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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Indonesian Journal of Urology MEDISAINS Indonesian Journal of Obstetrics & Gynecology Science Jurnal Teknik Informatika UNIKA Santo Thomas Majalah Patologi Indonesia Indonesian Journal of Global Health research Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) MEDIC MEdical Dedication Medical Scope Journal (MSJ) Afeksi: Jurnal Penelitian dan Evaluasi Pendidikan Arus Jurnal Sosial dan Humaniora Almufi Jurnal Pengabdian kepada Masyarakat Jurnal Teknik Informatika Unika Santo Thomas (JTIUST) Jurnal Ekonomi Syariah dan Bisnis Jurnal Karya Abdi Masyarakat Sciences of Pharmacy Electronic Journal Scientific of Environmental Health And Diseases Journal of Economics and Social Sciences Journal of Social Knowledge Education (JSKE) Journal of Medical Studies ZIJEc: Zabags International Journal of Economy ENDLESS : International Journal of Future Studies International Journal Of Health And Social Behavior Journal of Pharmacy Tiara Bunda
dewi, hasna
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The The Correlation of Neutrophil-to-Lymphocyte Ratio with LupusQoL in Systemic Lupus Erythematosus Patients Mahrunnisa Rienti Sepestian; Lipinwati; Dewi, Hasna; Hanina; Nyimas Natasha Ayu Shafira
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40840

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations depending on disease activity. Clinical manifestations, disease activity, and side effects of treatment can affect quality of life. The LupusQoL questionnaire assesses the disease's impact on eight quality of life domains. The Neutrophil-to-Lymphocyte Ratio (NLR) is an inflammatory biomarker that correlates with SLE disease activity. Objective: This research aims to determine the correlation between NLR and various domains of the LupusQoL questionnaire in SLE patients. Methods: This observational analytic study used purposive sampling, involving 32 SLE patients treated at Raden Mattaher Hospital, Jambi, in 2024. NLR was obtained from blood counts performed within the last 4 weeks, and HRQOL was measured using the LupusQoL questionnaire. Data were analyzed using Pearson correlation. Result: The mean NLR was 6.50 (1.3–29.43). LupusQoL showed the lowest score in fatigue (58.85). Pearson analysis revealed a moderate inverse correlation between NLR and the planning domain of LupusQoL (p= 0,022). NLR shows no statistically significant correlation with physical health, pain, intimacy, burden to others, emotional health, body image, or fatigue in SLE patients, as p-values >0.05. Conclusion: Higher NLR is correlated with lower planning domain HRQoL in SLE patients and vice versa.
Ethanolic Extract of Curcuma zedoaria Enhances Burn Wound Healing in Male White Rats Yuliawati, Yuliawati; Kasmadi, Fathnur Sani; Elisma, Elisma; Dewi, Hasna; Afryandes, Amelya; Puteri, Vanya Gita
Sciences of Pharmacy Volume 5 Issue 1
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0501488

Abstract

In addition to its widespread use as a culinary spice, white turmeric rhizome (Curcuma zedoaria (Christm.) Roscoe) exhibits important pharmacological activities, including anti-inflammatory, anticancer, and antioxidant effects. The rhizome contains secondary metabolites such as flavonoids, alkaloids, saponins, phenols, tannins, and terpenoids, which are believed to contribute to its potential efficacy in treating burns. This study used a fully randomized post-test-only control group design consisting of five treatment groups: P1 (5% ethanol extract of white turmeric rhizome), P2 (10%), P3 (15%), K⁺ (positive control: Bioplacenton), and K⁻ (negative control: Vaseline flavum). Parameters observed included reduction in burn wound diameter and collagen density, which were assessed through histological analysis. The results showed significant differences between treatment groups (p < 0.05). The 10% concentration showed the highest wound healing activity, reaching a healing rate of 54.72% and producing denser collagen compared to the other treatments. However, its effect did not exceed the positive control (Bioplacenton). The 5% concentration showed moderate healing activity (43.84%) with intermediate collagen density, while the 15% concentration produced the lowest effect. Overall, the findings indicate that the ethanol extract of white turmeric rhizome, particularly at a concentration of 10%, enhances burn wound healing and increases collagen formation, supporting its potential as a natural therapeutic agent for the treatment of burns.
Efektivitas Video Pembelajaran Anatomi terhadap Pemahaman Mahasiswa Kedokteran Mursalin, Adhywira; Enis, Rina N.; Dewi, Hasna; Miftahurrahmah, Miftahurrahmah; Kusdiyah, Erny; Ramadhan, Ghozi F.
Medical Scope Journal Vol. 8 No. 1 (2026): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v8i1.59564

