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Siahaan, Jekson Martiar
Department Of Physiology, Faculty Of Medicine, Institut Kesehatan Deli Husada Deli Tua, Indonesia
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A Hubungan Indeks Massa Tubuh (IMT) dan Lingkar Pinggang terhadap Ketahanan Kardiorespirasi pada Siswa SMA Methodist 1 Medan, Sumatera Utara Tahun 2023–2024.: HUBUNGAN INDEKS MASSA TUBUH (IMT) DAN LINGKAR PINGGANG TERHADAP KETAHANAN KARDIORESPIRASI PADA SISWA SMA METHODIST 1 MEDAN SUMATERA UTARA 2023-2024 Jeremia Simanjuntak; Suryati Sinurat; Alexander Parlindungan Marpaung; Menang Bastanta Tarigan; Jekson Martiar Siahaan
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

ABSTRACT Currently, modern life, especially in urban areas, promotes an instant consumption lifestyle, particularly among teenagers. With technological advancements, teenagers can easily order fast food through delivery apps, making fast food a common choice. In addition to fast food, school snacks are also highly favored by teenagers. This excessive consumption pattern, if sustained over time, can lead to fat accumulation that affects body mass index (BMI) and waist circumference. According to the 2019 health profile, 35.4% of teenagers experience obesity, with the highest prevalence in urban areas at 25.1%. Excess fat accumulation puts pressure on cardiorespiratory function, reducing lung capacity as reflected in VO2Max or cardiorespiratory endurance. This decline in cardiorespiratory endurance significantly affects a person's quality of life, causing them to feel fatigued easily and limiting their ability to engage in prolonged physical activities.Conclusion: There is a significant relationship between body mass index and waist circumference on cardiorespiratory endurance among students of Methodist 1 High School, Medan, North Sumatra..
Factors Associated with Tuberculosis in Deli Serdang, North Sumatera Fahmi Syahputra; Rudolf S. Parhusip; Jekson Martiar Siahaan
Journal of Epidemiology and Public Health Vol. 4 No. 1 (2019)
Publisher : Masters Program in Public Health

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Background: Tuberculosis (TB) is still a major public health problem in most developing countries and its incidence is rising in many developed countries. This study aimed to examine factors associated with tuberculosis in Deli Serdang, North SumateraSubjects and Method: This was a cross-sectional study conducted in Deli Serdang, North Sumatera. A sample of 190 study subjects was selected for this study comprising of 95 TB patients and 95 non-TB patients. The dependent variable was tuberculosis. The independent variables were sex, education, BCG immunization, smoking, nutritional status, and dwelling density. Data on TB status were taken from medical record. The other variables were measured by questionnaire. The data were analyzed by a multiple logistic regression.Results: The risk of TB decreased with female sex (OR= 0.33; 95% CI= 0.11 to 0.98; p= 0.046). The risk of TB increased with low education (OR= 8.47; 95% CI= 3.01 to 23.80; p<0.001), had no BCG immunization (OR= 8.86; 95% CI= 3.28 to 23.94; p<0.001), smoking (OR 6.69; 95% CI= 2.20 to 20.38; p=0.001), high dwelling density (OR= 10.35; 95% CI= 4.06 to 26.41; p<0.001), and poor nutritional status (OR= 3.44; 95% CI= 0.85 to 14.03; p= 0.085).Conclusion: The risk of TB decreases with female sex, but increases with low education, had no BCG immunization, smoking, high dwelling density, and poor nutritional status.Keywords: Tuberculosis, sex, BCG immunization, dwelling density, nutritional statusCorrespondence:
Determinants of Acute Respiratory Infection in Children Under Five in Simalingkar, Medan, North Sumatera Lasma Maria; Maestro Simanjuntak; Thomas Silangit; Jekson Martiar Siahaan
Journal of Epidemiology and Public Health Vol. 5 No. 1 (2020)
Publisher : Masters Program in Public Health

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Abstract

Background: Acute Respiratory Infection (ARI) is still one of the health problems in developed and developing countries including Indonesia. ARI is the most common disease in outpatients in North Sumatra, especially in Medan. This study aims to find out about the factors that influence ARI in toddlers in Sima
Efektivitas Gummy Candy Nanosimplisia Bonggol Nanas (Ananas comosus) Terhadap Jamur Candida albicans Juli Yosa Mega; Jekson Martiar Siahaan; Sofia Rahmi; Novarianti Marbun
BEST Journal (Biology Education, Sains and Technology) Vol 9, No 1 (2026): Juni 2026
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v9i1.14192

