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All Journal Medula Juke Jurnal Dunia Kesmas Jurnal Kreativitas PKM JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Medika Hutama Essential: Essence of Scientific Medical Journal Prosiding Konferensi Nasional PKM-CSR Journal of Comprehensive Science Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Journal of Student Research Sains Medisina Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Majority Jurnal Riset Multidisiplin Edukasi JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Galen: Jurnal Ilmu Farmasi dan Kesehatan SNTE JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Rani Himayani
Unknown Affiliation
Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Polytrauma dan Injury Severity Score (ISS) Gigaramadan Sema; Helmi Ismunandar; Rani Himayani; Risti Graharti
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.834

Abstract

Polytrauma is trauma that occurs at several areas on the body, followed by decline in physiological function which has the potential to cause multiple organ dysfunction and death in patients. Initial assessment of polytrauma is important to identify injuries that require initial treatment, determine the management of these injuries, and assess the patient's prognosis. There are several scoring systems that can be used to assess polytrauma injuries. Abbreviated Injury Scale (AIS) can be used to assess the severity of the injury and the probability of death of the patient. The Injury Severity Score (ISS) is a scoring system that assesses the three most severe injuries from six body regions. New Injury Severity Score (NISS) is an update from ISS; assessment of the three most severe injuries to the body regardless of body region. These assessment methods can help the trauma care system to better prevent complications and death in polytrauma patients.
Carotid Cavernous Fistula Neli Salsabila; Rani Himayani
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Carotid cavernous fistula (CCF) is an abnormal communication between arteries and veins within the cavernous sinus. The most common (70%-90%) etiology of CCF is trauma and spontaneus CCF (30%) due to aneurysms or the presence of atherosclerotic arteries. Various symptoms can be found in cases of CCF such as conjunctival chemosis, proptosis, pulsating exophthalmus, diplopia, ophthalmoplegia, orbital pain, bruits and blindness. Sometimes spontaneous CCF is misdiagnosed as conjunctivitis or late in diagnosis. Cranial nerve damage and vision loss in CCF can become permanent if left untreated. Therefore, this paper aims to find out cases of CCF, from the history and physical examination so that if the diagnosis of CCF has been established in ophthalmologist, it will be referred to the neurosurgery for further management. The history for the etiology of CCF and ophthalmological examination to see the symptoms and signs in CCF cases, and the diagnosis can also be confirmed by radiological examination computed tomography scan (CT Scan) and cerebral angiography as the gold standard. Management of CCF in ophthalmologist with medical therapy or surgery if an increased intraocular pressure is obtained and the management of symptoms in the eye. Based on the patients’s symptoms, treatment can be observation, neuro-radiological intervention, or neurosurgical intervention.
Tinjauan Pustaka: Diagnosis Dan Tatalaksana Mastoidits Nadhia Wihelga; RA Genta Syakira Hatta; Putu Ristyaning Ayu Sangging; Rani Himayani
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 2 No. 1 (2023): April :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v2i1.1000

Abstract

Mastoiditis is a disorder of the middle ear. Inflammation of the middle ear involves the mastoid cells of the temporal bone. Mastoiditis is generally a complication of otitis media. This is due to the connection between the middle ear and the mastoid air cells. This research method begins by searching articles on Google Scholar, PubMed and NCBI within the year range determined by the researcher and using the keywords Mastoiditis, Mastoiditis Diagnosis, Mastoiditis Management. The results of this study found that the diagnosis of mastoiditis can be made by history, physical examination and supporting examinations. Treatment that can be done in mastoiditis depends on the severity of the infection and its complications. administration of antibiotics, incision and drainage of mastoid abscess and mastoidectomy are the management of mastoiditis
Literature Review: Kajian Potensi Interaksi Obat Antidiabetes Pada Pasien Diabetes Melitus Tipe 2 Dengan Komplikasi Hipertensi Natanael, Jessica; Damayanti, Ervina; Himayani, Rani; Oktafany, Oktafany
Sains Medisina Vol 2 No 6 (2024): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v2i6.468

