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Korelasi antara Gambaran Ultrasonografi dengan Klasifikasi Histopatologi pada Pasien Nodul Tiroid di RSUD Raden Mattaher Jambi Ihsana Taufiqo Muflihah; Chairunnisa; Hasna Dewi
Journal of Medical Studies Vol. 4 No. 1 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i1.31936

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ABSTRACT Background: Thyroid nodules are swellings or masses in the thyroid gland. To establish the diagnosis of thyroid nodules requires ultrasound and histopathological examination. This study aims to determine the correlation between ultrasound results and histopathology in thyroid nodule patients at Raden Mattaher General Hospital Jambi. Method: This research is an analytical research, research method cross-sectional. Sampling with total sampling technique so that the total sample is 50 patients. Results: Of the 50 thyroid nodule patients, 46 patients (92.0%) were female, aged 46-55 years, 12 patients, 12 patients aged 46-55 years (28.0%), benign histopathological features, 6 patients (12.0%), malignant in 4 patients (8.0%), thyroid nodules in the dextra lobe in 22 patients (44.0%), nodule size > 1 cm in 28 patients (56,0%), the number multiple of 26 patients (52.0%), the cystic composition of 20 patients (40,0%), hypoechoic echogenicity of 18 patients (36.0%), edge irregular 20 patients (40.0%), microcalcifications in 13 patients (26.0%), hypervascularization in 10 patients (20%), benign histopathology in 30 patients (60.0%), adenomatous goiter in 18 patients (36.0%) and there is a significant correlation with a p-value < 0.05. Conclusion: There is a significant correlation between ultrasound results and histopathology in thyroid nodule patients. Keywords: Ultrasonography, Histopathology, Thyroid Nodules ABSTRAK Latar Belakang: Nodul tiroid merupakan pembengkakan atau massa pada kelenjar tiroid. Untuk menegakkan diagnosis nodul tiroid dibutuhkan pemeriksaan ultrasonografi dan histopatologi. Penelitian ini bertujuan untuk mengetahui korelasi antara hasil ultrasonografi dengan histopatologi pada pasien nodul tiroid di RSUD Raden Mattaher Jambi. Metode: Penelitian ini merupakan penelitian analitik, metode penelitian cross sectional. Pengambilan sampel dengan teknik total sampling sehingga jumlah sampel sebanyak 50 pasien. Hasil : Dari 50 orang pasien nodul tiroid, didapatkan pasien berjenis kelamin perempuan sebanyak 46 pasien (92,0%), rentang usia 46-55 tahun sebanyak 12 pasien, usia 46-55 tahun sebanyak 12 pasien (28,0%), gambaran histopatologi jinak sebanyak 6 pasien (12,0%), ganas sebanyak 4 pasien (8,0%), nodul tiroid di lobus dextra sebanyak 22 pasien (44,0%), ukuran nodul > 1 cm sebanyak 28 pasien (56,0%), jumlah multipel sebanyak 26 pasien (52,0%), komposisi kistik sebanyak 20 pasien (40,0%), ekogenitas hipoekoik sebanyak 18 pasien (36,0%), tepi irreguler sebanyak 20 pasien (40,0%), mikrokalsifikasi sebanyak 13 pasien (26,0%), hipervaskularisasi sebanyak 10 pasien (20%), gambaran histopatologi jinak sebanyak 30 pasien (60,0%), adenomatous goiter sebanyak 18 pasien (36,0%) dan terdapat korelasi yang bermakna dengan nilai p value < 0.05. Kesimpulan: Terdapat korelasi yang bermakna antara hasil ultrasonografi dengan histopatologi pada pasien nodul tiroid. Kata Kunci: Ultrasonografi, Histopatologi, Nodul Tiroid
Analisis Kualitas Sediaan Histologi Menggunakan Beeswax Super Grade sebagai Alternatif Pengganti Paraffin Wax dalam Proses Embedding Nadia Wulansari; Hasna Dewi; Rita Halim; Tia Wida Ekaputri Hz; Erisca Ayu Utami
Journal of Medical Studies Vol. 4 No. 2 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i2.36452