Abstract

Infeksi jamur yang disebabkan oleh Candida albicans masih menjadi salah satu masalah kesehatan yang sering ditemukan di masyarakat. Penggunaan obat antijamur sintetik dalam jangka panjang dapat menimbulkan efek samping dan resistensi sehingga diperlukan alternatif pengobatan berbasis bahan alam. Bonggol nanas (Ananas comosus) diketahui mengandung senyawa bioaktif seperti bromelain, flavonoid, tannin, dan fenolik yang berpotensi sebagai antijamur. Penelitian ini bertujuan untuk mengetahui efektivitas gummy candy nanosimplisia bonggol nanas terhadap pertumbuhan Candida albicans serta mengevaluasi karakteristik fisik dan nanopartikel sediaan. Penelitian ini merupakan penelitian eksperimental laboratorium menggunakan rancangan post test only control group design. Bonggol nanas diekstraksi menggunakan metode maserasi dengan pelarut etanol 96%, kemudian dibuat nanosimplisia menggunakan metode ultrasonikasi. Nanosimplisia diformulasikan dalam bentuk gummy candy dengan variasi konsentrasi F0 (tanpa nanosimplisia), F1 (5%), F2 (7,5%), dan F3 (10%). Evaluasi sediaan meliputi organoleptik, pH, keseragaman bobot, kadar air, tekstur, stabilitas, ukuran partikel, zeta potensial, dan indeks polidispersi (PDI). Aktivitas antijamur diuji menggunakan metode difusi sumuran terhadap Candida albicans. Hasil penelitian menunjukkan bahwa seluruh formula memiliki karakteristik fisik yang baik dan stabil selama penyimpanan 30 hari. Formula F3 menghasilkan ukuran partikel terkecil yaitu 142,8 ± 5,1 nm, nilai zeta potensial -34,5 ± 1,1 mV, dan nilai PDI 0,214 ± 0,01 yang menunjukkan sistem nanopartikel stabil dan homogen. Uji aktivitas antijamur menunjukkan bahwa formula F3 memiliki aktivitas tertinggi dengan diameter zona hambat sebesar 21,37 ± 0,62 mm yang termasuk kategori kuat dan mendekati kontrol positif Nystatin sebesar 24,63 ± 0,55 mm. Berdasarkan hasil penelitian dapat disimpulkan bahwa gummy candy nanosimplisia bonggol nanas berpotensi dikembangkan sebagai sediaan antijamur herbal terhadap Candida albicans
Efek Ekstrak Etanol Daun Kipahit (Tithonia Diversifolia) Terhadap Kadar Gula Darah, Malondialdehide, Profil Lipid, HMG-COA pada Tikus Putih Galur Wistar (Rattus Norvegicus) yang Diinduksi Streptozotocin (STZ) dan High Fatty Diet (HFD) Rosmauli Napitupulu; Jekson Siahaan; Endy Endy
Jurnal Locus Penelitian dan Pengabdian Vol. 5 No. 7 (2026): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v5i7.5794

Abstract

Diabetes melitus tipe 2 (DMT2) merupakan penyakit metabolik kronis dengan prevalensi global yang terus meningkat. Tithonia diversifolia (kipahit) mengandung senyawa bioaktif yang berpotensi sebagai antidiabetes. Penelitian ini bertujuan menganalisis efek ekstrak etanol daun kipahit terhadap gula darah, antioksidan (MDA), profil lipid, dan HMG-CoA pada tikus Wistar yang diinduksi STZ dan HFD. Penelitian eksperimental laboratorium dengan rancangan post-test only controlled group menggunakan 36 tikus dibagi menjadi 6 kelompok: kontrol normal, kontrol negatif (STZ+HFD), kontrol positif (STZ+HFD+metformin), dan 3 kelompok perlakuan dengan dosis 100, 150, dan 200 mg/kgBB. Parameter yang diukur meliputi berat badan, gula darah, MDA, profil lipid, dan HMG-CoA. Hasil menunjukkan efek signifikan: penurunan MDA (p=0,003) terutama pada dosis 100 mg/kgBB (8,91±3,90 µmol/L) dibanding kontrol diabetes (94,66±35,06 µmol/L); proteksi berat badan (p<0,001); efek hipoglikemik dengan dosis 200 mg/kgBB terbaik (112,17±13,50 mg/dL); perbaikan profil lipid dengan penurunan trigliserida (p=0,028), peningkatan HDL (p=0,042), dan penurunan LDL (p=0,028); tidak ada efek signifikan pada HMG-CoA (p=0,524). Molecular docking menunjukkan senyawa aktif memiliki afinitas pengikatan superior terhadap HMG-CoA dan leptin dibanding metformin. Tidak ada dosis tunggal optimal untuk semua parameter: dosis 100 mg/kgBB untuk antioksidan dan berat badan, 150 mg/kgBB untuk profil lipid, dan 200 mg/kgBB untuk kontrol glikemik. Hasil ini mendukung daun kipahit sebagai terapi komplementer potensial untuk pengelolaan diabetes melitus.
POTENSI LABU SIAM SEBAGAI ANALGETIK Jadeny Sinatra; Jekson M. Siahaan
Majalah Ilmiah METHODA Vol. 14 No. 1 (2024): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol14No1.pp8-16

