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Risk of Death in COVID-19 Patients with Comorbidity of Chronic Kidney Disease: Meta Analysis Rohmah, Isna Nur; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Coronavirus disease 2019 or known as COVID-19 was a disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). There are seven comorbidities that experience the most severity and death when infected with COVID-19, namely hypertension, diabetes mellitus, cardiovascular disease, chronic obstructive pulmonary disease, chronic kidney disease, cerebrovascular disease, and cancer. This study aimed to estimate the magnitude of the risk of death in COVID-19 patients with comorbid chronic kidney disease, with a meta-analysis of primary studies conducted by previous authors.Subjects and Method: This study was a systematic review and meta-analysis with the following PICO, population: COVID-19 patients. Intervention: comorbid chronic kidney disease. Compa
The Effectiveness of Ivermectin on the Risk of Mortality in COVID-19 Patients: A Meta Analysis Pamilih, Ayu Trisni; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: The Coronavirus Disease 2019 (COVID-19) has become the highest priority of global pandemic. New and repurposed drugs are being tested on mild to moderate levels of COVID-19 to help suppress transmission of the virus. Ivermectin is one of the repurposed drugs with known safety records with more than 2.5 billion doses dispensed in the past. This study aims to estimate the effectiveness of ivermectin in reducing the risk of mortality in COVID-19 patients based on the results of a number of previous similar studies.Subjects and Method: This study is a systematic review and meta-analysis. This study used secondary data in the form of data from previous study results. A systematic and comprehensive database search was carried out through several databases including: PubMed, Science Direct, Google Scholar, and Springer Link. Analysis of this study was using RevMan 5.3 software. This study used the eligibility criteria with the PICO model, populations: covid-19 patients, intervention: ivermectin administration, comparison: patients without ivermectin, outcome: mortality in COVID-19 patients. The inclusion criteria used were full paper in English and Indonesian with a randomized controlled trial, including the number of deaths, and the primary study was conducted in a hospital. The keywords used to search the database were
Effectiveness of COVID-19 Vaccine on Augmenting Antibody Level in People in the Special Region of Yogyakarta, Indonesia Budiyono, Joko; Murti, Bhisma; Tamtomo, Didik Gunawan
Journal of Epidemiology and Public Health Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.01.04

Abstract

Background: Immunity against SARS-CoV-2 is needed to prevent infection so vaccines are indeed humanity's great hope as a weapon to control COVID-19. Seroprevalence data is needed using an antibody test that estimates the percentage of DIY residents who have antibodies against SARS-CoV-2. This study aimed to determine the effectiveness of COVID-19 vaccination on enhancing antibody titers.Subjects and Method: This was a retrospective cohort study conducted in Yogyakarta, Indonesia, from 19 to 30 November 2021. The study population was people aged ≥1 year. A total of 563 study subjects was selected randomly. The dependent variable was the SARS-CoV-2 antibody titer level. The independent variables were COVID-19 vaccination status, gender, age, smoking, outdoor activities, and alcohol consumption. SARS-CoV-2 antibody level was measured using Roche's Elecsys anti-SARS-CoV-2. Other variables were collected using questionnaires. Data were analyzed using a multiple linear regression run on STATA 14.Results: The initial vaccination led to an elevation in -19 antibody titers, but it was statistically non-significant (b= 697.82; 95% CI= -720.90 to 1241.24; p= 0.603). The second vaccination resulted in a notable and statistically significant elevation of COVID-19 antibody titers (b= 1331.38; 95% CI= 802.30 to 1860.46; p <0.001).Conclusion: The second dose of the COVID-19 vaccination demonstrated significant effectiveness in boosting COVID-19 antibody titers. Keywords: COVID-19, vaccination, antibody
Effect of Tertiary Preventive Behavior on HbA1c Level, Quality of Life, and Complication Risk in Diabetes Mellitus Patients Livia, Wardhatul; Murti, Bhisma; Tamtomo, Didik Gunawan; Prasetya, Hanung
Journal of Epidemiology and Public Health Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.01.10

