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All Journal Indonesian Journal of Cancer Chemoprevention Journal of Mathematical and Fundamental Sciences Indonesian Journal of Tropical and Infectious Disease JPM17: Jurnal Pengabdian Masyarakat UNEJ e-Proceeding Berkala Kedokteran JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Science and Technology Indonesia Panrita Abdi - Jurnal Pengabdian pada Masyarakat Universa Medicina ALCHEMY Jurnal Penelitian Kimia JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Kreativitas PKM PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Abdi: Media Pengabdian Kepada Masyarakat Journal of halal product and research (JHPR) Humanism : Jurnal Pengabdian Masyarakat Berkala Ilmiah Kimia Farmasi Tri Dharma Mandiri: Diseminasi dan Hilirisasi Riset Kepada Masyarakat (Jurnal Pengabdian Kepada Masyarakat) Pharmaceutical Sciences and Research (PSR) Jurnal Bakti Untuk Negeri Riset Informasi Kesehatan Camellia
Juni Ekowati
Departemen Ilmu Kefarmasian, Fakultas Farmasi, Universitas Airlangga
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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In silico Study on Physicochemical, Pharmacokinetic and Toxicity Profiles of Available Antiviral Drugs and The Drug-Target Interaction with Protease of SARS-CoV-2 Diyah, Nuzul Wahyuning; Ghifari, Aileen Syifa; Hidayati, Shabrina Wahyu; Ekowati, Juni
Camellia : Clinical, Pharmaceutical, Analytical and Pharmacy Community Journal Vol 1 No 2 (2022): Camellia (Clinical, Pharmaceutical, Analytical, and Pharmacy Community Journal)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/cam.v1i2.16714

Abstract

Introduction: In emergency conditions such as the COVID-19 pandemic, many drugs treating SARS-CoV-2 are currently being developed through the concept of repurposing the existing drugs. This study aims to evaluate the physicochemical, pharmacokinetic and toxicity (ADMET) profiles of 15 drugs that have been used clinically for other viral diseases, and inspect their activity as antivirals against SARS-CoV-2. Methods: The physicochemical properties were obtained by using the ChemDraw and the ADMET were predicted using pkCSM on line tools. The selected drugs based on Lipinski's Rules were docked into main protease of SARS-CoV-2 (PDB. 6LU7) using Molegro program. Results: Six drugs complied with Lipinski's Rules and showed good ADMET profile except for their hepatotoxicity, but favipiravir and oseltamivir were predicted to be non-hepatotoxic. Oseltamivir also showed high binding affinity with free energy score below -100 kcal/mol. Conclusions: Oseltamivir is a potential antivirus for COVID-19 based on physicochemical, ADMET profile, and in silico activity against protease of SARS-CoV-2. 
Activity of Alginate-Gelatin Hydrogels Containing Metal-Organic Frameworks Against Escherichia coli and Staphylococcus aureus for Wound Dressing Application Mulyati, Tri Ana; Ekowati, Juni; Sariwati, Atmira; Agustina, Lia; Wardani, Siska; Erawati, Erawati; Pujiono, Fery
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 3 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i3.77403

Abstract

Bacterial infections, such as S. aureus and E. coli, remain a global health issue, particularly concerning bacterial resistance, which often leads to serious complications. One approach to address this problem is the development of Metal Organic Frameworks (MOFs), known for their high conductivity and antibacterial activity. Zn-based MOFs are known to possess strong antibacterial activity because Zn²⁺ ions can damage bacterial cell membranes, disrupt enzymatic processes, and induce oxidative stress. In comparison, Zr-based MOFs are well known for their excellent chemical stability and biocompatibility. In this study, hydrogels containing three types of MOFs-Zn-BDC, Zn-Fer, and Zr-BDC were developed. This research aims to synthesize and characterize alginate-gelatin hydrogels containing MOFs and evaluate their antibacterial activity. The results indicate that the modification of alginate-gelatin hydrogels with MOFs has been successfully synthesized, as evidenced by FTIR, XRD, and SEM-EDS analyses. The materials successfully produced include Hy/Zn-BDC, Hy/Zn-Fer, and Hy/Zr-BDC. Antibacterial activity testing shows that adding MOF into the hydrogel matrix significantly increases the inhibition against S. aureus and E. coli compared to the hydrogel without MOF. Among the three MOF variants, Hy/Zn-BDC showed the highest antibacterial activity, followed by Hy/Zn-Fer and Hy/Zr-BDC. Specifically, Hy/Zn-BDC inhibited S. aureus growth by 95% and E. coli by 100%, accompanied by the lowest effective inhibitory concentration values (2.0 mg/mL and 2.4 mg/mL, respectively). These results demonstrate the high effectiveness of Zn-based MOF in enhancing the antibacterial performance of the hydrogel as well as its potential development for wound dressing applications.
Transformasi Digital Pariwisata Halal Berkelanjutan di Perdesaan: Perspektif Trickle-Down terhadap Pengembangan Strategis Rahem, Abdul; Soleh, Mochammad; Prayoga, Adistiar; Ekowati, Juni; Naufal, Adam Mochammad; Hanif, Muhammad Ihsan; Jannah, Qonita Miftahul; Putri, Fauzha Amalya Purnama; Nafi'a, Ilma Arrafi; Nurrohmah, Zidni ‘Ilmatun; Jupriadi, Lalu; Bayani, Faizul; Yaqin, Ainul; Mochammad Naufal, Adam
TRI DHARMA MANDIRI: Dissemination and Downstreaming of Research to the Community (Journal of Community Engagement) Vol 6 No 1 (2026)
Publisher : SMONAGENES Research Center, Univeritas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtridharma.2026.006.01.48

