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All Journal Jurnal Penelitian Saintek INOTEKS : Jurnal Inovasi Ilmu Pengetahuan, Teknologi, dan Seni EKSAKTA: Journal of Sciences and Data Analysis SPEKTRUM INDUSTRI International Conference on Engineering and Technology Development (ICETD) Medical Journal of Indonesia Rekayasa Mesin Journal Industrial Servicess The Indonesian Biomedical Journal Molecular and Cellular Biomedical Sciences (MCBS) JURNAL DINAMIKA VOKASIONAL TEKNIK MESIN Seminar Nasional Teknologi Informasi Komunikasi dan Industri Prosiding SENTIKUIN (Seminar Nasional Teknologi Industri, Lingkungan dan Infrastruktur) Eksakta : Berkala Ilmiah Bidang MIPA Jurnal Respirologi Indonesia Jurnal Ilmu dan Teknologi Kesehatan Pharmaceutical Journal of Indonesia Majalah Patologi Indonesia Social, Humanities, and Educational Studies (SHEs): Conference Series Jurnal Ilmiah Teknik Industri Kumawula: Jurnal Pengabdian Kepada Masyarakat Health Information : Jurnal Penelitian jurnal Teknik Industri - Unisi Jurnal Rekayasa Industri (JRI) Indonesian Journal of Global Health research BioEksakta : Jurnal Ilmiah Biologi Unsoed REKA ELKOMIKA: Jurnal Pengabdian kepada Masyarakat Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang JOURNAL LA MEDIHEALTICO Journal of Engineering and Applied Technology Narra J Jurnal Perak Malahayati : Pengabdian Kepada Masyarakat Jurnal Rekayasa, Teknologi, dan Sains Jurnal Ilmiah Kesehatan (JIKA) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Indonesian Journal of Applied and Industrial Sciences (ESA) Jurnal Pustaka Dianmas Jurnal Bakti Masyarakat Manajemen Jurnal Penelitian dan Pengabdian Kepada Masyarakat (JPPM) Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Jurnal Polimesin Jurnal Akuntansi Pajak dan Manajemen Folia Medica Indonesiana Journal of Applied Mechanical Engineering Innovation
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The Increase in CD14+CD16+ Monocytes is Correlated with Cardiovascular Disease Risk Marker in Type 2 Diabetes Hikmat, Ujang Saeful; Prijanti, Ani Retno; Wibowo, Heri; Sukmawati, Indriyanti Rafi; Tahapary, Dicky Levenus
The Indonesian Biomedical Journal Vol 16, No 1 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i1.2798

Abstract

BACKGROUND: Type 2 Diabetes (T2D) impairs the innate immune system including monocytes. Monocytes are divided into two subgroups depending on the expression of cluster of differentiation (CD)14 and CD16 receptors, namely CD14+CD16- and CD14+CD16+. CD14+CD16+ are proinflammatory monocytes and develop into M1 type macrophages, which contribute to foam cell production, a risk factor for cardiovascular disease (CVD). Therefore, it is important to determine the influence of T2D conditions on changes in monocyte subsets and whether these changes correlate with CVD risk markers.METHODS: Peripheral blood mononuclear cell (PBMC) was obtained from 10 T2D subjects and 10 healthy donors. Subsequently, PBMC was incubated for 24 hours with and without 10 mL lipopolysaccharide. Flow cytometry was used to evaluate CD14 and CD16 expression, while multiplex immunoassays were applied to measure interleukin (IL)-1b and IL-10 concentrations in supernatants.RESULTS: In T2D, the percentage of CD14+CD16+ monocytes increased (p=0.07), and an increase in CD14+CD16+ monocytes more than 6.8% was linked with CVD risk markers (r=10.146, p=0.002). Meanwhile, inflammatory mediators released by monocytes shown an increase in IL-1b (p=0.041) but not in IL-10 (p=0.082) in T2D subjects. Fasting blood glucose levels were also found to be substantially linked with an increase in CD14+CD16+ monocytes (r=0.530, p=0.016).CONCLUSION: T2D patients had a higher percentage of CD14+CD16+ monocytes and IL-1b levels than healthy donors. An increase in CD14+CD16+ monocytes above 6.8% associated with CVD risk markers in T2D patients.KEYWORDS: type 2 diabetes, monocytes, CD14, CD16, cardiovaskular disease risk marker
Optimasi Prosedur Kultur H9C2 Kardiomioblas: Sebuah Pembelajaran untuk Membangun Model Studi In-vitro Kardiovaskular Fadhillah, Muhamad Rizqy; Arozal, Wawaimuli; Wibowo, Heri
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 5, ISSUE 1, April 2024
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/EKSAKTA.vol5.iss1.art8

