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All Journal Jurnal Media Wahana Ekonomika Jurnal Riset Kimia Jurnal Zarah al-Afkar, Journal For Islamic Studies Media Ilmu Kesehatan Pena Justisia: Media Komunikasi dan Kajian Hukum Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Jurnal Abdimas Mandiri Jurnal Informasi dan Teknologi Lisan An Nathiq : Jurnal Bahasa dan Pendidikan Bahasa Arab Al Iman: Jurnal Keislaman dan Kemasyarakatan Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Disiplin : Majalah Civitas Akademika Sekolah Tinggi Ilmu Hukum sumpah Pemuda Jurnal Sosiohumaniora Kodepena (JSK) Jurnal Kewarganegaraan JURNAL KESEHATAN: JURNAL ILMIAH MULTI SCIENCES Open Access Indonesian Journal of Medical Reviews Al-Isyrof: Jurnal Bimbingan Konseling Islam Counseling Milenial (CM) Jurnal Pengabdian Masyarakat Aufa (JPMA) Chemical Engineering Journal Storage (CEJS) Journal Ta'lim of Journal STKIP Aisyiyah Riau Counselia: Jurnal Bimbingan Konseling Pendidikan Islam Jurnal At Taujih Jurnal Indonesia Sehat (JURINSE) Jurnal Ilmiah Pengabdian dan Inovasi Indonesian Journal of Community Services Cel JURNAL PENDIDIKAN DAN KEGURUAN Journal of Sustainable Community Service Central Publisher OMNICODE Journal (Omnicompetence Community Developement Journal) Neraca: Jurnal Ekonomi, Manajemen dan Akuntansi Jurnal Armada Pendidikan PEDAMAS (Pengabdian Kepada Masyarakat) Jurnal Pengabdian Masyarakat dan Riset Pendidikan Ukhuwah : Jurnal Pengabdian Kepada Masyarakat Future Academia : The Journal of Multidisciplinary Research on Scientific and Advanced CONVERSE Journal Communication Science Journal of Indonesian Primary School Social Science and Contemporary Issues Journal Jurnal Kimia Unand JKM-Bid: Jurnal Kesehatan Masyarakat kebidanan Realism: Law Review Jurnal Pengabdian Masyarakat Kesehatan Terkini Jurnal Kesehatan Masa Depan Al Iman: Jurnal Keislaman dan Kemasyarakatan Jurnal Ilmiah Manajemen Dan Kewirausahaan
Suryati
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Journal : Jurnal Riset Kimia

 1 
Cytotoxic Potential of Compounds Isolated from Non-Polar Fractions of Sungkai Plant Leaves (Peronema canescens Jack) Against Artemia salina Leach Larvae Suryati; Irfan Afrinal; Afrizal; Rahmi Vika Ulia
Jurnal Riset Kimia Vol. 15 No. 1 (2024): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i1.655

Abstract

The sungkai plant (Peronema canescens Jack), belonging to the Lamiaceae family, is a plant that is traditionally used as medicine, including toothache, malaria, and fever medicine. In this research, isolation was carried out with vacuum liquid chromatography (VLC), solid and liquid fractions were obtained. The solid fraction was further separated using column chromatography to obtain the isolated compound as a white solid (amorphous) weighing 10 mg (melting point 140˚C-142˚C). The results of the UV spectrum data show that there are no conjugated double bonds. The results of the IR spectrum show the presence of C-H groups at wave numbers 2921,49 cm-1 and 2856,94 cm-1, C=O groups at wave numbers, C=C groups at wave numbers 1641,51 cm-1, and dimethyl germinal which is characteristic of triterpenoid compounds at wave numbers 1456.68 cm-1 and 1372.41 cm-1. Meanwhile, the isolated oil was analyzed for chemical components using GC-MS. It was discovered that there were 83 chemical compound components contained therein with 4 main compound components, namely pentadecanoic acid (16.65%), 9,12-octadecanoic acid (16.12%), propyl palmitate (7.89%), and hexadecenoic acid, methyl ester (5.59%). A cytotoxic test was carried out on both fractions using the Brine Shrimp Lethality Test (BSLT) method. The results showed that the isolated compound was non-toxic with an LC50 value of 190214.2807 mg/L and the isolated oil was very toxic with an LC50 value of 34.2452 mg/L.
Bioactivity of Red Leaf Extract of Pucuk Merah Plant (Syzygium myrtifolium Walp.) Suryati; Santoni, Adlis; Arifin, Bustanul; Aisya, Nurul; Frisky, Sintia; Aisyah, Siti
Jurnal Riset Kimia Vol. 16 No. 1 (2025): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v16i1.760

