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All Journal Jurnal Surya Medika Jurnal Kreativitas PKM Jurnal Farmasi Indonesia Jurnal Informasi dan Teknologi Indonesia Berdaya Borneo Journal Of Pharmascientech Community Empowerment Jurnal Kesehatan Tambusai Iqtishaduna : Jurnal Ilmiah Mahasiswa Hukum Ekonomi Syariah Ruang Cendekia : Jurnal Pengabdian Kepada Masyarakat Journal of Nursing Invention Journal of Pharmaceutical Care and Sciences Jurnal Bakti Untuk Negeri Sains Medisina Health Research Journal of Indonesia Majalah Cendekia Mengabdi Detector: Jurnal Inovasi Riset Ilmu Kesehatan Jurnal Farmasi SYIFA Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia Midwifery Science Care Journal Journal of Pharmascience
Rina Saputri
Program Studi Sarjana Farmasi, Universitas Sari Mulia
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Potensi Antimikroba Ekstrak Etanol Kulit Luar Buah Cempedak (Artocarpus integer (Thunb.) Merr.) Rina Saputri; Ali Rakhman Hakim; Dahlia Syahrina; Fatthiya Lisyanti
Jurnal Surya Medika (JSM) Vol 5 No 1 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.188 KB) | DOI: 10.33084/jsm.v5i1.945

Abstract

The background of this research is to develop the potential of biological resources in South Kalimantan. In particular, the biological source is cempedak fruit. The use of cempedak which has been scientifically studied is the use of cempedak bark as anti-malaria. Other studies related to other parts of cempedak are still not widely used. Based on the potential possessed by cempedak bark, it is likely that other parts of cempedak also have potential as traditional medicine. This study aims to identify the content of secondary metabolites from the outer skin of cempedak fruit, analyze the potential of the outer skin of cempedak fruit as an antimicrobial and analyze the effective dose as an antimicrobial. The method used to see MIC values with liquid dilution and KBM values with solid dilution. The results of phytochemical identification showed that the ethanol extract of the outer skin of cempedak fruit contained secondary metabolites in the form of saponins, tannins, flavonoids and alkaloids which have antimicrobial potential. The results of the antimicrobial activity test showed the MIC value of the ethanol extract of cempedak fruit outer skin against Escherichia coli bacteria at a concentration of 50% and against Staphylococcus aureus at a concentration of 25%. The KBM value also shows the same value as KHM. Based on the results of the study it can be concluded that the ethanol extract of cempedak fruit outer skin has broad-spectrum antimicrobial activity.
Narrative Review: Optimasi Etanol sebagai Pelarut Senyawa Flavonoid dan Fenolik Ali Rakhman Hakim; Rina Saputri
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1641

Abstract

The use of ethanol as a solvent for secondary metabolite compounds is very widespread. Ethanol can dissolve flavonoid compounds and phenolic compounds from plants. To be able to utilize ethanol as a solvent is dependent on some factors of concentration, temperature, time, and selection of extraction methods. This study uses the method by searching scientific articles from the MDPI website database. The Ultrasound-Assisted Extraction (UAE) method is very suitable for the optimization of ethanol as a solvent. The optimal use of ethanol is in the concentration range of 50-80%, temperature conditions in the range of 40-70ºC, and the extraction time is in the range of 30 minutes - 24 hours.
Narrative Review: Implementasi Distribusi Obat yang Baik di Pedagang Besar Farmasi Mustaqimah Mustaqimah; Rina Saputri; Ali Rakhman Hakim
Jurnal Surya Medika (JSM) Vol 6 No 2 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i2.2128