Abstract

Background: Type 2 diabetes mellitus (DM) is a non-communicable disease which is a source of additional severity for other diseases. This study aims to determine the effect of tertiary preventive behavior on hba1c level, quality of life (QoL), and complication risk in diabetes mellitus patients.Subjects and Method: This was a cross-sectional study conducted in Sukoharjo, Central Java, Indonesia, from October to November 2023. A total sample of 200 patients with type 2 diabetes mellitus (DM), registered in the Prolanis program, was selected through multistage random sampling. The independent variables were HbA1c levels, risk of complications, and QoL. The inde-pendent variable was tertiary preventive behavior. HbA1c levels were measured using spectrophotometer. QoL was measured using the WHOQOL questionnaire, and risk of complications using a questionnaire. Data were analyzed using the SEM model.Results: Tertiary prevention behavior significantly increased HbA1c level (b= 0.31; CI 95%= -0.45 to 0.15; p<0.001) and quality of life (b= 0.15; 95% CI= -0.15 to 0.38; p<0.001). Tertiary prevention behavior significantly reduced the risk of complications (b= -0.22; CI 95%= -0.42 to 0.02; p= 0.026). The goodness-of-fit values suggest that the structural equation model (SEM) is acceptable (p= 0.188; RMSEA=0.04; CFI=0.97, TLI=0.95; SRMR=0.05; CD= 0.07).Conclusion: Tertiary prevention behavior significantly increased HbA1c level and quality of life. Tertiary prevention behavior reduces the risk of complications in type 2 DM patients. Keywords: Diabetes mellitus, HbA1c, complications, quality of life
The Effect of Sleep Disorders on Anxiety and Depression in Health Workers: A Meta-Analysis Rohmani, Alfiana Nur; Murti, Bhisma; Tamtomo, Didik Gunawan
Journal of Epidemiology and Public Health Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.03.04

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Background: Sleep disorders are a clinical condition when a person frequently experiences problems or decreased sleep quality that can lead to anxiety and depression. The purpose of this meta-analysis is to estimate and analyze the magnitude of the influence of sleep disorders on anxiety and depression in health workers based on the results of previous similar primary studies.Subjects and Method: Meta-analysis was performed on a primary study with a cross-sectional design. The research with the PICO format is as follows. Q: Health workers. I: Sleep disturbances < 8 hours per day; C: No sleep disturbances (Enough sleep > 8 hours per day). O: Anxiety and depression. The meta-analysis study was conducted by searching for articles from databases in electronic form using Google schoolar and Pubmed. This study was conducted by researchers in November 2023 by searching and selecting research data online conducted by previous primary data researchers in Pubmed and google scholar with a research period of 2016-2023. The keywords used in the primary data search were "Mental health" OR "Anxiety" OR "Depression" AND "Sleep disturbance" AND "Health worker" OR "Healthcare". The inclusion criteria for this study are complete articles using Cross-sectional research, published years from 2013-2023. The analysis of the articles in this study uses RevMan 5.3 software.Results: The meta-analysis in this study included 7 cross-sectional studies from Hong Kong, China, Bangladesh, Saudi Arabia, the United States, and Turkey. The total sample size is 5,267 samples. The risk of anxiety caused by sleep disturbances in health workers was 1.6 times compared to health workers who did not experience sleep disturbances (aOR=1.67; CI 95%=1.05 to 2.45; p= 0.030). the risk of depression caused by sleep disturbances in health workers was 1.32 times compared to health workers who did not experience sleep disturbances (aOR=1.32; CI 95%=0.81 to 2.15; p= 0.270).Conclusion: Sleep disorders increase the risk of anxiety and depression in health workers.
Multilevel Analysis of Factors Affecting Depression Risk among the Elderly: Loneliness, Living Status, Physical Activity, Age, Gender, and Education Wicaksono, Emirza Nur; Tamtomo, Didik Gunawan; Prasetya, Hanung; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.04.11

