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Penetapan Kadar Kafein Pada Minuman Berenergi Dalam Kemasan Sachet Yang Beredar Di Pasaran Nurbaya, Siti; Supartiningsih, Supartiningsih; Hutauruk, Dumartina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Pada proses pembuatan minuman berenergi sering ditambahkan zat – zat stimulan ke dalamnya, salah satunya adalah kafein. Efek kafein dapat menghilangkan rasa kantuk, dapat memberikan kebugaran dan kesegaran pada tubuh. Kafein dapat meningkatkan tekanan darah dan peningkatan pengeluaran urin. Tujuan penelitian ini adalah untuk mengetahui kandungan kafein dalam minuman berenergi kemasan sachet yang beredar di pasaran. Penetapan kadar kafein dilakukan secara kuantitatif dengan menggunakan metode iodometri. Hasil penelitian menunjukkan bahwa seluruh sampel menggunakan kafein sebagai zat stimulannya, dimana kadar kafein dengan kode A yaitu 48,80 mg, kadar kafein dengan kode B yaitu 46,44 mg, kadar kafein dengan kode sampel C yaitu 34,73 mg dan kadar kafein dengan kode D yaitu 30,71 mg. Kesimpulan dari penelitian ini adalah bahwa semua sampel masih memenuhi peryaratan menurut Standart Nasional Indonesia (SNI) No. 01. 6684. 2002 dengan batas kadar kafein dalam minuman adalah tidak lebih dari 50 mg.
FORMULASI KRIM ANTI-AGING DARI EKSTRAK EKSTRAK ETANOL KACANG HIJAU (Phaseolus radiatus Roxb. Non-L.) Nurbaya, Siti; Br Brahmana, Nettietalia; Rejekinta Munthe, Alfian; Pangaribuan, Novalina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Background: green beans are one type of peanut that are widely consumed by communities as functional. The green nut contains a secondary metabolic compound, among them flavonoid, saponin, steroid/triterpenoid, and tannin, which are potent antioxidants.Research goals: for this study, there is an introduction to the new anti-aging activity in green beans ethanol (Phaseolus radiatus Roxb. non-L..). Research methods: this research method USES experimental methods with 5% concentration, 10%, and 15%. Then compared to the availability in the market and blanks. Some tests have been made against availability, including physical qualities of ready cream including homosexual, existing stability observations, pH, viscosity tests of volunteers, and anti-aging activities of volunteers. Results: the results from the study are the result of a stable cream test at room temperature for four weeks. Organoleptic results in Blanko’s formula and control formulas have not undergone any discoloration, changes in smell and phase separation after four-week long storage of ph cream meet good requirements in skin ph, no side effects of irritation and availability of green bean extract cream (Phaseolus radiatus Roxb. Non-L.) can demonstrate anti-aging effectiveness at 15% concentration. Conclusion: research suggests that supple green bean extract cream has an anti-aging activity.
Pengaruh Konseling Terhadap Kepatuhan Pasientuberculosis Di Puskesmas Langsa Lama Kota Langsa Nurbaya, Siti; Nuriyanti Sirait; Yanti Musyawarah
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 6 No. 1 (2024): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

The consequences of non-compliance with long-term treatment are deteriorating health and increasing treatment costs. Non-adherence of TB sufferers to treatment causes low cure rates, high mortality rates and increased recurrence and what is more fatal is the occurrence of germ resistance to several anti-tuberculosis drugs, so TB disease is very difficult to cure. The purpose of this study was to determine the effect of counseling on medication adherence. This type of research is a correlation analytic research with cross sectional method. The population in this study were TB sufferers with a sample of 35 people. The data were obtained using a questionnaire and the data were analyzed using the Chi-Square statistical test. The results showed that 1) the level of patient compliance in taking drugs in patients with tuberculosis at the Langsa Lama Health Center was in the majority with high adherence 2) the majority of counseling was given to patients with tuberculosis at the Langsa Lama Health Center in the good category, 3) there was an influence of counseling on patient compliance.
In Silico Analysis of Tea Leaf Compounds Targeting Inflammatory Pathways and Acne-Related Genes Sumarlin, La Ode; Nurbaya, Siti; Wulandari, Meyliana; Sulaiman, Syed Azhar Syed
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 2, November 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i2.46468

