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Penetapan Kadar Kafein Pada Minuman Berenergi Dalam Kemasan Sachet Yang Beredar Di Pasaran Nurbaya, Siti; Supartiningsih, Supartiningsih; Hutauruk, Dumartina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Pada proses pembuatan minuman berenergi sering ditambahkan zat – zat stimulan ke dalamnya, salah satunya adalah kafein. Efek kafein dapat menghilangkan rasa kantuk, dapat memberikan kebugaran dan kesegaran pada tubuh. Kafein dapat meningkatkan tekanan darah dan peningkatan pengeluaran urin. Tujuan penelitian ini adalah untuk mengetahui kandungan kafein dalam minuman berenergi kemasan sachet yang beredar di pasaran. Penetapan kadar kafein dilakukan secara kuantitatif dengan menggunakan metode iodometri. Hasil penelitian menunjukkan bahwa seluruh sampel menggunakan kafein sebagai zat stimulannya, dimana kadar kafein dengan kode A yaitu 48,80 mg, kadar kafein dengan kode B yaitu 46,44 mg, kadar kafein dengan kode sampel C yaitu 34,73 mg dan kadar kafein dengan kode D yaitu 30,71 mg. Kesimpulan dari penelitian ini adalah bahwa semua sampel masih memenuhi peryaratan menurut Standart Nasional Indonesia (SNI) No. 01. 6684. 2002 dengan batas kadar kafein dalam minuman adalah tidak lebih dari 50 mg.
FORMULASI KRIM ANTI-AGING DARI EKSTRAK EKSTRAK ETANOL KACANG HIJAU (Phaseolus radiatus Roxb. Non-L.) Nurbaya, Siti; Br Brahmana, Nettietalia; Rejekinta Munthe, Alfian; Pangaribuan, Novalina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Background: green beans are one type of peanut that are widely consumed by communities as functional. The green nut contains a secondary metabolic compound, among them flavonoid, saponin, steroid/triterpenoid, and tannin, which are potent antioxidants.Research goals: for this study, there is an introduction to the new anti-aging activity in green beans ethanol (Phaseolus radiatus Roxb. non-L..). Research methods: this research method USES experimental methods with 5% concentration, 10%, and 15%. Then compared to the availability in the market and blanks. Some tests have been made against availability, including physical qualities of ready cream including homosexual, existing stability observations, pH, viscosity tests of volunteers, and anti-aging activities of volunteers. Results: the results from the study are the result of a stable cream test at room temperature for four weeks. Organoleptic results in Blanko’s formula and control formulas have not undergone any discoloration, changes in smell and phase separation after four-week long storage of ph cream meet good requirements in skin ph, no side effects of irritation and availability of green bean extract cream (Phaseolus radiatus Roxb. Non-L.) can demonstrate anti-aging effectiveness at 15% concentration. Conclusion: research suggests that supple green bean extract cream has an anti-aging activity.
Pengaruh Konseling Terhadap Kepatuhan Pasientuberculosis Di Puskesmas Langsa Lama Kota Langsa Nurbaya, Siti; Nuriyanti Sirait; Yanti Musyawarah
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 6 No. 1 (2024): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

The consequences of non-compliance with long-term treatment are deteriorating health and increasing treatment costs. Non-adherence of TB sufferers to treatment causes low cure rates, high mortality rates and increased recurrence and what is more fatal is the occurrence of germ resistance to several anti-tuberculosis drugs, so TB disease is very difficult to cure. The purpose of this study was to determine the effect of counseling on medication adherence. This type of research is a correlation analytic research with cross sectional method. The population in this study were TB sufferers with a sample of 35 people. The data were obtained using a questionnaire and the data were analyzed using the Chi-Square statistical test. The results showed that 1) the level of patient compliance in taking drugs in patients with tuberculosis at the Langsa Lama Health Center was in the majority with high adherence 2) the majority of counseling was given to patients with tuberculosis at the Langsa Lama Health Center in the good category, 3) there was an influence of counseling on patient compliance.
In Silico Analysis of Tea Leaf Compounds Targeting Inflammatory Pathways and Acne-Related Genes Sumarlin, La Ode; Nurbaya, Siti; Wulandari, Meyliana; Sulaiman, Syed Azhar Syed
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 2, November 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i2.46468