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Background: There is still a high prevalence of depression in the elderly which is affected by loneliness, low physical activity, gender, last education, and residence status. Elderly people who live alone or have lost a life partner are more prone to depression. Although family support and public health services such as Posyandu are expected to protect against the risk of depression, there have not been many studies that have examined in depth the influence of Posyandu as a contextual factor in reducing the risk of depression in the elderly. This study aims to analyze the influence of these factors and the role of Posyandu in reducing the risk of depression.Subjects and Method: This study used a cross-sectional design conducted in 25 Posyandu Elderly in Grogol District, Sukoharjo Regency from August to September 2024. A total of 204 elderly respon-dents aged 60 years and above were selected using Stratified Random Sampling. The dependent variable in this study was depression collected using the PHQ-9 questionnaire, and loneliness was assessed by the UCLA Loneliness Scale. Other independent variables such as physical activity, gender, education, and life status were collected through structured interviews. Multilevel linear regression analysis is used to analyze the relationship between these factors and the risk of depression, taking into account the individual and contextual levels (Posyandu).Results: The average age of the respondents was 66.27 years old (Mean = 66.26, SD = 5.16), with 79.41% of them being female. Loneliness was significantly associated with an increased risk of depression (b= 0.05; CI 95%= 0.07 to 0.10; p=0.024), while living with family reduces the risk of depression (b= -6.33; CI 95%= -8.26 to -4.40; p<0.001). Physical activity did not show a significant association with depression. Gender, education level, and age are also not significant predictors of depression. Contextual speaking, posyandu has no effect as a contextual variable on the variable of depression in the Grogol sub-district (ICC=2.64%).Conclusion: Loneliness is a significant risk factor for depression in the elderly while living with family also reduces the risk of depression in the elderly.
The Relationships between Family Support, Age, and Gender with Quality of Life in Chronic Kidney Failure Patients at Dr. Moewardi Surakarta Hospital Amalia, Rizky Nur Aprilianti; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Epidemiology and Public Health Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.04.09

Abstract

Background: Chronic kidney failure (CKD) is a non-communicable disease in which kidney function begins to decline progressively in a matter of months or even years and can affect the patient's quality of life. The purpose of this study is to determine the effect of family support, gender and age on the quality of life of patients with chronic kidney failure at Dr. Moewardi Hospital Surakarta.Subjects and Method: This study used a cross-sectional design conducted at Dr. Moewardi Surakarta Hospital in June 2024. The target population of the study was 920 patients with chronic kidney failure at Dr. Moewardi Hospital Surakarta. A total of 200 study subjects were selected using simple random sampling. The dependent variables are family support, age, and gender. The independent variable is quality of life. The study instruments used were questionnaires and checklists and the data was analyzed using multiple linear regression analysis and processed using Stata 13.Results:There was a statistically significant relationship between family support and quality of life in patients with chronic kidney failure. Each increase in family support score by one unit will be followed by an improvement in the quality of life of chronic kidney failure patients by 0.31 units (b = 0.31; CI 95% = 0.42 to 0.57; p = 0.023). Statistically, there is a significant relationship between age and quality of life of patients with chronic kidney failure. Each one-year increase in age will be followed by an improvement in the quality of life of chronic kidney failure patients by 0.02 units (b = 0.02; CI 95% = 0.05 to 0.38; p = 0.012). There is a very small difference in quality of life between female and male chronic kidney failure patients. Female patients with chronic kidney failure were 0.01 years lower than men, but the difference was statistically very insignificant (b = -0.80; CI 95% = -0.51 to 0.50; p = 0.975).Conclusion: There was a positive relationship between family support and age and quality of life in patients with chronic kidney failure and there was no significant difference by gender between women and men.
Meta-Analysis: Effectiveness of Dental and Oral Health Education using Combination Method on Knowledge and Plaque Scores in Visually Impaired Childrenveness of Dental and Oral Health Education using Combination Method on Knowledge and Plaque Scores in Visually Impaired Children Widayati, Anis Nur; Tamtomo, Didik Gunawan; Ichsan, Burhannudin
Journal of Health Promotion and Behavior Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejhpb.2024.09.04.02