Abstract

Cardiovascular disease become one of the leading factors of death in the world. Thus, research is urgently needed to discover newer drugs or therapeutical agents and biological plausibility. The H9C2 cardiomyoblast originated from embryonic BDIX rat ventricular cells and was previously used in numerous in vitro studies because of its similar nature to cardiomyocytes. However, to our knowledge, there are still limited studies on the basic procedure for culturing H9C2 cardiomyoblast and arranging the best strategy to perform a suitable timeline. Here, we shared our experience in culturing the H9C2 cardiomyoblast, including harvesting and subculturing the cells. We also demonstrated the change of cell confluency, depending on the seeding number, serum concentration, and culture flask through days 1, 3, and 6, to determine their doubling-time population. H9C2 cardiomyoblasts’ doubling time is around 48-54 days with Mean±SD 2.38±0.41. However, seeding density, different culture flasks, and serum concentration have become independent factors in determining specific measures to harvest the cells for further experiments.
Application of the Consumer Protection Law in Electronic Transactions Wibowo, Heri; Sebyar, Muhamad Hasan
Indonesian Journal of Applied and Industrial Sciences (ESA) Vol. 3 No. 3 (2024): May 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/esa.v3i3.9271

Abstract

This research aims to determine the implementation of consumer protection laws in e-commerce transactions in Indonesia. The method used in this research is a normative legal research method with a statutory approach. The data collection technique is literature study. The data in this research uses primary and secondary data. The research results show that the implementation of the law in this Law is carried out through several steps, including (1) enforcing special regulations created to regulate consumer rights and obligations in relation to electronic transactions, (2) the government taking firm action against violations of consumer rights in electronic transactions involving law enforcement officials. (3) increase consumer awareness. Various initiatives educate and inform consumers about their rights and potential risks and how they can protect themselves when making online transactions.
EXPERIMENTAL INVESTIGATION ON THE MECHANICAL BEHAVIOR OF VACUUM INFUSION CFRE COMPOSITE WITH VARYING ORIENTED CARBON FIBER AND ITS APPLICATION ON ACTUAL COMPONENTS Mujiyono, Mujiyono; Utomo, Yoga Wahyu; Nurhadiyanto, Didik; Wibowo, Heri; Arifin, Achmad
Jurnal Rekayasa Mesin Vol. 16 No. 1 (2025)
Publisher : Jurusan Teknik Mesin, Fakultas Teknik, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/jrm.v16i1.2010

Abstract

Carbon fiber-reinforced epoxy (CFRE) has better performance properties and is commonly used in the aviation industry. The placement of carbon fiber will affect the mechanical properties of the resulting composite material. The specific application to actual components has yet to be discovered regarding the mechanical capabilities of the CFRE utilization. Therefore, it is essential to investigate further the mechanical behavior of CFRE composites with varying oriented carbon fibers, especially those produced using the vacuum infusion method with a volume fraction of 40%. This study presents an experimental investigation of the CFRE composite with varying oriented carbon fibers in unidirectional, bidirectional, and forged. The result shows composite materials' mechanical characteristics, particularly in the properties of Young's modulus, Poisson ratio, and shear modulus. The unidirectional fiber composites are only suitable for tensile loads in line with the fiber, while bidirectional fiber composites should be cautiously undertaken, as tensile loads applied to the Z-axis may lead to adverse effects; conversely, shear forces can be safely applied to all three axes. The forged fiber direction results in each loading direction having separate capabilities, which are challenging to anticipate. The application of CFRE on an actual component should entail the integration of diverse fiber orientations within a single composite layer, particularly in highlighting manufacturing folding arm components and their adaptability. The test results demonstrate that the maximum load that can be tolerated by the folding arm before failure fulfills the requisite strength criteria, thus allowing for a safety factor of 7.8, which confirms the safety of the CFRE with combined fiber orientation in producing folding arm components.
THE DEVELOPMENT OF THE COURSE MODULE OF MANUFACTURING ENGINEERING DRAWING FOR VOCATIONAL STUDENTS Riyadi, Andrian; Wibowo, Heri
Jurnal Dinamika Vokasional Teknik Mesin Vol. 8 No. 2 (2023)
Publisher : Department of Mechanical Engineering Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/dinamika.v8i2.66820