Abstract

Abstract: Understanding human anatomy, including the digestive system, is fundamental for medical students. Educational videos are increasingly recognized as an effective teaching tool to enhance student comprehension and improve their performance in practical examinations. This study aimed to evaluate the effectiveness of using educational videos on the knowledge and performance of medical students at Universitas Jambi through the practical exam scores. This was a quasi-experimental study with a pre-test and post-test design. There were 123 medical students from the 2024 cohort chosen through purposive sampling. The students were divided into two groups: experimental and control groups. The experimental group was given a video on the anatomy of the digestive system as an instructional tool, while the control group received standard teaching. Data were collected from both groups' pre-test and post-test scores. Data were analyzed using the paired and independent t-tests, which compared the scores within and between the groups to identify any significant differences. The average pre-test and post-test scores were 28.85 and 54.75 for the control group, while of the experimental group were 29.91 and 62.74, respectively. The pre-test scores showed no significant difference (p=0.071), but the post-test scores demonstrated a significant improvement in the experimental group (p=0.032). In conclusion, the educational video of anatomy of the digestive system significantly improved student knowledge and performance at Universitas Jambi. Keywords: anatomy practicum; educational video; medical students   Abstrak: Pemahaman tentang anatomi, termasuk sistem pencernaan, merupakan fondasi yang esensial bagi mahasiswa kedokteran. Video edukasi semakin diakui sebagai media ajar yang efektif untuk meningkatkan pemahaman mahasiswa dan menunjang kinerja mereka dalam ujian praktikum. Penelitian ini bertujuan untuk menilai efektivitas penggunaan media ajar terhadap pemahaman dan kinerja mahasiswa melalui nilai ujian praktikum mahasiswa kedokteran di Universitas Jambi. Jenis penelitian ialah kuasi-eksperimental dengan pre-test dan post-test design. Sebanyak 123 mahasiswa kedokteran dari angkatan 2024 di Universitas Jambi dipilih melalui teknik purposive sampling. Subjek penelitian dibagi menjadi dua kelompok: kelompok eksperimen dan kelompok kontrol. Kelompok eksperimen diberikan video tentang anatomi sistem digestif sebagai alat bantu pembelajaran, sementara kelompok kontrol menerima pembelajaran standar. Data dikumpulkan dari skor pre-test dan post-test kedua kelompok. Efektivitas video dievaluasi dengan analisis uji t berpasangan dan uji t independen untuk membandingkan skor di dalam satu kelompok dan antar kelompok. Hasil penelitian menunjukkan skor re rata pre-test dan post-test kelompok kontrol ialah 28,85 dan 54,75, sedangkan skor kelompok eksperimen ialah 29,91 dan 62,74. Secara statistik, skor pre-test tidak menunjukkan perbedaan bermakna (p=0,071), tetapi skor post-test menunjukkan peningkatan bermakna pada kelompok eksperimen (p=0,032). Simpulan penelitian ini ialah video edukasi mengenai anatomi sistem digestif secara bermakna mampu meningkatkan kinerja mahasiswa di Universitas Jambi. Kata kunci: praktikum anatomi; video ajar; mahasiswa kedokteran
Analisa Imunoekspresi Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) pada Karsinoma Sel Ginjal Subtipe Sel Jernih yang Telah Metastasis dan Tidak Bermetastasis Dewi, Hasna; Hassan, Abdul Hadi; Hernowo, Bethy Suryawati
Majalah Patologi Indonesia Vol 27 No.3, September 2018
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakangKarsinoma sel ginjal subtipe sel jernih (KSGSJ) merupakan keganasan epitelial terbanyak dari seluruh kejadian karsinoma sel ginjal, yang insidensinya menunjukkan peningkatan, dengan angka mortalitas yang masih tinggi. Prognosis KSGSJ akan menurun pada kasus-kasus yang telah bermetastasis. Tujuan penelitian ini untuk melihat peranan penanda molekuler extracelluler matrix metalloproteinase inducer (EMMPRIN) dalam hubungannya dengan kejadian metastasis pada KSGSJ. MetodePenelitian ini dilakukan secara cross sectional analitic terhadap 36 kasus KSGSJ di Departemen Patologi Anatomik Fakultas Kedokteran Universitas Padjadjaran/RSUP Dr. Hasan Sadikin Bandung, yang terdiri atas 18 kasus kelompok non metastasis dan 18 kasus kelompok metastasis. Pemeriksaan semikuantitatif berupa skor imunoreaktif imunohisitokimia EMMPRIN dilakukan terhadap semua kasus.HasilPenelitian ini menunjukkan terdapat perbedaan bermakna antara skor imunoreaktif EMMPRIN pada kelompok KSGSJ metastasis dan non metastasis (p=0,001; OR=34 (3,611-320,10).KesimpulanBerdasarkan hasil penelitian ini didapatkan bahwa semakin kuat imunoekspresi EMMPRIN, semakin besar kemungkinan terjadinya metastasis pada KSGSJ.
Correlation Clinicopathological and Immunohistochemical Expression of Interleukin-6 (IL-6) in Keloid Fairuz Fairuz; Erisca Utami; Hasna Dewi; Fitriyanti Fitriyanti; Miftahurrahma Miftahurrahma; Budi Justitia; Mara Imam Taufiq Siregar; Humaryanto Humaryanto
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.5844

