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The Protective Effect of Solanum betaceum Extract on Spermatozoa Vitality Exposed to Lead Acetate in Mice Rima Wirenviona; Reny I’tishom; Siti Khaerunnisa
STRADA : Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v9i2.297

Abstract

The purpose of this study was to analyze the effect of giving various dosages of Solanum betaceum extract on the vitality spermatozoa mice exposed to lead acetate. This research was true experimental using randomized post-test only control group design. The total sample was 40 mice which were divided into 5 groups. Lead acetate used a dose of 75 mg/kg BW and various extracts of Solanum betaceum namely 100 mg/kg BW, 200 mg/kg BW and 400 mg/kg BW. Acclimatization was carried out for 7 days and continued with maintenance and treatment for 35 days. Statistical tests showed that there was a significant difference with (p=0.026). In conclusion, Solanum betaceum extract can be used as a protective to increase the vitality of spermatozoa exposed to lead acetate
The Effect of Comprehensive Sexual Education on Adolescent Behavior in Using Contraception : A Systematic Review Dzakiyyah, Nurul; I'tishom, Reny
Journal of Community Medicine and Public Health Research Vol. 6 No. 1 (2025): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v6i1.53684

Abstract

Adolescence is a transition period from childhood to adulthood. This period is crucial because there are many physical and psychological changes. One issue that is quite rife in Indonesia is teenage pregnancy, which will ultimately lead teenagers to have abortions. The case above proves that it is essential to equip adolescents with the knowledge and skills to make responsible choices. Comprehensive Sexual Education (CSE) is believed to help solve this problem and achieve the Sustainable Development Goals (SDGs) by 2030, when CSE also conveys the importance of contraception and its benefits. The lack of systematic reviews of studies that highlight the effect of implementing Comprehensive Sexual Education on current contraceptive use makes researchers interested in conducting this systematic literature review. This research uses a Systematic Literature Review (SLR) using PICO (Population, Intervention/Issue, Comparison/Context, Outcome), and Boolean operators are used to facilitate searching studies. PRISMA flowcharts were used in this research until two studies were included in the analysis. Literature quality assessment was conducted using the quality assessment tool for quantitative studies from EPHPP (Effective Public Health Practice Project). Two cross-sectional studies were based in the United States. The sample sizes in studies range from 5000 to 7000. The results of this study show that comprehensive sexual education influences the use of contraceptives today, although it is not very significant. However, there are still many biases in this research. There is a need to conduct randomized controlled trials or multicenter cohort studies that use the same evaluation parameters to strengthen future systematic review research.
New Paradigm of Gastric Pathogenesis: The Important Role of Gastric Microbiota Miftahussurur, Muhammad; Savitri, Camilia Metadea Aji; I'tishom, Reny; Rejeki, Purwo Sri; Rezkitha, Yudith Annisa Ayu; Yamaoka, Yoshio
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.874 KB) | DOI: 10.24871/231202262-66