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ABSTRACT Background: One of the procedures in making histological preparations is histotechnics. This tissue processing procedure consists of fixation, dehydration, clarification, embedding, blocking, block cutting, and coloring. The media commonly used for embedding and embedding is paraffin. However, paraffin wax contains up to 11 carcinogenic compounds, so an alternative is needed by using beeswax. This study aims to determine whether super grade beeswax can be used as an alternative to paraffin wax in the embedding process. Methods: This study uses a quantitative method with a descriptive analytic research design of an experimental type. The subject of this research was the long-tailed monkey (Macaca Fascicularis) organ. Samples were made of 10 preparations using paraffin and 10 beeswax preparations which would be assessed by the parameters of cell nucleus staining, cytoplasmic staining, color clarity and staining uniformity. The results of all parameters are summed and analyzed using the Mann Whiteney differential test. Results: The quality of histological preparations using beeswax showed adequate staining. The results were analyzed using the Mann Whitney statistical test on samples using paraffin and beeswax each obtained (p > 0.05) which showed that there was no difference. Conclusion: Beeswax can be used as an alternative to paraffin. Further research on block storage resistance and research on other tests such as immunohistochemistry is necessary. Keywords: Embedding, Beeswax, Paraffin ABSTRAK Latar belakang: Salah satu prosedur dalam membuat sediaan histologi adalah histoteknik. Prosedur pengolahan jaringan ini terdiri dari fiksasi, dehidrasi, penjernihan, embedding, blocking, pemotongan blok, dan pewarnaan. Media yang biasa digunakan untuk embedding dan penyematan adalah parafin. Namun, Lilin parafin mengandung hingga 11 senyawa karsinogenik sehingga diperlukan alternatif dengan menggunakan beeswax. Penelitian ini bertujuan untuk mengetahui apakah beeswax super grade dapat digunakan sebagai alternatif pengganti paraffin wax dalam proses embedding. Metode: Penelitian ini menggunakan metode kuantitatif dengan desain penelitian deskriptif analitik yang berjenis eksperimental. Subjek penelitian ini berupa organ hewan coba monyet ekor panjang (Macaca Fascicularis). Sampel dibuat 10 preparat menggunakan parafin dan 10 preparat beeswax yang akan dinilai dengan parameter pewarnaan inti sel, pewarnaan sitoplasma kejernihan warna dan keseragaman pewarnaan. Hasil seluruh parameter dijumlahkan dan diianalisis menggunakan uji beda Mann Whiteney. Hasil: Kualitas sediaan histologi menggunakan beeswax menunjukan pewarnaan adekuat. Hasil penelitian dianalisis menggunakan uji statistik Mann Whitney pada sampel yang menggunakan parafin dan beeswax masing-masing diperoleh (p > 0,05) yang menunjukkan bahwa tidak ada perbedaan. Kesimpulan: Beeswax dapat digunakan sebagai alternatif pengganti parafin. Penelitian lebih lanjut mengena ketahanan penyimpanan blok dan perlu dilakukan penelitian pada tes lain seperti imunohistokima. Kata kunci: Embedding, Beeswax, Parafin
Indonesia saat ini menghadapi Edukasi literasi Keuangan Syariah Siswa/siswi Madrasah Aliyah di Tanjung Jabung Timur Zikri, Khairul; Dewi, Hasna; Hidayat, Wildan Nur; Devi , Erwina Kartika
NEAR: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 1 (2024): NEAR
Publisher : Komunitas Dosen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32877/nr.v4i1.1707

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Penelitian ini bertujuan untuk efektivitas program edukasi literasi keuangan syariah pada siswa Madrasah Aliyah Jauharatul Islamiah di Kabupaten Tanjung Jabung Timur. Program ini mencakup penyampaian materi berbasis bahan dari Otoritas Jasa Keuangan (OJK) mengenai prinsip-prinsip keuangan syariah, investasi halal, dan bahaya investasi ilegal serta pinjaman online yang tidak sesuai syariah. Sebanyak 65 siswa dari kelas X dan XI mengikuti kegiatan ini. Untuk mengukur peningkatan pemahaman, dilakukan uji pre-test dan post-test. Hasil pre-test menunjukkan tingkat literasi awal siswa sebesar 39%, sedangkan hasil post-test meningkat menjadi 52%. Analisis data menggunakan uji Wilcoxon menunjukkan bahwa peningkatan ini signifikan secara statistik dengan nilai p-value sebesar 7.49e-16. Dengan demikian, program edukasi literasi keuangan syariah ini terbukti efektif dalam meningkatkan pemahaman siswa, dan diharapkan dapat memberikan kontribusi dalam membangun kesadaran akan pentingnya pengelolaan keuangan yang sesuai dengan prinsip syariah di kalangan siswa.
Creativity of Fiqih Teachers in Improving Student Learning Atmosphere During Pandemic at MTs Rhoudotun Hasanah Tanjung Jabung Timur Nisak, Sayida Khoiratun; Dewi, Hasna; Munip, Al; Muharramah, Delvia; Wargo, Wargo
Afeksi: Jurnal Penelitian dan Evaluasi Pendidikan Vol 5, No 5 (2024)
Publisher : Pusat Studi Penelitian dan Evaluasi Pembelajaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59698/afeksi.v5i5.320

