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Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Etanol Daun Salam (Syzygium  polyanthum) terhadap Bakteri Pseudomonas aeruginosa Maria Canny Astuti Gea; Muhammad Yunus; Razoki
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2026): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v2i1.181

Abstract

Infeksi bakteri masih menjadi permasalahan kesehatan yang banyak ditemukan, khususnya yang disebabkan oleh Pseudomonas aeruginosa. Daun salam (Syzygium polyanthum) diketahui mengandung senyawa aktif seperti flavonoid, tanin, alkaloid, saponin, dan minyak atsiri yang berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk memformulasikan sediaan gel ekstrak etanol daun salam serta mengevaluasi aktivitas antibakteri dan sifat fisiknya. Metode penelitian yang digunakan adalah eksperimen laboratorium dengan variasi konsentrasi ekstrak sebesar 2,5%, 5%, dan 10%. Uji aktivitas antibakteri dilakukan menggunakan metode difusi cakram terhadap bakteri Pseudomonas aeruginosa. Evaluasi sediaan gel meliputi uji organoleptis, homogenitas, pH, daya sebar, dan viskositas. Hasil penelitian menunjukkan bahwa seluruh konsentrasi gel ekstrak etanol daun salam memiliki aktivitas antibakteri yang ditandai dengan terbentuknya zona hambat pada kedua bakteri uji, dengan konsentrasi 10% menghasilkan daya hambat terbesar. Hasil evaluasi fisik menunjukkan bahwa seluruh sediaan gel memenuhi persyaratan farmasi, dengan pH berada pada rentang pH kulit, sifat homogen, daya sebar yang baik, serta viskositas yang masih dapat diterima. Berdasarkan hasil tersebut, dapat disimpulkan bahwa gel ekstrak etanol daun salam berpotensi dikembangkan sebagai sediaan topikal antibakteri terhadap Pseudomonas aeruginosa.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Daun Sirsak (Annona Muricata L.) terhadap Bakteri Pseudomonas Aeruginosa Cristin Natali Rouli; Muhammad Yunus; Asyrun Alkhairi Lubis
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2090

Abstract

Soursop leaves (Annona muricata L.) are known to contain secondary metabolites such as alkaloids, flavonoids, tannins, saponins, and polyphenols, which have antibacterial potential. This study aimed to formulate soursop leaf extract into a gel dosage form and to evaluate its antibacterial activity against Pseudomonas aeruginosa. This research was conducted as an experimental laboratory study. Soursop leaf extract was obtained using the maceration method with 96% ethanol as the solvent and then formulated into gel preparations with extract concentrations of 5%, 10%, and 15%. Physical evaluation of the gel preparations included organoleptic test, homogeneity, pH, spreadability, and viscosity. Antibacterial activity was evaluated using the well diffusion method on Nutrient Agar medium. The results showed that all gel formulations met the physical requirements for topical preparations. The antibacterial activity test demonstrated that the soursop leaf extract gel inhibited the growth of Pseudomonas aeruginosa, with the 15% concentration producing the largest inhibition zone of 10 mm compared to other concentrations. In conclusion, soursop leaf extract gel has potential to be developed as a topical antibacterial agent against Pseudomonas aeruginosa.
STRATEGY OF INTEGRATION OF DAYAH SALAFIYAH CURRICULUM AND FORMAL DINIYAH EDUCATION (PDF) IN IMPROVING STUDENTS' COMPETENCIES AT DAYAH BABUSSALAM AL HANAFIYYAH Muhammad Sariyulis; Muhammad Yunus; Yusnaini
International Journal of Social Science, Educational, Economics, Agriculture Research and Technology (IJSET) Vol. 4 No. 11 (2025): OCTOBER
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.18797521

