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25-Hydroxyvitamin D Serum Levels Unrelated to Fasting Blood Glucose Levels of Premenopausal Women in Padang Erasta, Junira; Sulastri, Delmi; Afriwardi
Basic and Applied Nursing Research Journal Vol 1 No 2 (2020): Basic and Applied Nursing Research Journal (BANRJ)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (284.553 KB) | DOI: 10.11594/banrj.01.02.04

Abstract

Introduction: Low serum 25-Hydroxyvitamin D levels in premenopausal women result in the impaired release of insulin from the pancreas and reduce glucose tolerance which causes the body's metabolism to slow down resulting in weight gain leading to insulin resistance and resulting in diabetes mellitus (DM). The incidence of DM occurs at premenopausal ages compared to productive ages, the percentage of women experiencing diabetes is higher than men. This study aims to determine the relationship between 25-Hydroxyvitamin D serum levels and fasting blood glucose (FBG) levels of premenopausal women in Padang. Method: This study was conducted in the city of Padang, is observational, cross-sectional design. The study sample was 62 premenopausal women. Measurement of serum 25-Hydroxyvitamin D levels was measured by enzyme-linked immunosorbent assay and FBG levels were measured by the GOD-PAP method. Data were analyzed using the Pearson correlation test. Results: The average serum level of 25-Hydroxyvitamin D respondents was 30.96 ± 10.96 ng/ml. The average FBG level of respondents was 107.03 ± 13.74 mg/dl. There was no significant relationship between 25-Hydroxyvitamin D serum levels and FBG levels (r = - 0.038, p = 0.769). Conclusion: There is no significant relationship between 25-Hydroxyvitamin D serum levels and FBG levels of premenopausal women in Padang.
Effect of Papaya Seed on Mortality and Midgut Histopathology in Aedes aegypti Larvaes Agustini, Cynthia; Hasmiwati, Hasmiwati; Afriwardi
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p66-75.2025

Abstract

Background: Indonesia is an endemic region for Dengue infection. The World Health Organization (WHO) reported Dengue as one of the top ten global health threats in 2020. Dengue is a viral infection transmitted primarily by the Aedes aegypti mosquito, causing Dengue Fever and Dengue Hemorrhagic Fever. Temephos 1.25% has been the WHO recommended standard larvicide. However, prolonged use and continuously increasing doses may result in resistance and toxicity, posing risks to the environment and human health. This necessitates the discovery of alternative larvicides that are effective in killing larvae with minimal side effects, particularly those derived from natural materials. Methods: This research intends to illustrate the impact of papaya seed extract on the death rate of larvae and the histopathological changes in the midgut of Ae. aegypti larvae. A genuine experimental framework featuring a control group with only post-testing was utilized for this investigation. The sample comprised 750 Ae. aegypti larvae, which were categorized into six groups: one negative control group (aquades), one positive control group (temephos 1. 25%), and four treatment groups using papaya seed extract at varying concentrations of 2 mg/ml (P1), 2. 5 mg/ml (P2), 3 mg/ml (P3), and 3. 5 mg/ml (P4). Results: The results showed that all larvaes died within 24 hours in the positive control, P1, P2, P3, and P4 groups. Probit analysis of papaya seed extract revealed LC50 at 2.599 mg/ml and LC90 at 4.776 mg/ml after 8 hours of exposure. Conclusion: This study concludes that papaya seed extract affects larval mortality and midgut histopathology alterations in Ae.aegypti larvae. These findings indicate that papaya seed extract holds great potential as a natural and environmentally safe as alternative larvicide to disrupt the development of dengue fever vectors.
Elevation of miR-210 Expression and Mean Arterial Pressure as Early-onset Pre-eclampsia Biomarkers, while Elevation of Matrix Metalloproteinase-2 as Late-onset Pre-eclampsia Biomarker Nelvianti Nelson; Yusrawati Yusrawati; Joserizal Serudji; Jamsari Jamsari; Arni Amir; Afriwardi Afriwardi; Erry Gumilar
The Indonesian Biomedical Journal Vol 17, No 2 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i2.3490

