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New Paradigm of Gastric Pathogenesis: The Important Role of Gastric Microbiota Miftahussurur, Muhammad; Savitri, Camilia Metadea Aji; I'tishom, Reny; Rejeki, Purwo Sri; Rezkitha, Yudith Annisa Ayu; Yamaoka, Yoshio
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.874 KB) | DOI: 10.24871/231202262-66

Abstract

Microbiota was deemed essential as it involved in energy metabolism, nutrient absorption, intestinal immune system maturation, and pathogen protection. Gastrointestinal microbiome played essential roles in human body, such as immune response regulation, pathogen colonization, and few other diseases.  The relation between gastric microbiota and host were difficult to explore for years due to unculturable microbes. Stomach with its acid production was presumed to be sterile and unfavorable for bacterial growth until the discovery of Helicobacter pylori. It dominates the stomach as it was estimated to colonize almost 50% global population. H. pylori infection was linked to the development of chronic gastritis and recognized as a definite carcinogen. There was a probability that the alteration of gastric microbiota likely influenced gastric immunobiology and possible gastric diseases. Recent studies showed that five phyla consist of Firmicutes, Bacteroidetes, Actinobacteria, Fusobacteria and Proteobacteria have been discovered in stomach mucosa which might contribute to the pathological process. In addition, genera such as Lactobacillus, Escherichia-Shigella, Lachnospiraceae, Burkholderia and Nitrospirae were considered to have a role on gastric carcinogenesis.
Deteksi Dini Kanker Cerviks pada Pekerja Migran Indonesia di Malaysia Asmalinda, Wita; Widjayanti, Yhenti; I'tishom, Reny; Corniawati, Inda; Syahnural, Syahnural
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 10 (2024): Volume 7 No 10 (2024)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i10.16661

Abstract

ABSTRAK Kanker serviks diderita oleh hampir 1,4 juta wanita di seluruh dunia dan merupakan kanker reproduksi wanita terbanyak ke-2. Di Indonesia angka kejadian kanker serviks adalah  14,1 per 100.000 Tujuan pengabdian Masyarakat (PKM) Internasional meningkatkan pengetahuan dan kesadaran para pekerja migran Indonesia di Malaysia terhadap deteksi dini kanker serviks. Permasalahan yang dialami oleh para perempuan pekerja migran Indonesia (PMI) di Malaysia adalah tingkat pengetahuan dan kesadaran untuk melakukan deteksi dini kanker serviks masih rendah. Metode yang dilakukan adalah  edukasi dan skrining kanker serviks yang dilakukan dalam 3 tahap yaitu perencanaan, pelaksanaan dan evaluasi. Tahap perencanaan dengan melakukan koordinasi tim PKM yang terdiri atas doctor ilmu kedokteran, dokter spesialis obgyn,  bidan dan  perawat kesehatan reproduksi dan pihak mitra yaitu LSM Sharing, penyusunan media pembelajaran dan identifikasi kebutuhan belajar mitra PKM. Tahap pelaksanaan yaitu pemberian edukasi dan skrining dilakukan  hari minggu tanggal 27 Mei 2024 di Sekolah Indonesia Kuala Lumpur diikuti oleh 102 PMI yang berusia 14 – 63 tahun. Pemberian edukasi dilakukan dengan 2 metode yaitu konseling dan ceramah dengan menggunakan media power point dan e-booklet. Metode konseling dilakukan secara individu untuk 21 perempuan PMI yang teridentifikasi memiliki resiko tinggi untuk menderita kanker serviks. Edukasi dengan metode ceramah dilakukan untuk seluruh PMI. Hasil evaluasi menunjukkan peningkatan pengetahuan dan kesadaran perempuan PMI maupun keluarga tentang pentingnya deteksi dini kanker serviks.  Pihak KBRI diharapkan memfasilitasi layanan kesehatan untuk melakukan deteksi dini  kanker serviks baik berupa tes IVA maupun pap smear secara rutin minimal 1 tahun sekali bagi para pekerja yang telah berusia >15 tahun dan telah melakukan hubungan seksual. Kata Kunci: Deteksi Dini, Kanker Serviks, Kesehatan Reproduksi, Pekerja Migran  ABSTRACT  Cervical cancer affects nearly 1.4 million women worldwide and is the 2nd most common female reproductive cancer. In Indonesia, the incidence of cervical cancer is 14.1 per 100,000. The International Community Service aimed to increase the knowledge and awareness of Indonesian migrant workers in Malaysia regarding the early detection of cervical cancer. The problem experienced by female Indonesian migrant workers in Malaysia was that the level of knowledge and awareness regarding early detection of cervical cancer was still low. The method used was education and cervical cancer screening which was carried out in 3 stages, namely planning, implementation, and evaluation. The planning stage involved coordinating the International Community Service team consisting of a doctor of medical science, an ob-gyn specialist, midwives,   a reproductive health nurse, and Non-Government organizations of Sharing, preparing learning media, and identifying the learning needs of International Community Service partners. The implementation stage, namely providing education and screening, was carried out on Sunday 27 May 2024 at the Kuala Lumpur Indonesian School, attended by 102 Indonesian migrant workers aged 14 - 63. Providing education was carried out using 2 methods, namely counseling and lectures using PowerPoint and e-booklet media. The counseling method was carried out individually for 21 female Indonesian migrant workers who were identified as having a high risk of suffering from cervical cancer. Education using the lecture method was conducted for female Indonesian migrant workers and their families. The evaluation results showed an increase in knowledge and awareness of female Indonesian migrant workers and their families about the importance of early detection of cervical cancer. The Indonesian Embassy is expected to facilitate health services to carry out early detection of cervical cancer in the form of VIA tests and regular Pap smears at least once a year for workers who are >15 years old and have had sexual relations.. Keyword: Early Detection, Cervical Cancer, Reproductive Health, Migrant Worker
PEMBERDAYAAN KADER KESEHATAN REPRODUKSI MELALUI PEMERIKSAAN MIKROPENIS DAN HIPOSPADIA SISWA SDN MODEL BANYUWANGI KABUPATEN BANYUWANGI I'tishom, Reny; Agustinus, Agustinus; Rezkiawan, Ditto; Indarto Susilo, Rahadian; Syahrizal Pasaribu, Wanly; Lionardi, Samuel; Putri Handini, Lika; Melka Parmanto, Cristian; Susanto, Natasha; Maulana Ishom Putra, Wildan; Setiono, Budi
Jurnal Abdi Insani Vol 11 No 2 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i2.1587