Abstract

This study aims to comprehensively describe and analyze the design and implementation strategies for integrating the Salafiyah Dayah curriculum and Formal Diniyah Education (PDF) at Dayah Babussalam Al Hanafiyah. In line with the demands of formal recognition and globalization, traditional educational institutions such as dayah are faced with the challenge of adapting without sacrificing their Islamic identity. Dayah Babussalam Al Hanafiyah has taken a strategic policy by implementing the PDF program since 2015 to integrate the epistemology of tafaqquh fiddin with national curriculum standards. This study employed a qualitative approach with a descriptive-analytical design. Data were collected through participant observation, in-depth interviews with the dayah leadership, the head of the PDF, the teaching staff, and students, as well as a curriculum documentation study. Data analysis was conducted interactively through data reduction, data presentation, and conclusion drawing. The research results show that the curriculum integration design strategy was implemented through a collaborative planning and strategic alignment approach involving various stakeholders to formulate a bi-disciplinary curriculum. The integration model implemented encompasses four main pathways: interdisciplinary-substantive (linking science with theological concepts), structural-organizational (implementing a dual schedule system), technological-convergent (using digital media), and affective through the hidden curriculum (internalizing values ​​through daily worship traditions). The implementation of this strategy is supported by visionary leadership that combines Salafiyah values ​​with modern management based on the principles of shura, amanah, and itqan. Furthermore, the effectiveness of this integration has been proven to have a significant impact on improving the holistic competence of students. Based on the competency dimension, students showed improvements in aspects of motivation and self-concept through pride in religious-academic identity, mastery of dual knowledge (yellow books and science), and 21st-century skills including critical thinking, communication, and collaboration through mubahatsah forums. In terms of character, this integration strengthens discipline and social leadership based on Islamic values. This study concludes that the integration model at Dayah Babussalam Al Hanafiyah reflects the evolution from a mono-disciplinary system to a multi-lens educational framework that is adaptive to changing times while remaining firmly grounded in tradition. These findings contribute to the development of a practical model (best practice) for integrative curriculum management in Salafiyah Islamic boarding schools in Indonesia.
Correlation and Relevance of Islamic Economic Theory and Modern Economics Muhammad Yunus; Yadi Janwari; Ahmad Hasan Ridwan
al-Afkar, Journal For Islamic Studies Vol. 6 No. 4 (2023)
Publisher : Perkumpulan Dosen Fakultas Agama Islam Indramayu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31943/afkarjournal.v6i4.755

Abstract

This study aims to explain the correlation between economics and Islam. This research uses qualitative research, with a normative juridical approach and data collection techniques by means of literature study. The results of this study indicate that Islam is a perfect religion that regulates all aspects of human life including the economy. This is proven by the concept of welfare described in the Qur'an and Sunnah. Basically, the purpose of every human being's life is to achieve welfare, although humans interpret welfare from different perspectives. Most economic understandings assume that welfare is worldly material welfare. However, Islam defines welfare with the term Falah, which means holistic and balanced welfare between the material and spiritual dimensions. The Quran and Sunnah have taught that welfare will be achieved if humans live a life in balance between their material and spiritual lives. This is because human life does not only stop in this world, but there is still a second life that humans will face in the hereafter, and welfare will be achieved truly if humans can balance the needs of the world and the hereafter, and that is what is taught in Islamic economics
Kajian Potensi Etil Asetat Ekstrak Daun Andaliman : Total Fenol Flavonoid dan Aktivitas Uji Antioksidan Muhtamilatur Rahma; Roy Indrianto Bangar; Muhammad Yunus
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i1.7537

Abstract

Andaliman leaves (Zanthoxylum acanthopodium DC.) are a traditional plant native to North Sumatra with potential as a natural antioxidant source due to their phenolic and flavonoid compounds. This study aimed to evaluate the antioxidant potential of the ethyl acetate extract of andaliman leaves based on total phenolic content, total flavonoid content, and antioxidant activity. Extraction was carried out using the maceration method with ethyl acetate as the solvent. Total flavonoid content was determined using the AlCl₃ method with quercetin as the standard, while total phenolic content was analyzed using the Folin– Ciocalteu method with gallic acid as the standard. Antioxidant activity was evaluated using the DPPH radical scavenging assay. The results showed that the ethyl acetate extract of andaliman leaves contained 73.40 mg QE/g extract of total flavonoids (7.3%) and 148.48 mg GAE/g extract of total phenolics. The antioxidant activity test yielded an IC₅₀ value of 4,2485 µg/mL, indicating that the extract exhibits very strong antioxidant activity. The high levels of phenolic and flavonoid compounds are believed to play an important role in the radical scavenging activity observed. Based on these findings, it can be concluded that the ethyl acetate extract of andaliman leaves has strong potential to be developed as a natural antioxidant source for applications in the pharmaceutical and health fields.
Reconstruction of Maqāṣid al-Syarī‘ah fī Ḥifẓ al-Māl in Responding to Doom Spending Among Generation Z and the Implications for Family Economic Resilience Ubaidillah; Muhammad Yunus; Anita Mauliyanti; Asriadi; Bachrul Ulum; Mahmood Kooria
Al-Muamalat: Jurnal Ekonomi Syariah Vol. 13 No. 1 (2026): January
Publisher : Department of Sharia Economic Law, Faculty Sharia and Law, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/am.v13i1.53964