Abstract

Program pengabdian kepada masyarakat ini bertujuan mengembangkan potensi agroeduwisata halal berbasis madu trigona melalui pemberdayaan pelaku usaha mikro dan kecil setempat. Program ini mengatasi hambatan berupa keterbatasan kapasitas kelembagaan, pemanfaatan sumber daya alam yang belum optimal, serta rendahnya literasi digital pelaku usaha. Intervensi yang dilakukan meliputi pelatihan Sistem Jaminan Produk Halal, pemasaran digital, penyusunan rencana konten, serta pendampingan intensif sertifikasi halal dan Nomor Induk Berusaha. Hasil analisis menggunakan uji t berpasangan menunjukkan peningkatan pengetahuan peserta yang signifikan secara statistik dengan nilai p < 0,0001 dan ukuran efek kategori besar (dz = 0,83). Hal ini membuktikan efektivitas program dalam meningkatkan kompetensi sumber daya manusia secara nyata. Selain meningkatkan daya saing pelaku usaha mikro dan kecil, kegiatan ini mengimplementasikan Trickle-Down Theory melalui pengembangan sektor strategis untuk menciptakan ekonomi inklusif. Program ini juga berkontribusi pada pencapaian Sustainable Development Goals, khususnya pada aspek kesehatan, pertumbuhan ekonomi, komunitas berkelanjutan, dan kemitraan multipihak. Secara keseluruhan, integrasi pemberdayaan masyarakat dan penguatan ekosistem halal ini menjadi model pembangunan perdesaan yang berkelanjutan.
Pelatihan Pembuatan Minuman Kesehatan Berbasis Kunyit pada Masyarakat Desa Tenaru, Gresik, Jawa Timur: Training on Making Turmeric-Based Health Drinks for the Tenaru Village Community, Gresik, East Java Juni Ekowati; Arie Sulistyorini; Suzana Suzana; Andang Miatmoko; Kholis Amalia Nofianti; Farida Ifadotunnikmah; Diajeng Putri Paramita; Firmansyah Ardian Ramadhani; Dwi Setyawan; Noorma Rosita; Muh. Agus Syamsur Rijal; Ersanda Nurma Praditapuspa; Winanda Rizki Febrianti; Dita Savitri; Adam Pratama
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 6 (2026): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v11i6.11420

