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The Impact of a High-Fat Diet on Blood Glucose Levels Atta Celine Nouli Saruksuk; Jekson Martiar Siahaan; Irene Ruminta Tua Damanik; Endy Juli Anto; Jadeny Sinarta
Jurnal Kedokteran Methodist Vol. 17 No. 2 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i2.5374

Abstract

Background: Diabetes mellitus (DM) sufferers in the world and even inIndonesia are expected to continue to increase, especially type 2 DM(DMT2). DMT2 often occurs in people who are obese, the cause of obesityis often consuming foods that contain a lot of fat. Hyperlipidemia plays arole in the pathogenesis of pancreatic β-cell dysfunction.Research method: This study is an experimental laboratory study with apretest-posttest only controlled group design, using male white rats(Rattus norvegicus) with a sample size of 30 divided into 6 groups, namelythe normal group, the negative control group, the positive control group,the group given a high fatty diet (HFD). The independent variable is HFD,while the dependent variable is blood sugar levels. Data were analyzedusing the Anova test.Results: Giving HFD of 4 ml/day for 4 weeks has not been able to increaseKGD to hyperglycemic, this is thought to be because the HFD was notgiven for long enough so that insulin resistance had not occurred in thetest animals.Conclusion: Based on the results of the study, it was concluded that givingHFD for 4 weeks still could not increase KGD in male white mice tobecome hyperglycemic
Antihyperglycemic Effect of Polyherbal Tea From Moringa oleifera, Cymbopogon citratus, and Stevia rebaudiana Leaves in Alloxan and HFD-Induced Mice (Mus musculus) Barukh Saro Talenta Zebua; Jekson Martiar Siahaan; Alex M. T. LumbanRaja; Suryati Sinurat; Salomo Garda Utama Simanjuntak
Jurnal Kedokteran Methodist Vol. 17 No. 2 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i2.5375

Abstract

Diabetes Mellitus (DM) is a disease with metabolic disorders characterized by chronichyperglycemia and disorders of carbohydrate, fat, and protein metabolism due to insulinsecretion disorders. In general, DM patients require pharmacotherapy such as injectedinsulin or oral antidiabetic drugs. Pharmacological treatment is relatively expensive andneeds to consider its efficacy and safety. Therefore, this study explores natural sources suchas medicinal plants. The aim of this study was to determine the antihyperglycemic effect of acombination of boiled moringa leaves, lemongrass leaves and stevia leaves on mice (Musmusculus) induced by alloxan. In this study, 25 mice were divided into 5 groups. The micewill undergo adaptation for 7 days and then given HFD for 30 days. After 30 days, the micewill be given alloxan 170 mg/kgBW for 3 days to induce DM. After DM was successfullyinduced in mice, polyherbal tea combination of moringa leaves, lemongrass leaves and stevialeaves was made and given, then continued with evaluation blood glucose, blood glucosepercentage, body weight, body weight percentage, index lee and liver organ index. The groupgiven herbal tea combination of moringa leaves (Moringa oleifera), lemongrass leaves(Cymbopogon citratus) and stevia leaves (Stevia rebaudiana) with a concentration of 3.6mg/mL showed a better decrease in KGD and %KGD compared to other treatment groups.The decrease in BB, %BB and lee index was better in the group given a combination ofMoringa leaves (Moringa oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevialeaves (Stevia rebaudiana) with a concentration of 7.2 mg/mL. The decrease in the liverorgan index was also better seen in the group given a combination of Moringa leaves(Moringa oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevia leaves (Steviarebaudiana) with a concentration of 7.2 mg/mL. The group given herbal tea combination ofMoringa leaves (Moringa oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevialeaves (Stevia rebaudiana) with a concentration of 3.6 mg/mL reduced BG and BGpercentage, while the group given herbal tea combination of Moringa leaves (Moringaoleifera), Lemongrass leaves (Cymbopogon citratus) and Stevia leaves (Stevia rebaudiana)with a concentration of 7.2 mg/mL reduced BW, BW percentage, Lee index, and hait organindex.
Family support as a predictor of breastfeeding self-efficacy among postpartum mothers Purba, Tetty Junita; Peny Ariani; Mutiara Dwi Yanti; Putri Ayu Yessy Ariescha; Friska Ernita Sitorus; Jekson Martiar Siahaan
Nursing and Health Sciences Journal (NHSJ) Vol. 6 No. 1 (2026): March 2026
Publisher : KHD-Production