Abstract

Acne (Acne vulgaris) is a chronic skin disease affected by Cutibacterium acnes infection and inflammatory pathways that trigger innate immune responses, such as inflammasome activation. The expression of inflammation-related genes plays a critical role in acne pathogenesis and immune modulation. This study aims to identify compounds from tea leaves (Camellia sinensis var. assamica) that can treat acne by influencing the expression of inflammatory-related genes through in silico analysis. The GSE6475 dataset was utilized to identify differentially expressed genes (DEGs) between acne-affected and normal skin samples (each group n=6). A total of 573 DEGs were identified and mapped to the KEGG inflammatory pathway. The hub gene analysis results showed six genes, including CXCL1, STAT1, and PIK3 (adj. P-value < 0.05). These key genes were then used to cross-validate skin grouping with acne lesions and normal skin. The structure of compounds (natural products) in tea leaves (C. sinensis var. assamica) was obtained from the PubChem database, and their activity against target proteins associated with the identified key genes was predicted using the SkelSpheres descriptor and Support Vector Regression method. This quantitative structure–activity relationship (QSAR)-based machine learning approach was selected because it enables high-throughput prediction of inhibitory potential using chemical descriptors and experimentally derived bioactivity data, providing broader predictive power than conventional molecular docking or molecular dynamics, which rely mainly on structural and energetic estimations. The in-silico prediction results showed that compounds such as theobromine, assamsaponin, procyanidin, and caffeine have exhibited good predicted activity (IC₅₀ ranging from 1.125 to 1.320 μM) as potential inhibitors of the PI3K/Akt pathway, which is known to play a role in the pathogenesis of acne. 
PENGETAHUAN ORANG TUA TERHADAP PEMENUHAN GIZI SEIMBANG DALAM PENCEGAHAN STUNTING PADA BALITA DI DESA KUALA INDAH KECAMATAN SEI SUKA KABUPATEN BATU BARA Rubino, Rubino; Nurfadillah, Ainaya; Chotimah, Octavia; Nurbaya, Siti; Faridah, Siti; Fitrah, Harisa
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 9 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i9.3342-3348

Abstract

Stunting ialah keadaan gagal tumbuh yang diakibatkan rendahnya gizi pada 1000 HPK anak, yakni mulai dari dalam kandungan sampai usia 2 tahun. Problem tersebut berupa pemberian asupan gizi yang minim untuk tenggang waktu relatif lama dan mengkonsumsi makanan yang tidak selaras dengan keperluan gizi. Seorang anak dikatakan menderita stunting jika tinggi badan berada dibawah anak seumurannya. Penyebab terjadinya stunting tidak sekedar kemiskinan serta kebutuhan pangan, akan tetapi dalam bentuk pemeliharaan dan pengasuhan pada anak. Pokok utama penyebab stunting ialah rendahnya gizi ketika ibu hamil. Pencegahan stunting amat perlu dilakukan agar tidak terjadinya pertumbuhan dan perkembangan yang buruk. Salah satu cara yang dapat dilakukan untuk meminimalisir peningkatan stunting ialah pengetahuan orang tua terhadap pemenuhan gizi seimbang anaknya. Hal ini dapat dilakukan dengan memberikan bimbingan atau edukasi untuk mengubah integritas yang dapat memusatkan dalam meningkatkan gizi ibu dan anak. Hasil penelitian yang dilakukan di Desa Kuala Indah Kecamatan Sei Suka, Kabupaten Batu Bara diraih data bahwa pengetahuan ibu mengenai pemenuhan gizi seimbang untuk balita berada dalam nilai 11,2% dengan kelas 10. Ibu yang memiliki integritas (+) bernilai 80,9% sebanyak 72 orang dan untuk integritas (-) bernilai 19,1% sebanyak 17 orang. Integritas ibu dalam pencegahan stunting pada balita yang mempunyai nilai cukup dengan sikap (-) bernilai 70,5% sedangkan dalam responden rendah berdasarkan grafik bernilai 29,4% sebanyak 5 orang ibu
Prediction of Antidiabetic Activity of Swietenia mahagoni Compounds through PPARγ Activation: Machine Learning and Molecular Docking Analysis Veranita, Weri; Nurbaya, Siti
Indonesian Journal of Medical Chemistry and Bioinformatics Vol. 4, No. 2
Publisher : UI Scholars Hub