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Background: Dental health education is important to improve people's dental and oral health. Visually impaired children have limited vision, so they need appropriate and appropriate methods for accepting visually impaired children by maximizing the provision of education through senses other than sight in carrying out treatment and prevention efforts. This study aimed to analyze the effectiveness of combination oral health education on the oral health knowledge and plaque scores in visually impaired children. Subjects and Method: This was a meta-analysis with PICO model. Population: Visually impaired children. Intervention: dental health education ≥3 methods. Comparison: without education or <3 education methods. Outcome: oral hygiene knowledge and plaque scores. Article search was carried out using the keywords: ("dental health education" OR "oral hygiene" OR "oral health education") AND ("visually impaired children" OR "blind children") AND “randomized control trial”. Studies published between 2013-2023 from the PubMed, Elsevier, Google Scholar, and Science Direct databases were included. Standarized mean difference (SMD) from selected articles were were analyzed using the Review Manager 5.4 tool. Results: 10 RCTs from India and Indonesia were included in the meta-analysis. The use of combined education methods increased knowledge of oral hygiene compared to single education (SMD= 2.67; 95% CI= 1.05 to 4.30; p<0.001). Combined education method reduced plaque scores compared to single education (SMD= -0.82; 95% CI= -1.29 to -0.35; p<0.001). Conclusion: Combination education methods increase oral hygiene knowledge and reduce plaque scores in visually impaired children.
Meta-Analysis: Effectiveness of Health Education Based on Health Belief Model in Type 2 Diabetes Mellitus Patients Afniratri, Atika; Tamtomo, Didik Gunawan; Murti, Bhisma
Journal of Health Promotion and Behavior Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejhpb.2024.09.02.04

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Background: The effectiveness of health education based on the Health Belief Model in diabetes mellitus patients can improve diabetes mellitus prevention behavior. This study aimed to determine the effect of the application of the Health Belief Model on health education in patients with diabetes mellitus. Subjects and Method: A systematic review and meta-analysis was performed using the PRISMA guidelines and the PICO model including Population= Type 2 diabetes patients; Intervention = Education based on the Health Belief Model; Comparison= Not using an educational method based on the Health Belief Model; Outcome= Perceived vulnerability, Perceived compliance, Perceived benefits, Perceived obstacles. Articles are collected from PubMed, Science Direct, and Google Schoolar. The keywords used “Health Belief Model” AND “DM” OR “Diabetes Mellitus” AND “Type-2”. A total of 8 articles met the inclusion criteria, namely primary full text paper, randomized controlled trial study design, based on the Health Belief Model, and outcomes in the form of perceptions of vulnerability, perceived compliance, perceived benefits, perceived obstacles for the meta-analysis were then assessed using RevMan 5.3. Results: Meta-analyses from Iran, India and Turkey showed that diabetes patients who were given education had an average perceived susceptibility score 1.37 units higher than those without education (SMD= 1.37; 95% CI= 0.74 to 2.01; p= 0.050). Diabetes patients who received education or education had an average severity perception score of 0.86 units higher than those without education (SMD= 0.86; 95% CI= 0.23 to 1.48; p= 0.007). Diabetes patients who received education on average had a perceived benefit score of 1.02 units higher than those who did not receive education (SMD= 1.02; 95% CI= 0.54 to 1.50; p < 0.001). Conclusion: Education based on the health belief model is effective for increasing perceptions of vulnerability, perceptions of adherence, and perceptions of benefits in diabetes patients with type 2 diabetes mellitus.
Adherence to Direct Observed Treatment Short-Course Treatment in Tuberculosis: Application of the Health Belief Model Pusporini; Tamtomo, Didik Gunawan; Prasetya, Hanung
Journal of Health Promotion and Behavior Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejhpb.2024.09.02.06

