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All Journal Hemera Zoa Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan World Nutrition Journal Respiratory Science The Indonesian Journal of Community and Occupational Medicine The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia

Ari Fahrial Syam

Division Of Gastroenterology, Department Of Internal Medicine, University Of Indonesia/Cipto Mangunkusumo Hospital, Jakarta

Author-ID : 399120

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Public Health

Published : 115 Documents Claim Missing Document

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PCS-5 Nitric Oxide Induced Basal Cell Hyperplasia and Lamina Propria Elongation in Rat Gastroesophageal Junction Tena Djuartina; Bambang Pontjo Priosoeryanto; Ari Fahrial Syam; Ahmad Aulia; Tri Isyani Tungga Dewi
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (582.843 KB)

NO (Nitric Oxide) is an inorganic compound composed of nitrogen and oxygen, NO is also produced in various places on various types of mammalian cells. NO as a radical compound is important in mediating physiological and pathological events in mammals including humans [1].GEJ (gastroesophageal junction) is a transition zone between the surface of esophagus which is covered by stratified squamous epithelium to the gastric mucosa which consists of simple columnar epithelium (z-line), where circular muscle of esophagus fuse with oblique muscle and lipid layer of the gaster. At the lower part of GEJ, there is the lower esophageal sphincter (LES) that not only allow food to move into stomach and works as an exit passage of the gas, but also inhibit reflux of any substances that potentially can cause harm to the esophagus [2].Petersson et al, found that chronic exposure to cytotoxic levels of NO can cause inflammation, intestinal metaplasia and neoplasia. Although it is known that gastric acid, pepsin and bile acids can cause adenocarcinoma of distal esophagus and GEJ, NO exposure and nitrosative stress role in this phenomenon is yet to be fully understood and further study is needed [3].The purpose of this was to identify and compare the histopathological changes occurring in GEJ in relation to administration of physiological concentration of nitrate dissolved in HCl and ascorbic acid. As such, the animal model used in this study can be used to study and represent the changes microscopically, because obtaining a full thickness biopsy from a human subject can be difficult to perform.

COVID-19 treatment during and after recovery: What to expect Ari Fahrial Syam
World Nutrition Journal Vol. 4 No. S3 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S3.0011

Currently, there are no clinically specific drug for COVID-19, neither novel treatments nor vaccines. Hospitals and researchers over the world are testing many different therapies on coronavirus-positive patients in an effort to find a potential COVID-19 treatment, a few medications that have been making a buzz in the science community such as remdesivir, hydroxychloroquine and chloroquine, favipiravir, oseltamifir, lopinavir/ritonavir, azithromycin, plasma convalescent, dexamethasone and stem cell.

Indonesian Health Workers during COVID-19 Pandemic Ari Fahrial Syam
The Indonesian Journal of Community and Occupational Medicine Vol. 1 No. 2 (2021): ijcom
Publisher : ILUNI MKK FKUI and PRODI MKK FKUI

Burnout in health workers causes physical and emotional fatigue; it is a condition of a long-term affective state and is an outcome of cumulative and chronic exposure to stress, particularly work stress. Burnout was especially evident in hospitals with limited availability of medical staff. Mental burdens are higher because they face more patients infected by the coronavirus, followed by the trauma of witnessing deaths among patients. These conditions may weaken the immune system, increasing vulnerability to COVID-19 and higher risk of severe symptoms that can cause death. When talking out of context of the pandemic, burnout can also be associated with various other diseases, including IBS.4 Burnout was associated with a 2.41-fold elevated prevalence of IBS after adjusting for potential confounding variables, including job strain.

Candidiasis in Malignancy Diany N Taher; Ari Fahrial Syam; Murdani Abdullah; Jumhana Atmakusuma; Khie Chen
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 1, April 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/71200628-31

Esophageal candidiasis presents with a range of clinical findings and is rarely found among immunocompetent patient without predisposing factors. Between 20-50% of patient may be asymptomatic. One of predisposing factor of candidiasis is immunocompromised condition due to malignancy. Dysphagia is the most frequently presented feature of esophageal carcinoma. We demonstrated a case of esophageal candidiasis as one of early clinical presentation in patient with esophageal carcinoma. Keywords: esophageal candidiasis, esophageal carcinoma

Management of Upper Gastrointestinal Bleeding due to NSAID Gastropathy that is Unresponsive to Ranitidine Lusy Erawati; Sayid Ridho; Ginova Nainggolan; Ari Fahrial Syam; Chudahman Manan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 4, ISSUE 2, August 2003
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/42200359-63

Non steroidal anti-inflammatory drugs (NSAIDS) are now commonly used in clinical practice. On the other hands, this drug could result severe complication such as bleeding and perforation. In such condition, proton pump inhibitor can be used to stop bleeding than H2 antagonists. We reported one cases of upper gastrointestinal bleeding due to NSAID gastropathy that was unresponsive to Ranitidine. The treatment was suitable to proton pump inhibitor that could overcome upper gastrointestinal bleeding.