Abstract

Diabetes melitus (DM) tipe 2 merupakan gangguan metabolik yang ditandai dengan kondisi hiperglikemia yang disebabkan oleh insufisiensi insulin parsial atau total. Hasil penelitian yang dilakukan oleh Valliyot et al. pada tahun 2013 menunjukkan bahwa orang yang memiliki riwayat hipertensi berisiko 5 kali lebih besar menderita diabetes melitus dibandingkan dengan orang yang tidak memiliki riwayat hipertensi. Pengobatan diabetes melitus bersamaan dengan komplikasi hipertensi dapat berhasil jika ditangani dengan terapi yang tepat, namun jika tidak berhasil akan mengakibatkan adanya interaksi obat pada penggunaan kombinasi obat untuk kedua penyakit tersebut. Interaksi obat terjadi ketika obat berinteraksi dengan makanan, minuman, zat kimia, atau obat lain yang mengubah efek obat yang diberikan bersamaan atau hampir bersamaan. Studi ini diharapkan dapat bermanfaat untuk mengetahui potensi interaksi obat pada pasien diabetes melitus dengan komplikasi hipertensi. Metode yang digunakan adalah literature review dengan menggunakan database Google Scholar dengan rentang tahun artikel tahun 2015 sampai tahun 2024. Dari hasil yang didapatkan dapat disimpulkan bahwa kombinasi obat yang paling banyak mengalami interaksi adalah metformin dan amlodipin dengan mekanisme interaksi obat yang paling banyak adalah farmakodinamik serta tingkat keparahan interaksi obat yang terjadi paling banyak pada kategori moderate.
Mata Kering pada Pasien Pascaoperasi Refraksi Mata Menggunakan Relex-Smile Hana Qanitah; Himayani, Rani
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.755

Abstract

The eye is an organ that has many functions and is a vital organ in the body. The eyes have a part called photoreceptor which functions as light detector that will be stream to the retina of eyes according to its function. Based on data obtained from WHO, around 217 million people in the world have visual impairments. Refractive errors have several ways to correct them, one of which is using LASIK or with Refractive Lenticule Extraction, Small Incision Lenticule Extraction (RELEX SMILE). In a study conducted at the Eye Center Hospital, Hangzhou, Zhejiang Province, China in 2015, the incidence of dry eye complaints after RELEX SMILE surgery was 11% - 24%. A hospital in Semarang, reported that the incidence of dry eye complaints after RELEX SMILE surgery was 12%. This research is a Literature review which is a type of research that gathers theories that are relevant to the material that is currently researched, namely regarding dry eye syndrome. Researchers collected a number of articles from several databases like MEDLINE/PubMed, Google Scholar, and national also international journals. The result of the study found several complications in the procedure for healing eye refractive errors using RELEX SMILE, one of which is dry eyes. Dry eyes after RELEX SMILE and LASIK surgery is caused by damage to the sensory nerves in the cornea which may be caused by incisions during surgery. The incidence of dry eye after RELEX SMILE surgery can be prevented by a thorough examination by looking for signs and symptoms of dry eyes, or using drops without preservatives to reduce the impact of dry eyes.
Hubungan Tingkat Pengetahuan Penggunaan Lensa Kontak Pada Pelajar
Sekolah Menengah Atas terhadap Risiko Ulkus Kornea di Bandar Lampung Ardella, Karina Belinda; Himayani, Rani; Utami, Nurul
Medula Vol 13 No 7 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i7.899

