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Effects of Aerobic Exercise and Yoga Breathing Exercise (Pranayama) on Blood Pressure in Hypertensive Patients Khairunissa, Khairunissa; Tamtomo, Didik Gunawan; Prasetya, Hanung
Journal of Epidemiology and Public Health Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Uncontrolled hypertension or high blood pressure is a major risk factor for cardiovascular disease. Non-pharmacological treatment has become an important part of hypertension management. Aerobic exercise and yoga breathing exercise (pranayama) are types of non-pharmacological treatment that have an effect on lowering blood pressure. This study aims to examine the effect of aerobic exercise and yoga breathing exercise (prana
Risk of Death in COVID-19 Patients with Comorbidity of Chronic Kidney Disease: Meta Analysis Rohmah, Isna Nur; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Coronavirus disease 2019 or known as COVID-19 was a disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). There are seven comorbidities that experience the most severity and death when infected with COVID-19, namely hypertension, diabetes mellitus, cardiovascular disease, chronic obstructive pulmonary disease, chronic kidney disease, cerebrovascular disease, and cancer. This study aimed to estimate the magnitude of the risk of death in COVID-19 patients with comorbid chronic kidney disease, with a meta-analysis of primary studies conducted by previous authors.Subjects and Method: This study was a systematic review and meta-analysis with the following PICO, population: COVID-19 patients. Intervention: comorbid chronic kidney disease. Compa
The Effectiveness of Ivermectin on the Risk of Mortality in COVID-19 Patients: A Meta Analysis Pamilih, Ayu Trisni; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: The Coronavirus Disease 2019 (COVID-19) has become the highest priority of global pandemic. New and repurposed drugs are being tested on mild to moderate levels of COVID-19 to help suppress transmission of the virus. Ivermectin is one of the repurposed drugs with known safety records with more than 2.5 billion doses dispensed in the past. This study aims to estimate the effectiveness of ivermectin in reducing the risk of mortality in COVID-19 patients based on the results of a number of previous similar studies.Subjects and Method: This study is a systematic review and meta-analysis. This study used secondary data in the form of data from previous study results. A systematic and comprehensive database search was carried out through several databases including: PubMed, Science Direct, Google Scholar, and Springer Link. Analysis of this study was using RevMan 5.3 software. This study used the eligibility criteria with the PICO model, populations: covid-19 patients, intervention: ivermectin administration, comparison: patients without ivermectin, outcome: mortality in COVID-19 patients. The inclusion criteria used were full paper in English and Indonesian with a randomized controlled trial, including the number of deaths, and the primary study was conducted in a hospital. The keywords used to search the database were
Meta-Analysis Correlations between Hypertension, Smoking, and Severity Risk of COVID-19 Larsiani, Lisa Safaah Novia; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.03.04

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Background: Based on the reported cases, 16.9% of COVID-19 patients were accompanied by comorbidities. Hypertension and smoking are suspected to be one of the pathological determinants that play a role in clinical predictors that are predicted to cause a worsening of the patient's condition during the treatment period. This study aimed to examine correlations between hypertension, smoking, and severity risk of COVID-19.Subjects and Method: Meta-analysis was carried out using PRISMA flow diagrams. Article searches through journal databases include: PubMed, Science Direct, Google Scholar. articles used in 2020-2022. The PICOs in this study were, Population: COVID-19 patients, Intervention: hypertension and smoking Comparation: not hypertension and not smoking, Outcome: severity of COVID-19. The keywords in this study were “hypertention” OR “high blood pressure” AND “severe COVID-19” OR “severty COVID-19” OR “patient COVID-19 outcome” “cigarette” OR “smoking” OR “current smoker” OR former smoker” AND “severe COVID-19” OR “severty COVID-19” OR “patient COVID-19 outcome” Inclusion criteria were articles used in full paper articles with a cohort design, relationship size used with aOR, intervention given the association of hypertension and smoking on the severity of COVID-19. Eligible articles were analyzed using the Revman 5.3 application.Results: A meta-analysis of 12 cohort articles originating from Asia, America, Africa, Europe, concluded that COVID-19 treatment patients with hypertension had higher severity 1.82 times compared to those without hypertension (aOR= 1.82; 95% CI= 1.18 to 2.79; p=0.006). Likewise, COVID-19 treatment patients with smoking habit had higher severity than those who do not smoke (aOR= 0.62; 95% CI= 0.14 to 2.65; p=0.520).Conclusion: COVID-19 patients with hypertension have an increased risk of severity. COVID-19 patients with smoking lower risk of severity. Keywords: Severe COVID-19, hypertention, cigarette. Correspondence:Lisa Safaah Novia Larsiani. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: nl.lisasafaah@gmail.com Mobile: 089536503803.
