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Journal : Tropical Animal Science Journal

Antidiabetic and Hypolipidemic Potential of Cow’s Milk Yogurt with the Addition of Herbal Extracts in Diabetic Rats Pazra, D. F.; Purwanti, M.; Handayani, K. S.; Wahyuningsih; Wahyuwardani, S.
Tropical Animal Science Journal Vol. 46 No. 4 (2023): Tropical Animal Science Journal
Publisher : Faculty of Animal Science, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5398/tasj.2023.46.4.494

Abstract

Yogurt, with the addition of herbal ingredients can add efficacy and value of its benefits. Several studies have proven that cinnamon, aloe vera, and fenugreek seeds have properties as antidiabetic and hypolipidemic. The purpose of this study was to evaluate the antidiabetic and hypolipidemic potential of yogurt with the addition of a combination of two or three types of herbal extracts, such as cinnamon, fenugreek seeds, and aloe vera, in diabetic rats. Diabetic rats were divided into six groups and given treatment for 21 days. Rats’ blood was taken to test blood glucose levels using glucometers, insulin with the ELISA method, blood lipid profiles, and kidney and liver functions using a chemistry analyzer. The data were statistically analyzed using one-way ANOVA followed by the Duncan test. The results showed that yogurt added with several combinations of herbal extracts such as cinnamon, aloe vera, and fenugreek seeds (III, IV, V, and VI) could significantly reduce blood glucose levels, increase insulin levels, improve lipid profiles, and improve kidney and liver functions in diabetic rats, as well as commercial administration of glibenclamide (II). Diabetic rats given yogurt with the addition of a combination of 3 herbal extracts (VI) and a combination of 2 herbal extracts (cinnamon +fenugreek seeds) (V) of 1% each showed better antidiabetic and hypolipidemic performances compared to the other groups (III, and IV). The combination of yogurt with some herbal extracts can add efficacy and value to the benefits of yogurt as a functional drink.
The Metagenomic Analysis of the Pig Digestive System Microbiome as a Basis for Disease Control on Farming in Tangerang District, Indonesia Endrakasih, E.; Pazra, D. F.; Wahyuningsih
Tropical Animal Science Journal Vol. 47 No. 3 (2024): Tropical Animal Science Journal
Publisher : Faculty of Animal Science, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5398/tasj.2024.47.3.280

