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Characterization of Ethanol Extract from Agarwood (Aquilaria microcarpa Baill.) Leaf Rahmanto, Beny; Halwany, Wawan; Lestari, Fajar; Anwar, Khoerul; Triyasmono, Liling; Rizki, Muhammad Ikhwan; Turjaman, Maman
Jurnal Jamu Indonesia Vol. 3 No. 2 (2018): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v3i2.56

Abstract

The aim of this research is to determine the specific and non-specific parameter from ethanolic extract of A. microcarpa. Specific parameters such as the organoleptic properties, content of water and ethanol soluble compound, and chhromatogram profile of the extract. In contrast, the non-specific parameter includes drying losses, ash levels, microbiological contamination levels, and heavy metal contamination levels. The results showed that the organoleptic properties of ethanolic extract of A. microcarpa was thick, blackish brown color, bitter taste and have distinctive odor. The average content of water-soluble compounds of 66.93%, ethanol-soluble of 47.97%, and chromatogram profile with Rf 0.636. The non-specific parameters results were drying losses of 5.50%, total ash content of 3.73%, acid-insoluble ash of 2.13%, microbial contamination testing results of 1.2x102-5.5x103 colonies/g, and total mold/ yeast contaminants of 10-100 colonies/g. Heavy metal contamination Pb levels and Cd levels were 5.47 mg/kg and 0.19 mg/kg respectively. These studies suggested that the observed specific and non-specific parameters may be helpful for establishing pharmacopoeia standards of A. microcarpa and to ensure uniformity of extract effect.
STANDARISASI PARAMETER SPESIFIK DAN NON SPESIFIK PADA SIMPLISIA KULIT BUAH MUNDAR (Garcinia forbesii) ASAL KALIMANTAN SELATAN Sari, Anna Khumaira; Rizki, Muhammad Ikhwan; Triyasmono, Liling; Alfandani, Gina
BENZENA Pharmaceutical Scientific Journal Vol 2 No 01 (2023): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v2i01.3111

Abstract

Latar bekalang : Mundar (Garcinia forbesii) merupakan tanaman khas asal Kalimantan Selatan yang berpotensi sebagai bahan obat. Tamanan diolah menjadi simplisia harus memenuhi persyaratan untuk dapat digunakan sebagai bahan obat. Simplisia yang digunakan akan melalui uji parameter standar simplisia meliputi parameter spesifik dan non spesifik. Parameter spesifik yang akan diuji yaitu golongan senyawa, senyawa spesifik yang menggambarkan efek farmakologis sedangkan pada parameter non spesifik yang akan diuji adalah sifat kimia, fisika dan mikrobiologi yang akan mempengaruhi stabilitas dan keamanan obat.Tujuan : Menetapkan parameter spesifik dan non spesifik simplisia kulit buah mundar asal Kalimantan SelatanMetode : Pengujian yang dilakukan yaitu penetapan parameter spesifik dan parameter non spesifik yang ditetapkan meliputi organoleptik, mikroskopik, kadar sari larut pelarut tertentu, susut pengeringan, kadar abu tidak larut asam, kadar abu total, dan  cemaran logam berat. Sampel simplisia tanaman Mundar yang akan diuji berasal dari dua Kecamatan yang berbeda yaitu dari Kecamatan Karang Intan dan Kecamatan Beruntung Baru Kabupaten Banjar, Kalimantan Selatan.Hasil : Hasil analisis simplisia kulit buah mundar dari Kecamatan Karang Intan and Kecamatan Beruntung Baru masing-masing adalah organoleptik kedua sampel simplisia berupa serbuk coklat, asam, berbau khas. Hasil mikroskopik diperoleh terdapat epidermis, kolenkim dan parenkim mesocarp pada kedua simplisia. Kadar sari larut etanol kedua simplisia masing-masing 57,20±0,10% dan 58,57±0,49%, kadar sari larut air 66,93±0,23% dan 68,83±0,15%, susut pengeringan 5,40±0,26% dan 6,93±0,76%, kadar abu total 2,20±0,03% dan 2,49±0,02%, kadar abu tidak larut asam 0,04±0,02% dan 0,06±0,02%, cemaran logam berat Pb 0,007±0,000mg/kg dan 0,010±0,003mg/kg, Cd 0,006±0,001mg/kg dan 0,009±0,002 mg/kg.Kesimpulan : Hasil parameter spesidik dan non spesifik kedua sampel simplisia kulit buah G.forbesii memenuhi persyaratan standar.Kata kunci: Mundar, simplisia, spesifik, non spesifik.
Pemberdayaan Kader dan Lansia dalam Pengelolaan Serta Pemanfaatan Toga sebagai Upaya Dalam Mengatasi Hipertensi di Desa Sungai Batang Kabupaten Banjar Isnani, Nazhipah; Triyasmono, Liling; Rizki, Muhammad Ikhwan; Rahmatullah, Satrio Wibowo; Sandi, Dita Ayulia Dwi; Izma, Hayatun; Redanti, Hema Novita; Humaidy, Mizan; Amali, Dzikra Aulia
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 12 (2025): Volume 8 No 12 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i12.22551