Abstract

Turmeric is a herbal remedy with a million benefits that has been used by Indonesians for centuries. Tenaru Village, one of the villages, produces a lot of turmeric annually in Gresik Regency. However, this turmeric is sold only as a cash crop or a simple product at a low price. This program aims to provide training for Tenaru village farmers to create innovative turmeric-based products to increase their selling value. Furthermore, this program aims to increase participants' understanding of safe food packaging as part of safe, high-quality food products. The program's success was evaluated quantitatively, showing a statistically significant increase in pre- and post-test scores. The qualitative assessment using Bloom's taxonomy analysis showed an increase in participants' abilities, from not knowing to being able to teach other people in that village. This indicates that the program has had a significant impact on participants' ability to develop innovative turmeric-based instant beverage products.
Co-Authors Abdul Jabbar, Davano Al Raffi Abdul Rahem, Abdul Achmad Toto Poernomo Achmad Toto Purnomo Adam Hermawan Adam Pratama Adinda Adelia Wulandari Afandi, Ryan Ainul Yaqin Ainurrizma, Dhea Ananda Akhmad Aminur Rizqia Alief Putriana Rahman Anang Setyo Wiyono Andang Miatmoko Ardhayanti, Erlina Arie Sulistyorini Asri Darmawati Bambang Tri Purwanto Bastiana Bastiana Bayani, Faizul Bermawi, Bastiana Dewi Isadiartuti Dewi Melani Hariyadi Dini Retnowati Dita Savitri Diyah, Nuzul Wahyuning Diyah, Nuzul Wahyuning Djoko Agus Purwanto Dwi Setyawan Edy Meiyanto Edy Meiyanto Eko Pujiono, Feri Elkania Putri, Safira Engrid Juni Astuti Erawati, Erawati Erika Christy Marentek Esti Hendradi Etik Wahyuningsih Farida Ifadotunnikmah Febrianti, Winanda Rizki Fery Eko Pujiono, Fery Eko Fery Pujiono, Fery Firmansyah Ardian Ramadhani Galih Satrio Putra Galih Satrio Putra Ghifari, Aileen Syifa Ghinalya Chalbi Ananda Ghinalya Chalbi Ananda Gusti Rizaldi Hadi Poerwono Handayani, Rosita Hanif, Muhammad Ihsan Hanifah Ridha Rabbani Hariyadi, Dewi Melany Hartono, Thalia Vanessa Heinrich Dengi Hidayati, Shabrina Wahyu I NYOMAN WIJAYA Ichsanto, Farhan Hanang Ida Kristianingsih Ilham Bagus Sagitaras Imamatin Nufus Melania Isnaeni isnaeni, isnaeni isnaeni Isnalita Istna Nur’ainul Yaqin Itsna Nur ‘Ainul Yaqin Iwan Sahrial Hamid Jannah, Qonita Miftahul Jupriadi, Lalu Kanzaffa, Firly Afnauriza Tedja Kholidah Febriani Kholis Amalia Nofianti Lia Agustina, Lia Luqmanul Hakim M. Faris Adrianto Mangestuti Agil Marcellino Rudyanto Maulia, Arwinda Melanny Ika Sulistyowati Melanny Ika Sulistyowaty Moch Davit Abdul Majid Mochammad Naufal, Adam Mochammad Yuwono Mohammad Rizki Fadhil Pratama Muh. Agus Syamsur Rijal Muhamad Ilham Royyan Nafi’ Muhammad Agus Syamsur Rijal Muhammad Faris Adrianto, Muhammad Faris Muhammad Ilham Royyan Nafi Muhammad Yuwono Muhammad Yuwono Muhammad yuwono Muhammad yuwono, Muhammad Yuwono Muhammad Yuwono Nafi'a, Ilma Arrafi Naufal, Adam Mochammad Ninis Yuliati, Ninis Noor Erma Nasution Noor Erma Nasution Noor Erma Nasution Noor Erma Nasution Sugijanto Noor Erma Nasution Sugijanto Noorma Rosita Norhayati Norhayati Nurrohmah, Zidni ‘Ilmatun Nusandari, Ratna Paramita, Diajeng Putri Pebrianti, Denayu Poernomo, A.Toto Praditapuspa, Ersanda Nurma Pratama, Adam Prawitasari, Neny Prayoga, Adistiar Pujiono, Ferry Eko Purnomo, Ahmad Toto Purwitasari, Neny Putri Hamidah Khairunnisa Putri, Fauzha Amalya Purnama Rahman, Ave Rahmana Emran Kartasasmita Rais Razak Randiman, Sugijanto Sugijanto Rani, Karina Citra Retno Sari Rian Putra Pratama Rianti, Dian Ratna Riesta Prima Harinastitic Rijal, Agus Syamsur Rossa Auli Tasha Ruri Intan Nurcahyaningtyas Sariwati, Atmira Savitri, Orchidea Meidy Nurintan Setiawan, Albertus Aditya SETIAWAN, Catur Dian Setyo Wiyono, Anang Shigeru Sasaki Shigeru Sasaki Shihab, Fawaz Siswandono Siswandono, Siswandono Siswandono, Siswandono Siti Rahmah Soleh, Mochammad Soraya, Yasmin Sovia Aprina Basukia Suciati Suciati Sugijanto Sugijanto Kartosentono Sugijanto Kartosentono Sugijanto Sugijanto Sugijanto Sugijanto Randiman Sugijanto, Noor Erma Nasution Noor Erma Nasution Sukardiman Suko Hardjono Sulistyowati, Melanny Ika Susanto, Julian Dwi Suwarno Putra, Adryansyah Suzana SUZANA, SUZANA Syahrani, Achmad Tahta Amrillah Tiara Puspa Asriningrum Tri Ana Mulyati, Tri Ana Tri Widiandani Tutuk Budiati Tutuk Budiati Ulvan, Angkasa Megistra Wardani, Siska Widji Soeratri Winanda Rizki Febrianti Winantari, Agnes Nuniek Wiwied Ekasari Yaqin, Istna Nur’ainul Yusniasari, Putri Antika Yusuf, Helmy