Abstract

BACKGROUND: Pre-eclampsia has varying onset patterns, which are challenging to determine due to their association with diverse clinical parameters, including blood pressure regulation, vascular remodeling, and placental hypoxia. These parameters influence the expression of key biomarkers such as microRNAs, metalloproteinases, and arterial pressure indices. Therefore, understanding the associations is crucial for improving early diagnosis and management. This study was conducted to compare miR-210 expression, mean arterial pressure (MAP), and matrix metalloproteinase (MMP)-2 levels between early-onset pre-eclampsia (EOPE) and late-onset pre-eclampsia (LOPE).METHODS: Pregnant women with EOPE (20–34 weeks) and LOPE (35 weeks to term) were included in this cross-sectional comparative study, and their blood samples were collected. miR-210 expression was quantified with reverse transcription polymerase chain reaction (RT-PCR), MAP was measured using sphygmomanometer, while MMP-2 levels were measured using enzyme-linked immunosorbent assay (ELISA).RESULTS: miR-210 expression was more frequently observed in the EOPE group (87.5%) compared to the LOPE group (77.5%), with a significant difference identified between the two groups. The odds ratio for miR-210 expression in EOPE compared to LOPE was 2.03 (95% CI: 1.06–6.72). The MAP was notably higher in the EOPE group (121.15 mmHg) than in the LOPE group (116.15 mmHg), with a significant difference observed. Conversely, MMP-2 levels were significantly higher in the LOPE group (390.99 ng/mL) compared to the EOPE group (271.35 ng/mL).CONCLUSION: There are significant differences in miR-210 expression, MAP and MMP-2 between EOPE and LOPE. These findings suggest that miR-210, MAP, and MMP-2 could be useful biomarkers for distinguishing between EOPE and LOPE, potentially guiding more effective management and intervention strategies.KEYWORDS: miR-210, MAP, MMP-2, EOPE, LOPE, pre-eclampsia
Risk Factors for Olfactory Dysfunction in Hospital Setting Following Covid-19 Infection Among Hospital Employees Following Treatment of Covid-19 Infected Patients: A Survey Research Dolly Irfandy; Afriwardi Afriwardi; Bestari J. Budiman; Andani E. Putra; Dwitya Elvira; Claudia Triananda
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 7 (2025): SENTRI : Jurnal Riset Ilmiah, Juli 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i7.4272

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Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To reveal the risk factors for olfactory dysfunction in employees with COVID-19 in the workplace of the subject hospital in Indonesia. This study was quantitative and descriptive, using data from questionnaires distributed to subject hospital in Indonesia employees who have experienced COVID-19. This study shows that anosmia (33.2%) is the most common olfactory dysfunction in COVID-19. COVID-19 infection often occurs in resident doctors (58.1%); women (55.6%); those aged 55 years (92.3%); those with comorbidities such as hypertension (4.3%) and obesity (65%); nonsmokers (91.5%) and smokers 10–20 cigarettes per day (5.1%); and nondrinkers (100%). Anosmia is the most common olfactory dysfunction in COVID-19. It is commonly experienced by resident doctors, women aged ≥55 years, employees without comorbidities, obese employees, nonsmokers, and nondrinker
HUBUNGAN DERAJAT NYERI LOW BACK PAIN DENGAN TINGKAT KEBUGARAN JASMANI PADA LANJUT USIA DI WILAYAH KERJA PUSKESMAS PADANG KANDIS KECAMATAN GUGUAK KABUPATEN LIMAPULUH KOTA Muhammad Bintang Alvinanda; Roza Mulyana; Afriwardi Afriwardi; Fika Tri Anggraini; Rose Dinda Martini; Malinda Meinapuri
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2026): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v3i2.2619