Abstract

Contact lenses are visual aids that can be used to correct refractive errors and for cosmetic purposes. Knowledge of contact lenses usage influence contact lens wearing behavior. Corneal ulcer can be caused by improper use of contact lenses. The objective of this study is to determine the correlation between knowledge level of contact lenses usage with the risk of corneal ulcer among high school students in Bandar Lampung. This quantitative analytic study with a cross-sectional design was conducted in December 2020 - February 2021. Research respondents consisted of 54 high school students in Bandar Lampung who match the criteria and were selected randomly. The research instrument was a questionnaire to assess knowledge of contact lenses usage and symptoms that accompany contact lens usage. Data were analyzed by Fisher test. In this study, as many as 47 respondents (87.0%) were female. There are 32 respondents (59.3%) who use contact lenses to correct eye refractive disorders. As many as 50 respondents (92.6%) have good knowledge and 4 respondents (7.4%) have sufficient knowledge. Respondents with red eyes and decreased visual acuity are 8 respondents (16,7%). Respondents who are at risk of corneal ulcer are 3 respondents (5.6%). In the analysis of the correlation between knowledge level of contact lenses usage and the risk of corneal ulcers, p value = 1,000. In this study, knowledge level of contact lenses usage has no correlation with the risk of corneal ulcers among high school students in Bandar Lampung.
Diabetes Mellitus Tipe 1 Fauziani, Andra Nabila; Adelia, Anggi; Ardika, Okta Besti; Himayani, Rani; Rahmanisa, Soraya
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.946

Abstract

Diabetes mellitus (DM) is a chronic condition with an increasing incidence worldwide. Not only does it occur in adults, but the incidence rate in children is also quite high. Type-1 DM is an autoimmune disease characterized by absolute insulin deficiency due to pancreatic gland cell damage. Although it can occur at any age, type-1 DM most commonly appears in adolescence with a peak onset around puberty. Diabetes mellitus is often caused by genetic factors and a person's lifestyle. Symptoms of Type 1 DM in children are the same as in adults: polyphagia, polydipsia, polyuria and nocturia, weight loss, and about a third suffer from diabetic ketoacidosis. Complications of diabetes can be divided into microvascular and macrovascular. Microvascular complications include nervous system damage (neuropathy), renal system damage (nephropathy) and eye damage (retinopathy), but can also affect cognitive function, heart and other organs. HbA1c screening is recommended every 3 to 6 months. HbA1c levels reflect glycemic control over the previous 2-3 months. The target HbA1c is generally <7.0%. Other laboratory tests include lipid profile, serum creatinine, eGFR, and urine albumin to creatinine ratio. Management of Type 1 DM includes insulin injection, blood sugar monitoring, nutrition, physical activity, and education. The goal of insulin therapy is to ensure that insulin levels in the body are sufficient for 24 hours to meet metabolic needs due to the glycemic effect of food.
Tinjuan Pustaka: Hubungan Jenis Kelamin dan Hormon Androgen dengan Kejadian Dry-Eye Disease Fairuz Hanan, Sifa’Syaharani; Rengganis Wardani, Dyah Wulan Sumekar; Rudiyanto, Waluyo; Himayani, Rani
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.992

Abstract

Dry eye disease (DED) is a multifactorial condition on the surface of the eye that occurs due to disruption of tear film homeostasis with manifestations of symptoms such as tear film instability, hyperosmolarity, inflammation, eye surface damage, and neurosensory abnormalities. DED can occur due to decreased eye fluid production or increased tear evaporation which is generally caused by meibomian gland dysfunction. The global prevalence of DED ranges from 5-50%, with women having a higher risk than men. The prevalence of dry eye in women (3.2 million) is higher than in men (1.6 million) aged over 50 years. Asian ethnicity is the most consistent risk factor for DED. The female gender factor is a risk in the development of DED with increasing age. The pathophysiological mechanisms of DED can be influenced by differences in endocrine function related to sex, especially androgen, estrogen and other hormones. The meibomian and lacrimal glands are target organs for androgen hormones, and low androgen activity can cause meibomian gland dysfunction and inflammation of the lacrimal glands, contributing to the occurrence of DED. In addition, differences in gene expression affect mucin production by the cornea and conjunctiva, as well as other hormonal involvement can also affect eye health and cause dry eye symptoms. Further understanding of the relationship between gender, hormones, and pathophysiological mechanisms of DED may aid the development of more effective treatment strategies.
Faktor-Faktor yang Mempengaruhi Health Related Quality Of Life (HRQoL) pada Pasien Penyakit Jantung Koroner Tanpa Penyakit Terminal Lubna Farhana; Ramdini, Dwi Aulia; Himayani, Rani; Junando, Mirza
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1045