Abstract

Acne (Acne vulgaris) is a chronic skin disease affected by Cutibacterium acnes infection and inflammatory pathways that trigger innate immune responses, such as inflammasome activation. The expression of inflammation-related genes plays a critical role in acne pathogenesis and immune modulation. This study aims to identify compounds from tea leaves (Camellia sinensis var. assamica) that can treat acne by influencing the expression of inflammatory-related genes through in silico analysis. The GSE6475 dataset was utilized to identify differentially expressed genes (DEGs) between acne-affected and normal skin samples (each group n=6). A total of 573 DEGs were identified and mapped to the KEGG inflammatory pathway. The hub gene analysis results showed six genes, including CXCL1, STAT1, and PIK3 (adj. P-value < 0.05). These key genes were then used to cross-validate skin grouping with acne lesions and normal skin. The structure of compounds (natural products) in tea leaves (C. sinensis var. assamica) was obtained from the PubChem database, and their activity against target proteins associated with the identified key genes was predicted using the SkelSpheres descriptor and Support Vector Regression method. This quantitative structure–activity relationship (QSAR)-based machine learning approach was selected because it enables high-throughput prediction of inhibitory potential using chemical descriptors and experimentally derived bioactivity data, providing broader predictive power than conventional molecular docking or molecular dynamics, which rely mainly on structural and energetic estimations. The in-silico prediction results showed that compounds such as theobromine, assamsaponin, procyanidin, and caffeine have exhibited good predicted activity (IC₅₀ ranging from 1.125 to 1.320 μM) as potential inhibitors of the PI3K/Akt pathway, which is known to play a role in the pathogenesis of acne. 
PENGETAHUAN ORANG TUA TERHADAP PEMENUHAN GIZI SEIMBANG DALAM PENCEGAHAN STUNTING PADA BALITA DI DESA KUALA INDAH KECAMATAN SEI SUKA KABUPATEN BATU BARA Rubino, Rubino; Nurfadillah, Ainaya; Chotimah, Octavia; Nurbaya, Siti; Faridah, Siti; Fitrah, Harisa
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 9 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i9.3342-3348

Abstract

Stunting ialah keadaan gagal tumbuh yang diakibatkan rendahnya gizi pada 1000 HPK anak, yakni mulai dari dalam kandungan sampai usia 2 tahun. Problem tersebut berupa pemberian asupan gizi yang minim untuk tenggang waktu relatif lama dan mengkonsumsi makanan yang tidak selaras dengan keperluan gizi. Seorang anak dikatakan menderita stunting jika tinggi badan berada dibawah anak seumurannya. Penyebab terjadinya stunting tidak sekedar kemiskinan serta kebutuhan pangan, akan tetapi dalam bentuk pemeliharaan dan pengasuhan pada anak. Pokok utama penyebab stunting ialah rendahnya gizi ketika ibu hamil. Pencegahan stunting amat perlu dilakukan agar tidak terjadinya pertumbuhan dan perkembangan yang buruk. Salah satu cara yang dapat dilakukan untuk meminimalisir peningkatan stunting ialah pengetahuan orang tua terhadap pemenuhan gizi seimbang anaknya. Hal ini dapat dilakukan dengan memberikan bimbingan atau edukasi untuk mengubah integritas yang dapat memusatkan dalam meningkatkan gizi ibu dan anak. Hasil penelitian yang dilakukan di Desa Kuala Indah Kecamatan Sei Suka, Kabupaten Batu Bara diraih data bahwa pengetahuan ibu mengenai pemenuhan gizi seimbang untuk balita berada dalam nilai 11,2% dengan kelas 10. Ibu yang memiliki integritas (+) bernilai 80,9% sebanyak 72 orang dan untuk integritas (-) bernilai 19,1% sebanyak 17 orang. Integritas ibu dalam pencegahan stunting pada balita yang mempunyai nilai cukup dengan sikap (-) bernilai 70,5% sedangkan dalam responden rendah berdasarkan grafik bernilai 29,4% sebanyak 5 orang ibu
Performing Discursive Inclusion in Platform-Native Journalism: A Critical Discourse Analysis of Religious Minority Representation on Indonesian YouTube News Media Gustiara, Gustiara; Nurbaya, Siti
Journal of Religious Studies Vol. 1 No. 2 (2025): Journal of Religious Studies
Publisher : 3 Issues per year (April, August and December)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64780/jors.v1i2.148