Abstract

Distribution of pharmaceutical products from the pharmaceutical industry before reaching the pharmacy service point must be through wholesale. Good distribution practice methods are a set of standardized routine working methods, which ensure the quality, safety, and efficacy of pharmaceutical products remain intact from the very beginning to the end of the expiration period. Good distribution practice methods must be implemented by all wholesale in Indonesia so that wholesale operations can run effectively and efficiently. All pharmaceutical wholesalers must have standard operating procedures, personnel with integrity, and a good documentation system.
Analisis Faktor yang Berhubungan dengan Kepatuhan Pasien di Kabupaten Banjar Mustaqimah Mustaqimah; Rina Saputri; Ali Rakhman Hakim; Reny Indriyani
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2659

Abstract

Hypertension is still the most common disease in the world. South Kalimantan Province in 2018 became the province with the highest number of hypertension sufferers in Indonesia. Hypertensive patients will undergo hypertension therapy for the rest of their lives so that blood pressure can still be well controlled. Lifelong therapy can reduce patient compliance in taking hypertension drugs; this can result in failed therapeutic goals and lead to the emergence of other diseases such as myocardial infarction and others. The purpose of this study was to analyze sociodemographic factors and clinical factors that may be related to patient compliance in taking hypertension drugs in Banjar Regency. The results showed that the majority of respondents had low compliance in consuming hypertension drugs. The analysis showed that sociodemographic factors such as gender, age, occupation, and place of getting the drug and clinical factors in the form of drugs used and blood pressure control did not show a significant relationship. The education factor shows a p-value < 0.05, which indicates the education factor has a significant relationship.
Analisis Toksisitas Akut Kombinasi Captopril dengan Rebusan Daun Sirsak pada Tikus Galur Wistar Rina Saputri; Mustaqimah Mustaqimah; Ali Rakhman Hakim
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2849

Abstract

Hypertension is a degenerative disease that requires lifelong therapy. Along with the development of time, nowadays people are more interested in consuming traditional medicine, especially by using plants. In addition to consuming soursop leaf decoction, people also continue to use conventional medicine to help control hypertension. The combination of conventional medicine and traditional medicine can cause unwanted reactions if not used in the right dosage, one of which is the risk of acute toxicity. Until now there is no published data showing the acute toxicity analysis of the combination of captopril with soursop leaf decoction. The purpose of the study was to determine the maximum dose of the combination of captopril and soursop leaf decoction that could be used. The method used in this study is an advanced experimental study with a random block design using 30 test animals divided into 10 groups. The results of the acute toxicity test conducted did not show any death of the test animals within 24 hours and up to 7 days of observation in all experimental groups. The results of the physical observation test for 7 days showed that all rats were in normal condition in all experimental groups. The conclusion of this study is that the combination of captopril up to a dose of 150 mg/day (dose in humans before conversion to test animals) + soursop leaf decoction with an effective dose of 300 ml (dose in humans before conversion to test animals) did not show any death and symptoms toxicity in test animals.
Aktivitas Antioksidan Kulit Buah Cempedak (Artocarpus integer (Thunb.) Merr.) asal Kalimantan Selatan Ali Rakhman Hakim; Rina Saputri; Amanda Shelvia Savitri; Anisa Ujuldah; Fitri Sadlia
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2858

Abstract

The increasing incidence of diseases related to oxidative stress among the human population has led to an increase in the consumption of natural antioxidants in the human diet. The purpose of this study was to determine the antioxidant activity of cempedak fruit skin extract with 50% ethanol and 70% ethanol as solvents. The method used was testing of radical inhibitory activity with the DPPH method (1,1-diphenyl-picrylhydrazil) and as a positive control was vitamin C. The results of phytochemical screening were known to contain phenolics, flavonoids, and tannins. The results of the antioxidant activity of E50% obtained IC50 values of 650.07 ppm and IC50 of E70 of 1219.69 ppm. From these results, it can be concluded that the skin of the cempedak fruit does not have antioxidant activity.
LITERATURE REVIEW: HUBUNGAN KEPATUHAN KEMOTERAPI DENGAN KUALITAS HIDUP PASIEN KANKER PAYUDARA Arya Andika Saputra; Rifa'atul Mahmudah; Rina Saputri
Journal of Nursing Invention Vol 2 No 1 (2021): Journal of Nursing Invention
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.578 KB)