Abstract

Low back pain (LBP) is pain felt in the lower back. Many factors can cause a decrease in physical fitness, one of which is LBP. This study aims to determine the relationship between the degree of LBP pain and the level of physical fitness in elderly people in the Padang Kandis Community Health Center, West Sumatra Province. This study is an observational analytical study with a cross-sectional design. The subjects of this study were 47 elderly people who met the inclusion and exclusion criteria and were selected using the consecutive sampling method. Data collection was carried out through a survey including a VAS (Visual Analog Scale) questionnaire, LBP (Low Back Pain), PAR-Q (Physical Activity Readiness Questionnaire), and a Six Minute Walking test. Data analysis was carried out using the Chi-Square test. The results of the data analysis obtained a p value = 0.457 (p > 0.05) for the relationship between the degree of LBP pain and the level of physical fitness. The conclusion of this study is that there is no relationship between the level of LBP and the level of physical fitness in elderly people in the Padang Kandis Community Health Center, Guguak District, Lima Puluh Kota Regency, West Sumatra Province.   Low back pain (LBP) adalah rasa sakit yang dirasakan di punggung bagian bawah. Banyak faktor yang dapat menyebabkan penurunan kebugaran jasmani salah satunya adalah LBP. Penelitian ini bertujuan untuk mengetahui hubungan derajat nyeri LBP dengan tingkat kebugaran jasmani pada lansia yang berada di wilayah kerja Puskesmas Padang Kandis Provinsi Sumatera Barat.  Penelitian ini merupakan penelitian analitik observasional dengan desain cross-sectional. Subjek penelitian ini didapatkan sebanyak 47 lansia yang memenuhi kriteria inklusi dan eksklusi yang telah dipilih dengan metode consecutive sampling. Pengumpulan data dilakukan melalui survei yang meliputi kuesioner VAS (Visual Analog Scale), LBP (Low Back Pain), PAR-Q (Physical Activity Readiness Questionnaire) dan tes Six Minute Walking. Analisis data dilakukan dengan uji Chi-Square. Hasil analisis data didapatkan nilai p = 0,457 (p > 0,05) untuk hubungan antara derajat nyeri LBP dengan tingkat kebugaran jasmani.  Kesimpulan penelitian ini tidak terdapat hubungan antara tingkat LBP dengan tingkat kebugaran jasmani pada lansia di wilayah kerja kerja Puskesmas Padang Kandis Kecamatan Guguak Kabupaten Lima Puluh Kota Provinsi Sumatera Barat.   
Relationship Between Dried Amnion Sheet and Dry Powdered Amnion with Changes in Wound Area in Acute Wounds Ferdinand Ferdinand; Afriwardi Afriwardi; David Sontani Perdanakusuma; Hirowati Ali
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6906

Abstract

Dried sheet amnion has long been used as a wound treatment that provides better results than standard general care. In addition to dried amnion sheet, dry powdered amnion preparations have begun to be used for wound care. This study aims to evaluate the effectiveness of dry powdered amnion compared to dried amnion sheets in wound healing, and to compare both treatments with standard acute wound care. Sixty-three healthy Wistar rats were randomly divided into three groups: dried amnion sheet treatment group, dry powdered amnion treatment group, and standard wet wound care control group. The research procedure began with the administration of anesthesia using penthotal at a dose of 10mg/kgBW intramuscularly. The backs of the rats were shaved and a 2x1cm wound was designed using a GOAL razor blade after disinfection with 10% betadine solution and 1:30 savlon. Wounds were made on the backs of the rats, and treatments were given according to the group. The wound area was evaluated at time points 6 hours after treatment, day 2 and day 5. Statistical analysis was performed to compare the effectiveness of the treatments. Both treatments with dry powdered amnion and dried amnion sheets significantly reduced the wound area compared to the control group. However, treatment with dried amnion sheets showed higher efficacy in reducing wound area compared to treatment with dry powdered amnion. Statistical analysis confirmed significant differences in wound area reduction between groups. Dry powdered amnion and dried amnion sheets were effective in reducing wound area compared to standard wet wound care. Treatment with dried amnion sheets showed greater efficacy than treatment with dry powdered amnion.
IDENTIFIKASI MASALAH DAN PENYULUHAN KESEHATAN PADA LANJUT USIA DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Zelly Dia Rofinda; Yulistini Yulistini; Afriwardi Afriwardi; Eti Yerizel; Siti Nurhajjah; Elmatris Sy; Elizabeth Bahar
Jurnal Hilirisasi IPTEKS Vol. 2 No. 1 (2019)
Publisher : LPPM Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jhi.v2i1.354

Abstract

Pelayanan kesehatan terhadap lanjut usia (lansia) perlu mendapatkan perhatian khusus, karena lansia rentan terhadap penyakit Tujuan: Pengabdian masyarakat ini dilakukan dengan tujuan untuk mengidentifikasi faktor risiko penyakit dan memberikan penyuluhan pada kelompok lanjut usia di Kenagarian Sumanik. Metode: Kegiatan yang dilakukan adalah pemeriksaan kesehatan lanjut usia dan pengkajian psikologis dengan menggunakan kuisioner DASS 42. Selanjutnya dilakukan penyuluhan kesehatan dengan harapan meningkatkan pengetahuan para lansia sehingga mampu mengidentifikasi tanda bahaya dan mendapat pertolongan lebih awal. Hasil: Kegiatan dihadiri oleh 63 orang warga, 31 orang diantaranya di atas usia 60 tahun. Hasil pemeriksaan ditemukan 22 orang mengalami hipertensi stadium 2, dan 5 orang menderita diabetes yang sebelumnya sudah diketahui akan tetapi kontrol tidak teratur. Pada pemeriksaan mata terdapat 25 orang menderita gangguan refraksi, 5 orang ekstensi lensa dan dirujuk ke RSUD melalui Puskesmas. Dari kajian psikologis didapatkan 5 orang memiliki gejala depresi, 15 orang dengan ansietas dan 48 orang mengalami stress-psikologis. Kesimpulan: Penyuluhan kesehatan sangat diperlukan terutama kelompok lanjut usia supaya lansia dapat mengenal tanda-tanda penyakit sehingga dapat pelayanan kesehatan lebih dini. Aktivitas fisik seperti berolahraga diperlukan namun lansia perlu mengetahui jenis olah raga yang tepat sesuai dengan usia.
Prevalensi serta Analisis Faktor Risiko Chronic Ankle Instability pada Mahasiswa dengan Riwayat Ankle sprain Donal Syafrianto; Umar Umar; Afriwardi Afriwardi
Jurnal Sporta Saintika Vol 11 No 1 (2026): Jurnal Sporta Saintika Edisi Maret 2026
Publisher : Departemen Kesehatan Dan Rekreasi Fakultas Ilmu Keolahragaan Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/sporta.v11i1.568