Abstract

Coronary heart disease (CHD) is a disorder in heart function caused by narrowing of the coronary arteries and atherosclerotic plaque, leading to inadequate oxygen supply to the myocardial muscle. According to the World Health Organization (WHO) data from 2012, CHD is the number 1 cause of death with a percentage of 38.3% of total deaths. Patients with CHD commonly experience symptoms such as chest pain and shortness of breath, which significantly impact in their health-related quality of life (HRQoL). Additionally, complex treatment can also have a broad impact on HRQoL. The aim of this article is to identify the factors influencing HRQoL in CHD patients. In this study, a literature review method was employed, utilizing online databases such as Elsevier, PubMed, Springer. Factors such as social support, comorbidities, lifestyle, disease condition, self-management, and sociodemographic factors are known to influence HRQoL in CHD patients.
Hiperglikemia Pada Terapi Nutrisi Parenteral Dwi Anjani, Galuh; Junando, Mirza; Oktarlina, Rasmi Zakiah; Himayani, Rani
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1050

Abstract

Hyperglycemia is a condition that often occurs in some patients on parenteral nutrition therapy, both with and without a diagnosis of diabetes mellitus. The incidence of hyperglycemia is closely related to an increase in length of stay and mortality in hospital. This literature review aims to provide an overview of the management of hyperglycemia related to parenteral nutrition therapy. The source search method was carried out using the Google Scholar, Pubmed and Elsevier search engines. The keywords used are management of hyperglycemia, risk factors, parenteral nutrition. Based on the results of the literature review, it was found that several factors trigger the incidence of hyperglycemia, including BMI > 25 kg/m2, advanced age, higher HbA1c, history of type 2 DM, use of glucocorticoid drugs and administration of excess carbohydrates and reduced insulin sensitivity. Several strategies to prevent hyperglycemia are carried out by providing low dextrose, hypocaloric parenteral nutrition, or combining parenteral and enteral nutrition. Providing combined nutrition can improve glycemic control in patients with sufficient endogenous insulin stores. Meanwhile, therapeutic measures need to be given if hyperglycemia persists after preventative strategies are implemented. Therapeutic measures that can be taken include administering insulin intravenously or subcutaneously to patients in stable condition. Alternatively, insulin can be added to the parenteral nutrition mixture. It is important to closely monitor blood glucose levels to reduce the risk of hyperglycemia or hypoglycemia.
