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All Journal Jurnal Gizi dan Pangan Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Jurnal Riset Kimia Journal of Agromedicine and Medical Sciences Jurnal Penelitian Kesehatan Suara Forikes Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Ilmiah Universitas Batanghari Jambi JURNAL KESEHATAN PERINTIS Majalah Kedokteran Andalas Jurnal Biomedika dan Kesehatan Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Nusantara Hasana Journal Jurnal EduHealth Jurnal Ilmu Kesehatan Indonesia (JIKSI) Andalas Dental Journal Sciences of Pharmacy Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Jurnal Riset Ilmiah Jurnal Sains Farmasi dan Kesehatan Jurnal Sains, Teknologi dan Kesehatan
Almurdi Almurdi
Andalas University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal EduHealth

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Bacterial Patterns and Sensitivity to Antibiotics in Neonatorum Sepsis Patients at Dr. M. Djamil Padang General Hospital in the Period 2018–2021 Fenty Primadhani; Linosefa, Linosefa; Fitrisia Amelin; Almurdi, Almurdi; Elly Usman; Rahmi Lestari
Jurnal EduHealth Vol. 16 No. 02 (2025): Jurnal EduHealt, Edition April - June , 2025
Publisher : Sean Institute

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Abstract

Neonatal sepsis is one of the leading causes of morbidity and mortality in neonates. Bacteria are the most common cause of neonatal sepsis. The appropriate empirical therapy is given based on the bacterial pattern and sensitivity at the site. The appropriate use of empirical antibiotics can help reduce the neonatal mortality rate. This study aimed to evaluate bacterial patterns and antibiotic sensitivity in neonatal sepsis patients at RSUP Dr. M. Djamil Padang period 2018-2021. This study is a descriptive study that used a total sampling method with 63 samples that met the inclusion criteria. The results showed that neonatal sepsis was most commonly found in neonates aged 4-28 days, which were mostly male, had a birth weight < 2500 grams, had a mortality rate of 25.4%, and neonatal pneumonia was the most comorbid disease. The most common causative bacteria were Klebsiella pneumoniae and Staphylococcus haemolyticus. Klebsiella pneumoniae is sensitive to amikacin, tigecycline, meropenem, and ertapenem. Staphylococcus haemolyticus was sensitive to tigecycline, nitrofurantoin, vancomycin, linezolid, and quinupristin / dalfopristin. This study concluded that the most common bacteria causing neonatal sepsis were Klebsiella pneumoniae and Staphylococcus haemolyticus. Klebsiella pneumoniae was sensitive to amikacin, tigecycline, meropenem, and ertapenem. Staphylococcus haemolyticus was sensitive to tigecycline, nitrofurantoin, vancomycin, linezolid, and quinupristin / dalfopristin. Clinicians are expected to review the clinical practice guidelines for neonatal sepsis to suit bacterial patterns and their sensitivity to antibiotics.
Co-Authors Adrial Adrial Afriani, Nita Alan Mustaqim Amelin, Fitrisia Annita Annita Annita, Annita Ansori, Fachrurrazi Al Arizal, Chairani Ashal, Taufik Asterina Asterina Aswiyanti Asri Aswiyanti Asri Azzati, Normaida Baizura Bobby Indra Utama Citra Manela Cut Mutiara Sabrina Dessy Arisanti Dessy Arisanti Dia Rofinda, Zelly Dia Dian Eka Putri, Dian Eka Dian Pertiwi Dian Pertiwi Dian Puspita Djong Hon Tjong Dwi Yulia Dwitya Elvira, Dwitya Efrida Efrida Efrida Eka Nofita Elly Usman Ellyza Nasrul Elmatris Sy Endrinaldi Endrinaldi Endrinaldi Erika, Niken Ayu Putri Erly Erly Febriyanti, Rizka Fenty Primadhani Frizki Amalya Putri Gita Rahmadani Gusti Revilla Gusti Revilla Hasmiwati Hendra Permana Hendriati, Hendriati Herman, Deddy Hirowati Ali Hirowati Ali, Hirowati Husnil Kadri Ida Rahmah Burhan Inayah Afrilina Isnindiah Koerniati Istiya Putri Lestari Julizar Julizar Julizar Nazar Khairunnisa, Ainindia Kosno Suprianto Laila Isrona Lili Irawati Linosefa Linosefa Lydia Susanti, Lydia M Ikhsan Mahata, Liganda Endo Malinda Meinapuri Mashoed, Meyfiana Aisyah Mega Ade Nugrahmi Meri Wulandari Millah Fithriyah Zindany Mohamad Reza Mohamad Reza Muhammad Iqballisandi Nabila, Fathiya Sarah Netti Suharti Noverial, Noverial Nur Afrainin Syah Nur Indrawati Lipoeto Nur Indrawati Lipoeto Nuzulia Irawati Rahmadina, Rahmadina Rahmadina, Rahmadina Rahman, Rifna Alya Rahmayana Rahmayana Rahmi Lestari Raissa Febrina Ramadhani, Melati Nurul Rauza Sukma Rita Restu Susanti Rifka Rahmat Rikarni Rikarni Rinal Effendi Rinang Mariko, Rinang Rismawati Yaswir Rita Permatasari Russilawati, Russilawati Rustini , Rini Ryri Rahmawati Helmi Saldi, Aisyah Afiah Izzaty Salsabilah Firdausiah Saptino Miro Saptino Miro, Saptino Silfina Indriani Sitti Monica Astrilia Ambon Sofitri Sofitri Sri Indrayati Sukri Rahman Syahrul , Muhammad Zulfadli Syandrez Prima Putra Ulya Uti Fasrini Utami, Putra Rahmadea Vitresia , Havriza Wendy Syafutra Yaslinda Yaunin Yulia, Dwi Yuliarni Syafrita Yulistini, Yulistini Yusri, Elfira YUSTI SIANA Yustini Alioes Zelly Dia Rofinda Zhuhra, Rahma Tsania