Abstract

This research developed a learning modules that fit the curriculum and determine the level of eligibility to be applied in learning of Manufacturing Drawing Engineering. This research applied  a Research & Development methode with the 4D model from Thiagaradjan, that are Define, Design, Develop, and Disseminate. The developed course module was validated by material and media experts which is presented using Likert scale. The results of the validation from the lecturers as material experts scored 3,33 in very feasible category, the validation from the lecturers as media experts scored 3,35 in very feasible category, the validation from the teachers as material experts scored 3,04 in feasible category, and the validation from teachers as media experts scored 3,35 in very feasible category. Products that have been developed and revised were tested on 30 students of XI class in Mechanical Engineering department of SMK Negeri 3 Yogyakarta by distributing evaluation questionnaires to find out the responses of students. The product got a score 3,58 from the students in very feasible category. The module received a very feasible evaluation from lecturers as a material and media experts, teachers as a media experts, and students. The module received a feasible evaluation from teachers as a material experts.
Maternal IgG in hemolytic disease of the fetus and newborn-ABO incompatibility Wibowo, Heri; Nurrahmah, Sheila; Gantini, Ria Syafitri Evi
Medical Journal of Indonesia Vol. 33 No. 2 (2024): June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247269

Abstract

BACKGROUND Hemolytic disease of the fetus and newborn (HDFN) is a type of anemia in the fetus or newborn, characterized by anemia, jaundice, hyperbilirubinemia, and brain damage. IgG is the only antibody that can cross the placenta. The IgG subtypes have a different ability to destroy red blood cells (RBCs). IgG1 and IgG3 can bind to Fc-phagocyte cell receptors and cause hemolysis, while IgG3 has more ability than IgG1. This study aimed to identify the antibody IgG subtype contributing to clinical manifestation differences in HDFN. METHODS This study used blood and umbilical cord blood samples from 30 pairs of mother-baby. The samples were grouped into control (not jaundice/normal bilirubin levels) and jaundice/hyperbilirubinemia groups. A self-developed IgG subtype enzyme-linked immunosorbent assay protocol was performed on maternal samples, resulting in optical density. Statistical analysis was performed using SPSS software version 23. RESULTS Blood type was associated with total bilirubin expression (p = 0.005). IgG1 anti-A, IgG3 anti-A, IgG4 anti-A, IgG1 anti-B, IgG3 anti-B, and IgG4 anti-B significantly affected hyperbilirubinemia in newborns (p = 0.041, 0.013, 0.017, 0.028, 0.001, and 0.007, respectively). CONCLUSIONS IgG1 and IgG3 were more significant in causing clinical problems. IgG4 suppressed IgG activation, resulting in no destruction of the infant’s RBCs.
TREND POSITIF: LEWAT GERAKAN HIJAU DAN KREATIVITAS MEMASAK PADA KELOMPOK REMAJA DI DESA DAYEUHKOLOT KABUPATEN BANDUNG Yunita, Desi; Lesmana, Aditya Candra; Wibowo, Heri; Amanatin, Elsa Lutmilarita
Kumawula: Jurnal Pengabdian Kepada Masyarakat Vol 8, No 3 (2025): Kumawula: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/kumawula.v8i3.62822

Abstract

Remaja berada dalam fase perkembangan yang penuh tantangan, terutama saat menghadapi dilema pilihan hidup dan risiko seperti putus sekolah dan keterbatasan biaya pendidikan. Kegiatan pengabdian ini bertujuan memberikan edukasi untuk memperkuat dan memotivasi cara berpikir remaja melalui pola tren positif, yang diwujudkan dalam praktik hulu-hilir berbasis potensi dan permasalahan sosial, dengan fokus pada gerakan hijau dan kreativitas memasak. Pendekatan yang digunakan melihat persoalan remaja sebagai bagian dari masyarakat berisiko. Namun, risiko tersebut dapat diprediksi dan diupayakan penyelesaiannya. Metode pengabdian dilakukan melalui pemetaan sosial sederhana, dilanjutkan dengan analisis sebab-akibat dari permasalahan remaja. Selanjutnya, ditentukan tahapan pengabdian dengan mengangkat tema tren positif serta memberikan informasi dan strategi program penyetaraan pendidikan serta peluang beasiswa. Hasil dari kegiatan ini terlihat dari partisipasi aktif dan respons positif para remaja selama proses edukasi berlangsung. Remaja di Desa Dayeuhkolot memperoleh gagasan baru dalam melihat persoalan dan peluang, serta memiliki cara pandang yang lebih konstruktif dalam mengatasi permasalahan yang mereka hadapi.
Pemberdayaan UMKM Kue Kering Sagon Ibu Sita Wibowo, Heri; Anggraini, Meilani; Khikmawati, Emy; Wardana, Marcelly Widya; Fattah, Kemas Muhammad Abdul
Jurnal Perak Malahayati: Pengabdian Kepada Masyarakat Vol 7, No 2 (2025): Volume 7 Nomor 2 November 2025
Publisher : Program Studi Kebidanan Fakultas Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jpmpkm.v7i2.23692