Co-Authors Ad-Dhuha, Rahmah Maziyah Adelia, Anggi Adrifianie, Femmy Ahmad Duta Al-Ihya Alfina Indah Nabila Amalia Febriyanti Ambarwati, Endah Amelia, Erry Rizki Amira Nabila Andrifianie, Femmy Angelica Philia Christy Anggraeni Janar Wulan Anindia Syafia Halimathus Sa'dyah Aprianti, Shervia Dwi Ardella, Karina Belinda Ardika, Okta Besti ari wahyuni Ari Wahyuni Ari Wahyuni Arif Yudho Prabowo Asep Sukohar Betta Kurniawan, Betta Brigitta Shinta dewi Cahyana, Adinda Husna Carissa Aprilia Y Chindy Annisa Putri Mandala Sempaga Cut Karel Dithia Daffa Fahreiza Damayanti, Ervina Devina Hardianto Devira Fitriani Kamal Dewayanti, Wahyu Dwi Anjani, Galuh Dwi Indria Anggraini Edward Sintong Samosir Ellysa Angguman Putri Ety Apriliana Ety Apriliana Evan Christian Christian Fadhilah, Fuad Fadilah Alwiyah Fairuz Hanan, Sifa’Syaharani Faisal Rohmadhiyaul Haq Faisol Rohmadhiyaul Haq Faridi Pani Farraz Kanya Syahra Fauzan Hafizh, Ahmad Fauziani, Andra Nabila Fayza Syachrani Febri Nadyanti Febrianti, Arlin Fernadya Sylvia Nurindi Firsandini, Firsandini Fitria Saftarina Ghaitsa Lulua Ghifari, Ghaza Ahmad Al Ghiffari, Fahman Ghina Salsabila Fenty PNR Gigaramadan Sema Gigih Forda Nama Giska Tri Putri Graceciela, Yohana Eva Hana Qanitah Hanifah Qollama Astrid Hanna Mutiara, Hanna Happy, Terza Aflika Helmi Ismunandar Helmi Ismunandar Hendra Tarigan Sibero Hery Dian Septama Ida Laila Ihsanti Dwi Rahayu Ika Agustin Putri Haryant Imtinan Khoirunnisa Intan Kusumaningtyas Intanri Kurniati Junando, Mirza Junita, Aulia Kadek Elvina Kusuma Putri Kamila Nastiti Keziah Tirtawijaya Khairun Nisa Kurnia Fithrananda Kurniawan, Diva Ardhana Lintang Lestari Cahya Sawitri Lubna Farhana M Yusran M. Revo Artmando L M. Yusran Maharani , Mentari Putri Mallarangeng, Andi Nafisah Tendri Adjeng Mardiana Mardiana Maretta, Alvina Christy Maureen Angelica Melni Armadani Mentari Putri Maharani Mochamad Fauzan Dava Muhammad Aditya, Muhammad Muhammad Arsy Kamal Faadhil Muhammad Maulana Muhammad Maulana Muhammad Yusran Muhartono Muhartono Mukhlis Imanto Nabila Alsa Sagia Nabila Rayhan Yasmin Nadhia Wihelga Nahrassyiah Rahma Putri Naila Fathiya Isnanto Nashwa Faadillah Nasyim Natanael, Jessica Neli Salsabila Ni Made Karenina Rini Dwi Cintawan Noval Ramadirta Nurhaliza, Rahma Nurul Fadhilah Az-zahro Nurul Purna Mahardika Nurul Utami Okki Muhammad Fajar Muthahhari oktadiani, Isna Oktafany, Oktafany Oktaryona Trisera Oktoba, Zulpakor Prayogi, Norbertus Marcell Putu Ristyaning Ayu RA Genta Syakira Hatta Rachel Agustin Inggrid Zefanya Rahmah, Nisrina Nur Ramadhan Triyandi Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rasmi Zakiah Oktarlina Regita Dwi M Rekha Nova Iyos, Rekha Nova Rengganis Wardani, Dyah Wulan Sumekar Renitta Anggraeni Rifka Putri Dewi Riska Azzahra Risti Graharti Ristyaning Ayu Sangging, Putu Rizki Hanriko Rizqiani Astrid Nasution Rudiyanto, Waluyo Ruth Leria Noverika Salsabila Haqya Kusuma Sangging, Putu Ristyaning Ayu Saphira Murfi Septiani, Linda Serafina Subagio Shifa Azzahra, Nimas Sitanggang, Grety Soraya Rahmanisa Suharmanto Susanti, Andani Dewanti Sutarto Sutarto Sutarto Sutarto Syachrani , Fayza Syahrani Alya Murfi Syazili Mustofa Syiva Ulhayah T. Adjeng, Andi Nafisah Thamara Az Zahra Tri Umiana Sholeha Tri Umiana Soleha Tri Umiana Soleha Tsurayya Fathma Zahra Vania Widyadhari Damayanti Widjaja, Jovan Wildan Kautsar Irawan Wiwi Febriani Yashila Rahimah Yasmin, Deffina Widya Yuliant, Titin Yusran, M Zenith Puspitawati Zheva Aprillia Yozevi