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This study examines how religious minorities are represented and made intelligible within platform-native journalism, with particular attention to the discursive strategies employed by Indonesian digital news media on YouTube. The purpose of the study is to critically explore how intercultural meanings, inclusivity, and social legitimacy are constructed through audiovisual news content featuring minority religious groups, and how such representations operate within broader social and ideological contexts. Using a qualitative research design, the study applies Critical Discourse Analysis based on Teun A. van Dijk’s three-dimensional framework, encompassing textual structures, social cognition, and social context. The primary data consist of selected special-feature videos produced by Kumparan’s YouTube channel that focus on Sikh and Orthodox Christian communities in Indonesia, supported by secondary data from relevant literature and institutional documents. The findings reveal that platform-native journalism does not merely report on religious diversity but actively performs discursive inclusion through careful lexical choices, narrative framing, visual composition, and dialogic presentation. These strategies position minority religions as legitimate social actors while simultaneously aligning journalistic narratives with dominant norms of tolerance, harmony, and national pluralism. At the level of social cognition, the media organization demonstrates an awareness of its influential role in shaping public understanding of religious difference, while at the level of social context, the discourse reflects broader efforts to manage religious diversity within a multicultural society. The significance of this study lies in its contribution to religious and media studies by highlighting how digital journalism platforms function as sites where inclusion is not only articulated but enacted discursively. By foregrounding platform-native news practices, this research offers a nuanced understanding of religion, media power, and intercultural communication in contemporary society, making it relevant to international discussions on religion in the digital public sphere.
Problem Based Learning Strategy Models at Islamic Universities Nurbaya, Siti
Fusshilat : Jurnal Studi Pendidikan dan Keislaman Vol 1 No 2 (2025): June
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) STIT Sunan Giri Bima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47625/fusshilat.v1i2.1142

Abstract

This paper aims to analyze Problem-Based Learning (PBL) learning strategy models in Islamic universities. This study uses a qualitative method with a literature study approach, then analyzed starting from data reduction, data presentation, and drawing conclusions. To ensure valid data, this study uses source triangulation to find different gaps while obtaining accurate and consistent data. The findings indicate that the PBL learning model in Islamic universities is rooted in two main frameworks: the Problem-Based Learning model by Bransford and Stein and the Problem-Solving Learning model of the troubleshooting type proposed by David H. Jonassen. In its implementation, both models develop adaptively through self-directed learning, collaborative, and scaffolding approaches. Furthermore, this study provides a new contribution by showing that the implementation of PBL in Islamic universities is not only oriented towards cognitive aspects, but also integrates religious and ethical values ​​in the learning process. These findings confirm that PBL is a flexible, contextual learning model, and has great potential in developing critical and reflective thinking skills, while also shaping students' character holistically.
IMPLEMENTASI  MODEL PEMBELAJARAN INOVATIF UNTUK MENINGKATKAN KETERLIBATAN SISWA DALAM PELAJARAN SEJARAH Nurbaya, Siti; Azizah Harahap, Mahlaini; Hasrul Haris, Mgs; Syarifuddin, Syarifuddin; Oktapiani, Rani
ADIDAYA : Aplikasi Pendidikan dan Sosial Budaya Vol 3 No 1 (2026)
Publisher : Pengelola Jurnal Politeknik Negeri Ketapang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58466/hd9yb647

