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All Journal JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Jurnal Surya Medika Bunda Edu-Midwifery Journal (BEMJ) Journal of Midwifery and Nursing Jurnal Jamu Indonesia Reswara: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Medicamento Indonesia Berdaya Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal Of Human And Education (JAHE) Journal of Pharmaceutical Care and Sciences Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA) SENTRI: Jurnal Riset Ilmiah Journal of Artificial Intelligence and Digital Business Innovative: Journal Of Social Science Research Sains Medisina Health Research Journal of Indonesia Journal of Advances in Medicine and Pharmaceutical Sciences Promotor: Jurnal Mahasiswa Kesehatan Masyarakat Jurnal Farmasi SYIFA Health Sciences International Journal Juragan (Jurnal Agroteknologi) JFARM (Jurnal Farmasi) NU-JST Indonesian Journal of Jamu KBJPM- Kayuh Baimbai Jurnal pengabdian masyarakat
Nastiti, Kunti
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A Aktivitas Antibakteri Ekstrak Daun Kopi Aranio (Coffea canephora ) Terhadap Bakteri Propionibacterium Acnes: Aktivitas Antibakteri Ekstrak Daun Kopi Aranio (Coffea canephora ) Terhadap Bakteri Propionibacterium Acnes Rahmah, Aulia; Nastiti, Kunti; Mahdiyah, Dede; Darsono, Putri Vidiasari
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.417

Abstract

Background: Acne is a skin disease due to chronic inflammation with complex pathogenesis, excessive bacterial colonization, and inflammation. One of the causes of acne is due to excessive sebum gland activity and is exacerbated by bacterial infection, one of the bacteria that causes acne is Propionibacterium acnes. Coffee leaves are used by the community, especially in Babayau Village, Balangan Regency, South Kalimantan, to treat acne naturally and traditionally by mixing the cleaned coffee leaves with wet powder and then rubbing it evenly all over the face.         Objective: Knowing the effectiveness of coffee leaf extract (Coffea canephora) in inhibiting the growth of Propionibacterium acnes bacteria, and knowing the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration against Propionibacterium acnes bacteria.                                              Methods: The type of research to test the antibacterial activity of aranio coffee leaf extract against Propionibacterium acnes bacteria was true expertimental with a post test only control group design, control group 100%, 75%, 50% and 25%, negative control using DMSO, positive control with clindamycin. Screening for antibacterial activity of aranio coffee leaf extract using the disc diffusion method and determining the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration using the dilution method.                                                                Results: Coffee leaf extract (Coffea canphora) contains secondary metabolites, namely flavonoids, tannins, and saponins which have antibacterial activity. The antibacterial activity test of coffee leaf extract (Coffea canphora) in the disc diffusion method had an inhibition zone of 27.86 ± 2.14 while in the dilution method the Minimum Inhibitory Concentration (MIC) was at a concentration of 75% and did not have a Minimum Bactericidal Concentration (MBC).                                                Conclusion: Coffee leaf extract (Coffea canphora) can inhibit Propionibacterium acnes at a concentration of 75%, and cannot kill Propionibacterium acnes.                                               
P Profil Senyawa Alkaloid Dengan Metode Spektroskopi Inframerah (FTIR) Dan Penetapan Kadar Total Alkaloid Dari Ekstrak Daun Jarak Pagar (Jatropha curcas .L) Gamah, Gamah; Nastiti, Kunti; Aryzki, Saftia
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.476

Abstract

Background: Jatropha curcas leaves (Jarropha Curcas L.) is a plant that has potential medicinal properties. Empirically, Jatropha leaves (Jarropha Curcas L.) are used by the people of South Kalimantan to expedite the delivery process. One of the compounds that have pharmacological properties in Jatropha curcas leaves is alkaloids. Objective: Knowing the alkaloid compounds using infrared spectroscopy (FTIR) and determining the total alkaloid content of jatropha leaf extract (Jatropha Curcas L) leaf extract. Methods: This study used descriptive qualitative analysis to identify alkaloid functional groups from FTIR results and quantitative analysis to determine total alkaloid content. Results: Preliminary test results using thin layer chromatography on Jatropha curcas leaves (Jatropha Curcas.L) were positive for containing alkaloid compounds. The FTIR results showed that there was an alkaloid compound content in the presence of functional groups which were obtained C-H, C=O, C-O, N-H and aromatic C-H which are characteristics of alkaloid compounds and the total alkaloid content was obtained 5,645 % (g/5g). Conclusion: Jatropha curcas leaf extract (Jatropha curcas L) using FTIR analysis showed the content of alkaloid compounds and the total alkaloid content obtained was 5,645 % (g/5g).    
E Etnomedicine Tumbuhan Obat di Masyarakat Desa Belangian, Kalimantan Selatan: Syahfitri, Laili Shinta Ayu; Nastiti, Kunti; Kurniawati, Darini; Rohama, Rohama
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 2 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i2.549