Meta-Analysis the Impact of Social Restriction during COVID-19 Pandemic on Blood Glucose Control in Type 1 Diabetes Mellitus Patients Pratiwi, Yeocelin Mega; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.03.11

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Background: The COVID-19 lockdown has an impact on the daily lives of people with type 1 diabetes, including restrictions on physical activity, changes in diet, difficulty contacting health care providers and concerns about drug supplies. The purpose of this study was to analyze the impact of the COVID-19 lockdown on blood sugar control in type 1 diabetes mellitus patients.Subjects and Method: This research is a meta-analysis study using PRISMA flowchart guidelines. The PICO model used is Population= type 1 diabetes mellitus patients. Intervention = COVID-19 lockdown. Comparison = before the COVID-19 lockdown. Outcome = HbA1c. The article search process was carried out between 2019 and 2022 using online databases from PubMed, Springer Link and Google Scholar. The keywords used in the article search were “Quarantine” OR “Quarantines” OR “Stay at Home Orders” OR “Health Lockdowns” OR “Self-Quarantine” OR “Self-Quarantine” AND “Diabetes Mellitus” OR “Diabetes Insipidus” OR “Diabetic” OR “Glucose Intolerance” AND “Glycemic Control” OR “Blood Glucose Control”. The inclusion criteria used in this study were full paper articles with cohort studies, using English or Indonesian, the intervention given was COVID-19 lockdown, and the outcome was blood glucose level (HbA1C) in diabetes mellitus patients.The analysis was performed using RevMan 5.3 software.Results: A total of 11 articles reviewed in the meta-analysis showed that the impact of the COVID-19 lockdown decreased HbA1c levels by 0.23 compared to before the COVID-19 lockdown in patients with type 1 diabetes mellitus and was statistically significant (SMD= -0.23; 95% CI -0.29 to -0.18; p<0.001).Conclusion: COVID-19 lockdown reduces HbA1c levels compared to before COVID-19 lockdown in type 1 diabetes mellitus patients. Keywords: COVID-19 lockdown, type 1 diabetes mellitus, HbA1c. Correspondence:Yeocelin Mega Pratiwi. Masters Program in Public Health, Universitas Sebelas Maret. Jalan Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: yeocelinmega@gmail.com. Mobile: 082137652605.
Effect of Diabetes Mellitus Comorbidity on Mortality Risk in Tuberculosis Patients who Received Tuberculosis Treatment: A Meta-Analysis Anasulfalah, Hakim; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.04.03

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Background: Tuberculosis or TB is a disease caused by the Mycobacterium tuberculosis complex. There are several comorbidities that experience severity and death when infected with tuberculosis or TB, namely hypertension, diabetes mellitus, cardiovascular disease, chronic kidney disease, cerebrovascular disease, and other diseases. This study aims to estimate the magnitude of the risk of death in Tuberculosis patients undergoing treatment with comorbid Diabetes Mellitus, with a meta-analysis of primary studies conducted by previous authors.Subjects and Method: This was a systematic review and meta-analysis with the following PICO, population: Tuberculosis patients. Intervention: comorbidities of chronic diabetes mellitus. Comparison: without comorbid diabetes mellitus. Outcome: death. The articles used in this study were obtained from three databases, namely Google Scholar, Pubmed, and Science Direct. Keywords to search for articles “Tuberclosis” OR TBC AND “Diabetes Mellitus” OR DM AND Mortality OR Death The included full-text articles are in English with a cohort study design from 2007 to 2021 and report the adjusted Odds Ratio (aOR) in a multivariate analysis. Article selection is done by using PRISMA flow diagram. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 12 cohort studies involving tuberculosis patients undergoing treatment from America, Europe, Africa and Asia were selected for a systematic review and meta-analysis. The data collected showed tuberculosis patients undergoing treatment with comorbid Diabetes Mellitus had a 1.68 times risk of death compared to COVID-19 patients without comorbid chronic kidney disease (aOR = 1.68; 95% CI = 1.42 to 1.99; p<0.001).Conclusion: Diabetes mellitus comorbidity increases the risk of death in tuberculosis patients undergoing treatment. Keywords: Diabetes Melitus, Tuberculosis, mortality Correspondence:Hakim Anasulfalah. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: isnanr28@gmail.com. Mobile: 081327215685.