Abstract

In the era of Society 5.0, history education faces a major challenge in the form of the stigma that it is a boring subject that focuses too much on memorization. This has an impact on low student engagement, both behaviorally, emotionally, and cognitively. In fact, 21st-century education requires a paradigm shift from teacher-centered learning to student-centered learning in order to develop critical thinking skills and historical awareness. Using library research methods through a qualitative approach, this study synthesizes four main models: Project-Based Learning, Problem-Based Learning, Gamification, and Inquiry-Based Learning. The results of the analysis show that PjBL is effective in building authentic experiences through concrete products, PBL hones analytical skills on historical issues, Gamification increases extrinsic motivation through game elements, and Inquiry encourages research independence. Although these models are significantly capable of activating students' behavioral, emotional, and cognitive participation, their implementation still faces challenges in the form of digital infrastructure gaps and limited teacher competencies. This study concludes that the adaptive combination of various innovative models is the key to transforming static historical narratives into relevant and collaborative learning processes for the 21st century generation
Prediction of Antidiabetic Activity of Swietenia mahagoni Compounds through PPARγ Activation: Machine Learning and Molecular Docking Analysis Veranita, Weri; Nurbaya, Siti
Indonesian Journal of Medical Chemistry and Bioinformatics Vol. 4, No. 2
Publisher : UI Scholars Hub

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Abstract

Type 2 diabetes mellitus is a chronic metabolic disorder requiring long-term therapy, yet current synthetic PPARγ agonists like thiazolidinediones are often associated with serious adverse effects. Therefore, identifying natural alternatives from sources such as Swietenia mahagoni is essential to provide effective therapy with potentially lower toxicity profiles. This study employed an in silico machine learning approach using SkelSpheres descriptors to predict the IC₅₀ values of compounds derived from the seeds of Swietenia mahagoni against PPARγ, followed by molecular docking validation using Molegro Virtual Docker (MVD). The predictive model for PPARγ agonists demonstrated acceptable validity (R²-test = 0.5308; accuracy = 84.01%). Four compounds from S. mahagoni showed predicted IC₅₀ values below 1 µM (0.0973–0.9527 µM), categorized as “Predicted Excellent activity.” Docking simulations revealed that the bibenzyl derivative 2-Carboxy-3,5-Dihydroxy-4-Geranylbibenzyl (CID: 25135579) and β,β-Carotene tetrol (CID: 23258402) exhibited binding affinities comparable to the control ligand thiazolidinedione, with Rerank Scores of-114.991 and -109.764 kJ/mol, respectively. In conclusion, the bibenzyl derivative and carotene tetrol from S. mahagoni represent promising natural candidates for PPARγ agonists, providing a strong rationale for further in vitro and in vivo investigations as potential antidiabetic agents.
Perancangan Label Kemasan Produk Olahan Gerit Duwet Polinema Tortilla Chips sebagai Media Promosi Lestari, Baroroh; Utamaningsih, Arni; Nurbaya, Siti; Anjari, Becik Gati; Himma, Mahmudatul
Jurnal Kewirausahaan dan Bisnis Vol 28, No 1 (2023): June
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkb.v28i1.67153