Abstract

ABSTRAK Hipertensi merupakan salah satu penyakit tidak menular dengan prevalensi tinggi dan menjadi faktor risiko utama penyakit kardiovaskular. Salah satu upaya pencegahan yang dilakukan melalui pemberdayaan masyarakat dengan edukasi dan pemanfaatan Tanaman Obat Keluarga (TOGA). Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan kader serta lansia dalam pencegahan hipertensi di Desa Sungai Batang. Kegiatan ini dilakukan dengan metode ceramah interakif, diskusi, pemerian edukasi dan pelatihan pengolahan TOGA. Evaluasi pengetahuan peserta dilakukan menggunakan pre-test dan post-test, kemudian dianalisis secara deskriptif kuantitatif. Hasil dari kegiatan ini didapatkan peningkatan rata-rata pengetahuan peserta dari 87,14% pada pre-test menjadi 100% pada post-test, dengan nilai p=0,0001 yang menunjukkan perbedaan siginifikan. Selain itu, peserta juga memperoleh keterampilan dalam meracik ramuan herbal antihipertensi dari TOGA. Edukasi hipertensi dan pelatihan TOGA efektif meningkatkan pengetahuan dan keterampilan kader serta lansia dalam mendukung upaya promotif dan preventif pada penyakit hipertensi di Desa Sungai Batang. Kata Kunci: Hipertensi, Edukasi Kesehatan, Tanaman Obat Keluarga, Pemberdayaan Masyarakat.  ABSTRACT Hypertension is a non-communicable disease with a high prevalence and a significant risk factor for cardiovascular disease. One preventative measure is community empowerment through education and the use of Family Medicinal Plants (TOGA). This activity aims to improve the knowledge and skills of community health workers and the elderly in preventing hypertension in Sungai Batang Village. The activity used interactive lectures, discussions, educational presentations, and TOGA processing training. Participants' knowledge was evaluated using pre- and post-tests, then analysed descriptively using quantitative data. This activity showed an increase in average participant knowledge from 87.14% in the pre-test to 100% in the post-test, with a p-value of 0.0001 indicating a significant difference. Furthermore, participants also gained skills in preparing antihypertensive herbal concoctions from TOGA. Hypertension education and TOGA training effectively improved the knowledge and skills of community health workers and the elderly in supporting promotive and preventive efforts for hypertension in Sungai Batang Village. Keywords: Hypertension, Health Education, Family Medicinal Plants, Community Empowerment
Nutritional Content, Subchronic Toxicity, and Antidysmenorrhea Activity of Instant Herbal Medicine Mixture of Red Ginger and White Ginger Dewi, Vonny Khresna; Kirana, Rita; Rizki, Muhammad Ikhwan
Medical Laboratory Technology Journal Vol. 11 No. 2 (2025): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i2.685

Abstract

Dysmenorrhea is menstrual pain that occurs in 69.8% of women. Ginger (Zingiber officinale) contains various secondary metabolites with anti-inflammatory properties. This study aims to determine its characteristics, including nutritional value and stability, product safety through toxicity testing, and product efficacy. The research stages include research ethics testing and the production of instant powder from a mixture of red and white ginger. Nutritional content analysis included total fat, saturated fat, protein, and carbohydrates. Physical and chemical stability testing was carried out for three months. Subchronic toxicity testing used Wistar rats for 28 days by drawing blood before and after treatment, accompanied by liver delivery. Blood samples were analyzed for SGPT and SGOT levels. The test was conducted on 10 women aged 18-20, divided into two groups. The treatment group was given 20 grams of instant ginger in the morning and evening for 10 days, and compared with the control group without treatment. Pain was measured using a Visual Analog Scale (VAS) before and after the study. The study showed that instant ginger herbal medicine contained 0.83% total fat, 0.17% saturated fat, 3.73% total protein, and 35.42% total carbohydrates. The stability test results showed no changes in the physical and chemical parameters of the test. The results of the subchronic toxicity test showed that the body weight of mice, liver weight, SGOT levels, and SGPT levels of mice were normal. The activity test showed a decrease in pain from before to after administration of instant ginger, with an average VAS value of 7.8 to 4.2. This study concluded that instant ginger, a mixture of red and white ginger, has good nutritional content, is physically and chemically stable, is non-toxic, and is effective in reducing dysmenorrhea.
EVALUASI KEPUASAN ANGGOTA PD IAI KALIMANTAN SELATAN TERHADAP PENGGUNAAN APLIKASI SIAP MENGGUNAKAN METODE EUCS (END USER COMPUTING SATISFACTION) Muhammad Ikhwan Rizki; Surya Wahyudi; Herningtyas Nautika Lingga
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.512