Effectiveness of COVID-19 Vaccine on Augmenting Antibody Level in People in the Special Region of Yogyakarta, Indonesia Budiyono, Joko; Murti, Bhisma; Tamtomo, Didik Gunawan
Journal of Epidemiology and Public Health Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.01.04

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Background: Immunity against SARS-CoV-2 is needed to prevent infection so vaccines are indeed humanity's great hope as a weapon to control COVID-19. Seroprevalence data is needed using an antibody test that estimates the percentage of DIY residents who have antibodies against SARS-CoV-2. This study aimed to determine the effectiveness of COVID-19 vaccination on enhancing antibody titers.Subjects and Method: This was a retrospective cohort study conducted in Yogyakarta, Indonesia, from 19 to 30 November 2021. The study population was people aged ≥1 year. A total of 563 study subjects was selected randomly. The dependent variable was the SARS-CoV-2 antibody titer level. The independent variables were COVID-19 vaccination status, gender, age, smoking, outdoor activities, and alcohol consumption. SARS-CoV-2 antibody level was measured using Roche's Elecsys anti-SARS-CoV-2. Other variables were collected using questionnaires. Data were analyzed using a multiple linear regression run on STATA 14.Results: The initial vaccination led to an elevation in -19 antibody titers, but it was statistically non-significant (b= 697.82; 95% CI= -720.90 to 1241.24; p= 0.603). The second vaccination resulted in a notable and statistically significant elevation of COVID-19 antibody titers (b= 1331.38; 95% CI= 802.30 to 1860.46; p <0.001).Conclusion: The second dose of the COVID-19 vaccination demonstrated significant effectiveness in boosting COVID-19 antibody titers. Keywords: COVID-19, vaccination, antibody
Effect of Tertiary Preventive Behavior on HbA1c Level, Quality of Life, and Complication Risk in Diabetes Mellitus Patients Livia, Wardhatul; Murti, Bhisma; Tamtomo, Didik Gunawan; Prasetya, Hanung
Journal of Epidemiology and Public Health Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.01.10

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Background: Type 2 diabetes mellitus (DM) is a non-communicable disease which is a source of additional severity for other diseases. This study aims to determine the effect of tertiary preventive behavior on hba1c level, quality of life (QoL), and complication risk in diabetes mellitus patients.Subjects and Method: This was a cross-sectional study conducted in Sukoharjo, Central Java, Indonesia, from October to November 2023. A total sample of 200 patients with type 2 diabetes mellitus (DM), registered in the Prolanis program, was selected through multistage random sampling. The independent variables were HbA1c levels, risk of complications, and QoL. The inde-pendent variable was tertiary preventive behavior. HbA1c levels were measured using spectrophotometer. QoL was measured using the WHOQOL questionnaire, and risk of complications using a questionnaire. Data were analyzed using the SEM model.Results: Tertiary prevention behavior significantly increased HbA1c level (b= 0.31; CI 95%= -0.45 to 0.15; p<0.001) and quality of life (b= 0.15; 95% CI= -0.15 to 0.38; p<0.001). Tertiary prevention behavior significantly reduced the risk of complications (b= -0.22; CI 95%= -0.42 to 0.02; p= 0.026). The goodness-of-fit values suggest that the structural equation model (SEM) is acceptable (p= 0.188; RMSEA=0.04; CFI=0.97, TLI=0.95; SRMR=0.05; CD= 0.07).Conclusion: Tertiary prevention behavior significantly increased HbA1c level and quality of life. Tertiary prevention behavior reduces the risk of complications in type 2 DM patients. Keywords: Diabetes mellitus, HbA1c, complications, quality of life