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53713/nhsj.v6i1.665

Abstract

While family support is widely acknowledged as a critical determinant of breastfeeding self-efficacy, research on its independent predictive effect remains sparse. This limitation is particularly pronounced among postpartum mothers in Indonesia, where context-specific evidence is currently insufficient. This study aimed to analyze the relationships and effects of family support, educational level, and parity status on postpartum mothers' breastfeeding self-efficacy. A multicenter cross-sectional study was conducted among 180 postpartum mothers recruited from nine primary health centers across urban, semi-urban, and rural areas using purposive sampling. Family support was measured using a Friedman-based questionnaire, and breastfeeding self-efficacy was assessed using the Breastfeeding Self-Efficacy Scale–Short Form (BSES-SF). Spearman correlation and multiple linear regression were performed. Family support showed a moderate positive correlation with breastfeeding self-efficacy (rs = 0.559, p < 0.01). In multivariate analysis, family support remained the strongest predictor of breastfeeding self-efficacy (β = 0.509, p < 0.01), followed by parity (β = 0.255, p < 0.001), whereas maternal education was not statistically significant. Family support is the primary determinant of breastfeeding self-efficacy among postpartum mothers. Interventions to improve breastfeeding outcomes should integrate family-centered support strategies, particularly for first-time mothers.
Co-Authors Ade Setiowati Agnes Imelda Manurung Ahmad Abiyyu Muda Lubis Ainun, Nur Azizah Alex M. T. LumbanRaja Alprindo Sembiring Meliala Ardinata, Dedi - Ariani, Peny Ariescha, Putri Ayu Yessy Atmawidjaja, Rachmat Atta Celine Nouli Saruksuk Bahar, Dinillah Salsabila Barukh Saro Talenta Zebua Br Purba, Debora May Sary Br. T. Tambun, Gita Sradha Budi Darmanta Sembiring Butar-Butar, Harry Chalil, M. Jalaluddin A. Cristian Marito Siregar Damanik, Irene Data, Hariati Daulay, Agus Husein Diani Nazma Dina Riani Purba Dona Pasaribu Dwi Lunarta Doderina Siahaan Efbertias Sitorus Efrata, Efrata Eka Samuel P. Hutasoit Elvana, Ayu Endy Juli Anto Endy Juli Anto Endy Juli Anto endyjulianto endyjulianto Fadinie, Wulan FAHDI, FIRDAUS Fauzi, Tengku M. Fauzi, Tengku Muhammad Firdaus Fahdi Frengky S. Manullang Friska Ernita Sitorus Girsang, Rostiodertina Girsang, Rostiodertina Hadyanto Lim Hadyanto Lim Hakim, Enggrek Pelita Hamdi, Tasrif Harahap, Nurul Dahlia Hariati Hariati Hariati, Hariati Hendrika A. Silitonga Hendrika Silitonga Hutagalung, Mangatas Halomoan Parluhutan Hutagalung, Sanggam B. Hutagalung, Sanggam Bangun Hutapea, Kenal P. Hutasoit, Eka Samuel P. Ilyas, Syaffrudin Imelda Montes Monika Simanungkalit Indra Satrio Anantha Hasugian Irene Ruminta Tua Damanik Irfan Hamdani, Irfan