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This study aims to determine the creativity of fiqih teachers to improve students' learning atmosphere in the cognitive, affective, and psychomotor domains during Covid-19 pandemic. This research uses a qualitative approach using snowball sampling technique. Data collection techniques were carried out using observation, interview and documentation techniques. The results of this study indicate that the innovations made in improving cognitive, affective and psychomotor abilities include:  Teachers apply the quiz game of throwing paper balls to create a fun atmosphere, Teachers also take a scientific approach, provide motivation, good role models for students and hold routine religious activities. Factors that support teacher innovation are internal factors of teacher awareness while external factors of teacher educational background and school contributions. Although limited facilities hinder the innovation process, the school tries to plan the budget for the procurement of the fiqih facilities through the school operational assistance fund gradually.
The Impact of Minimarket Existence on Grocery Store Revenue Wati, Besse Mirna; Abidin, Zaenal; Yatima, Khusnul; Musthofa, M. Arif; Dewi, Hasna; Munip, Al; Mun'amah, Anatun Nisa
Zabags International Journal of Economy Vol. 3 No. 1 (2025): Economic Studies
Publisher : CV. Zabags Qu Publish

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61233/zijec.v3i1.94

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The existence of minimarkets spread across various areas, both urban and rural, has an impact on nearby grocery store traders, causing grocery store traders to experience a decline in income. Because the Indomaret minimarket is a small shop or supermarket that sells most of the daily necessities needed by consumers. Minimarkets are a favorite shopping place for people today who want light shopping but don't need to go far like to the supermarket. This research aims to find out whether there is a significant impact of the existence of minimarkets on grocery store income in Rantau Rasau sub-district. This research method uses a descriptive quantitative type, namely research that emphasizes analysis on numerical data (numbers) which are processed with a statistical model using a simple linear regression equation Y=a+bX. The sample size in this study was 60 respondents, namely grocery store traders around the Rantau Rasau sub-district. The results of this research state that the existence of minimarkets has a significant effect on grocery store income. We can see this: Tcount = 4.198 and Ttable = 1.980 with a significant value of 0.00003 < 0.05, which means it proves that Ho is rejected and Ha is accepted, which means that the existence of minimarkets in Rantau Rasau sub-district has a positive and significant effect on grocery store income.
Kliniko-Sitopatologi Lesi Prekanker Leher Rahim di Klinik Unja Smart Desa Mendalo Darat Kabupaten Muaro Jambi Fairuz, Fairuz; Dewi, Hasna; Nuriyah, Nuriyah; Lipinwati, Lipinwati; Ayudia, Esa Indah; Lestari, Nur Afni
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.739 KB) | DOI: 10.22437/jkam.v5i3.16281

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Kanker serviks merupakan suatu keganasan yang berkembang di daerah leher rahim. Hampir semua kasus, sebesar 99%, terkait dengan infeksi HPV resiko tinggi. Di Indonesia, angka kejadian kanker berada pada urutan ke-8 di Asia Tenggara, dan urutan ke-23 di Asia. Salah satu skrining kanker serviks yang dapat dilakukan yaitu tes pap smear. Tujuan dari penelitian ini adalah untuk melihat gambaran klinis dan gambaran sitopatologi lesi prekanker leher rahim sesuai dengan klasifikasi Bethesda 2014. Lokasi kegiatan dilakukan di Klinik Unja Smart, Mendalo, Kabupaten Muaro Jambi. Variabel klinis yang dinilai adalah usia, paritas, jenis kontrasepsi, menopause, keluhan, riwayat ginekologi dan status lokalis, sedangkan variabel sitopatologinya adalah gambaran lesi prekanker leher rahim menurut kriteria Bethesda 2014. Didapatkan dari kriteria klinis usia rata-rata adalah 40 tahun, multipara, tidak menggunakan KB dan keluhan terbanyak adalah keputihan. Hasil sitopatologi pap smear terbanyak adalah Negative for intraepithelial lesion or malignancy NILM dan diikuti oleh Servisitis kronis non spesifik (CKNS) di urutan kedua. Kesimpulannya adalah gambaran kliniko-sitopatilogi masih menunjukkan keadaan yang normal.
Pemeriksaan Pap Smear Sebagai Skrining Lesi Prekanker Leher Rahim Fairuz, Fairuz; Dewi, Hasna; Kusdiyah, Erny
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.712 KB) | DOI: 10.22437/jkam.v5i3.16681