Abstract

Background: The diversity of tribes and cultures in Indonesia makes culturaldifferences and traditional knowledge, one of which is in utilizing plants for thetreatment of a disease. One of the widespread tribes on the island of Kalimantanthat is thick with traditional medicine is the Banjar Tribe located in BelangianVillage, South Kalimantan. Ethnomedisin is a treatment by certain ethnicities basedon hereditary traditions in traditional medicine, in this case the use of medicinalplants.Objective: The purpose of this study was to determine the ethnomedicine ofmedicinal plants used by the Banjar Tribe of Belangian Village, Aranio District,South Kalimantan Province.Methods: This research is descriptive using qualitative and quantitative methods.Quantitative analysis with Fidelity Level (FL) calculations for each type ofmedicinal plant.Result: Based on the results of research from 38 informants, 58 species with 36families were obtained. There are 50 diseases that can be treated from 58 types ofmedicinal plants. The most popular method of processing is boiled 56.89 then drunk72.41%. The most widely used part of medicinal plants is the leaf part of 41.73%.Five types of plants with the highest FL values that stated effectiveness for treatmentwere Cymbopogon citratus 86.84%, Zingiber officinale 78.94%, Jatropha multifidaL 73.64%, Peronema canescens jack 68.42%, Syzygium polyanthum 65.78%. Thetradition of treatment with medicinal plants by the Banjar Tribe has been passeddown for generations with the value of local wisdom in its use.Conclusion: There are 58 types of medicinal plants that can be used as medicineor relief for certain diseases by the people of the Banjar Tribe, Belangian Village.With the highest FL value of five is found in Cymbopogon citratus plants 86.84%,Zingiber officinale 78.94%, Jatropha multifida L 73.64%, Peronema canescensjack 68.42%, Syzygium polyanthum 65.78%.
M Monitoring Efek Samping Obat Antihipertensi Di Puskesmas Kertak Hanyar Kabupaten Banjar Trisia, Trisia; Kurniawati, Darini; Nastiti, Kunti; Aryzki, Saftia
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.720

Abstract

Background: Hypertension is a condition where blood pressure increases from normal or reaches 140/90 mmHg. In Indonesia, the prevalence of hypertension has increased, especially in South Kalimantan. The use of antihypertensive drugs is necessary to control blood pressure and is used long term, but it often causes side effects that can affect the patient's quality of life. So it is necessary to monitor drug side effects to monitor unwanted reactions after administering the drug. Objective: To identify the characteristics of patients who experience side effects and identify the incidence of side effects of antihypertensive drugs. Methods: The method used in this research is descriptive observational with a cross sectional design, and the sampling technique uses purposive sampling technique. The data collection instrument uses an observational sheet. Results: Based on the research results, it shows that the majority of respondents were aged 56-65 years (36.08%), female (55.70%), had elementary school education (36.72%) and worked as farmers (36.70%). The most widely used antihypertensive drug was single Captopril (44.30%) and there were 110 respondents (69.62%) who experienced drug side effects in the form of dry cough (47.27), swelling (23.63%), dizziness (16 .36%) and itching (12.72%). Conclusion: Based on the results of research conducted on 158 respondents, 110 reported experiencing drug side effects. The most commonly reported side effects are dry cough, swelling, dizziness and itching
U Uji Aktivitas Antibakteri Jamur Endofit Batang Bajakah Tampala (Spatholobus Littoralis Hassk) Pada Bakteri Salmonella Typhi Elysa, Elysa; Chandra, M. Andi; Nastiti, Kunti
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.735