Abstract

Pain is an unpleasant emotional sensation. Pain can begin after inflammation and/or after tissue damage. The use of analgesic or anti-pain drugs so far has undesirable side effects, so people have begun to look for alternative traditional medicines as a substitute. One of the plants that can be used as an alternative medicine for analgesics is chayote (S. edule). The purpose of this review is to provide information about chayote as an analgesic. This study focused on reviewing articles on experimental studies conducted in vivo and its bioactive components.
Co-Authors Ade Setiowati Adrian Khu Agnes Imelda Manurung Ahmad Abiyyu Muda Lubis Ainun, Nur Azizah Alex M. T. LumbanRaja Alexander P. Marpaung Alexander P. Marpaung Alexander Parlindungan Marpaung Alprindo Sembiring Meliala Amril Purba Ardinata, Dedi - Ariani, Peny Ariescha, Putri Ayu Yessy Aritonang, Sriulina Atmawidjaja, Rachmat Atta Celine Nouli Saruksuk Bahtera Bindavid Purba Barukh Saro Talenta Zebua Batara Simangunsong Binarwan Halim Binarwan Halim Br Purba, Debora May Sary Br. T. Tambun, Gita Sradha Budi Darmanta Sembiring Butar-Butar, Harry Chalil, M. Jalaluddin A. Cristian Marito Siregar Damanik, Irene Daulay, Agus Husein Dearni Damanik Diani Nazma Dina R. Purba Dina Riani Purba Dinillah Salsabila Bahar Dwi Lunarta Doderina Siahaan Efbertias Sitorus Efrata Sembiring Eka Samuel P. Hutasoit Elmina Tampubolon Elvana, Ayu Endy Endy Endy Juli Anto endyjulianto endyjulianto Enney Evirosa J. Simanjuntak Evirosa J. Simanjuntak Fadinie, Wulan FAHDI, FIRDAUS Fahmi Syahputra Fauzi, Tengku M. Fauzi, Tengku Muhammad Firdaus Fahdi Fithri Handayani Frengky S. Manullang Frengky S. Manullang Goklas Panjaitan Grace Stefani Christanto Guntur Perangin-angin Hadyanto L Hadyanto Lim Hakim, Enggrek Pelita Hambali Hambali Hamdi, Tasrif Hanjaya Hanjaya Hanjaya, Hanjaya Harahap, Nurul Dahlia Hariati Data Hariati Hariati Harry Butar-butar Harry Butar-butar Helen Debora Napitupulu Hendrika A. Silitonga Hendrika Silitonga Horas Rajagukguk Horas Rajagukguk Hutabarat, Vitrilina Hutagalung, Mangatas Halomoan Parluhutan Hutagalung, Sanggam B. Hutagalung, Sanggam Bangun Hutapea, Kenal P. Hutasoit, Eka Samuel P. Iffan Fuady Harahap Ilyas, Syaffrudin Imelda Montes Monika Simanungkalit Inda M. H. Sinaga Inda M.H. Sinaga Indra Satrio Anantha Hasugian Irene R. T. Damanik Irene R. T. Damanik Irene Ruminta Tua Damanik Irfan Hamdani, Irfan Irina, Sinta Ivonne R.V.O. Situmeang Ivonne R.V.O. Situmeang Jadeny Sinarta Jadeny Sinatra Jadeny Sinatra Jan Pieter Sihombing Jenita Oktavia Panjaitan Jeremia Simanjuntak Jones Simatupang Joslouis Hutagaol Joslouis Hutagaol Julenda I. Sebayang Julenda I. Sebayang Juli Jamnasi Juli Jamnasi Juli Jamnasi Juli Y. Mega Juli Yosa Mega Juliyanti Tarigan Juliyanti Tarigan Karen Natalie S. Karen Natalie S. kenvin rusli Kezia Stephanie S. Kezia Stephanie S. Lamtiar, Rebecca Rumesty Lasma Maria Laura Octavina Siagian Lesmana Syahrir Lesmana Syahrir, Lesmana Lubis, Andriamuri P. Maesstro B. U. Simanjuntak Maesstro B. U. Simanjuntak Maestro B. U. Simanjuntak Maestro Simanjuntak Maludin Panjaitan Manik, Widya