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Latarbelakang Permasalahan kesehatan reproduksi pada perempuan usia produktif sangat banyak. Salah satu permasalahan yang membuat tingginya tingkat mortalitas perempuan adalah kanker leher rahim. Adanya pemeriksaan sebagai deteksi dini dan penyaring (skrinning) terhadap kanker leher rahim sangat penting dalam menurunkan angka mortalitas Metode Kegiatan ini direncanakan akan diselenggarakan pada bulan Agustus 2019. Lokasi kegiatan akan dilakukan di Klinik Pinang Masak Universitas Jambi. Kegiatan ini dilakukan dengan metode penyuluhan serta pemeriksaan langsung pada peserta kegiatan dan edukasi mengenai pap smear. Hasil Kegiatan dihadiri oleh 35 peserta yang berasal dari civitas akademis dan dharma wanita Universitas Jambi. Setelah penyuluhan dilakukan pemeriksaan pap smear. Sebanyak 19 orang bersedia dilakukan pemeriksaan pap smear. Kesimpulan Pap smear sangat penting dimana tidak hanya efektif untuk mendeteksi (skrinning) kanker leher rahim tetapi juga perubahan sel leher rahim yang dicurigai dapat menimbulkan kanker.
Correlation Clinicopathological and Immunohistochemical Expression of Interleukin-6 (IL-6) in Keloid Fairuz Fairuz; Erisca Utami; Hasna Dewi; Fitriyanti Fitriyanti; Miftahurrahma Miftahurrahma; Budi Justitia; Mara Imam Taufiq Siregar; Humaryanto Humaryanto
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.5844

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IL-6 has been shown to enhance collagen synthesis and prolong the fibroblast proliferative phase, potentially contributing to uncontrolled keloid growth. However, despite its frequent mention in the literature as a crucial factor in keloid formation, studies specifically exploring the molecular mechanisms of IL-6 in fibroblast regulation and its interaction with other cytokines within keloid tissue remain limited. This study aims to further investigate the role of IL-6 in keloid matrix formation. This study is an analytical study conducted cross-sectionally. The samples used were patients diagnosed with keloids histopathologically based on microscopic criteria. Clinical data were taken from medical records and microscopic and immunohistochemical assessments using paraffin blocks available in the anatomical pathology laboratory of hospitals in Jambi city. There were 36 cases of keloids, aged between 12 and 42 years, mostly in women (66.7%), occurring in the trunk area (77.8%) 30 cases of recurrence (83.3%). We found 24 cases (77.8%) with strong IL-6 immunoexpression. There were 3 cases (8.3%) with no immunoexpression. There was a strong correlation between IL-6 immunoexpression and gender (p=0.03), age(0.04) and recurrence (p=0.02). The role of fibroblast cells is very important for the process of collagen formation in wound healing. The role of fibroblast cells is very important for the process of collagen formation in wound healing, where interleukin-6 in various theories and studies supports the process of collagen formation.
Mycobacterium Tuberculosis Identification on Suspected Extra Pulmonary Tuberculosis Patients Lipinwati, Lipinwati; Hanina, Hanina; Wulandari, Putri Sari; Iskandar, Mirna Marhami; Istarini, Attiya; Miranda, Melly; Dewi, Hasna; Juniati, Rianita; Fairuz, Fairuz
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.38458

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Background: Extra Pulmonary Tuberculosis (EPTB) is Tuberculosis infection in organs other than the lungs, like pleura, lymph nodes, abdomen, genitourinary tract, skin, joints and bones, or meninges. The Diagnosis of EPTB is still challenging because symptoms of EPTB is vary, location EPTB is an inaccessible site, and paucibacillary smear. We wanted to know the Mycobacterium tuberculosis identification using the qPCR method on samples of EPTB suspects. Methods: This research was a descriptive research with laboratory experiments. Subjects in this study were all cases of suspected EPTB with clinically diagnosed, thoraks radiographs, colonoscopy, and formalin fixed paraffin embedded (FFPE). DNA extraction was carried out according to  PureLink® Genomic dna extraction kit instructions. The PCR volume 20 ul with 2x QuantiNova SYBR Green PCR Kit, M.tuberculosis Primer IS 6110, and DNA Sample. QPCR temperatures was done with predenaturation at 95 °C for 3 minutes, and followed 45 cycles, consist of denaturation at 95 °C for 15 seconds, annealing at 60 °C for 30 seconds dan extenstion at 72 °C for 30 seconds. PCR was performed with positive and negative controls, and data analysis was based on positive and negative ct controls. Results: From 30 suspect EPTB samples, there are males (56,67%), with age 36-55 yo (50%), site of samples most from gastrointestines (70%), and there are 6 samples (20%) with positive qPCR. Conclusion: qPCR methods can be used for EPTB diagnosis.
SKIN INFECTION PREVENTION EDUCATION FOR STUDENTS OF TANJUNG PASIR AL-AWWABIEN ISLAMIC BOARDING SCHOOL, JAMBI Husman, Lipinwati; Dewi, Hasna; Hanina, Hanina; Fairuz, Fairuz; Wulandari, Putri Sari
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