Abstract

Bajakah Tampala is often used by the people of Halong District Village for wisa disease or high fever which is believed to be typoid by boiling the bark of Bajakah Tampala (Spatholobus littoralis Hassk) wood. The use of traditional medicine from plants that are abundant in nature. This endophyte is research in the field of biotechnology using small samples from the original plant to obtain the same compounds as the original plant so that biodiversity is maintained. The aim of this research is to determine the type of endophytic fungi produced by Bajakah Tampala stem (Spatholobus Littoralis Hassk) and the greatest antibacterial activity of the endophytic fungi produced by Bajakah Tampala stem (Spatholobus Littoralis Hassk) using the diffusion method and to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) against Salmonella typhi bacteria, the research method stage involves growing endophytic fungi, isolated and separated according to the type of fungus, followed by testing on Salmonella typhi bacteria. The greatest antibacterial activity was then determined by MIC and MBC by making various concentrations, and the positive control was chloramphenicol. The research found three types of endophyte isolates, Bajakah Endophyte Isolate 1 (IEB1), Bajakah Endophyte Isolate 2 (IEB2), Bajakah Endophyte Isolate 3 (IEB3), the results showed the largest potential inhibition zone in the IEB3 isolate was 28.78 mm compared to the antibiotic chloramphenicol with an inhibition zone of 24.42 mm. MIC testing shows the level of turbidity at a concentration of 6.25% and has a MBC that counts the number of colonies at a concentration of 25%. the result of the endophytic fungus Bajakah Tampala stem Spatholobus Littoralis Hassk) which has antibacterial activity and the ability to kill Salmonella typh bacteria
Gula Tebu (Saccharum Officinarum Linn.) dan Palam (Arenga Pinnata Merr.) Terhadap Diabetes Samsul Hadi; Nastiti, Kunti
JFARM - Jurnal Farmasi Vol. 2 No. 1 (2024)
Publisher : Yayasan Rahmatan Fiddunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jfarm.v2i1.624

Abstract

Gula merupakan kebutuhan pokok manusia. Tingkat konsumsi didunia semakian meningkat seiring dengan prkembangan jaman dan pertumbuhan ekonomi. Gula di indonesia dibagi menjad dua yaitu gula tebu dan gula merah yang mempunyai pengaruh terhadap terjadinya diabetes. Tujuan dari review ini adalah mengetahui informasi menganai kandungan gula tebu dan merah pada terjadinya diabetes. Berdasarkan pencarian artikel pada berbagai publikasi diperoleh hasil kandungan kualitatif gula tebu dan gula merah tidak berbeda. Yang membedakan adalah kadar kanduangan secara kuntitatif antara gula tebu dan gula merah. Gula merah mengandung molase lebih sedikit dibandingkan gula tebu, sehingga secara signifikan membuatnya lebih sehat atau memiliki risiko diabetes yang lebih rendah.
Prediksi Toksisitas Ginjal Cabe Jawa (Piper Retrofractum Vahl.) Dengan Metode In Silico Samsul Hadi; Setiawan, Deni; Rahmadina, Nazwa; Ramadani, Rizka Aulia; Nastiti, Kunti
JFARM - Jurnal Farmasi Vol. 2 No. 2 (2024)
Publisher : Yayasan Rahmatan Fiddunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jfarm.v2i2.1022

Abstract

Cabe Jawa (Piper retrofractum Vahl.) dikenal sebagai bahan baku pembuatan dalam herbal. Dengan manfaat yang begitu luas, diperlukan penelitian mengenai toksisitas P. retrofractum khususnya terhadap ginjal. Tujuan dari penelitian ini adalah melakukan skrining senyawa kimia dari P. retrofractum yang berpotenssi menyebabkan gangguan ginjal. Metode yang digunakan dalam penelitian ini adalah menggunakan docking PLANTS dan bahan yang digunakan dalam penelitian ini diperoleh darai knapsackfamily. Hasil dari penelitian ini diperoleh skore docking masing masing ligand sebagai berikut (+)-Sesamin (-83.8785); L-Sesamin (-85.9199); Guineensine (-104.444); Pipercide (-95.8947); Retrofractamide A (-92.7619); Methyl piperate (-75.2266); 3, 4, 5-Trimethoxy dihydrocinnamic acid (-43.388).  Kesimpulan penelitian ini adalah senyawa yang berpotensi dari P.retrofractum yang berpotensi menyebabkan gangguan ginjal adalah Guineensine.
Konsentrasi Hambat Minimal (KHM) dan Konsentrasi Bunuh Minimal (KBM) Jamur Endofit Bajakah (Spatholobus Littoralis Hassk) Pada Escherichia Coli Fatimah, Siti; Nastiti, Kunti; Hastika, Febby Yulia; Darsono, Putri Vidiasari
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 4 No. 4 (2026): November - January
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v4i4.4233