Abstract

Generation Z increasingly engage in doom spending driven by global economic uncertainty, diminished confidence in long-term financial security, and the pervasive influence of digital consumer culture. This behavior undermines individual financial stability and threatens family and societal economic resilience. The rising prevalence of doom spending among Generation Z has become a significant concern, particularly regarding family economic resilience. Consequently, this study reconstructs Maqāṣid al-Syarī‘ah fī Ḥifẓ al-Māl as a normative and ethical framework to address impulsive, emotion-based consumption among Generation Z couples in the digital economy. Integrating Islamic ethics, psychological coping theory, and contemporary consumption studies, this research employs a qualitative method with descriptive-analytical design. Findings indicate that doom spending negatively impacts family financial stability, exacerbates emotional stress, and conflicts with core Islamic principles including moderation (wasaṭiyyah), contentment (qanā‘ah), and prohibition of extravagance (tabżīr). The study underscores strengthening family economic resilience through digital financial literacy, open financial communication between couples, integration of Islamic consumption values, productive technology utilization, and community-based financial education. By implementing these strategies, Generation Z couples can achieve balanced financial management, enhance household resilience, and align consumption behavior with ethical and spiritual principles. This research contributes to the broader discourse on integrating Islamic value-based approaches into contemporary financial practices and offers a conceptual framework for sustainable, morally responsible household economic management.
Ventilator Weaning Through Spontaneous Breathing Trials in Children with Tetralogy of Fallot in the PICU: A Case Report Fitrian, Megah; Erika, Kadek Ayu; Muhammad Yunus
Jurnal Keperawatan Indonesia Vol 29 No 1 (2026): March
Publisher : Fakultas Ilmu Keperawatan Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.7454/jki.v29i1.1751