Abstract

Syzygium myrtifolium Walp. is an ornamental plant traditionally used as an herbal medicine. Ethanol extract of Syzygium myrtifolium Walp. has been reported to have activities as an antioxidant, anticancer, and antimicrobial. In this study, Syzygium myrtifolium Walp is extracted. Leaves were carried out using a multistage maceration method using methanol, ethyl acetate, and hexane solvents. Antioxidant, antimicrobial, and toxicity tests were performed, and secondary metabolite compounds, total flavonoid content, and total phenolic content were identified on red leaf extract. Total phenolic content was tested using the Folin-Ciocalteau reagent, total flavonoids with the AlCl3 reagent, antioxidants with the DPPH method, antimicrobial using the disc diffusion method, and toxicity tested using the BSLT method. The result showed that Syzygium myrtifolium Walp. Red leaf extract contained a secondary metabolite of triterpenoids, steroids, phenolics, flavonoids, alkaloids, and coumarins. The ethyl acetate and methanol extract's total phenolic and flavonoid content were 311.0520 and 420.360 mg GAE/g extract and 211.788 and 105.360 mg QE/g extract. Antioxidant activity of ethyl acetate and methanol showed that the extracts were highly antioxidant with IC50 of 19.606 and 12.0656 mg/L. The antimicrobial activity showed that the hexane extract was resistant to the bacteria Staphylococcus aureus and Propionibacterium acnes and the fungus Candida albicans. However, no inhibition zones were produced for Pseudomonas aerigunosa and Escherichia coli bacteria. The toxicity test showed that the hexane and ethyl acetate extract had strong toxic properties with LC50 of 56.65 and 16.79 mg/L, and the methanol extract was toxic with LC50 of 224.2846 mg/L.
Co-Authors AdiSamudra Adlis Santoni Afrizal Afrizal Itam Agus Salim Agusmiati Agustin, Aulia Ahyuroh Aisya, Nurul Al'adawiyah, Airabi'ah Aliza, Mefti Amyati Ana Pratiwi, Nita Andi Sofyan Anas Anita Trisiah Aqgenatry Prilly, Silvi Ardhana, Nadya Dwi Aris Setyawan Arniati Asiah Kaamilah Asmawati Atik Aryani Azima, Kgs Azizah, Tyara Nur Bardiati Ulfah Bela Janare Putra Budiman, Yusuf Unggul Bustanul Arifin Darmawan, Ardhian Indra Dasep Supriatna Dedi Febry Rachman Dewi Sartika Dian Nur Adkahana Sari Didit Hadayanti, Didit Dina Sri Nindiati Emi Puspita Dewi Emil Salim Ermini Ermini Ermini Evi Yulianti Fadila, Reni Nur Fani Fadilah Farihah Fathasha Aulia Fatiha Lubis, Rabitha Canny Feri Safriwardy Fika Aulia Frisky, Sintia Handayani, Meyga Fitri Harahap, Yanna Wari Hartika Utami Fitri Hasibuan, Ahmad Safii Hendrawani Hendy Tannady Heryati, Agustina Hosan Ica Parhati Ika Sri Haryati Imelda Imelda Saluza, Imelda Indah Permatasari Irawati Irfan Afrinal Iskandar Mubarok Judijanto, Loso Kusuma, Resin Putra Teja Kusumasari, Viantika Kuswandi Layang Sardana Lena Marianti Lesi Hertati, Lesi Lisa Ayu Padila Lukman Hakim Lutfiyah Maghfirah, Sucy Makmur, Hernanda Manalullaili Marcelina, Dona Masrullita MIFTAHUL JANNAH Mina Laili, Mahsiani Ms. Rasiah, Ms. Muhammad Innuddin Muhammad Najib Mukhlisah Muzaiyana Nadiroh Nana Citrawati Lestari Nanda Suryani Sagala Nanny Mayasari Napitupulu, Natar Fitri Natasya Dwi Putri Novi Sylvia Nufida, Bq. Asma Nur Asia Nur Asia, Nur Nur islamyati, Nur islamyati Nurlaela Oktavianto, Eka Olly Norita Tetra Pagirik, Elvi Phyta Rahima Prakatika, Bastiani Pratiwi, Indah Putri Purnama, Yati Putra, Belajanare Putra, Phito Bahari Putri, Nadian Raden Roro Dinul Qoyyimah Rahayu, Puput Sri Rahma Dona Rahmah, Juanita Rahmi Vika Ulia Reni Nur Fadila Rida Jelita Rifi Iron Akhfifni Ris Akril Nurimansjah Riska Deri Rizka Mulyawan Rohid Sanjaya Rustia, Winda Sahriani, Henny SARI, DIAN NUR ADKHANA Sarni Anggoro Selvia Assoburu Seriani Annisa Setiawan Sinaga, Joel Setiawati Setyaningrum, Niken Setyawati , Wiwit Setyorini, Andri Shepta Wijaya Simamora, Asnil Adli Sinurat, Serepita Siti Aisyah Siti Maria Ulfa Siti Nur Hidayah Siti Nur Hidayah, Siti Nur Sri Astuti Sri Hertimi Sri Nur Hartiningsih SRI RAHAYU Suhenti Sulhatun Sumaina Duku Suswanti Sutartiah, Farliana Syaflita, Dina Syarifah Aini Teguh Anindito, Teguh Teja Kusuma, Resin Putra Terttiaavini Utami Fitri, Hartika Vera Prameswari Viantika Kusumasari Waruwu, Alfred Tani Wati, Widiana Welensi, Harteti Winda Hardani Wulandatika, Darmayanti Yadi Sutikno Yanna Wari Harahap Yaolanda Rizqi Agustina Yeni Isnaeni Yusran Khery Zainuddin Ginting zebua, winra