Abstract

The Indonesian Pharmacists Association or Ikatan Apoteker Indonesia (IAI) is a professional organization of pharmacists in Indonesia. IAI has management at Central, Regional, and Branches. Organizational services for each IAI member use the Pharmacist Information System Application or Sistem Informasi Apoteker (SIAp). Evaluation of satisfaction in the Information System can use the EUCS (End User Computing Satisfaction) method. The purpose of this study was to determine the level of satisfaction of South Kalimantan pharmacists on the use of the SIAp application and management services. The research method uses an analytical survey with a cross sectional design. The instrument used is a questionnaire that has been tested for validity and reliability. This research has been submitted to the Research Ethics Commission. The population of this research is 1.151 pharmacists in South Kalimantan. Respondents who filled out the questionnaire were 540 pharmacists (95% confidence level). Questionnaires were distributed using a Google form that assessed the SIAP application from the aspects of Content, Accuracy, Format, Easy of User, and Timeliness. The results of the questionnaire were analyzed using a Likert scale, then the percentage of satisfaction levels interpreted with the categories very high (75.01 - 100%), high (58.34-75), less (41.65-58.33), low (24.98 -41.66), and very low (0-24.99). The results showed that members' satisfaction with the SIAp application from the aspect of Content 79.83% (very high), Accuracy 81.47% (very high), Format 82.32% (very high), Easy of Use 78.36% (very high), and Timeliness 75.52% (very high). Member satisfaction with Branches is 79.07% (very high), Regional is 77.93% (very high), and Central is 75.27% (very high). Conclusion: The level of satisfaction of PD IAI South Kalimantan Pharmacists with the SIAp Application is very high. Branch, Regional, and Central Services are very high.
Co-Authors Aghna Mafruha Zahrah, Aghna Mafruha Agung Nugroho Agustina, Ni Kadek Ayu Akbar, Nabila Hadiah Akhmad Nabil Akhmad Nabil, Akhmad Akhsanul Rahmatullah Alfandani, Gina Alifni Adha Bakti Amali, Dzikra Aulia Amalia Khairunnisa Amalia Khairunnisa Amalia Khairunnisa, Amalia Amalia Khirunnisa Ana Ulfah Anna Humaira Anna Khumaira Sari Anna Khumaira Sari Aprianto . Arnida Arnida Arnida Arnida Aulea Rahmawati Azhara, Desiya Damayanti Baharuddin Yusuf Baharudin Yusuf Barkinah, Tut Beny Rahmanto Beny Rahmanto Beny Rahmanto Buih, Putri Helena Junjung Devi Eka Pratama Dewi Kartika Dewi Sari Mulia Dewi, Anita Ratna Dewi, Vonny Khresna Difa Intannia Dyah Anggraeni Effendi, Ibrahim Rully Evi Mintowati Evi Mintowati, Evi Evi Mulyani Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fadlillaturahmah Fadlillaturahmah Fajar Lestari Fajar Lestari Fajar Lestari Fariz, Abshar Fauzi, Rakhmat Gina Alfandani Hayatun Izma Helmina Wati Heri Budi Santoso Herningtyas Nautika Lingga Hilneser Simamora Humaidy, Mizan Izma, Hayatun Khalifah, Sefa Nur Khoerul Anwar Khoerul Anwar Khoerul Anwar Khumaira Sari, Anna Kirana, Rita Laura Sarwo Liling Triyasmono Lutfi Chabib, Lutfi Madani, Al Malahayati, Siti Maman Turjaman Maman Turjaman Ma’shumah Ma’shumah Metty Amperawati Mia Fitriana Mohammad Rizki Fadhil Pratama Muhammad Rusydi Taufik Mutia Mawaddah Naning Kisworo Utami Naning Kisworo Utami Nashrul Wathan Nazhipah Isnani Normaidah, Normaidah Nugroho, Agung Nur Mahdi Nurlely, Nurlely Okta Muthia Sari Oktavia Indrati, Oktavia Putra, Aditya Maulana Perdana Rabiatul Adawiyah Rahma, Salsabila Fadiya Rahmanto, Beny Rahmatullah, Satrio Wibowo Rahmawati, Aulea Ramadhan, Fery Ramadhani , Syahrizal Ratnapuri, Prima Happy Redanti, Hema Novita Rorry Adivrio Rizky Salamiah . Salamiah Salamiah Samsul Hadi Sandi, Dita Ayulia Dwi Saragih, Triando Hamonangan Sari , Anna Khumaira Sari, Fitri Novita Sholihin, Muhammad Aditya Silviana, Mega Siswadi Siswadi Sofia Suratno Suratno Surya Wahyudi Susiani, Eka Fitri Susy Andriani Sutomo Sutomo Sutomo Sutomo Syifa Auliani Syifa Auliani Titin Nor Tjitradi, Sukhito Yohanes Totok Wianto Valentina Meta Srikartika Wawan Halwany Wawan Halwany Wawan Halwany Wawan Halwany, Wawan Yuni Kartika