Abstract

Characteristics of microbiome of the pig’s digestive tract play an important role in the animal’s physiology, including metabolism, nutrient processing, the body’s immune response, and disease resistance. This study aims to analyze the abundance and diversity of microorganisms (pathogenic and non-pathogenic) from the digestive system of pigs on farms in Tangerang District. The samples used in this research were pig feces from 43 pig farms in Tangerang District. Then DNA extraction was carried out using the Zymo Quick-DNA Fecal/Soil Microbe Kit according to manufacturing procedures. Sequencing was performed using an MGI DNBSEQ-G50 machine with a DNBSEQ-G50RS High-throughput sequencing set (FCL PE100) according to manufacturing procedures. The quality of fastq files was evaluated with FastQC. Taxonomic classification of the processed sequences was performed using Diamond, followed by MEGAN6. The microbiome of the pig’s digestive system was dominated by bacteria (85%) with the taxonomic profile at the phylum level of abundance dominated by Firmicutes (84.46%) and Bacteroidetes (9.11%). Abundance at the genus level was dominated by Enterococcus (20.44%) and Clostridium (10.31%), and at the species level it was dominated by Escherichia coli (4.92%) and Levilactobacillus brevis (4.84%). There were 10 species of pathogenic bacteria detected, with E. coli showing the highest relative abundance (4.92%). Changes in the gut microbiome play an important role in the physiology of animal health and disease. In addition, the pathogenic bacteria detected not only affect the health and productivity of pigs but also have the potential to threaten public health.
Co-Authors Adam, Fikri Ahmad Setiawan Nuraya Allania Hanung Putri Sekar Ningrum ANAFRIN YUGISTYOWATI Anggraeni, Windi Ariesti Anik Indriono Anwar Hakim Derajat Ardiana Priharwanti Arif Sabta Aji Arifatul Khoirunissak Arinda Deswanti Pertiwi Arini, Naura Nazhyrah Asfar, Akbar Asngadi Asngadi Asniwati Astuti, Ni Luh Putu Wiardani Azzahra, Meila Bilal, M. Ahmad Bima Suryantara Brajakson Siokal Chalimah Darsih Dedy Richi Rizaldy Despita Pramesti, Despita Dessy Nourma Siska Savitri Devi Cintia Kasimbara Devi Cintia Kasimbara Dhenggo, Klaris Fransiska Diah Warastuti Dina Martha Fitri Dwi Retnaningsih Elimawaty Rombe Endrakasih, E. Erik Kartiko Fadilah, Resmi Afifah Fahriansyah, Ridho Farreza Febriyanti, Rinda Febriyanti Feny Yulita Fii Ahsani , Riska Fitri, Mohamad Garciano Bisuk Nathaniel Simanjuntak Gusti Andika Yudhistira Handayani, K. S. Hanik Amaria Harmaini Hasmiati Hidayat, Irwin Hutami, Safrinita Tri Jhon, Yoseph Jihan Abrori Jumrah Kadir, Muhammad Kadir Karim, Dhifa Latifah Kartini Rahman Nisa Kerstan Nathanael Djaja Kodrat Eko Putro Setiawan Lumban Gaol, Juan Oscar Maulana Magetsari, Ovy Noviati Nuraini Marni Marni Marni, Marni Maruli Taufandas Masita, Syarifah Maskuri Sutomo Maula, Muhammad Fatih Izzul Mayaputri, Velmi Megawati Mia Dwi Mona Adriana Patriyasa Muhamad Ikhsan Mustopa Muhammad langlang Tahta Raharja Muhanna, Arqan Doni Muis Kasim, Abdullah Mulyanugroho, Ade Isna Munawaroh, Siti Raudah Murtiningsih, Retno Sari MUSLIMIN Muzakir Nadia Nur Azizah Nafilla, Nur Nazwa Silva Fauziah Nindya Kirana Putri Sandy Ningsih, Winda Nudiatulhuda Mangun Nur Amanda Nuraeni Nurhadyati Nurhasanah Nurhayati Nurinda, Eva Nurunniyah, Siti Nuwa, Gisela Pancanugraha, Indra Pande Putu Novi Ekajayanti Pande Putu, Novi Ekajayanti Paramita, Dyah Pradnya Pazra, D. F. Petra Elti, Bernadina Pramudita Septiani PRASETYO, ERWIN Pratama, Muhammad Alif Prayogi, Ardan Wahyu Purwanti, M. Putri Ayu Lestari Putri Kurniawati, Putri Putrini, Andini Justina Qadrianti, Laeli Raden Roro Tsara Ayuninggati Rahma Laili, Deby Rahmadina Ratih Kumala Dewi Ratna Dewi Retna P.D, Teresia Ririn Krisnawati Risnawati Rizka Ayu Amalia, Rizka Ayu Rusman, Irma Sakinah Santika, I Kadek Dwi Shabilla Risty Eka Putri Sigiro, Semton Vicktor Sitti Aisyah Sondang Visiana Sihotang Sudarman Supriadi Sutanta Sya'bania, Nursina Syamsuddin Syamsul Bachri Tatik Mariyanti, Tatik Teguh Irawan Tia Yuniarsih Tri Ningsih, Wahyu V. Teguh Suharto Vina Asna Afifah Vitayanti Fattah Wahab, Isnaeni Wahyu Ernawati Wahyuningsih Wahyuningsih Wahyuwardani, S. Widiantari, Kadek Winarsih Winarsih Yati, Kristina Yuniarti Yunri merida Yustina Ananti Zul Astri