurin Ardiyanti Russilawati, Russilawati Sabrina Hayati Safitri, Yunni Salman Umar Salman Umar Salwi, Hanifah Emilia Selfi Renita Rusjdi Setia Budi Zein Shafira Widia Putri Siska Andriani Rukmana Siti Coryniken Siti Nurhajjah Sukri Rahman susi susi Syawqi, Rahmat Taufik Hidayat Taufik Hidayat Tiffany Atia Aristi Triananda, Claudia Vaulinne Basyir Vaulinne Basyir Vitresia, Havriza Wahyu Margi Sidoretno Wenny Rahmalia Rezki Wira Ditya Wirsma Arif Harahap Yessy Susanty Sabri Yolanda Syahdia Yose Ramda Ilhami Yose Ramda Ilhsmi Yufri Aldi Yuharika Pratiwi Yulistini, Yulistini Yuniar Lestari Yusnawati Yusnawati Yusrawati Yusrawati Yusri Dianne Jurnalis Zelly Dia Rofinda