Abstract

Masyarakat Dusun Petungsewu, Desa Duwet, Kecamatan Tumpang, Kabupaten Malang merupakan penghasil olahan gerit berupa Duwet Polinema Tortilla Chips (Dupitos). Dupitos merupakan tortilla chips dengan bahan baku dasar jagung. Terdapat kelemahan dalam usaha tersebut, yakni mengemas hasil ke dalam label sederhana, membuat produk secara visual kurang berkesan bagi konsumen. Oleh karena itu, tujuan kegiatan adalah merancang label kemasan Dupitos sebagai media promosi. Kegiatan dilaksanakan mulai bulan April sampai November 2022. Metode dalam kegiatan ini menggunakan pengumpulan data dan analisis. Proses desain menggunakan teknik THINK. Kegiatan ini menghasilkan label untuk Dupitos. Desain label mengadopsi metode THINK untuk mendesain label setelah melakukan analisis SWOT. Kegiatan yang telah dilaksanakan di masyarakat Dusun Duwet Desa Petungsewu Kabupaten Tumpang mampu meningkatkan penjualan Dupitos. Hal ini dapat dilihat dari penjualan yang semula hanya 20 pak ukuran 100g per minggu menjadi 35 pak ukuran 100g dan 10 pak ukuran 250g per minggu.Kata kunci: desain; Dupitos; label; Petungsewu
Co-Authors . Zulfan Adiansyah Adiansyah, Adiansyah Ahmad Gazali, Ahmad Albert Rufinus Allevia Yumnanisha, Defin Anisa Anisa Anjari, Becik Gati Arni Utamaningsih Aryo Tedjo Asnuddin, Asnuddin asyir, alfiah Asyir, Alfiah Khoiri Azhar Alam Azizah Harahap, Mahlaini Baharuddin Hamzah Bambang Suryanto Baroroh Lestari Br Brahmana, Nettietalia Chandra, Devina Chotimah, Octavia Christianta, David Dalimunthe, Agusmal De Lux Putra, Effendy Derlina . Dicky Yuswardi Wiratma Eriwaty Silalahi, Yosy Cinthya Ernawati Sinaga fahima, sinaida Faruqi, Muhammad Fitrah, Harisa Fitri, Raissa Fitriani Fitriani Ginting, Pitalokasari br Gustiara, Gustiara Hasniati, Hasniati Hasrul Haris, Mgs Hermawansyah Hermawansyah Hermiza Mardesci Heru Utomo, Heru Himma, Mahmudatul Hutauruk, Dumartina Irianti Handayani, Supri Kholis Ridho, Kholis La Ode Sumarlin Laksono Trisnantoro Leny Dwi Astuti Lestari, Wita Lumbantoruan, Lamtiur Manase, Pebrianti Manurung, Kesaktian Marpaung, Jon Kenedy Mei Purwantini Meyliana Wulandari Monica Suryani Muhammad Irfan MUHAMMAD TAUFIK Nasaruddin Nurfadillah, Ainaya Nurhalisa, Nurhalisa Nuriyanti Sirait Nurussakinah, Nurussakinah Pangaribuan, Novalina Perri, Perri Pratiwi, Aulia Febriyanti Priltuis, Natanael Puji Sari Purba, Trionaldo Purwandari, Vivi Rahmah, Fiska Rani Oktapiani Rejekinta Munthe, Alfian rubino, rubino Ruslan Safwan, Ahmad Gazali Salsabila Shofia Rahma Samran, Samran Sapitri, Alfi Sembiring, Rinawati Setyawan Pujiono Sianipar, Artha Yuliana SIHOMBING, IWEL SUDARNO Silitonga, Maringan Simanjuntak, Kristina Simarmata, Yettrie Simatupang, Aprili Yanti Sitanggang, Berton Sitanggang, Eva Priasanti Sitanggang, Pontisari Siti Faridah Siti Maimunah Siti Nuryanti Sitompul, Desi Sitorus, Elly Sitorus, Elly Nurita Sitorus, Panal Situmorang, Winton F. Siva Fauziah, Siva Sofwan, Ahmad Gazali Sofyan . Suharyanisa Sukayasa Sumardi . Supartiningsih - - Supendi, Egih Suprianto Suprianto SURBAKTI, CHRISTICA ILSANNA Syahriani Syahriani, Syahriani SYAIFUL BAHRI Syarifuddin Syed Azhar Syed Sulaiman, Syed Azhar Syed Tang, Muhammad Tarigan, Yenni Gustian Thaib, Cut Masyithah urai salam Veranita, Weri Vivitri Dewi Prasasty Yamin, Ashabul Yanti Musyawarah Yosy Cinthya Eriwaty Silalahi Yusra, Yusra Zainuddin, Zainuddin Zuhairiah Nasution, Zuhairiah