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Apriyanto, Apriyanto
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SISTEM INFORMASI SMA NEGERI 7 LUWU TIMUR BERBASIS WEB Utami, Andi Syahri; Muhallim, Muhlis; Apriyanto, Apriyanto
Jurnal Informatika dan Teknik Elektro Terapan Vol. 13 No. 2 (2025)
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jitet.v13i2.6076

Abstract

Abstark. Tujuan penelitian ini adalah membuat sistem informasi SMA Negeri 7 Luwu Timur. Metode penelitian yang digunakan dalam penelitian ini adalah metode Waterfall. Metode pengumpulan data dalam penelitian dan (1) dokumentasi data; (2) pengamatan; (3) wawancara; dan (5) studi pustaka. Perancangan website yang dibuat menggunakan metode pengembangan Unified Modelling Language (UML) yang terdiri dari use case diagram, activity diagram, entity relationship dan sequence diagram. Adapun software yang digunakan dalam perancangan sistem informasi ini menggunakan bahasa pemrograman PHP, xampp sebagai webserver, dan MySQL sebagai database. Penelitian ini menghasilkan sebuah website yaitu sistem informasi sekolah. Website ini telah diuji dengan menggunakan metode pengujian Black Box. Dengan adanya website ini dapat membantu guru, pengunjung, siswa dan pihak sekolah untuk mengelola data-data yang ada.Abstract. The purpose of this research is to create an information system for SMA Negeri 7 Luwu Timur. The research method used in this study is the Waterfall method. Data collection methods in research and (1) data documentation; (2) observation; (3) interviews; and (5) literature study. The website design is made using the Unified Modeling Language (UML) development method which consists of use case diagrams, activity diagrams, entity relationships and sequence diagrams. The software used in the design of this information system uses the PHP programming language, xampp as the webserver, and MySQL as the database. This research produces a website that is a school information system. This website has been tested using the Black Box testing method. With this website it can help teachers, visitors, students and the school to manage existing data.
Inhibition of Human Acetylcholinesterase (4EY7) using Bioactive Compound from Moringa oleifera: Molecular Docking and Dynamic Studies Utami, Wiji; Apriyanto, Apriyanto; Antari, Laila; Rasyid, Herlina; Fitriani, Ika Nur
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 2, November 2024
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i2.39840

Abstract

Alzheimer's disease is a neurodegenerative disorder caused by acetylcholine hydrolysis that impairs cognitive brain function. This research aims to determine the interaction and dynamic of ligands from Moringa oleifera on AChE through Lipinski's Rule, ADMET properties, molecular docking calculations, and molecular dynamic simulations. Lipinski's Rule calculation provided ligand limits that adhere to druglikeness properties. ADMET results also showed that several ligands satisfy ADMET properties. Pterygospermine has lower binding energy than the ligand control (-10.28 kcal mol-1) with amino acid residues of TYR133 and GLU202. It indicates a favorable interaction between the AChE receptor and ligand in the inhibition process. Based on molecular docking calculations, pterygospermine inhibits the AChE receptor at the Long, narrow aromatic gorge active site. According to molecular dynamic simulations, the MMPBSA energy for pterygospermine is 37.377 kJ mol-1. The samples showed a total average RMSD of 2 Å, suggesting no significant conformational changes throughout the simulation. The sample's average RMSF value is around 2 Å, suggesting favorable interactions with the receptor during simulation. However, this data is different from the ligand control interaction mode. Molecular dynamic investigations of the pterygospermine ligand in the complex revealed the stability and unfolded effect on the protein. The results of this study propose a candidate anti-Alzheimer's ligand from Moringa oleifera against the AChE receptor. In practice, these results can contribute to research studies exploring natural ingredients from plants with medicinal potential in drug discovery. These results can be validated using further research in vitro and in vivo.
PERAN TEKNOLOGI BIG DATA DALAM MENINGKATKAN EFEKTIVITAS MANAJEMEN PENDIDIKAN DI PERGURUAN TINGGI Marlina, Marlina; Saifullah, Saifullah; Apriyanto, Apriyanto; Megavitry, Rissa; Wiliyanti, Vandan; Jaswan, Jaswan
Jurnal Review Pendidikan dan Pengajaran Vol. 7 No. 3 (2024): Vol. 7 No. 3 (2024): Volume 7 No 3 Tahun 2024 (Special Issue)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v7i3.31544