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Abstract

Type 2 diabetes mellitus is a chronic metabolic disorder requiring long-term therapy, yet current synthetic PPARγ agonists like thiazolidinediones are often associated with serious adverse effects. Therefore, identifying natural alternatives from sources such as Swietenia mahagoni is essential to provide effective therapy with potentially lower toxicity profiles. This study employed an in silico machine learning approach using SkelSpheres descriptors to predict the IC₅₀ values of compounds derived from the seeds of Swietenia mahagoni against PPARγ, followed by molecular docking validation using Molegro Virtual Docker (MVD). The predictive model for PPARγ agonists demonstrated acceptable validity (R²-test = 0.5308; accuracy = 84.01%). Four compounds from S. mahagoni showed predicted IC₅₀ values below 1 µM (0.0973–0.9527 µM), categorized as “Predicted Excellent activity.” Docking simulations revealed that the bibenzyl derivative 2-Carboxy-3,5-Dihydroxy-4-Geranylbibenzyl (CID: 25135579) and β,β-Carotene tetrol (CID: 23258402) exhibited binding affinities comparable to the control ligand thiazolidinedione, with Rerank Scores of-114.991 and -109.764 kJ/mol, respectively. In conclusion, the bibenzyl derivative and carotene tetrol from S. mahagoni represent promising natural candidates for PPARγ agonists, providing a strong rationale for further in vitro and in vivo investigations as potential antidiabetic agents.
Perancangan Label Kemasan Produk Olahan Gerit Duwet Polinema Tortilla Chips sebagai Media Promosi Lestari, Baroroh; Utamaningsih, Arni; Nurbaya, Siti; Anjari, Becik Gati; Himma, Mahmudatul
Jurnal Kewirausahaan dan Bisnis Vol 28, No 1 (2023): June
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkb.v28i1.67153

Abstract

Masyarakat Dusun Petungsewu, Desa Duwet, Kecamatan Tumpang, Kabupaten Malang merupakan penghasil olahan gerit berupa Duwet Polinema Tortilla Chips (Dupitos). Dupitos merupakan tortilla chips dengan bahan baku dasar jagung. Terdapat kelemahan dalam usaha tersebut, yakni mengemas hasil ke dalam label sederhana, membuat produk secara visual kurang berkesan bagi konsumen. Oleh karena itu, tujuan kegiatan adalah merancang label kemasan Dupitos sebagai media promosi. Kegiatan dilaksanakan mulai bulan April sampai November 2022. Metode dalam kegiatan ini menggunakan pengumpulan data dan analisis. Proses desain menggunakan teknik THINK. Kegiatan ini menghasilkan label untuk Dupitos. Desain label mengadopsi metode THINK untuk mendesain label setelah melakukan analisis SWOT. Kegiatan yang telah dilaksanakan di masyarakat Dusun Duwet Desa Petungsewu Kabupaten Tumpang mampu meningkatkan penjualan Dupitos. Hal ini dapat dilihat dari penjualan yang semula hanya 20 pak ukuran 100g per minggu menjadi 35 pak ukuran 100g dan 10 pak ukuran 250g per minggu.Kata kunci: desain; Dupitos; label; Petungsewu
Implementasi Model Pembelajaran TGT (Teams Games Tournament) Berbantuan Kartu Kata & Kalimat untuk Meningkatkan Nilai Karakter dan Hasil Belajar Siswa pada Materi Sejarah Pancasila Kelas IV SD Negeri Tanjungrejo 3 Kota Malang Trisnadiansyah, Vikri; Agus Setiawan, Dwi; Nurbaya, Siti
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 03 (2026): Volume 11 Nomor 03, September 2026 Published
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i03.62350