Abstract

IL-6 has been shown to enhance collagen synthesis and prolong the fibroblast proliferative phase, potentially contributing to uncontrolled keloid growth. However, despite its frequent mention in the literature as a crucial factor in keloid formation, studies specifically exploring the molecular mechanisms of IL-6 in fibroblast regulation and its interaction with other cytokines within keloid tissue remain limited. This study aims to further investigate the role of IL-6 in keloid matrix formation. This study is an analytical study conducted cross-sectionally. The samples used were patients diagnosed with keloids histopathologically based on microscopic criteria. Clinical data were taken from medical records and microscopic and immunohistochemical assessments using paraffin blocks available in the anatomical pathology laboratory of hospitals in Jambi city. There were 36 cases of keloids, aged between 12 and 42 years, mostly in women (66.7%), occurring in the trunk area (77.8%) 30 cases of recurrence (83.3%). We found 24 cases (77.8%) with strong IL-6 immunoexpression. There were 3 cases (8.3%) with no immunoexpression. There was a strong correlation between IL-6 immunoexpression and gender (p=0.03), age(0.04) and recurrence (p=0.02). The role of fibroblast cells is very important for the process of collagen formation in wound healing. The role of fibroblast cells is very important for the process of collagen formation in wound healing, where interleukin-6 in various theories and studies supports the process of collagen formation.
Postoperative Intraocular Pressure Changes After Cataract Surgery Using Phacoemulsification Technique at H. Abdul Manap Regional Hospital Jambi During July–September 2025 Hanum Chaira Bahri Aeswarani; Vonna Riasari; Hasna Dewi; Gita Mayani; Lipinwati Lipinwati
International Journal of Health and Social Behavior Vol. 3 No. 3 (2026): August: International Journal of Health and Social Behavior
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhsb.v3i3.655

Abstract

Background: Phacoemulsification is the standard therapy for cataracts; however, postoperative changes in intraocular pressure (IOP) may lead to complications. This study observed changes in IOP on the first and sixth postoperative days and the associated risk factors. Objective: To analyze changes in IOP after phacoemulsification and determine the frequency of related risk factors. Methods: A prospective cohort study was conducted on 31 eyes from 27 patients who underwent uncomplicated phacoemulsification at H. Abdul Manap Regional Hospital Jambi from July to September 2025. IOP was measured on postoperative day 1 and day 6. Data were analyzed using the Wilcoxon Signed Rank test with a significance level of p < 0.05. Results: The majority of patients were male (68%) and aged 60–74 years (48%). Mean IOP decreased significantly from 17.16 mmHg on postoperative day 1 to 14.00 mmHg on day 6 (p = 0.001). Knowledge of wound care and medication adherence were considered good. Corneal edema was observed in 4 cases on day 1 and was not observed on day 6. Postoperative inflammatory symptoms also decreased. Conclusion: Phacoemulsification resulted in a significant reduction in IOP and demonstrated good postoperative outcomes.
Efek Melaleuca Cajuputi terhadap Gambaran Histopatologi Organ Paru Tikus yang Diinduksi Asap Rokok Cantika Dwi; Hasna Dewi; Ahmad Syauqy; Fairuz; Rina Nofrienis
Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Vol. 7 No. 3 (2026): August (Inpres)
Publisher : Mataram University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/goescienceed.v7i3.2946