Abstract

Microbiota was deemed essential as it involved in energy metabolism, nutrient absorption, intestinal immune system maturation, and pathogen protection. Gastrointestinal microbiome played essential roles in human body, such as immune response regulation, pathogen colonization, and few other diseases.  The relation between gastric microbiota and host were difficult to explore for years due to unculturable microbes. Stomach with its acid production was presumed to be sterile and unfavorable for bacterial growth until the discovery of Helicobacter pylori. It dominates the stomach as it was estimated to colonize almost 50% global population. H. pylori infection was linked to the development of chronic gastritis and recognized as a definite carcinogen. There was a probability that the alteration of gastric microbiota likely influenced gastric immunobiology and possible gastric diseases. Recent studies showed that five phyla consist of Firmicutes, Bacteroidetes, Actinobacteria, Fusobacteria and Proteobacteria have been discovered in stomach mucosa which might contribute to the pathological process. In addition, genera such as Lactobacillus, Escherichia-Shigella, Lachnospiraceae, Burkholderia and Nitrospirae were considered to have a role on gastric carcinogenesis.
Co-Authors A. Marlinata Abadiyah Zakiah Kustantina Abdurachman Abdurachman Addia Salsabila Ade Septiari Rahman Adha, Ahmad Zaidan Ni'am Abu Aditiawarman Aditiawarman, Aditiawarman Ahmad Basori Ahmad Ricardo Silalahi Ahmad Ricardo Silalahi Ahmad Ricardo Silalahi Alphania Rahniayu Ami Ashariati Anak Agung Istri Dalem Cinthya Riris Anak Agung Istri Dalem Cinthya Riris Anak Agung Renjani Kanya Kumari Andi Yasmin Wijaya Andri Rezano Anggi Dearni Silalahi Anggita Putri Samara Annas, Jimmy Yanuar Anny Setijo Rahaju, Anny Setijo Arif Rananda Arifa Mustika Arrasy Khawarizmi Ashon Sa’adi Aslama, Fathiy Zakaria Asmalinda, Wita Astri Dewayani Atmaja, Maxwell Aucky Hinting Ayik Rochyatul Jannah Ayik Rochyatul Jannah Azarine Ariqoh Arysanti Bahyshidqi Bambang Purwanto Budi Sutikno Caesariska Deswima Christian Christopher Sunnu Clara Alverina Daniel Widiyanto David Setyo Budi Diana, Alis Nur Dienanta, Savira Butsainah Dita Mega Utami Doddy M Soebadi Dwiki Noni Armyta Dzakiyyah, Nurul Ebnudesita, Faiza Rahma Eddy Bagus Wasito Era Fazira Etik Yuliarini Widodo Evy Wulandari Evy Wulandari Faiza Rahma Ebnudesita Faiza Rahma Ebnudesita Faizah Sugiarto Fedik Abdul Rantam Feranita Kumalasari Fitri Indah Pratiwi Fitria Nengsih Gadis Meinar Sari Gondo Mastutik Hamdani Lunardhi Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Hanna Tabita Hasianna Silitonga Hendy Hendarto HERAWATI, LILIK Hermina Novida, Hermina Heru Fajar Trianto Hudi Winarso Inda Corniawati Indra Alfaray, Ricky Intan Indah Permatasari IRWANTO Isnin Anang Marhana James Alfedo Jannah, Ayik Rochyatul Jefry Albari Tribowo Jihadna Prima Santika Ruslan Musanip Kartika Afrida Fauzia Kevin kevin Khaerunnisa, Siti Lionardy Yodianto Lukman Hakim Magfira Febrianty Lacindung Maria Magdalena Awi Mochamad Amin Mochammad Abdul Aziz, Mochammad Abdul Mohammad Anam Al-Ari Mohammad F. Qorib Mohammad Fathul Qorib Muhammad Miftahussurur Mustafa, Mohammad R. Nathania Nathania Nathania Nila Kurniasari Ninik Darsini Nurul Jannatul Wahidah Nurul Jannatul Wahidah Nurwasis Nurwasis Nyilo Purnami Purnama, Michael Purwanti, Dwi Puspitasari, Renny N. Qurnianingsih, Ema Rafida Anshori Raharjo, Rahmawati Rejeki, Purwo Sri Reryd Arindany Wiryawan, Reryd Arindany Ria Margiana Ria Margiana Rima Wirenviona Rima Wirenviona Rizaldi, Fikri Rize Budi Amalia Rizkiliano, Ibrahim Hanif Rochmah Kurnijasanti Rossy Sintya Marthasari S.Pd. M Kes I Ketut Sudiana . Safira Nur Izzah Salsabila Rahma Nurani Putri Salsabila, Unik Hanifah Sandra Dewi Sitaresmi Savira Butsainah Dienanta Savira Butsainah Dienanta Savitri, Camilia Metadea Aji Selvina Cindy Kusumaningrum Shahnaz Azzahra Siti Khaerunnisa Soebadi, Doddy Soetojo Sofia Zahra Kamila Sri A. Sudjarwo Sri Agus Sudjarwo Sri Purwaningsih Sri Ratna Dwiningsih Steven Sheng Looi Sudana, Nathan Kunta Sudjarwo, Sri A. Suhartono Taat Putra Sunaryo Hardjowijoto Supardi Supardi Susanti, Nurul Fatimah Suyono, Seso Sulijaya Syahnural Syahnural Syarifah, Anis Satus Tanojo, Tjahjo Djojo Tjahjo Djojo Tanojo Tjahjo Djojo Tanojo Tutus Rachkutho Vania Islamey Kusuma wahjoe djatisoesanto Wahyul Anis Widjayanti, Yhenti Widya Juwita WINARTO Winona May Hendrata Yassin, Tita Rudini Yaudiwati, Rina Yohana djurumana Yoshio Yamaoka, Yoshio Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Yudiwati, Rina Yuliawati, Tri Hartini Zuhria, Ismi