The Effect of Sleep Disorders on Anxiety and Depression in Health Workers: A Meta-Analysis Rohmani, Alfiana Nur; Murti, Bhisma; Tamtomo, Didik Gunawan
Journal of Epidemiology and Public Health Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.03.04

Abstract

Background: Sleep disorders are a clinical condition when a person frequently experiences problems or decreased sleep quality that can lead to anxiety and depression. The purpose of this meta-analysis is to estimate and analyze the magnitude of the influence of sleep disorders on anxiety and depression in health workers based on the results of previous similar primary studies.Subjects and Method: Meta-analysis was performed on a primary study with a cross-sectional design. The research with the PICO format is as follows. Q: Health workers. I: Sleep disturbances < 8 hours per day; C: No sleep disturbances (Enough sleep > 8 hours per day). O: Anxiety and depression. The meta-analysis study was conducted by searching for articles from databases in electronic form using Google schoolar and Pubmed. This study was conducted by researchers in November 2023 by searching and selecting research data online conducted by previous primary data researchers in Pubmed and google scholar with a research period of 2016-2023. The keywords used in the primary data search were "Mental health" OR "Anxiety" OR "Depression" AND "Sleep disturbance" AND "Health worker" OR "Healthcare". The inclusion criteria for this study are complete articles using Cross-sectional research, published years from 2013-2023. The analysis of the articles in this study uses RevMan 5.3 software.Results: The meta-analysis in this study included 7 cross-sectional studies from Hong Kong, China, Bangladesh, Saudi Arabia, the United States, and Turkey. The total sample size is 5,267 samples. The risk of anxiety caused by sleep disturbances in health workers was 1.6 times compared to health workers who did not experience sleep disturbances (aOR=1.67; CI 95%=1.05 to 2.45; p= 0.030). the risk of depression caused by sleep disturbances in health workers was 1.32 times compared to health workers who did not experience sleep disturbances (aOR=1.32; CI 95%=0.81 to 2.15; p= 0.270).Conclusion: Sleep disorders increase the risk of anxiety and depression in health workers.
Meta-Analysis of the Effect of Telemonitoring on Blood Sugar Levels and Quality of Life in Diabetes Patients Sholihah, Anisa Asri; Tamtomo, Didik Gunawan; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Type 2 diabetes mellitus (DM), a chronic disease, requires continuous monitoring and treatment to have a better quality of life. Telemonitoring is a medium that may help in monitoring patients with type 2 DM. This study aimed to analyze the effect of using telemonitoring on blood sugar levels and quality of life of patients with type 2 DM with a meta-analysis study.Subjects and Method: This was a systematic review and meta-analysis conducted with PRISMA flow diagram. The arti­cles were collected through journal databases, including PubMed, Google Scholar, Science Direct, and ProQuest, published in 2000-2021. The keywords used were ("tele­medicine" OR "tele-monitoring" OR "tele-monitoring") AND ("diabetes" OR "diabetes mellitus" OR "diabetes mellitus type 2") AND ("glucose level") AND ("quality of life"). The searching of articles used the PICO model. Population: people with type 2 diabetes mellitus, Intervention: telemonitoring, Comparison: not using telemonitoring, Outcome: blood sugar level and quality of life. Inclusion criteria were full-text articles