Dayanti Feronika Manullang, Frengky S. Maria, Lasma Marolop Hutapea Marolop Hutapea Mega, Juli Yosa Mei Jayanti Siregar Meilinda, Selvia Melissa Angie Menang Bastanta Tarigan Menang Bastanta Tarigan Momot, Estela Salomina Mutiara Dwi Yanti Nababan, Manaor Bismar Posman Nababan, Titus Imanuel Nadapdap, Thomson P. Nainggolan, Ranatha NH Nainggolan, Serevina Napitupulu, Helen Debora Natalie S., Karen Nova Feronika Rajagukguk Nova Feronika Rajagukguk Novarianti Marbun Noviola Sari Kusuma Sagala Novrina Situmorang Nur Mala Sari Nurmala Sari Nurul Aini Siagian Nurwijayanti Owen Sitompul Owen Sitompul Pakpahan, Edwin Anto Panataria, Lince Romauli Panjaitan, Bintang Andika Panjaitan, Goklas Pasaribu, Sumihar Paul S. M. L. Tobing Paul Saut Marganda L Tobing Pengarapen Tarigan Peny Ariani Peny Ariani Pratiwi, Ade Dwi Putri C. Eyanoer Putri Chairani Eyanoer Putri Chairani Eyanoer, Putri Chairani Rahmi, Sofia Ratih Praseti Yanti Ria Oktavia Ricke Loesnihari Rifqi Aufan Rika Puspita Sari Rimbun, Surjadi Ronald T. H. Tambunan Ronald T. H. Tambunan Ronald T. H. Tambunan, Ronald T.H. Tambunan Rosmauli Napitupulu Rostiodertina Girsang Rostiodertina Girsang Rudolf S. Parhusip Sagala, Daniela Salamon, Yuda Monang Salomo G. U. Simanjuntak Salomo Garda Utama Simanjuntak Sanggam B Hutagalung Sanggam B. Hutagalung Sanggam B. Hutagalung SARAGIH, MEYLIN KRISTINA Sari, Nur Mala Sembiring, Bob Agustinus Sembiring, Budi Darmanta Sembiring, Mikael Siagian, Laura Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sihombing, Amordekhai Imvan Parlindungan Sihombing, Parsaoran Sihotang, Ruth Wydia Wati Sijabat, Kesia Silaen, Ester L. R. Silalahi, Veraci Silangit, Thomas Silitonga, Hendrika Adriana Silitonga, Hendrika Andriana Silitonga, Hendrika Andriani Simangunsong, Batara Simanjuntak , Salomo G. U. Simanjuntak, Jeremia Simanjuntak, Maestro Simanjuntak, Maestro Bina Utama Simanjuntak, Pantas Simanjuntak, Salomo Garda Utama Simanjuntak, Salomo Garda Utama Simatupang, Aditia Erick Cantona Simbolon, Boyke M. Sinatra, Jadeny Sinurat, Suryati Sirait, Kilian Sitepu, John Frans Siti Normi Sitompul, Michael Sabatino Sitorus, Friska Ernita Sitorus, Ragnar Oktavianus Situngkir, Jesica Damayanti Sofia Rahmi Sofia Rahmi Stephanie S., Kezia Steven Tjendra Sucipto Sucipto Sucipto Sucipto Sumihar MR Pasaribu Surjadi Rimbun Surjadi Rimbun Surjani, Lylys Suryati Sinurat Suryati Sinurat Syafruddin Ilyas Syafruddin Ilyas Syafruddin Ilyas Tambunan, Nur Lela E. Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tampubolon, Ruth Septianna Br. Tanjung, Qodri F. Tarigan, Gracecilia Tarigan, Juliyanti Tarigan, Leonardo Tarigan, Menang B Tarigan, Menang Bastanta Tengku M. Fauzi Tengku M. Fauzi Tengku Muhammad Fauzi Tetty Junita Purba Tetty Junita Purba Thomas Silangit Tiara Larasati Tiji, Widjaya Taufik Tim Lions Club Medan Angkasa Tim Lions Club Medan Angkasa Tobing, Paul S. M. L. Urip Harahap Vandem Samuel Purba Vivian Vivian Widjaya Taufik Tiji Widjaya Taufik Tiji Wijaya Taufik Tiji Wijaya, Mega Yohanna Agustina Sinaga Yosy Cinthya Eriwaty Silalahi YUNAFRI, ANDRI Zahirman, Zahirman Zainumi, Cut M. Zuliawati, Zuliawati