Abstract

Usaha Mikro Kecil dan Menengah (UMKM) merupakan kategori usaha yang memiliki skala kecil dan menegah, yang biasanya dikelola oleh individua tau kelompok Masyarakat. UMKM memiliki peran penting dalam perekonomian, karena mereka menciptakan lapangan kerja, mendorong inovasi, dan berkontribusi pada pertumbuhan ekonomi local. UMKM Kue Kering Sagon Bu Sita Adalah salah satu UMKM yang berada di Pekon Tanjung Kurung Kecamatan Wonosobo Kabupaten Tanggamus, yang mana usahanya bergerak dibidang pengolahan pembuatan kue kering. Kegiatan Pengadian kepada Masyarakat (PkM) ini bertujuan untuk memberdayakan kehidupan ekonomi Masyarakat setempat dalam berwirausaha, serta memberikan motovasi pentingnya berwirausaha. Target yang ingin dicapai dalam kegiatan ini Adalah mendapatkan peluang untuk berwirausaha dengan sumber daya yang dimiliki oleh Masyarakat setempat, sehingga dapat meningkatkan pendapatan keluarga serta dapat membuka lapangan kerja. Hasil kegiatan ini juga diharapkan meningkatkan penjualan produk dengan memberikan pengetahuan tentang desain produk, manajemen usaha, dan strategi pemasaran, sehingga hasil produksinya dikenal oleh Masyarakat luar dan menjadi sumber daya yang potensial.
Relation between length of stay and anti-filarial igg4 level in pondok gede sub-district, bekasi district, west java Susatyo, Jeffry Adijaya; Wibowo, Heri
Folia Medica Indonesiana Vol. 53, No. 3
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Filariasis is a contagious disease caused by worms of the genus Filaria which transmitted through the bite of various species of mosquitoes. In Indonesia, the existence of filariasis cases are still very concerning. Jati Sampurna and Jati Karya villages in Pondokgede Sub-district, Bekasi District, West Java have been known as filariasis endemic area. Length of stay is presumed as one of many factors that affects filariasis occurrence in those villages. This study aimed to determine the distribution of anti-filarial IgG4 on the region and its comparison with the length of stay and residence status. This study was based on secondary data. Secondary data were obtained from primary research data done by cross-sectional method. These data were used to assess the correlation of filarial infection risk factors in pregnant women living in endemic areas based on the distribution of anti-filarial IgG4 in Pondok Gede, Bekasi district, West Java. The study showed that there was an increase in anti-filarial IgG4 against residence status (p=0.017) and a positive correlation between the number of anti-filarial IgG4 with length of stay in years (p=0.003).
A Analysis of Tempering Treatment after Hardening on S45C steel Bogie Pin Materials in relation to Mechanical Strength Wibowo, Heri; Marwanto, Arif; Kusdiyarto, Prihatno; Prasetio, Mukhamad Andri
Journal of Engineering and Applied Technology Vol. 6 No. 02 (2025): (August)
Publisher : Faculty of Engineering, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jeatech.v6i02.90400