Abstract

Tetralogy of Fallot (TOF) is a congenital heart defect that causes chronic low oxygen levels, increased right ventricular workload, and a higher risk of complications. Weaning mechanical ventilation in patients with TOF is particularly challenging due to right ventricular dysfunction, muscle weakness, and the risk of heart failure. This study evaluates the use of a spontaneous breathing trial (SBT) strategy with pressure support ventilation (PSV) mode for mechanical ventilation weaning in pediatric patients with TOF. An observational study was conducted on a six-year-old pediatric patient with TOF and a cerebral abscess who underwent mechanical ventilation weaning using the SBT technique with PSV mode. The patient’s vital signs (heart rate and respiratory rate) and oxygen saturation were monitored 24 h before, during, and 24 h after the trial. Weaning was successfully completed within 11 h without signs of failure, such as hypoxemia or muscle fatigue. The rapid shallow breathing index measured prior to weaning was within an acceptable range. The patient’s physiological parameters remained stable throughout the process, and no Tet spells were observed. These findings suggest that SBT combined with PSV mode is a viable weaning strategy in pediatric TOF cases, particularly when a longer trial duration is used. However, because this report is based on a single case, the results should be interpreted with caution and cannot be generalized to all patients with TOF.
Co-Authors A Adjie Abdul Rosyid Minhaj Adelia Pratiwi Adinda Putri Sari Rahayu Afifah Mardiah Agus Pribadi Akhmad Ramli Alfan Zuhairi Almahfuz Alya Fadila Amahar Riadi amalia, roviatul Andi Nurul Ulum Angelia Vega Anggi Maulana Nasution Anggun Pratiwi Anita Mauliyanti Anwar Anwar Ardi Antariksa Ardiansyah Putra ARIFUDDIN Arum Setia Ningsih Arvianti Pramudita Tjandra Arya Adjie Asif, Muhammad Asriadi Astriani Natalia Br Ginting Asyrun Alkhairi Lubis Bachrul Ulum Bambang Wijanarko Bentar Putra Setiyanto Bravo Chandra Arista Cholid Shihabul Hikam Cristin Natali Rouli Daimah Wirdatus Sanaun Harahap Dandan Ramdani Daniel Happy Putra Debrina Putri Buana Desri Nurul Aeni Devin Rio Alvaro Dewa Gede Eka Setiawan Didit Panji Saputra Dimas Aji Guntoro Dinatul Adawiyah Dinda Dwi Puspita Dinda Nila Sabrina Diyanto, Rahman Djafar, Suriani Ega Yos Sanda Elsa Encep Abdul Rojak Eny Rachmawati Erdian Suntosa Erida Novriani Eril Kapri Ervinda Hardina Dwi Pratiwi Erwansyah, Erwansyah Erwanto Erwanto Esa Claudia Putri Eva Fauziah Faren Kesita Gelioni Fathurachman Samba Fauziah Finna Piska Firdaus, Riska Firkian Rinanda Fitrian, Megah George Adios Niko Glory Stevi Natasia Saragih Hariyadi Dharmawan Syahputra Harsano Jayadi Hartono, Rudi Hindri Syahputri Husnul Puad I Ketut Astawa I Mahyudi Idiar Idiar Idiar Ika Vitriasari Ilham Mujahid Irwan Putra Irwansyah Irwansyah Ismail Jecika Stefany Br Tumanggor Juanda Kadek Ayu Erika Khairil Anam Khojir Kintan Puspita Wardani Mahmood Kooria Maimun MARIA BINTANG Maria Canny Astuti Gea Masbiyanti Meidji, Icha Untari Mgarifina N Ngarifin Mikha Marcellius Saragih Mochamad Farizal Moh. Irmawan Jauhari Mohammad Wijaya.M Muhamad Osamah Fahrul Roji Muhamad Ridwan Fauzi Muhammad Akbar Muhammad al-Fain Arrafi Muhammad Amin Nasution MUHAMMAD ANWAR Muhammad Arief Nasutions Muhammad Bahit Muhammad Firdaus Muhammad Galuh Elga Romadhon Muhammad H Amrullah Muhammad Hamdan Firmanta Muhammad Ibnu Huda Muhammad Rizki Pratama Pratama Muhammad Rusdi Muhammad Sariyulis Muhammad Waspul Hasyim Muhammad Wiharto Muhammad Zulfan Muhtamilatur Rahma Mukhamad Agung Maulana Mulia Wiwin Muliawiwin Nanda Pranandita Nehru Millat Ahmad Nia Novranda Pertiwi Nor Cholis Nur Mu’min Nur Vina Yulfana Pratiwi, Lulu Puput Anggraeni Putri Diah Ayu Lestari Putri Virda Rahayu Rafiatul Latifah Rahwan, Rahwan Razoki Razoki Razoki Resky Amalia Hamka Ria Rismayati Ricky Damara Paulus Ricky Martino Ridwan, Ahmad Hasan Rina Riyanti Risma Millatul Ummah Robert Napitupulu Robiatul Adawiyah Rangkuti Rohani Lubis Rollastin, Boy Romiano Romual Yonathan Simangunsong Roy Indrianto Bangar Rullyansyah Rustiani S Salwa Firdaus Syah Sari, Syilvi Rinda Sintia Roseta Dela Siti Albadriyah Siti Hasbiah Siti Rahmah Diana Sosa Ester Kristiani Lase Sri Maya Indira Nst Stefvany Suaningrat Suarti Djafar subarjo, Subarjo Sudadi Suko Susilo Syamsul Arifin Syukri Tedy Wiraseptya Tiara Ayu Lestari Tice Lestari Ndruru Titin Suprihatin Ubaidillah Ubaidillah Ubaidillah Universitas Muhadi Setiabudi Vony Puspitasari Wiryanto Yadi Janwari Yuandani Yusnaini Zainal Ruma Zaldy Kurniawan Zidni Ilman Nafi'an Zulkarnain Umar, Zulkarnain