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Dian Puspita
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Aktivitas Antibakteri Ekstrak Biji Anggur (Vitis vinifera L.) terhadap Enterococcus faecalis Vera Nanda, Elsa; Hamida, Fathin; Puspita, Dian; Syafriana, Vilya
BIOEDUSCIENCE Vol 8 No 3 (2024): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/14278

Abstract

Background: Grape seeds are one part of the grape plant known to have antibacterial properties because they contain secondary metabolite compounds such as tannins and flavonoids. Previous studies have shown that grape seed extract has antibacterial activity against Streptococcus pyogenes, Streptococcus mutans, Propionibacterium acnes, and Staphylococcus epidermidis. However, testing for Enterococcus faecalis from 70% ethanol extract and n-hexane has not been found. This study aims to determine the antibacterial activity of n-hexane and 70% ethanol extract from grape seeds against E. faecalis bacteria. Methods: Extraction was carried out using the maceration method using two solvents: n-hexane and 70% ethanol. The antibacterial activity test used the disc diffusion method to determine the Diameter Inhibitory Power (DDH) value at extract concentrations of 5%, 10%, 20%, and 40%. Results: The results obtained showed that grape seed extract had antibacterial activity against E. faecalis, with the DDH value of n-hexane extract respectively being 9.70 mm, 10.36mm, 10.55mm, and 11.31 mm at concentrations of 5%, 10%, 20%, and 40%. The DDH value of the 70% ethanol extract was 11.20 mm, 12.34mm, 13.63mm, and 15.49 mm at concentrations of 5%, 10%, 20%, and 40%, respectively. Conclusions: These results indicate that n-hexane and 70% ethanol extract from grape seeds have antibacterial potential against E. faecalis.
Co-Authors Abdullah, Dessy Adelin, Prima Adi Prasetia Nanda Afriyanti Agung purnomo Ahmad Fauzan Fathoni Ahmad, Syukron Aini, Afifah Nuril Alexsander, Gilbert Ali, Muhammad Chaidar Alifia, Syafira Amelda Indra Triana Andoyo, Andreas Andreas Andoyo Andriyani Ermica Sari Anggi Trio Meisya Anggraini, Sri Hastini Arica Pavitasari Astuti, Sariyah Astuti, Sariyah Astuti, Sariyah Budi Usmanto Citra Dewi Debie Anggraini Dewi Fadilasari Dewi, Ayu Ramadhani Kumala Donny Citra Lesmana Eka Yuliana Eko Hendrawan Erlin -, Erlin Erliza Septia Nagara Ermawati, Liya Fajar Pangestu, Fajar Fathin Hamida Fidiariani Sjaaf H.B, Bambang E Haiga, Yuri Hamama Pitra, Dian Ayu Hanif Hanif Haryani , Fitria Helmizar, Roland Heru Purnomo I Gusti Putu Purnaba Indriana Mukti Indriyani Islam Mahdi Islam Mahdi, Muhammad Jupon, Rara Marselina Kris Tri Basuki Kristina, Marilin Kurnia Wulandari Laura Zeffira Leni Anggraeni Leni Anggraeni liana, nana Linda, Vitoria Lubis, Elektina M. Syaikhan Azzamul Khair Mahatma, Gangga Marselina Jupon, Rara Mar’atus Sholihah Meiliani, Mutia Melya Susanti Mhd Nurhuda Mislinawati Mislinawati Mislinawati, Mislinawati Miswan Gumanti Muhamad Muslihudin Nabila Nur Anisah Nahzia Septia Fondri Nani Jelmila, Sri Nilas Warlem Ningrum, Ajeng Amelia Novi Ayu Kristina Dewi Novita Andriyani Nurazizah, Hizba Nurhuda, Mhd Nurimaniwathy, Nurimaniwathy Nurlela Nurlela Nurlela Nurul Utami Paisah Permatasari, Berlintina Pramudi, Agung Pramudi, Agung Prasetia Nanda, Adi Prasetyo, Langgeng Prasetyo Pratama, Abdullah Reza Priyono Priyono Priyono Puspita PA, Tri Puspita PA Putra, Aditya Erlangga Putri, Nia rahmawati, selvi Rahsel , Yoeyong Rahsel, Yoeyong Rahsel, Yoeyong Rara Marselina Jupon Rika Amran Rina Wati Riski Istiani Rizal Aditya Rifaii Romi Ramkita Rudiyanto, Waluyo Ruhsyahadati Salsabila Az-Zahra Sandria Santia Wulan Sari Saputro, Isnu Aji Sari, Elsa Puspita Sariyah Astuti Septia Nagara, Erliza Sherly, Ulfa Siana, Yusti Siti Mukodimah Siti Rahmi, Nur Haji Sjaaf, Fidiariani Sofiyati, noor Sri Hartati Sri Nani Jelmila Sudewi Sudewi Sugiman . Sulistiana, Devita Suprayogi Suprayogi Syafriana, Vilya Tarigan, Milda Aprilina Taufik Taufik Taufik Tri Septiana, Vina Tri Susilowati Tri Yana, Rahma Tri Yuni Hendrowati Tri Yuni Hendrowati Trijayanti, Ery Trisnawati Trisnawati Triyana, Rahma V. Nanda, Elsa Valencia Nanda Luckyta Vani, Ade Teti Vera Nanda, Elsa Vitoria Linda Vritta Amroini Wahyudi Wasbiru, Annita Winia Waziana Wulandari , Wulandari Wulandari Wulandari Yuliza Birman Yuni Handayani Yuri Fitrian Yusti Siana Zain, Muhammad Fathurrahman Zulkarnaini, Aryaldy