Abstract

S45C steel is a medium carbon steel used for railway bogie pins due to its high strength. However, this steel does not meet the minimum hardness standard for bogie pin products, requiring further processing. The specific objectives of this study are: a) to investigate the effect of tempering temperature variations on the mechanical properties of S45C steel, and b) to determine the optimal tempering temperature and time recommended for heat treatment of S45C steel. The research method applied was an experiment with hardening treatment at a temperature of 910°C for 20 minutes, followed by tempering treatment at temperatures of 175°C, 225°C, and 275°C for 20 minutes of air cooling. The testing process carried out included tensile strength testing, hardness testing, and microstructure testing. The results of this study showed that the test specimen with tempering treatment at a temperature of 175℃ was the best among the other test specimens because it was more suitable for industrial needs. This test specimen had a maximum stress value of 948.6 MPa, a maximum strain value of 7.76%, a Vickers hardness value of 358.06 VHN, and a microstructure consisting of ferrite and martensite phases, making the tempering process at a temperature of 175℃ almost close to the standards set by the company.
Co-Authors -, Hidayat . Sulastri Achmad Arifin Aditya Candra Lesmana Agung W. Ahmad Sidiq Akmala, Vaza Aldho Jaya P. Aldino, Rio Yuri Aldyth Gunanto P. Alghifari, Fajar Alida Roswita Harahap Amanatin, Elsa Lutmilarita Andari, Ni Nyoman Destri Andrian Riyadi Anggono, Rendi F. Anggraini, Meilani Anggraini, Melani Anggraini, Melani Ani Retno Prijanti Ani Retno Prijanti Anna Rozaliyani Antonius H. Pudjiadi Ardani Ahsanul Fakhri Ardani, Yanuar Ardhias Mahendra P. Ardi Maulana Nugraha Aria Kekalih Ariyanto Ariyanto Arleni Bustami Aryono Hendarto Asysyifa, Nisrina Badranaya, Muhammad Imawan Bambang Heru Budianto Bima Lantip B. Clarinta Putri, Rizky Damayanti, Triya Dante Saksono Harbuwono Desi Yunita Dewi Sukmawati Dian R. Sawitri, Dian R. Dicky Levenus Tahapary Didik Nurhadiyanto Dilawar, Ismail Dimyati, Arzaq Guruh Dinda Zulwi Amalia Tifani E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edy Purnomo Em Yunir, Em Emy Khikmawati Ernawati Evy Yunihastuti Fadhillah, Muhamad Rizqy Fattah, Kemas Muhammad Abdul Ferry Sandra Findra Setianingrum Fredy Surahmanto Gantini, Ria Syafitri Evi Garda Kharisma Sidanta Gede Wirya Kusuma Duarsa Gusti Khatimah, Nurul Hadiyanto Abdul Rachim Hamdani Nurbahri Hanif Nur Hidayat Hayati, Taureni Hidayat - Hidayat, Entus Hikmat, Ujang Saeful Hutabarat, Hernayati I Wayan Agus Hariyanto Ida Parwati Ilman, M.Noer Indah Setiawati Indrasari, Nuri Dyah Irfan Wahyudi Iris Rengganis Irwansyah Irwansyah Joedo Prihartono Julian Katarina, Matilda Kemas Muhammat Abdul Fatah Khatimah, Nurul Gusti Kuncoro Adi, Rahmad Kusmardi Kusmarinah Bramono Kwarta, Cytyta Putri Liem, Isabella Kurna Liem, Isabella Kurnia Lisnawati Rachmadi M. Rafi Marcellus Simadibrata Marcellus Simadibrata Marcelly Widya Wardana Masyur, Muhtaruddin Mawardi, Prasetya Melani Anggraini Mohamad Sadikin Muhamad Hasan Sebyar Muhammad Fedryansyah, Muhammad Muhammad Luthfi Muhammad Noer Ilman Mujiyono Mujiyono Mujiyono Mujiyono Mulyadi M. Djer Mulyani, Ayu Murdani Abdullah Murni, Indah K. Najib Advani Neng T. Kartinah Novi H Nur Azizah Nur Irawati Nuraeni, Hanny Siti Nurbahri, Hamdani Nurrahmah, Sheila Nurwati, R. Nunung Parhusip, Santi Sumihar Rumondang Piprim B. Yanuarso, Piprim B. Ponco Birowo Pradipta, Saraswati Prasetio, Mukhamad Andri Prihatno Kusdiyarto Primadhani, Suci Widya Primariadewi Rustamadji Priyo Tri Iswanto Putera, Raka Hilmi Syah Putri Damayanti Putri, Rizky Clarinta Raharja, Putu Angga Risky Rani Wardani Hakim Ratnawati, Mamik Reza Y. Purwoko Ricardo, William Rike Kurniawan Rio Yuri Aldino Ririn Probowati, Ririn Riski Amanda, Clara Risty Yasmin Bonita Riswan Dwi Djatmiko Rona Kartika Rozaliyan, Anna Rubiana Sukardi, Rubiana Sarwono, Sugeng J. Savitri, Monika setianingrum, suci Sidiq , Ahmad Soleha, Winna Sresta Azahra Sri Widia A. Jusman Sri Yamtinah Suhendro Suhendro Sukamto Koesnoe Sukoarno, Sukarno Sulastri Sulastri Supanto, Muhammad Supriatna, Novianti Supriono , Untung Susanti, Dasmi Susanti, Dhama S. Susatyo, Jeffry Adijaya Suyatna, Fransiscus Dhyanagiri Syari, Lucky Novita Tiara Mayang Pratiwi Lio Tjhin Wiguna Triana, Novi Utomo, Yoga Wahyu Wahyu Gunawan Wahyu, Fransiska Wahyurini, Dyahati Wawaimuli Arozal Widodo Apriliyanto Wijaya, Rheza Paleva Windy Keumala Budianti Wresti Indriatmi B. Makes Yonita, Ariska Yusra Yusra