Irina, Sinta Jadeny Sinarta Jadeny Sinatra Jadeny Sinatra Jan Pieter Sihombing Jenita Oktavia Panjaitan Jones Simatupang Juli Anto, Endy Juli Jamnasi Juli Jamnasi Juli Jamnasi Juli Y. Mega kenvin rusli Laura Octavina Siagian Lesmana Syahrir Lesmana Syahrir, Lesmana Lubis, Andriamuri P. Maestro B. U. Simanjuntak Maludin Panjaitan Manik, Widya Dayanti Feronika Manullang, Frengky S. Maria, Lasma Mega, Juli Yosa Menang Bastanta Tarigan Momot, Estela Salomina Mutiara Dwi Yanti Nababan, Manaor Bismar Posman Nababan, Titus Imanuel Nadapdap, Thomson P. Nainggolan, Ranatha NH Nainggolan, Serevina Napitupulu, Helen Debora Natalie S., Karen Noviola Sari Kusuma Sagala Nurmala Sari Nurmala Sari Pakpahan, Edwin Anto Panataria, Lince Romauli Panjaitan, Bintang Andika Panjaitan, Goklas Parhusip, Rudolf S. Pasaribu, Sumihar Paul Saut Marganda L Tobing Pengarapen Tarigan Perangin-angin, Guntur Pratiwi, Ade Dwi Purba, Amril Purba, Tetty Junita Putri C. Eyanoer Putri Chairani Eyanoer Putri Chairani Eyanoer, Putri Chairani Rahmi, Sofia Ria Oktavia Ricke Loesnihari Rifqi Aufan Rika Puspita Sari Rimbun, Surjadi Ronald T. H. Tambunan Ronald T. H. Tambunan Sagala, Daniela Salamon, Yuda Monang Salomo G. U. Simanjuntak Salomo Garda Utama Simanjuntak Salomo Garda Utama Simanjuntak Sanggam B Hutagalung Sanggam B. Hutagalung SARAGIH, MEYLIN KRISTINA Sari, Nur Mala Sembiring, Bob Agustinus Sembiring, Budi Darmanta Sembiring, Mikael Siahaan, Dwi Lunarta D. S. Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sihombing, Amordekhai Imvan Parlindungan Sihombing, Parsaoran Sihotang, Ruth Wydia Wati Sijabat, Kesia Silaen, Ester L. R. Silalahi, Veraci Silangit, Thomas Silitonga, Hendrika Adriana Silitonga, Hendrika Andriana Silitonga, Hendrika Andriani Simangunsong, Batara Simanjuntak , Salomo G. U. Simanjuntak, Jeremia Simanjuntak, Maestro Simanjuntak, Maestro Bina Utama Simanjuntak, Pantas Simanjuntak, Salomo Garda Utama Simanjuntak, Salomo Garda Utama Simatupang, Aditia Erick Cantona Simbolon, Boyke M. Sinatra, Jadeny Sinurat, Suryati Sirait, Kilian Sitepu, John Frans Siti Normi, Siti Sitompul, Michael Sabatino Sitorus, Friska Ernita Sitorus, Ragnar Oktavianus Situngkir, Jesica Damayanti Stephanie S., Kezia Sucipto Sucipto Surjani, Lylys Suryati Sinurat Suryati Sinurat Syahputra, Fahmi Tambunan, Nur Lela E. Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tampubolon, Ruth Septianna Br. Tanjung, Qodri F. Tarigan, Gracecilia Tarigan, Juliyanti Tarigan, Leonardo Tarigan, Menang Bastanta Tengku M. Fauzi Tengku M. Fauzi Tengku Muhammad Fauzi Tiji, Widjaya Taufik Tiji, Wijaya Taufik Tim Lions Club Medan Angkasa Tobing, Paul S. M. L. Urip Harahap Vandem Samuel Purba Vitrilina Hutabarat Vivian Vivian Widjaya Taufik Tiji Wijaya, Mega Yohanna Agustina Sinaga Yosy Cinthya Eriwaty Silalahi YUNAFRI, ANDRI Zainumi, Cut M. Zuliawati, Zuliawati