Abstract

Latar Belakang: Kanker disebabkan oleh pertumbuhan sel-sel jaringan yang abnormal. Kanker payudara merupakan permasalahan utama kesehatan pada kalangan wanita. Salah satu penatalaksanaan utama pada penyakit kanker yaitu kemoterapi. Proses kemoterapi harus memiliki tingkat kepatuhan tinggi agar dapat menunjang keberhasilan terapi. Keberhasilan terapi akan meningkatkan kualitas hidup pasien. Tujuan: penelitian ini untuk mengetahui tentang hubungan kepatuhan kemoterapi dengan kualitas hidup pasien kanker payudara. Metode: Penelitian ini menggunakan literature review, dalam pencarian literature bersumber dari tiga database (Pubmed, Doaj, Google Scholer), menggunakan kata kunci sesuai dengan tema. Hasil: Kepatuhan pasien kanker payudara yang menjalani kemoterapi dipengaruhi oleh tingkat stadium dan efek samping sistemik dari pengobatan. Kualitas hidup pasien kanker payudara dipengaruhi oleh banyak faktor. Kualitas hidup pasien kanker payudara dapat ditingkatkan dengan pemberian edukasi. Pasien kanker payudara yang patuh menjalani kemoterapi memiliki kualitas hidup yang baik. Kesimpulan: adanya hubungan kepatuhan menjalani kemoterapi dengan kualitas hidup pasien kanker payudara. Rekomendasi: Diterapkannya sikap kepatuhan pada pasien kanker payudara dalam menjalani kemoterapi supaya dapat meningkatkan kualitas hidup pasien. Background: Cancer is caused by the growth of abnormal tissue cells. Breast cancer is a major health problem among women. For cancer sufferers must undergo chemotherapy. In the chemotherapy process, you must have a high level of adherence in order to improve your quality of life. Aim: This study was to determine the relationship between chemotherapy adherence and quality of life in breast cancer patients. Methods: this study used a literature review, in which literature searches were sourced from three databases (Pubmed, Doaj, Google Scholer), using keywords according to the theme. Results: Surveillance of breast cancer patients undergoing chemotherapy that was constructed by the stage level and systemic side effects of treatment. The quality of life of breast cancer patients by many factors. The quality of life for breast cancer patients can be improved by providing education. Breast cancer patients who are adherent undergo chemotherapy with good quality of life. Conclusion: There is a relationship who underwent chemotherapy with the quality of life of breast cancer patients. Recommendation: the application of attitudes to breast cancer patients in chemotherapy life can improve the quality of patients.
Efektivitas Terapi Antihipertensi Pada Kasus Krisis Hipertensi di Instalasi Gawat Darurat RSUD Ulin Banjarmasin Evita Peron Yoewono; Rina Saputri; Rifa’atul Mahmudah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.502 KB)

Abstract

ABSTRACT Background: Hypertension crisis is a case of disease that often occurs, if not handled properly will cause comlication and death. This study was conducted to determine effective therapies in dealing with hypertensive crises so as to minimize the occurrence of complication and death in patients experiencing hypertensive crises Method: The research method is a prospective cohort. Data analysis using Pair T-Test and ANOVA, analytic analysis with evidence based medecine principles. Consists of 11 urgent hypertension samples and 9 emergency hypertension samples. Results: The results of the study for the case of hypertension urgency there are 6 therapeutic groups including furosemide, nicardipine, amlodipine, candesartan + amlodipine, clonidine and furosemide + nicardipine, but the therapy used is not in accordance with the guidelines but there are 2 groups of therapies that can reduce blood pressure including furosemide + nicardipine and clonidine, while for the case of emergence hypertension, there are 5 groups of therapies including nicardipine, amlodipine + nicardipine, furosemide, furosemide + candesartan + amlodipine and furosemide + candesartan + amlodipine + clonidine, the result is that nicardipine is a therapy that is in accordance with the guideline and the therapy is in accordance with the guideline and is in accordance with the guideline therapeutic target in lowering blood pressure. Conclusion: The use therapy is not in accordance with the guidelines for patients with hypertensive urgency cases, but is able to lower the patient’s blood pressure, whereas for patients with hypertensive emergencies the effective therapy is nicardipine. Keywords: Blood Pressure, Effectiveness, Hypertensive Crisis, Urgency Hypertension, Emergency Hypertension.
Aktivitas Antioksidan Dari Infusa Kelakai (Stenochlaena palustris (Burm.F) Bedd) Ali Rakhman Hakim; Amanda Shelvia Savitri; Rina Saputri
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.806 KB) | DOI: 10.33859/jpcs.v2i1.69