with Randomized Controlled Trial (RCT) study design, published in English, with the effect measure of Mean SD. Eligible articles were analyzed using Revman 5.3.Results: A meta-analysis of 11 primary studies on the use of telemonitoring of blood sugar level showed a decrease in blood sugar (HbA1c) levels in patients with type 2 diabetes by 0.20 times compared to not using telemonitoring (SMD= -0.20; 95% CI= -0.39 to -0.01; p= 0.040). A meta-analysis of 6 primary studies on the use of telemonitoring on quality of life showed an increase in quality of life in type 2 diabetes patients by 0.16 times compared to not using telemonitoring (SMD= -0.16; 95% CI= -0.29 to -0.03; p= 0.020).Conclusion: Telemonitoring can improve blood sugar levels and the quality of life of patients with type 2 diabetes.Keywords: telemonitoring, type 2 diabetes mellitus, quality of life, meta-analysisCorrespondence: Anisa Asri Sholihah. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Suta­mi 36A, Surakarta 57126, Central Java. Email: anisaasri92@gmail.com. Mobile: 085740972­908.Indonesian Journal of Medicine (2021), 06(03): 246-257https://doi.org/10.26911/theijmed.2021.06.03.02 
Co-Authors Adiansa, Rendi Adji Suwandono Afniratri, Atika Ahadiyati, Dyah Mubarokah Aisyah Nooratisya Aktif Cahyaning Tyas Alfian Muhajir Alifiyanti Muharramah Amalia, Rizky Nur Aprilianti Aminuyati Ammutammima, Ummu Fatihah Anasulfalah, Hakim Andriani, Anisa Andriyaningtiyas, Yudi Angga Ferdianto Annisa Avelia Arief Suryono Ariwardani, Betty Nurizky Avelia, Annisa Bhisma Murti Bhre Diansyah Dinda Khalifatulloh Budiarti, Esty Budiyanti Wiboworini Budiyono, Joko Burhannudin Ichsan Cahyo Setiawan Danang Ardiyanto Delfita, Tria Fora Dewi Shinta Dewi, Novita Herlita Diffah Hanim Diffah Hanim Dono Indarto Eka Miftakhul Jannah, Eka Miftakhul Endang Sutisna Sulaeman Enggar Anggraeni, Enggar Eni Nur Rahmawati Faried, Faried Effendi Surono Fatony, Riska Fajar Fitriah Fitriah Fitriah Fitriah Haliza, Afifah Nur Hanida, Amin Nur Hanif, Ihsan Hermanu Joebagio Indriyati Oktaviano Rahayuningrum Irwan, Viola Fathia Islami, Dian Dini Karlinda Karlinda Khairiyyah, Alimah Ulfah Khairunissa, Khairunissa Khairunnisa Kun'ain, Utin Ilma Agni Kurnianingsih, Widya Larsiani, Lisa Safaah Novia Livia, Wardhatul Lourena, Crysty Maki Zamzam Mala Nurilmala Marlina, Devi Marwanto, Dwi Mayangkara, Radit H. Muchsin Doewes Mufidah, Naili Zahrotun Mufidatun, Ikhtiarisca Olifia Nabilla, Jihan NADIA FARAH DIBA Nia Handayani Noor Alis Setiyadi Novian Anindito Santosa Novianto, Fajar Novika, Revi Gama Hatta Nurlia, Nazilla Ade Nurvitasari, Rahsunji Intan Pamilih, Ayu Trisni Permata, Annissa Devi Prameswari, Galuh Ayu Dyah Prasetya, Hanung Pratiwi, Danies Tunjung Pratiwi, Yeocelin Mega Prawito . Puspita, Wita Hana Puspitasari, Ratih Febrinasari Pusporini Rahardjo, Setyo Sri Rahayu, Putu Sri Rahmatika Nur Aini Ratih Puspita Febrinasari Ratna Dewi Kumalasari, Ratna Dewi Ratri, Maika RB. Soemanto Rita Adriani Benya Adriani Rofana Aghniya Rohmah, Isna Nur Rohmani, Alfiana Nur Rusdiyanti, Yunita Salamah, Siti Nafi'atus Sapja Anantanyu, Sapja Shinta Shinta Shinta Sholihah, Anisa Asri Siregar, Attila Yulaicha Advendila Siti Munawaroh Soemanto, RB Subiyanto, Achmad Arman Suciati, Ony Sukandriani Utami Sulahyuningsih, Evie Sumardiyono Sumardiyono Sutanto, Alfiani Vivi Syahbaniar, Desi Syamsiar, Syamsiar Tri Puji Pangesti Uki Retno Budihastuti Ulfah Hidayati Uliyanti Uliyanti, Uliyanti Umar, Alwan Dhafi Vitri Widyaningsih Wahyudi, Anwar Wicaksono, Emirza Nur Widayati, Anis Nur Widiantoro, Reza Widyarahma, Amanda Yatty Destani Sandy Yohan Yuanta, Yohan yulia lanti retno dewi Yulia Sari Yuniarti Karunia, Yuniarti Zainal, Dwi Trisnawati