Multiple Lesion of the Colon and Ileocaecal Valve in Patient with Colitis Tuberculosis with Positive Bacilli Examination in the Stool Ali Imron Yusuf; Ari Fahrial Syam; Marcellus Simadibrata; Achmad Fauzi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, ISSUE 1, April 2009
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/101200933-37

It is sometimes hard to establish the diagnosis of colon tuberculosis because the ulceration features on ileocaecal valve and caecum are not specific. Moreover, biopsy of lesion area can only provide 60-80% detection. The lesions usually include linear or transversal ulcer, nodule, abnormal form of ileocaecal valve and caecum, inflammatory polyp and irregular multiple fibrous bands. We report a case of colon tuberculosis in a 32-years-old woman with giant ulcer and pseudopolyps at ileus terminalis and ileocaecal junction detected by colonoscopy, in addition to multiple ulcers along the colon, starting from rectum to ascending colon. By fecal examination, positive Acid Fast Test (AFT) result was found and by chest X-ray, tuberculosis features were also found. Keywords: tuberculosis colitis, multiple ulcers in colon, giant ulcer, pseudopolyp, fecal AFT, colonoscopy

Identification and Stenting of Malignant Obstructive Jaundice : Determining the Success Rates of ERCP Budi Tan Oto; Achmad Fauzi; Ari Fahrial Syam; Marcellus Simadibrata; Murdani Abdullah; Dadang Makmun; Chudahman Manan; Abdul Aziz Rani; Daldiyono Daldiyono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 1, April 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Malignant and benign lesions may cause obstructive jaundice. The treatment of these conditions includes biliary stenting drainage, percutaneous transhepatic biliary drainage (PTBD), or surgical procedures. In advanced malignant jaundice, stent placement often turns out to be difficult. The aim of this study was to determine the success rates of malignant obstructive jaundice detection utilising endoscopic retrograde cholangiopancreatography (ERCP) and its stent placement procedure. Method: We conducted a retrospective study in 139 patients who undergone ERCP in Cipto Mangunkusumo Hospital between October 2004 and July 2008. Data was analyzed descriptively with SPSS version 17.0. Results: Of 139 study subjects, 131 (94.2%) of them had clinical obstructive jaundice (direct bilirubin indirect bilirubin level). There were 73 (55.7) male patients, with age range of 20-84 years. Among 114 patients with identified cause of obstruction, 57 (50%) patients had undergone stent placement; however, only 32 (56.1%) patients had successful stent placement. Our descriptive analysis showed that age and sex did not affect the stent success rates, and malignancy was showed to be a factor of stent failure. Conclusion: ERCP appears to be reliable enough for identifying the cause of obstructive jaundice in most patients. In this study, the achieved success rate of stent placement is more than 50%. Moreover, such rate is lower in the malignant obstructive jaundice than the non-malignant counterparts. Papillary carcinoma is the most frequent cause of malignant obstructive jaundice. Keywords: ERCP, obstructive jaundice, stenting, malignancy

Gastroduodenal Mucosal Injury Profile in Long-Term Low-Dose Aspirin Users and Its Influencing Factors Franciscus Ari; Ari Fahrial Syam; Dadang Makmun; Suhendro Suhendro
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 17, No 3 (2016): VOLUME 17, NUMBER 3, December 2016
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Low-dose aspirin is the most common drug used for prevention of cardiovascular and cerebrovascular events. Long-term aspirin therapy can induce gastroduodenal mucosal injury, even in a very low dose (10 mg daily). The frequency of gastroduodenal injuries among long-term low-dose aspirin users in Indonesia is currently unknown. The aim of this study is to determine the prevalence of gastroduodenal mucosal injury, endoscopic findings, and influencing factors among long-term low-dose aspirin users in Cipto Mangunkusumo Hospital.Method: This study was a cross-sectional study conducted in Cipto Mangunkusumo Hospital, Jakarta. Subjects were patients aged ≥ 18 years old who had been using low-dose aspirin (75-325 mg) for at least the preceding 28 days. Ninety-five subjects were recruited consecutively in the period of December 2015 – April 2016. History taking, upper endoscopic examination, and histopathology examination for Helicobacter pylori infection were performed in all subjects. Endoscopic findings such as erosions and ulcers were assessed as mucosal injuries. Data were analysed to find prevalence, bivariate analysis (Chi-square test), and multivariate analysis (logistic regression test).Results: Mucosal injury was found in 49 subjects (51.6%; 95% CI: 41.6–61.7%), mucosal erosion in 38 subjects (40%; 95% CI: 30.2–49.9%) and ulcers in 11 subjects (11.6%; 95% CI: 5.2–18.0%). Only 44.9% patients with mucosal injury had dyspepsia symptoms. Double antiplatelet therapy increased the risk of mucosal injury (OR = 3.3; 95% CI: 1.3–8.5). However, proton pump inhibitor (PPI) decreased the risk of mucosal injury (OR = 0,2; 95% CI: 0,04 – 0,60).Conclusion: Gastroduodenal mucosal injury was found in more than half of long-term low-dose aspirin users. Double antiplatelet therapy increased the risk of mucosal injury, while PPI effectively reduced the risk.