Abstract

Jamur endofit yang diisolasi dari tanaman inangnya diketahui mampu menghasilkan senyawa metabolit sekunder yang memiliki kesamaan struktur maupun fungsi dengan senyawa yang diproduksi oleh tanaman tersebut. Keunggulan ini membuat jamur endofit menjadi sumber alternatif yang sangat potensial dalam penyediaan senyawa bioaktif tanpa harus melakukan ekstraksi langsung dari tanaman. Pendekatan ini tidak hanya mengurangi eksploitasi tanaman obat, seperti bajakah (Spatholobus littoralis Hassk), tetapi juga mendukung upaya pelestarian keanekaragaman hayati yang semakin terancam oleh meningkatnya kebutuhan bahan baku herbal. Penelitian ini dilakukan untuk mengetahui kemampuan aktivitas antibakteri jamur endofit dalam menghambat dan membunuh bakteri Escherichia coli serta mengidentifikasi jenis jamur endofit berdasarkan karakteristik makroskopis dan mikroskopisnya. Metode penelitian yang digunakan adalah True Experimental, meliputi uji zona hambat menggunakan cakram untuk melihat kemampuan penghambatan, serta uji KHM (Konsentrasi Hambat Minimum) dan uji KBM (Konsentrasi Bunuh Minimum) untuk menentukan efektivitas konsentrasi ekstrak jamur. Hasil penelitian menunjukkan bahwa seluruh isolat jamur endofit memiliki aktivitas antibakteri dengan kategori kuat. Isolat JEB 1 yang berwarna hitam menunjukkan hasil paling signifikan dengan zona hambat sebesar 16,20 mm. Nilai KHM isolat tersebut berada pada konsentrasi 4 × 10⁵ ppm, sedangkan nilai KBM berada pada konsentrasi yang sama dengan jumlah koloni <300. Kondisi ini menegaskan bahwa isolat JEB 1 bersifat bakteriostatik sekaligus bakterisidal terhadap E. coli. Dengan demikian, jamur endofit batang bajakah, terutama isolat JEB 1, berpotensi besar dikembangkan sebagai agen antibakteri alami yang efektif dan berkelanjutan
Co-Authors Adi Rahmadi Adriana Palimbo, Adriana Agustin, Nur Syafa Alfisah, Firda Alfisyah, Nur Ali Rakhman Hakim Angelica , Viona Febriola Anggraini, Novita Yeremia Aryzki, Saftia Aulia Rahmah Aulia Ramadani, Rizka Bariroh, Laili Carolina, Feliya Chandra, M. Andi Chintia, Avrensya Eka Daifa, Tri Masruratun Damayanti, Linda Meydigret Dede Mahdiyah, Dede Deni Setiawan DENI SETIAWAN Deny Setiawan Deviani, Norma DWI RAHMAWATI Dwi Salmarini, Desilestia Effendi, Budi Yanto Elvine Ivana Kabuhung Elysa, Elysa Ermadiningtyas, Retno Erpiana, Indah Nor Farhiya, Naila Fatimah Azzahra Fatmala, Ella Mauli Fatmalika, Tria Fitriani, Noor Gabriella, Maria Gamah, Gamah Gresiasiska, Sofia Gusnianti, Elva Habibah, Nor Hadi, Samsul Samsul Hariyadi, Ricky Hastika, Febby Yulia Hastika, Febby Yulika Hepriana, Yemima Hermawan, Afreza Rizky Husnati, Lailan Ika Friscila, Ika Ikeh, Tri Sulapmi D. Intan Intan Khatimah, Indah Husnul Kristiani, Windilla Kurniawati, Darini L. Lisnawati Lisaura, Inggrit Windy Lydia T, Ni Gitta Putri Ma'rifah, Nurul Maharani, Tri Anita Malahayati, Siti Maria Fransiska Mayasari, Vita Melviani, Melviani Mia Audina, Mia Muhammad Zulfadhilah Nathalia, Ayu Ningsih, Gusria Surya Noor Latifah Norpalah, Norpalah Noval Noval Noval Noval, N Novia, N Novianty, Nadya Nugraha, Dyan Fitri Nur Hidayah NURUL HIDAYAH Palianti, Zahra Putra, Dedy Karmadi Putri Vidiasari Darsono, Putri Vidiasari Putri, Trias Sofia Rahayu, Desi Dwi Rahayu, Eria Wienty Rahimah, Asri Rahimah, Rahimah Rahmadani Rahmadani Rahmadina, Nazwa Ramadani, Rizka aulia Rina Saputri Rizali, Muhammad Rizantha, M. Iqbal Rochaida, Try Rohama, Rohama Samsul Hadi Samsul Hadi Samsul Hadi Saniah, Husnus Saputri, Nur Arida Sari, Eliza Karmila SARKIAH SARKIAH Sary, Ariska Yulia Setia Budi Siti Fatimah Siti Khadijah Sukmana, M. Laily Qadry Surya Rinjani, Lalu Erwin Tri Syahfitri, Laili Shinta Ayu Syahrina, Dahlia Trisia, Trisia Tuti Alawiyah Ulfah, Annisa Widianto, Argo Wilujeng, Wilujeng Wulandari, Suci Sri Yuwindry, Iwan