Abstract

Cases of micropenis and hypospadias are like the tip of the iceberg, as many parents are yet to identify and be aware enough to have their child's abnormalities checked by a doctor. Micropenis and hypospadias abnormalities can be well managed if detected before puberty, but parents' long-term ignorance can lead to infertility, malignancy, and urinary dysfunction in their children. Education aims to increase parents' knowledge and awareness to detect genital abnormalities in boys, so they can be addressed as early as possible. So far, there is no data on micropenis cases, hypospadias cases, or the average penis length in elementary school students, thus genital examinations in elementary school students are crucial for screening and obtaining accurate data. Activity Method: Parents and teachers will be asked to take a pre-test, then attend education sessions on micropenis and hypospadias, followed by discussions and Q&A sessions. A post-test will be conducted to test the participants' understanding of the education. Participants who agree for their sons to undergo physical and genital examinations will be examined in the school health unit (UKS). Results: A total of 39 male students participated with an average age of 10.77 ± 1.05 years. Cases of phimosis were found in 3 individuals, buried penis in 5 individuals, high-placed testes in 2 individuals, and varicocele in 1 individual. No cases of micropenis or hypospadias were found. The average penis length was 6.76 ± 1.78 cm, the right testis volume was 4.10 ± 2.10 ml, and the left testis volume was 4.13 ± 2.19 ml. Conclusion: Although no cases of micropenis and hypospadias were found in students, other genital abnormalities such as phimosis, buried penis, high-placed testes, and varicocele were detected.
Co-Authors A. Marlinata Abadiyah Zakiah Kustantina Abdurachman Abdurachman Addia Salsabila Ade Septiari Rahman Adha, Ahmad Zaidan Ni'am Abu Aditiawarman Aditiawarman, Aditiawarman Agustinus Agustinus Ahmad Basori Ahmad Ricardo Silalahi Ahmad Ricardo Silalahi Ahmad Ricardo Silalahi Alphania Rahniayu Ami Ashariati Anak Agung Istri Dalem Cinthya Riris Anak Agung Istri Dalem Cinthya Riris Anak Agung Renjani Kanya Kumari Andi Yasmin Wijaya Andri Rezano Anggi Dearni Silalahi Annas, Jimmy Yanuar Anny Setijo Rahaju, Anny Setijo Arif Rananda Arifa Mustika Arrasy Khawarizmi Ashon Sa’adi Aslama, Fathiy Zakaria Asmalinda, Wita Astri Dewayani Atmaja, Maxwell Aucky Hinting Ayik Rochyatul Jannah Ayik Rochyatul Jannah Azarine Ariqoh Arysanti Bahyshidqi Bambang Purwanto Caesariska Deswima Christian Christopher Sunnu Clara Alverina Daniel Widiyanto David Setyo Budi