Abstract

Ankle sprain is one of the most common musculoskeletal injuries in sports and frequently progresses to Chronic Ankle Instability (CAI). This condition is characterized by recurrent episodes of ankle giving way, neuromuscular control deficits, and an increased risk of recurrent injury. This study aimed to determine the prevalence of CAI among university students with a history of ankle sprain using the Cumberland Ankle Instability Tool (CAIT) and to analyze the association between several risk factors and the occurrence of CAI. This study employed a cross-sectional observational design. The sample consisted of 50 students with a history of ankle sprain. Data were collected using a demographic questionnaire and the CAIT instrument. Descriptive statistics were used to determine CAI prevalence, and Chi-square analysis was applied to examine the association between risk factors and CAI. CAI was defined as a CAIT score ≤24. The findings showed that 72% of participants were classified as having CAI, while 28% were categorized as non-CAI. Statistical analysis revealed that recurrent ankle sprain was significantly associated with CAI (p = 0.008). In contrast, sex and athletic participation were not significantly associated with CAI (p > 0.05). The prevalence of CAI among students with a history of ankle sprain is relatively high. Recurrent ankle sprain appears to be the most significant risk factor contributing to CAI. These findings highlight the importance of sensorimotor and neuromuscular rehabilitation programs in physiotherapy practice to prevent the development of CAI.
Peningkatan Pengetahuan Aktivitas Fisik pada Siswa Sekolah Dasar melalui Edukasi Kedokteran Olahraga Desy Nofita Sari; Rahmat Syawqi; Miftah Irramah; Afriwardi Afriwardi; Arni Amir; Lili Irawati; Yose Ramda Ilhami; FIka Tri Anggraini; Hendra Permana; Mutia Lailani
Poltekita: Jurnal Pengabdian Masyarakat Vol. 7 No. 2 (2026)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v7i2.4378