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Islamic boarding schools are faced health problems with various types of diseases such as skin diseases and TB. Skin diseases can be caused by bacteria, fungi, parasites, which have the potential to be contagious if students does not practice Clean and Healthy Living Behavior (PHBS). For this reason, the community service team from the Faculty of Medicine and Health Sciences, Universitas Jambi provides education regarding PHBS, carries out skin scraping examinations and it’s treatment. PHBS counseling, looking at the level of knowledge from the pretest and posttest results. The objective of this study is to increase knowledge regarding PHBS prevention of skin infections among students at the Tanjung Pasir Al-Awwabien Islamic Boarding School, Jambi. The implementation of community service activities on Sunday, 11 August 2024 at the Tanjung Pasir Al-Awwabien Jambi Islamic Boarding School. The activity is in the form of PHBS counseling for the prevention of skin infections among students boarding at Islamic boarding schools followed by interactive discussions. The counseling was attended by 135 students aged 10 – 20 years, male and female respondents were 74 and 61 people. The respondent's level of knowledge was measured through a questionnaire twice, pretest and posttest which consisted of 13 questions. The results of data analysis from the questionnaire results obtained an average pretest result of 88.5 and an average posttest result of 97.5. There was an increase in the average value of students knowledge regarding PHBS, even though the score was in the very good category. Interactive counseling can increase students' knowledge, and it is hoped that good PHBS knowledge can be applied in their lives.
Co-Authors A Syamsi Ahmad Hidayat Ahmad Syauqy Ahmad Syauqy Al Hadad, Ahmad Masyuri Anati Purwakanthi, Anati Anggelia Puspasari Arjmand, Reza ATTIYA ISTARINI Ave Olivia Rahman Budi Justitia Chairunnisa Daud Daud, Daud Ekaputri, Tia Wida Erisca Ayu Utami Erisca Ayu Utami Erisca Utami Erny Kusdiyah Erwina Kartika Devi Esa Indah Ayu, Esa Indah Fairuz Quzwain Fairuz, Fairuz Febrianto, Heri Fitriyanti Fitriyanti Hanina Hanina, Hanina Hanina, Hanina Hashim, Emilda Hendra Kasmi Hidayat, Wildan Nur Humaryanto Humaryanto Humaryanto, Humaryanto Humaryanto, Humaryanto Husman, Lipinwati Ihsana Taufiqo Muflihah Indarwati, Puput Inriani, Nopita Irawan Anasta Putra, Irawan Anasta Iskandar, Mirna Marhami Juniati, Rianita Kadarsih , Sri Kartika Devi, Erwina Kurniawan Kurniawan Kurniawan Lestari, Nur Afni Lipinwati ., Lipinwati Lipinwati Lipinwati M. Arif Musthofa Mara Imam Taufiq Siregar Marwendi, Reza Okva Maslaini Masyanto Miftahurrahma Miftahurrahma Miftahurrahma Miranda, Melly Muharramah, Delvia Mun'amah, Anatun Nisa Munamah , Anatun Nisa Munip, Al Musthofa , M Arif Nadia Wulansari Nilfatri, Nilfatri Nisak, Sayida Khoiratun Nur Afni Lestari Nuriyah Nuriyah Nuriyah, Nuriyah Nurjali Nurul Safitri Pitri, Alisya Pitri, Alisyah Puji astuti, Fuji Lestari Putri Sari Wulandari Putri, Hesti Amelia Quzwain, Fairuz Chatib Quzwain, Suhair Rahayu, Della Putri Rina Nofri Enis Rini Kartika Riska Marvelia Rita Halim Romadiani, Inaya Ruslan Ruslan Sapriandi Saputra, Ahmad Edi Saryanti, Saryanti Siti Fatimah Sukiawati, Indah Sunarti, Zeni Teuku Mahmud Tia Wida Ekaputri Wargo Wargo, Wargo Wati, Besse Mirna Wulandari, Triyana Wulansari, Nadia Yatima, Khusnul Zaenal Abidin Zikri, Khairul Zulfi