Abstract

Background: Kelakai (Stenochlaena palustris (Burn. F) Bedd.) Is a plant originating from Kalimantan that grows on peat soil. Objective: to determine the antioxidant activity of the leaves of kelakai (Stenochlaena palustris (Burm. F) Bedd.) made by infusion. Method: This type of research is true experimental and research method with post test only control group design. Kelakai made an infusion and then tested for antioxidant activity using the DPPH method. Results: The kelakai infusion positive contains flavonoids. Kelakai infusion has a very strong antioxidant activity at a concentration of 20 ppm with an absorbance value of 0.072 and an antioxidant activity of 86.90%. Kelakai infusion has an IC50 value of 6.4035 ppm. Conclusion: kelakai infusion positive contains flavonoid compounds and has a very strong antioxidant ability with an IC50 value of 6.4035 ppm. Keywords: antioxidants, flavonoids, infusion, kelakai
Profil Penggunaan Antibiotika di Puskesmas Hantakan dan Profil DAGUSIBU Antibiotika di Desa Hantakan dan Desa Alat Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.132 KB) | DOI: 10.33859/jpcs.v2i1.71

Abstract

Background : The used of antibiotics in Indonesia continues to increase, but not accompanied by good knowledge regarding the used of these antibiotics so that they have a high risk of causing antibiotic resistance. Objective : Knowing the profile of the use of Antibiotics in Puskesmas Hantakan and knowing the profile of DAGUSIBU antibiotics in Hantakan and Alat Villages. Method : This type of research is descriptive research with survey methods for the last 5 months from October 2020 to February 2021. The survey was also carried out directly to the respondents of the Hantakan Village RT.01 - RT.06 and in Village Alat RT.01 - RT.04. Results : The used of antibiotics at Puskesmas Hantakan is one of the top 10 drugs that are often prescribed. The type of antibiotic that is most widely prescribed is Amoxicillin. DAGUSIBU's profile on respondents shows that the majority of respondents get antibiotics from stalls, use antibiotics to treat various diseases, take antibiotics not according to intervals, stop antibiotics if they feel that conditions have improved, and still keep antibiotics in stock and dispose of antibiotics in an inappropriate way. Conclusion : Amoxicillin is a type of antibiotic that is most widely prescribed in Puskesmas Hantakan. The use of antibiotics without a doctor's prescription in Hantakan and Alat Villages is still high. The proper management of antibiotics among respondents in the Village of Hantakan and Alat was still low.