Abstract

Rendahnya pemahaman mengenai pentingnya aktivitas fisik pada anak usia sekolah dasar dapat berdampak pada pembentukan gaya hidup sedentari sejak dini. Kegiatan pengabdian masyarakat ini bertujuan meningkatkan pengetahuan siswa melalui edukasi kedokteran olahraga di SDIT Adzkia Padang. Intervensi dilakukan melalui penyuluhan terstruktur dan demonstrasi aktivitas fisik, dengan evaluasi penilaian awal dan penilaian akhir. Tingkat pengetahuan siswa dievaluasi sebelum dan sesudah intervensi menggunakan tes tertulis dan dianalisis secara deskriptif untuk mengidentifikasi tingkat pengetahuan siswa. Hasil kegiatan menunjukkan adanya peningkatan tingkat pengetahuan setelah edukasi, yang ditandai dengan meningkatnya proporsi nilai pada kategori tinggi serta tidak ditemukannya lagi nilai pada kategori rendah. Temuan ini menunjukkan bahwa edukasi kedokteran olahraga yang terstruktur dan interaktif efektif dalam meningkatkan pemahaman siswa mengenai aktivitas fisik. Oleh karena itu, kegiatan ini dapat digunakan sebagai pendekatan promotif berbasis sekolah untuk mendukung pembentukan perilaku hidup aktif pada anak usia dini.
Co-Authors Adang Bachtiar Adrul Fauzan Afrinita Eka Fitri Agustini, Cynthia Ahmad Wira Aisyah Elliyanti Akdri Andi Alya Misdhal Rini Amanda Besta Rizaldy Amir, Arni Andani E. Putra Antoni, Adi Arina Widya Murni Arni Amir Arni Amir Asril Zahari Asterina Asterina Aulia Fash Farabi Ayu Anissa Bahri Azis, Putri Nurul Syafirah Bestari J. Budiman Biomechy Oktomalioputri, Biomechy Bobby Indra Utama Brian Sri Prahastuti Citra Manela Claudia Triananda Daan Khambri Dara, Widia David Sontani Perdanakusuma Dedi Sutia Dedy Kurnia Delmi Sulastri Delmi Sulastri Desmawati Desmawati Desrida Desrida Desy Nofita Sari Detty Iryani Dezi Ilham Dhiaulhaq, Zalva Indira Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Didin Kustantiningtyastuti Dina Arfiani Rusjdi Donal Syafrianto Dwitya Elvira Edison Edison Efendi, Nursyirwan Efrida Efrida Eka Nofita Eldi Sauma Elizabeth Bahar Elizabeth Bahar Elmatris Sy Elsa Noftalina Endang Mutiwara Endrinaldi Eny Yantri Erasta, Junira Erin Desweni Ermayanti, Sabrina Erry Gumilar Eryati Darwin Eti Yerizel Eva Decroli Fadhilati Sabrina Fadilla, Utami Budhi Febby Herayono Ferdinand Ferdinand Fereshti Lailani Fika Anggraini Fika Anggraini Fika Tri Anggraini FIka Tri Anggraini Ghozi Natul Isral Gusriyani, Sri Gusti Revilla Hardisman Harie Satria ES Haslan Muhaimin Lubis Hasmiwati Hendra Permana Hendriati, Hendriati Hidayati Hidayati Hirowati Ali Hudila Rifa Karmia Husna Yetti Husnil Kadri Ilhami, Yose Ramda Ilmiawati, Ilmiawati Ilvira Ulpa Ismail Intan Nurwida Hayati Yasrial Iria Ningsih Busri Jamsari Jamsari Johanes C. Mose Joserizal Serudji Julizar Julizar Julizar Julizar Julizar Julizar Lastri Daniati Lili Irawati Lili Irawati Malinda Meinapuri Masrul Syafri Mayetti Mayetti Meidiza Ariandiny Mety Dwi Putri Eszy Miftah Irrahmah Miftah Irrahmah Miftah Irramah Miftah Irramah Miftahul Jannah Milfa Sari Muzamil Mohamad Reza Mudjiran Muhammad Amirul Ihsan Saputra Muhammad Bintang Alvinanda Musrizal Adli Mutia Lailani Najirman Najirman Nega Olavia Nelvianti Nelson Noverika Windasari Nur Afrainin Syah Nur Indrawati Lipoeto Nur Indrawaty Lipoeto Nurfazlina Nurfazlina Nurhajjah, Sitti Nuzulia Irawati Pratiwi, Yuharika Prayitno, Irwan Pudia M. Indika Putri Anindita Putri Nurul Syafirah Azis Putri, Biomechy Oktomalio Rahmad Syawqi Rahmad Syawqi Rahmat Syawqi Raisa Hussein Rama Feriska Putra Rani Ashari Reny Jayusfani Restu Susanti Reza Ekatama Rajasa Rika Susanti Rina Gustia Rini Gusya Liza Rini Gusya Liza, Rini Gusya Rita, Rauza S. Ritonga, Sukhri Herianto Rizki Hidayah Rizqa Fiorendita Hadi Rose Dinda Martini Roza Mulyana Rozi Sastra Purna Rurin Ardiyanti Russilawati, Russilawati Sabrina Hayati Safitri, Yunni Salman Umar Salman Umar Salwi, Hanifah Emilia Samosir, Nova Relida Selfi Renita Rusjdi Setia Budi Zein Shafira Widia Putri Siska Andriani Rukmana Siti Coryniken Siti Nurhajjah Sukri Rahman susi susi Syawqi, Rahmat Taufik Hidayat Taufik Hidayat Tiffany Atia Aristi Umar Umar Vaulinne Basyir Vaulinne Basyir Vitresia, Havriza Wahyu Margi Sidoretno Wenny Rahmalia Rezki Wira Ditya Wirsma Arif Harahap Yessy Susanty Sabri Yolanda Syahdia Yose Ramda Ilhami Yose Ramda Ilhsmi Yufri Aldi Yulistini, Yulistini Yuniar Lestari Yusnawati Yusnawati Yusrawati Yusrawati Yusri Dianne Jurnalis Zelly Dia Rofinda