Diana, Alis Nur Dienanta, Savira Butsainah Dita Mega Utami Ditto Rezkiawan Doddy M Soebadi Dwiki Noni Armyta Dzakiyyah, Nurul Ebnudesita, Faiza Rahma Eddy Bagus Wasito Era Fazira Etik Yuliarini Widodo Evy Wulandari Evy Wulandari Faiza Rahma Ebnudesita Faiza Rahma Ebnudesita Faizah Sugiarto Fedik Abdul Rantam Feranita Kumalasari Fitri Indah Pratiwi Fitria Nengsih Gondo Mastutik Hamdani Lunardhi Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Hanna Tabita Hasianna Silitonga Hendy Hendarto HERAWATI, LILIK Hermina Novida, Hermina Heru Fajar Trianto Hudi Winarso Inda Corniawati Indarto Susilo, Rahadian Indra Alfaray, Ricky Intan Indah Permatasari IRWANTO Isnin Anang Marhana James Alfedo Jannah, Ayik Rochyatul Jefry Albari Tribowo Jihadna Prima Santika Ruslan Musanip Kartika Afrida Fauzia Kevin kevin Khaerunnisa, Siti Lionardi, Samuel Lionardy Yodianto Lukman Hakim Magfira Febrianty Lacindung Maria Magdalena Awi Maulana Ishom Putra, Wildan Melka Parmanto, Cristian Mochamad Amin Mochammad Abdul Aziz, Mochammad Abdul Mohammad Anam Al-Ari Mohammad F. Qorib Mohammad Fathul Qorib Muhammad Miftahussurur Mustafa, Mohammad R. Nathania Nathania Nathania Nila Kurniasari Ninik Darsini Nurul Jannatul Wahidah Nurul Jannatul Wahidah Nurwasis Nurwasis Nyilo Purnami Purnama, Michael Purwanti, Dwi Puspitasari, Renny N. Putri Handini, Lika Qurnianingsih, Ema Raden Mohamad Herdian Bhakti Rafida Anshori Raharjo, Rahmawati Rejeki, Purwo Sri Reryd Arindany Wiryawan, Reryd Arindany Ria Margiana Ria Margiana Rima Wirenviona Rima Wirenviona RINA YUDIWATI BM, RINA Rizaldi, Fikri Rize Budi Amalia Rizkiliano, Ibrahim Hanif Rochmah Kurnijasanti Rossy Sintya Marthasari S.Pd. M Kes I Ketut Sudiana . Safira Nur Izzah Salsabila Rahma Nurani Putri Salsabila, Unik Hanifah Sandra Dewi Sitaresmi Sari, Gadis Meinar Savira Butsainah Dienanta Savira Butsainah Dienanta Savitri, Camilia Metadea Aji Selvina Cindy Kusumaningrum Setiono, Budi Shahnaz Azzahra Siti Khaerunnisa Soebadi, Doddy Soetojo Soetojo Sofia Zahra Kamila Sri A. Sudjarwo Sri Agus Sudjarwo Sri Ratna Dwiningsih Steven Sheng Looi Sudana, Nathan Kunta Sudjarwo, Sri A. Suhartono Taat Putra Sunaryo Hardjowijoto Supardi Supardi Susanti, Nurul Fatimah Susanto, Natasha Suyono, Seso Sulijaya Syahnural, Syahnural Syahrizal Pasaribu, Wanly Syarifah, Anis Satus Tanojo, Tjahjo Djojo Tjahjo Djojo Tanojo Tjahjo Djojo Tanojo Tutus Rachkutho Vania Islamey Kusuma wahjoe djatisoesanto Wahyul Anis Widjayanti, Yhenti Widya Juwita WINARTO Winona May Hendrata Yassin, Tita Rudini Yaudiwati, Rina Yohana djurumana Yoshio Yamaoka, Yoshio Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Yuliawati, Tri Hartini Zuhria, Ismi