Co-Authors AA Sudharmawan, AA Adhea Martin, Muhammad Aditha Angga Pratama Agustina, Ani Ahmad Hidayat Aima Pitriya Ali Rakhman Hakim Amanah , Nurul amanah, nurul Amanda Shelvia Savitri Amanda Shelvia Savitri Amanda Shelvia Savitri Amanda Shelvia Savitri Amanda, Era Dea Anggia Puteri Anisa Ujuldah Anisa Ujuldah Annisa Fitria Anshori, Rahmat Giri Ariani, Malisa Arya Andika Saputra Arya Andika Saputra Aryzki , Saftia Aryzki, Saftia Auli Damayanti Aulia Damayanti Aulia Rahmah AYU LESTARI Az Zahra, Aulia Rahma Azhimia, Faida Belva Handira Budianor Budianor Dahlia Syahrina Darman, Aprilino Saputra Defitamira, Olvi Donaretsi, Olga Nathania Elisa, Audiya Emelia Haryanti Putri Enzelia, Yoan Evana, Nur Qomara Evita Peron Yoewono Fadhiyah Noor Anisa Fakhria Rizqina Fatthiya Lisyanti Faulina, Siti Emi Az-Zahra Fitri Sadlia Fitri Yuliana, Fitri Fitriyana, Rahma Frambudi, M. Noval Furqan, Rizqi Nur Gina Aulia Istiqomah Gumarus, Ellora Griselda Gusnianti, Elva Habibah, Nor Hairiana Kusvitasari Hariyanto, Ario Yudo Hateriah, SIti Henno, Mei Holilah, Shafira Nor Ilahiya, Salwa Nur Indriyani, Reni Jannah, Ghina Raudhatul Jelita Annisa Putri Jesika Natalia Julianti, Army Karinda, Niken Adkah Komaliya, Risyda Kurniawati, Darini Laili, Rofiatul Laurensia Yunita, Laurensia Lestari, Yayuk Puji Linda Kusumawati Lisaura, Inggrit Windy Lisda Handayani, Lisda Luthfi Luthfi, Luthfi Maharani, Silvia Atwi Maharani, Tri Anita Maharatini, Mei Eklesia Mara, Ignatius Ronaldy Martini, Made Maulani, Eka Febrianti Melviani, Melviani Miftahul Jannah Mohammad Basit, Mohammad Monica Wikklin Monica, Chindy Muhammad Riduansyah Mukti, Yusuf Anggoro Mursidah, Diana Aulia Murtiadi Awaluddin Mustaqimah Mustaqimah Muzdalifah, Nur Nasirah Asri Nastiti, Kunti Natantri, Bamikha Priskila Noor Latifah Noor, Fadhiyah Noor Nugraha, Dyan Fitri Nur Hidayah NURUL HIDAYAH Nurul Zafirah Octaviani, Via Oktavia, Regina Oktavia, Rissa Pratiwi, Sinta Puji Lestari, Yayuk Putri Vidiasari Darsono Putri, Mela Julia Qibtiyah, Mariatul Rahman, Agenia Ramadhan, Novalina Rossa Ramadhani, Alya Raudhatul Jannah, Ghina Reny Indriyani Ridho, Muhammad Jafar Rifa'atul Mahmudah Rifa'atul Mahmudah Rifa’atul Mahmudah Rifa’atul Mahmudah Risky Amelia Rohama Rohama Rohama, Rohama Romadhani, Yuliana Romika, Romika Rubina, Miranda Rustiana Rustiana Sadlia, Fitri Saftia Aryzki Saftia Aryzki Sagita, Ririn Samara, Akhmad Fadhil Saniah, Husnus Sari, Rani Normaya Sari, Rinda Intan Savitri, Amanda Shelvia Septianto, Gemilang Setia Budi Sismeri Dona Siti Malahayati Siti Mutaharah Sitti Khadijah Sri Rupaida Subhannur Rahman Sudarya, Maharani Fitria Syamsu, Erlina syifa, Nur Tambun, Madschen Sia Mei Ol Siska Selvija Taufik Kurahman Tuti Alawiyah Ujuldah, Anisa Ulpah, Nor Sipa Aulia Utomo, Yudha Vania, Risma Ananda Wardhani, Yuliana Widya Mariyana, Widya Yanti, Novita Yulida, Yulida Yustian, Alifira Adhany Yusuf Anggoro Mukti Zhafirah Ressa Azzahra Zhafirah, Nurul Zita, Syifa Nur Zulianur, Riska Ali