Abstract

This research aims to describe the improvement of student character values and learning outcomes through the implementation of the TGT (Teams Games Tournament) cooperative learning model assisted by Word & Sentence Cards on the History of Pancasila material for Grade IV students at SD Negeri Tanjungrejo 3 Malang City. This research employs a Classroom Action Research (CAR) design based on the Kemmis & McTaggart model, carried out in two cycles with each cycle consisting of four stages: planning, acting, observing, and reflecting. The research subjects were 28 Grade IV students at SD Negeri Tanjungrejo 3 Malang City in the 2025/2026 academic year. Data were collected through written tests (pretest and posttest), character value observation sheets, student activity observation sheets, and student response questionnaires. The research results demonstrate significant improvement across all measured aspects. Student learning outcomes increased from an average of 60.4 (pretest) to 73.6 in Cycle I and 84.5 in Cycle II, with the percentage of completeness rising from 0% to 57% in Cycle I and reaching 100% in Cycle II, surpassing the established success indicator of 80%. The average character value also improved from 68.8 in Cycle I to 81.3 in Cycle II, with 93% of students achieving the Good or Very Good category. Student learning activity increased from an average of 62.5 in Cycle I to 78.1 in Cycle II. It is concluded that the TGT learning model assisted by Word & Sentence Cards is effective in simultaneously improving character values and learning outcomes of Grade IV students on History of Pancasila material.
Co-Authors . Zulfan Adiansyah Adiansyah, Adiansyah Agus Setiawan, Dwi Ahmad Gazali, Ahmad Albert Rufinus Allevia Yumnanisha, Defin Anisa Anisa Anjari, Becik Gati Arni Utamaningsih Aryo Tedjo Asnuddin, Asnuddin asyir, alfiah Asyir, Alfiah Khoiri Azhar Alam Baharuddin Hamzah Bambang Suryanto Baroroh Lestari Br Brahmana, Nettietalia Chandra, Devina Chotimah, Octavia Christianta, David Dalimunthe, Agusmal De Lux Putra, Effendy Derlina . Dicky Yuswardi Wiratma Eriwaty Silalahi, Yosy Cinthya Ernawati Sinaga fahima, sinaida Faruqi, Muhammad Fitrah, Harisa Fitri, Raissa Fitriani Fitriani Ginting, Pitalokasari br Hasniati, Hasniati Hermawansyah Hermawansyah Hermiza Mardesci Heru Utomo, Heru Himma, Mahmudatul Hutauruk, Dumartina Irianti Handayani, Supri Kholis Ridho, Kholis La Ode Sumarlin Laksono Trisnantoro Leny Dwi Astuti Lestari, Wita Lumbantoruan, Lamtiur Manase, Pebrianti Manurung, Kesaktian Marpaung, Jon Kenedy Mei Purwantini Meyliana Wulandari Monica Suryani Muhammad Irfan Muhammad Tang MUHAMMAD TAUFIK Nasaruddin Nurfadillah, Ainaya Nurhalisa, Nurhalisa Nuriyanti Sirait Nurussakinah, Nurussakinah Pangaribuan, Novalina Perri, Perri Pratiwi, Aulia Febriyanti Priltuis, Natanael Puji Sari Purba, Trionaldo Purwandari, Vivi Rahmah, Fiska Rejekinta Munthe, Alfian rubino, rubino Ruslan Safwan, Ahmad Gazali Salsabila Shofia Rahma Samran, Samran Sapitri, Alfi Sembiring, Rinawati Setyawan Pujiono Sianipar, Artha Yuliana SIHOMBING, IWEL SUDARNO Silitonga, Maringan Simanjuntak, Kristina Simarmata, Yettrie Simatupang, Aprili Yanti Sitanggang, Berton Sitanggang, Eva Priasanti Sitanggang, Pontisari Siti Faridah Siti Maimunah Siti Nuryanti Sitompul, Desi Sitorus, Elly Sitorus, Elly Nurita Sitorus, Panal Situmorang, Winton F. Siva Fauziah, Siva Sofwan, Ahmad Gazali Sofyan . Suharyanisa Sukayasa Sumardi . Supartiningsih - - Supendi, Egih Suprianto Suprianto SURBAKTI, CHRISTICA ILSANNA Syahriani Syahriani, Syahriani SYAIFUL BAHRI Syed Azhar Syed Sulaiman, Syed Azhar Syed Tarigan, Yenni Gustian Thaib, Cut Masyithah Trisnadiansyah, Vikri urai salam Veranita, Weri Vivitri Dewi Prasasty Yamin, Ashabul Yanti Musyawarah Yosy Cinthya Eriwaty Silalahi Yusra, Yusra Zainuddin, Zainuddin Zuhairiah Nasution, Zuhairiah