Abstract

Penelitian ini mengkaji peran teknologi Big Data dalam meningkatkan efektivitas manajemen pendidikan di perguruan tinggi. Metode studi literatur digunakan untuk mengumpulkan dan menganalisis informasi dari berbagai sumber terkait penerapan Big Data dalam konteks pendidikan tinggi. Hasil penelitian menunjukkan bahwa penggunaan Big Data dapat secara signifikan meningkatkan efisiensi pengelolaan administrasi perguruan tinggi, memungkinkan pengambilan keputusan yang lebih tepat waktu dan informasional, serta personalisasi pengalaman belajar mahasiswa. Namun, tantangan terkait privasi dan keamanan data perlu diperhatikan dalam implementasi teknologi ini. Oleh karena itu, rekomendasi disarankan untuk mengembangkan kebijakan yang mengatur penggunaan data secara etis dan aman, serta meningkatkan kapasitas staf dalam mengelola dan menganalisis data Big Data. Penelitian ini memberikan kontribusi dalam pemahaman terhadap potensi dan tantangan teknologi Big Data dalam transformasi manajemen pendidikan di perguruan tinggi.
Co-Authors Abduh, Hisma Abed, Yara Abrar Hiswara Adiazmil, Aan Akib, Nur Illyyin Albadri, Albadri Alhamdani, Abdul Kodir Alnisari, Alnisari Andiani, Paramita Anggara, Reddy Antari, Laila Arfan Arfan Arifin , Zainal Arini, Rani Eka Arisondha, Edy Astuti - Aulia, Sofi Azhiman, Fauzan Badia, Esti Bambang Bambang Bunyamin, Ilham Akbar Dasmen, Rahmat Novrianda Dedy Wahyudi Edi Sutanto Edison, Rizki Edmi Erfiani, Mery Fadhliyah Malik Faizal Faizal, Faizal Fardinah, Fardinah Fasli Jalal Fitiria, Zakiatul Frans Sudirjo Gamar Al Haddar, Gamar Al Halid, Zulkifli Halik, Halik Hamzan Wadi Hanim, Saidatul Harun, Lalu Ahmad Hidayat, Deddy Hikmah Hikmah Himawan Sutanto, Himawan Homiswadi, Homiswadi Hossam, Ahmed Ibnusina, Fedri Ika Nur Fitriani Ilyas Y, Muhammad Ilyas Y., Muhammad - Imran, Shintia Agrifa Ali Indriwati Indriwati Intes, Amina Irwanto, Muhamad Ageng Ismiati, Riska Jabbar, Asriullah Jaswan, Jaswan Judijanto, Loso Khadijah Khadijah Laksono, Muflih Adi Latifa Dinar Rahmani Hakim Lesmana, Tera Lestari, Sri Dian Mardiati Mardiati Marius Masri Sadipun Marlin, Nova Marlina Marlina Marningsih, Elfi Maulina, Fina Miftahul Jannah Mirahwati, Mirahwati Mubarak Mubarak Mudawanah, Siti Muhallim, Muhlis Muhammad Nadjib, Muhammad Muhammad Safii Muhibbatun, Muhibbatun Muhtadi, Muhamad Ammar Mukhta, Diniwati Murniawan, Muhammad Wahid Musa Hefer Smas Nampira, Ardi Azhar Nasrudin Nesha, Putu Niken Vincensia Novitasari, Salwa Aulia Nugroho, Agung Yuliyanto Nurhaliza, Ellys Nurhasanah, Dila Padila Nurhidayah Nurhidayah Nurhikma, Nurhikma Nursyam Anaguna NURUL AZIZAH Pangaribuan, Hotma Pascayantri, Asniar Priyana, Yana Purnomo, Adi Dwi Purwinahyu, Purwinahyu Rahmawati, Sri Andlina Rasak, Adriatman Rasyid, Herlina Riana Riana, Riana Rifandi, Muhammad Rinto Suppa Rismayanti Rismayanti Rissa Megavitry Rohana Nur Aini Roni Afrizal Rosadi, Elda Mnemonica Rukmana, Arief Yanto Rusli, Nirwati Saifullah Saifullah Setiani, Dwi Aluh Setiawan, La Ode Roni setiawati, rahmi Setyorini, Dini Sitepu, Ediaman Siti Annisa Wahdiniawati, Siti Annisa Siti Maria Sitti Hasnah Slamet Haryadi Sofyan, Suhikma Solo, Dian Munasari Sono, Mohammad Gifari Suherna, Nana Sulsiah, Sulsiah Supriandi Supriandi, Supriandi Susanty, Sry Susi Susilowati, Susi Susilo, Anton Syahrir, Nur Hilal A. Utami, Andi Syahri Utami, Eva Yuniarti Vandan Wiliyanti Wahyudi Wahyudi wahyuni wahyuni Wahyuni, Ester Dwi Wardani, Chyntia Ayu Wibowo, Teguh Setiawan Wiji Utami, Wiji Winata, Rizki Hardian Wisnianti, Dwi Y, Muhammad Ilyas Yahya, Sitti Rachmawati Zakaria Habib Al-Ra’zie