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Background: Tuberculosis (TB) is a disease that is a public health priority, because it was the leading infectious disease killer before COVID-19 which caused more than 1.4 million deaths in 2019. Non-compliance of TB patients to undergo regular treatment can be an obstacle in achieving a cure rate. and high treatment success. This study aimed to analyze the effect of the Health Belief Model application on Direct Observed Treatment Short-Course (DOTS) treatment adherence for Tuber­culosis in Karanganyar Regency. Subjects and Method: Cross-sectional study was conducted in Karanganyar, Central Java, Indonesia. The study population was Tuberculosis patients undergoing Direct Observed Short-Course Treatment. A total of 200 Tuberculosis Patients undergoing DOTS was selected using purposive sampling. The dependent variable was DOTS compliance. The independent variable was construct of health belief model. Data were collected using a questionnaire and analyzed using a multiple logistic regression. Results: Perceived threat (b= 0.20; 95% CI= 0.06 to 0.35; p= 0.007), perceived benefit (b= 0.31; 95% CI= 0.14 – 0.49; p= 0.001), and self-efficacy (b= 0.24; 95% CI= 0.13 to 0.36; p< 0.001) significantly increased TB-DOTS compliance. Perceived barrier significantly decreased TB-DOTS compliance (b= -0.21; 95% CI= -0.31 to -0.11; p< 0.001). Conclusion: Perceived threat, perceived benefit, and self-efficacy significantly increase TB-DOTS compliance. Perceived barrier significantly decreases TB-DOTS compliance.
Co-Authors Adiansa, Rendi Adji Suwandono Afniratri, Atika Ahadiyati, Dyah Mubarokah Aisyah Nooratisya Alifiyanti Muharramah Amalia, Rizky Nur Aprilianti Aminuyati Ammutammima, Ummu Fatihah Anasulfalah, Hakim Andriani, Anisa Andriyaningtiyas, Yudi Angga Ferdianto Annisa Avelia Arief Suryono Ariwardani, Betty Nurizky Avelia, Annisa Bhisma Murti Budiarti, Esty Budiyanti Wiboworini Budiyono, Joko Burhannudin Ichsan Cahyo Setiawan Danang Ardiyanto Delfita, Tria Fora Dewi Shinta Dewi, Novita Herlita Diffah Hanim Diffah Hanim dinda khalifatulloh, Bhre diansyah Dono Indarto Eka Miftakhul Jannah, Eka Miftakhul Endang Sutisna Sulaeman Enggar Anggraeni, Enggar Faried, Faried Effendi Surono Fatony, Riska Fajar Fitriah Fitriah Haliza, Afifah Nur Hanida, Amin Nur Hanif, Ihsan Hermanu Joebagio Indriyati Oktaviano Rahayuningrum Irwan, Viola Fathia Islami, Dian Dini Karlinda Karlinda Khairiyyah, Alimah Ulfah Khairunissa, Khairunissa Khairunnisa Kun'ain, Utin Ilma Agni Kurnianingsih, Widya Larsiani, Lisa Safaah Novia Livia, Wardhatul Lourena, Crysty Maki Zamzam Mala Nurilmala Marlina, Devi Marwanto, Dwi Mayangkara, Radit H. Muchsin Doewes Mufidah, Naili Zahrotun Mufidatun, Ikhtiarisca Olifia Muhajir, Alfian Nabilla, Jihan NADIA FARAH DIBA Nia Handayani Noor Alis Setiyadi Novian Anindito Santosa Novianto, Fajar Novika, Revi Gama Hatta Nur Rahmawati, Eni Nurlia, Nazilla Ade Nurvitasari, Rahsunji Intan Pamilih, Ayu Trisni Permata, Annissa Devi Prameswari, Galuh Ayu Dyah Prasetya, Hanung Pratiwi, Danies Tunjung Pratiwi, Yeocelin Mega Prawito . Puspita, Wita Hana Puspitasari, Ratih Febrinasari Pusporini Rahardjo, Setyo Sri Rahayu, Putu Sri Rahmatika Nur Aini Ratih Puspita Febrinasari Ratna Dewi Kumalasari, Ratna Dewi Ratri, Maika RB. Soemanto Rita Adriani Benya Adriani Rofana Aghniya Rohmah, Isna Nur Rohmani, Alfiana Nur Rusdiyanti, Yunita Salamah, Siti Nafi'atus Sapja Anantanyu, Sapja Shinta Shinta Shinta Sholihah, Anisa Asri Siregar, Attila Yulaicha Advendila Siti Munawaroh Soemanto, RB Subiyanto, Achmad Arman Suciati, Ony Sukandriani Utami Sulahyuningsih, Evie Sumardiyono Sumardiyono Sutanto, Alfiani Vivi Syahbaniar, Desi Syamsiar, Syamsiar Tri Puji Pangesti Tyas, Aktif Cahyaning Uki Retno Budihastuti Ulfah Hidayati Uliyanti Uliyanti, Uliyanti Umar, Alwan Dhafi Vitri Widyaningsih Wahyudi, Anwar Wicaksono, Emirza Nur Widayati, Anis Nur Widiantoro, Reza Widyarahma, Amanda Yatty Destani Sandy Yohan Yuanta, Yohan yulia lanti retno dewi Yulia Sari Yuniarti Karunia, Yuniarti Zainal, Dwi Trisnawati