Upper Gastrointestinal Abnormalities in Esophagogastroduodenoscopy Examination: Descriptive Study in PSUPAU Endoscopic Unit Julwan Pribadi; Sedijono Sedijono; Suryantini Suryantini; Marcellus Simadibrata; Ari Fahrial Syam; Murdani Abdullah; Achmad Fauzi; Dadang Makmun; Chudahman Manan; Daldiyono Daldiyono; Abdul Aziz Rani
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 9, ISSUE 3, December 2008
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/93200882-85

Background: The Endoscopy Unit of Indonesian Air Force Central Hospital Dr. Esnawan Antariksa, Jakarta, Indonesia, has just been established in late 2004 and it is still in developing process. This study was aim to depict the profile of patients who underwent esophagogastroduodenoscopy procedure in the unit. Method: This study was a retrospective study that analyzed data in endoscopic registry of patients who underwent esophagogastroduodenoscopy (EGD) examination from September 2004 to December 2007. Result: Total of 108 patients underwent EGD examination, comprised of 66 (61%) males and 42 (39%) females, with average age of 45.4 years old (range 16-77 years old). The most frequent indication for EGD was dyspepsia 63%, followed by hematemesis-melena 26% and dysphagia 5.5%. Among patients with dyspepsia, EGD revealed organic abnormalities in 71% patients, with descriptions of erosive gastritis 35%, gastritis 18%, bile reflux 7%, esophagitis 5% and gastric ulcer 3%. Among patients with hematemesis-melena, EGD revealed abnormalities, which were described as erosive gastritis 48%, esophageal varices bleeding 22%, gastric ulcer 18%, caustic injury 4%, and esophagitis 4%. Conclusions: EGD is an important procedure to ascertain the occurence of organic abnormalities in patient with gastrointestinal symptoms and signs e.g. dyspepsia and gastrointestinal bleeding. More than half of patients with dyspepsia showed organic abnormalities. Among patients with hematemesis-melena, erosive gastritis is more common than variceal bleeding. Keywords: esophagogastroduodenoscopy, dyspepsia, upper gastrointestinal bleeding, hematemesis melena

Serial Cases of Combining ESWL and ERCP Procedures in Management Chronic Pancreatitis and Difficult Bile Duct Stones Achmad Fauzi; Nur Rasyid; Ari Fahrial Syam; Murdani Abdullah; Dadang Makmun; Marcellus Simadibrata; Chudahman Manan; Abdul Aziz Rani; Daldiyono Daldiyono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, NUMBER 3, December 2009
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/1032009131-135

Extracorporeal shock wave lithotripsy (ESWL) has an established role in the management of pancreaticductalcalculiandasfurthertreatmentmodalityforlargeordifficultcomplicatedcommon bile duct(CBD)stones. Combinedwithminimally invasive endoscopic procedure suchasendoscopic retrogradecholangio-pancreatography(ERCP),it has replaced open surgeryas theinitial form of therapy. ESWL has also proved to bean effective therapyin treating intrahepaticstones that are refractory toroutine endoscopic extraction.Inthese serialcaseswe presentthree caseswhichusing combinedESWLandERCP procedurestotreatchronicpancreatitispainandgiantCBDstonethat presentinggoodresultsonfollowupwithoutanycomplication. Keywords:ESWL, ERCP,chronicpancreatitis, CBDstone

Co-Authors -, Arles - -, Suhendro - -, Suhendro - A.A. Ketut Agung Cahyawan W Aan Santi Aan Santi Abdul Aziz Rani Abdul Aziz Rani Abdul Aziz Rani Abdul Aziz Rani Achmad Fauzi ACHMAD FAUZI Achmad Fauzi Achmadsyah, Armand Adiwinata, