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Journal : JURNAL FARMASIMED (JFM)

EFEKTIVITAS ANALGETIK EKSTRAK ETANOL AKAR ALANG-ALANG (Imperata cylindrica (L) Beauv ) PADA MENCIT PUTIH JANTAN Kartika, Dewi; Gultom, Veronika Yuliyani; Sitompul, Andelila Suprianti
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.374

Abstract

Pain is an unpleasant sensory and emotional experience due to tissue damage, either actual or potential or described in the form of damage. Provision of therapeutic doses of analgesics relieve pain or suppress. Plants Imperata cylindrica L. Beauv empirically used as traditional medicine. The purpose of this study to know the analgetic effect of root ethanol extract of alang-alangImperata cylindrica L. Beauv. This study was done by infra red (IR) plantar test method with a wavelength of 96 nm. Twenty male mice were divided into 4 groups. Three groups were given ethanol extract of Imperata cylindrica L. Beauv branches at a doses of 15 mg/kg bb, 30 mg/kg bb 60 mg/kg bb and one group was given 0,5% CMC Na (control) orally. After that, the time (second) hold infra red induction of pain every 10 minutes to 60 minutes. The data obtained were processed using one-way analysis of variance (ANOVA) and followed test the level of 95%. The results of phytochemical screening Imperata cylindrica L. Beauv is alkaloid, flavonoid, and steroid/triterpenoid. Ethanol extract Imperata cylindrica L. Beauv dose of 15 mg/kg bb average induction able to withstand pain of 12,86; 14,34; 15,44; 19,2; 17,52; 15,42 second, the dose of 30 mg/kg bb 13,6; 17,08; 19,82; 18,44; 16,9; 16,48 second, and a dose of 60 mg/kg bb 16,96; 18,9; 18,94; 22,14; 18,0; 17,26 second. Pain is an unpleasant sensory and emotional experience due to tissue damage, either actual or potential or described in the form of damage. Provision of therapeutic doses of analgesics relieve pain or suppress. Plants Imperata cylindrica L. Beauv empirically used as traditional medicine. The purpose of this study to know the analgetic effect of root ethanol extract of alang-alangImperata cylindrica L. Beauv. This study was done by infra red (IR) plantar test method with a wavelength of 96 nm. Twenty male mice were divided into 4 groups. Three groups were given ethanol extract of Imperata cylindrica L. Beauv branches at a doses of 15 mg/kg bb, 30 mg/kg bb 60 mg/kg bb and one group was given 0,5% CMC Na (control) orally. After that, the time (second) hold infra red induction of pain every 10 minutes to 60 minutes. The data obtained were processed using one-way analysis of variance (ANOVA) and followed test the level of 95%. The results of phytochemical screening Imperata cylindrica L. Beauv is alkaloid, flavonoid, and steroid/triterpenoid. Ethanol extract Imperata cylindrica L. Beauv dose of 15 mg/kg bb average induction able to withstand pain of 12,86; 14,34; 15,44; 19,2; 17,52; 15,42 second, the dose of 30 mg/kg bb 13,6; 17,08; 19,82; 18,44; 16,9; 16,48 second, and a dose of 60 mg/kg bb 16,96; 18,9; 18,94; 22,14; 18,0; 17,26 second.
EFEKTIVITAS KERASIONALAN PEMBERIAN ANTIDIABETIK PENGOBATAN ORAL PASIEN DIABETES MELLITUS PADA USIA 30-50 TAHUN TIPE 2 DI RAWAT INAP PENYAKIT DALAM RSUD DELI SERDANG LUBUK PAKAM TAHUN 2020 Sebayang, Loraetta Brety; Anna Teresia Marbun, Romauli; Kartika, Dewi
Jurnal FARMASIMED (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v3i2.582

Abstract

Background: Diabetes Mellitus is a chronic condition, which occurs because the body cannot produce insulin, normally or insulin cannot work effectively. Objective: To determine the effectiveness of the rational administration of antidiabetic, oral treatment of diabetes mellitus patients at the age of 30-50 years type 2 in Deli Serdang Hospital, lubuk pakam in 2020. Method: This study is a non-experimental type of research using descriptive methods. Results: Shows that from 72 samples of Type II Diabetes Mellitus patients at Deli Serdang General Hospital, April-July Period 2020. With the number (52.8%) of male sex patients and the number (47.2%) of type patients female genitalia and antidiabetic drugs most widely used by patients, in the period of April-July 2020, namely (20.8%) glycionion + metformin and (20.8%) insulin drugs. the use of DM drugs with the right rational indication (65.3%), Rational with the right medicine (100%), rational with the right dosage (100%), the right rational patient (100%) and the rational way of administration (100:%). Conclusion: Evaluation of drug use is a structured quality assurance process that is carried out continuously to ensure that the drugs used are appropriate, safe, and efficient.
FORMULASI EKSTRAK DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) SEBAGAI MASKER GEL PEEL OFF Kartika, Dewi; Atikah, Lulu; Pratiwi, Asti
Jurnal FARMASIMED (JFM) Vol 4 No 1 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i1.801

Abstract

Pandan wangi (Pandanus amaryllifolius Roxb) adalah tanaman yang mengandung alkaloid kimia, flavonoid, tanin, dan polifenol. Penelitian ini bertujuan untuk mengetahui apakah daun pandan wangi dapat diformulasikan sebagai masker gel peel of untuk melembabkan kulit. Ekstrak daun pandan wangi dibuat dalam konsentrasi 0% (blanko), 2,5%, dan 5% yang dibuat dalam sediaan 30 gram. Uji yang dilakukanmeliputi organoleptik, homogenitas, pH, persiapan waktu kering, dan kelembapan. Hasil penelitian menunjukkan bahwa ekstrak daun pandan wangi dapat dibuat sebagai bentuk masker gel dan memenuhi evaluasi fisik bentuk. Hasil tes homogenitas menunjukkan sediaan homogen, pH dalam kisaran 6.0 yang relatif aman pada permukaan kulit wajah. Waktu persiapan mengering selama 30 menit dan memenuhi persyaratan waktu pengeringan. Kemampuan untuk melembabkan kulit lebih besar dengan meningkatkan konsentrasi ekstrak yang ditambahkan. Kemampuan rata-rata tertinggi untuk melembabkan kulit adalah 39,0%. dalam tes kelembaban konsentrasinya adalah 5% ekstrak daun harum pandan karena kulit masker gel pelembab alami sangat baik. Kesimpulannya menunjukkan bahwa ekstrak daun pandan wangi dapat diformulasikan menjadi masker gel peel off yang memiliki kemampuan melembabkan kulit.
ANTIBACTERIAL ACTIVITY OF KERSEN LEAF EXTRACT (MUNTINGIA CALABURA L) AGAINST STAPHYLOCOCCUS AUREUS Kartika, Dewi; Marbun, Romauli Anna Teresia; Dewi, Ayu Puspita
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1012

Abstract

Kersen (Muntingia calabura) is a shady plant that is usually used as a shade. Cherry leaves contain several secondary metabolites such as flavonoid, tannin and terpenoid. Flavonoid can inhibit bacterial growth by denaturing proteins and damaging cell membranes and dissolving fats contained in cell walls. According to the World Health Organization as many as 25 million deaths worldwide in 2011, one third were caused by infectious diseases. One of the most common infectious diseases caused by the bacterium Staphyloccus aureus. The purpose of this study was to see whether the 96% ethanol extract of cherry leaves had antibacterial activity against Staphylococcus aureus. The concentration of the extract used was 15%, 30%, 45% and 60%. From the test results, it can be concluded that the largest inhibition zone diameter is at a concentration of 60% with an inhibition zone diameter of 6.78 mm and the smallest at a concentration of 30%, which is 0.42 mm. Concentration of 45% has (weak) activity inhibiting bacterial growth with an inhibition zone of 2.13 mm, while at a concentration of 15% it has no activity in the inhibition zone of bacterial growth.
COVID-19 PREPAREDNESS ANALYSIS OF DELI SERDANG REGIONAL GENERAL HOSPITAL LUBUK PAKAM INDONESIA Kartika, Dewi; - Matury, Herlina J. El; Karo-Karo, Tati Murni; Kasim, Felix
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1276

Abstract

Indonesia menghadapi berbagai bencana alam dan non alam seperti gempa bumi, tsunami, banjir, tanah longsor, gunung berapi, pandemi COVID-19. Fasilitas pelayanan kesehatan harus dapat diakses dan berfungsi selama dan segera setelah bencana. Penelitian ini bertujuan untuk mengkaji kesiapsiagaan Rumah Sakit Umum Daerah Deli Serdang dalam menghadapi pandemi COVID-19. Penelitian ini menggunakan pendekatan metode campuran. Pengumpulan data dilakukan melalui wawancara, observasi, dan telaah dokumen dengan mengacu pada pedoman dalam WHO Checklist COVID-19. Variabel yang diteliti adalah kepemimpinan dan sistem manajemen dengan percent achievement 93%; koordinasi dan komunikasi 92%; survailans dan manajemen informasi 92%; komunikasi risiko dan keterlibatan masyarakat 100%; administrasi, keuangan dan keberlanjutan bisnis 69%; SDM 75%; surge capacity 80%; keberlanjutan layanan pendukung esensial 83%; manajemen pasien 63%; kesehatan kerja, mental dan dukungan psikososial 70%; identifikasi dan diagnosis cepat 92%; pencegahan dan pengendalian infeksi 84%. Skor indeks keselamatan adalah 0,826 yang di klasifikasikan pada level A, rumah sakit siap menghadapi pandemi COVID-19, namun tetap perlu dilakukan usaha pencegahan jangka panjang untuk meningkatkan keselamatan bencana.
EVALUATION OF THE USE OF ANTIHYPERTENSION DRUG IN HYPERTENSION PATIENTS AT THE GRANDMED LUBUK PAKAM HOSPITAL INSTALLATION IN 2022 Kartika, Dewi; ., Suprianto; Atika, Nur
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1613

Abstract

Hypertension is a condition where there is an increase in blood pressure that exceeds the normal limit, namely systolic blood pressure of more than 140 mmHg and diastolic blood pressure of more than 90 mmHg. Most women suffer from hypertension because of the hormone estrogen. Patients with hypertension who are not given proper therapy will cause complications that can worsen the condition of hypertension. The higher the prevalence of hypertension sufferers, the use of antihypertensive drugs will increase. This will increase the risk of irrational use of antihypertensive drugs. The purpose of this study was to evaluate the rationality of the use of antihypertensive drugs in the Inpatient Installation of Grandmed Lubuk Pakam Hospital based on the right patient, the right indication, the right drug and the right dose. This research is a type of descriptive research. Data collection was carried out retrospectively by using past data in the form of medical records of hypertension patients for the period January 2021 – February 2022 which met the exclusion and inclusion criteria. The sampling technique used was the purposive sampling technique. The results of this study indicate that the most widely used antihypertensive drugs are combination therapy with Calcium Channel Blokers (CCB) + Angiotensin Converting Enzyme Inhibitors (ACEI) (30,6%); Calcium Channel Blokers (CCB) sebanyak (11%); Calcium Channel Blokers (CCB) + Angiotensin Converting Enzyme Inhibitors (ACEI) + Diuretik sebanyak (11,1%); while the low class of drugs is Calcium Channel Blokers (CCB) + Angiotensin Converting Enzyme Inhibitors (ARB) + Angiotensin Converting Enzyme Inhibitors (ACEI); and diuretics + Angiotensin Converting Enzyme Inhibitors (ACEI) were used (2,8%). The results showed that the rationality of the use of antihypertensive drugs obtained was that the patient was correct 100%, the indication was 100%, the drug was 97,2%, and the dose was 97,2%.
Co-Authors - Matury, Herlina J. El Abdul Kasim Achmad Abdul Pandi Abdul Rachman Ade Irma Suryani Agus Junaidi Aldri Frinaldi Amalia Khairunnisa, Amalia AMALIYAH, FITRI Amanda, Retno Tri Ambarita, Mei Isabella Amelia, Firda Resti Andi Ade WR Andri Widianto Anindita, Ajeng Anita Karunia Anna Khumaira Sari Anna Teresia Marbun, Romauli Anugrah, Dias Anugrah APRIANI, DEVI Aprianti, Nurul Arieny, Mutiara Arif Suryo Priyatmojo Arip Rifki Ridwanudin Arum Kartika Sari Arum, Nur Aini Dwi Aryanto Aryanto Astrina, Ika Atika, Nur Atikah, Lulu Attamimi, Fathimah Azzahra Ayu Nurkhasanah Azhara, Desiya Ramayanti Bahri Kamal, Bahri Bambang Agus Pramuka Bambang Setiawan Basti Andriyoko Bellya Affan Roes Bustam, Betty Mauli Rosa Cek Dara Manja Cut Nurliza Debi Meilani Dede Puspa Pujia Deni Setiawan Dennis Devi Hartati Devi Safitri Dewi, Ayu Puspita Dudy Syafruddin, Dudy Ervina Sofyanti Fahma Shufyani Faturakhim, Faturakhim Felix Kasim Ferida, Arifany Fifi Ishak Firmansyah Adiputra Fitri Yunita Batubara Fitri Yunita Batubara, Fitri Yunita Fitriyaningsih, Fatma Ghea Dwi Rahmadiane, Ghea Dwi Gita Ismi Fauziyah Gultom, Veronika Yuliyani Gunadi, Wachjudi R Gusti Zulkifli Mulki Harahap, Nurcahaya harisandi, Prasetyo Hasan, Imam Hastin Hawa Athaya Dheanda Rusminto Heliza, Vini Hendra, Surya Hermanto Hesti Listiyani Hetika Hetika, Hetika Hutahaean, Selly Wanti Ida Farida Ida Farida Ina Ratnamiasih Indah, Suci Irmawati, Ilmi Islami, Afita Din Istiqomah, Anisah Jaja Jaja Jhon Patar Sinurat Johan Mohammad Palah Karunia, Anita Khoerunnisa, Ulfi Kholifah Fil Ardhi Kirana, Rida Nanda Kosidah, Kosidah Krisdiawati, Krisdiawati Krisdiyawati Kusumaputra, Juliani Kusyani, Diah Lolla, Rika Andria Loraetta Brety Sebayang M. Rizki Wahyu Ramadhan M. Zulkarnain Maming, Ratnawaty Maria Agustina Pardede Maulani, Chaerita Maulidah, Hikmatul Maulidia, Siti Asiyah Mayasari, Dhea Windhi Meilly Dwidasa Ekawati Merri Silvia Basri Moelyani, Endang Mohamad Fathoni Mohammad Alfian Muh Tawil, Muh Muhamad Alda Muhammad Adrian Fauzi Muhammad Ikhwan Rizki Munandar , Aris Munthe, Widhi Sofie Murti Andriastuti, Murti Naila Muqorriba Nainggolan, Lydia Irani Nancy Rahakbau Nanda Mauliditya, Dwi Nasution, Rini Octavia Niken Ulupi Ningsih, Sunarti Maili Ningsih, Wita Normaidah, Normaidah Novita, Vivin Nurdiana Nurhayati Nurhayati Nurhikmayanti, Kartika Nurhikmayanti Nurjayanti, Gita Nurkhasanah, Ayu Nurlindah Hamrun Nurniza, Nita Pintauli, Sondang Pitu Wulandari Pramesti Nurul Adinda Pratiwi, Asti Pria Rizqi Baihaqi Priatna Sari, Yeni Priatna, Yeni Prima Astuti Handayani Primardiana Hermilia Wijayati Puji Rahayu Purnamasari, Anisa Putri Puspita sari Putri, Anisa Ika Putri, Asyuni Ramadani, Nur Salsabillah Rayuna Handawati Riani, Siti Nur Riphaldi, Rizky Riska Royani Riski Candra Kharisma Ritawaty, Noor Romaulianna Theresia Marbun Rudi Afnan Rukmini Rumapea, Elina Lulu Ruqoyyah Fitri Safira, Occha putrie Salamatusshodri Salim, Supardi Salma, Atika Salsabilla, Deeva Putri Sam'aarif, Sam'aarif Samran, Samran Samsul Hadi Sanggam Siahaan Saputra, Ferdyan Wana Saragih, Sonia Ayunita Sari Theresia Bukit Sari, Annastasya Nurrahma Sari, Felia Novita Sari, Nilam Kencana Sarmila, Sarmila Sawani , Yussri Sayyidusy, Assagaf Sebayang, Loraetta Brety Sedya Utami, Erni Unggul Selviana, Indah Sidabutar, Herlina Sihombing, Ginna Veronica SILALAHI, TIODORA FERMISKA Silvani Tri Julianti Sitanggang, Anita Sitanggang, Maria NH Siti Asiyah Maulidia Siti Mufidah Siti Wahyuni Sitompul, Andelila Suprianti Sumardi . Suprianto Suprianto Suud, Mochammad Syafriani, Dini Syarifuddin, Shopian Tati Murni Karo Karo TB, Desita Ria Yusian Teguh Sabar Iman Tibrani, Mgs. Muhammad Trelia Boel, Trelia Triwibowo, Edi Umrah, St Veronica, Syndi Ayu Veronika, Maria Wafanjar, Wafanjar Wahidin Weni Maherna Wibiwo, Muhammad Editia Kharisma Wibiwo Wilda H. Lubis Windi Yahya, Adibah Yasmin, Arifia Yeni Kustiyahningsih Yeni Priatna Sari Yeni Priatna Sari, Yeni Priatna Yohani, Adisthi Martha Yurnilawati, Yurnilawati Yusuf, Albiri Zakiah Wulandari Zoraya, Amelia Zuhroh, Mimik Umi