Abstract

Exposure to cigarette smoke can cause lung tissue damage through mechanisms of chronic inflammation and oxidative stress. Melaleuca cajuputi essential oil contains 1,8-cineole and flavonoids, which possess anti-inflammatory and antioxidant properties, thereby offering potential protective effects on lung tissue. This study aimed to analyze the effects of Melaleuca cajuputi essential oil on the histopathological features of the lungs in cigarette smoke-induced rats. This experimental study used 28 male Wistar rats divided into four groups: negative control, positive control (cigarette smoke exposure), treatment group 1 (cigarette smoke exposure + Melaleuca cajuputi aromatherapy at a dose of 0.5 mL), and treatment group 2 (cigarette smoke exposure + aromatherapy at a dose of 1 mL). The treatments were administered for 30 days, with exposure to two cigarettes per day and aromatherapy for 15 minutes daily. Histopathological parameters assessed included inflammatory cell infiltration and alveolar septal destruction. Data were analyzed using the Kruskal–Wallis test and Mann–Whitney test. The results showed that administration of Melaleuca cajuputi at a dose of 0.5 mL significantly reduced inflammatory cell infiltration scores and alveolar septal destruction compared to the positive control group. Administration of the 1 mL dose significantly reduced inflammatory cell infiltration; however, it did not show a significant difference in alveolar septal destruction compared to the positive control group.
Co-Authors A Syamsi Abdul Hadi Hassan, Abdul Hadi Ade Irma Suryani Adrian, Adek Afryandes, Amelya Agustiansyah, Lukidita Ahmad Hidayat Ahmad Syauqy Ahmad Syauqy Al Hadad, Ahmad Masyuri Ambarsari, Niati Anati Purwakanthi, Anati Anggelia Puspasari Arjmand, Reza ATTIYA ISTARINI Ave Olivia Rahman Bethy Suryawati Hernowo Budi Justitia Cantika Dwi Daud Daud, Daud Dian Andini Ekaputri, Tia Wida Elisma Elisma Enis, Rina N. Erisca Utami Erny Kusdiyah Erwina Kartika Devi Esa Indah Ayu, Esa Indah Fairuz Quzwain Fairuz, Fairuz Fauzan, Randy Febrianto, Heri Fitriyanti Fitriyanti Gita Mayani Hanina Hanina, Hanina Hanina, Hanina Hanum Chaira Bahri Aeswarani Hashim, Emilda Hendra Kasmi Herlambang Herlambang Humaryanto Humaryanto Humaryanto, Humaryanto Humaryanto, Humaryanto Husman, Lipinwati Irawan Anasta Putra, Irawan Anasta Iskandar, Mirna Marhami Ismiyanti, Anissa Juniati, Rianita Kadarsih , Sri Kartika Devi, Erwina Kemal, Amir Kurniawan Kurniawan Kurniawan Lestari, Nur Afni Lipinwati ., Lipinwati Lola’ Tulak Rerung M. Arif Musthofa Mahrunnisa Rienti Sepestian Mara Imam Taufiq Siregar Maslaini Masyanto Miftahurrahma Miftahurrahma Miftahurrahma Miftahurrahmah Miftahurrahmah, Miftahurrahmah Miranda, Melly Muharramah, Delvia Mun'amah, Anatun Nisa Munamah , Anatun Nisa Munip, Al Mursalin, Adhywira Musthofa , M Arif Nisak, Sayida Khoiratun Nur Afni Lestari Nuriyah Nuriyah Nuriyah, Nuriyah Nurjali Nurul Safitri Nyimas Natasha Ayu Shafira Oktaviani, Milla Periadi, Ardiansyah Pitri, Alisyah Puji astuti, Fuji Lestari Puteri, Vanya Gita Putri Sari Wulandari Putri, Hesti Amelia Quzwain, Fairuz Chatib Quzwain, Suhair Rahayu, Della Putri Ramadhan, Ghozi F. Rina Nofri Enis Rina Nofrienis Rini Kartika Riska Marvelia Romadiani, Inaya Sani K, Fathnur Sapriandi Saputra, Ahmad Edi Sari, Rahayu Mustika Saryanti, Saryanti Siti Fatimah Sukiawati, Indah Sunarti, Zeni Teuku Mahmud Tia Wida Ekaputri Utami, Erisca Ayu Vonna Riasari Wargo Wargo, Wargo Wati, Besse Mirna Wendi Rachman Wulandari, Triyana Wulansari, Nadia Yatima, Khusnul Yuliawati Zaenal Abidin Zulfi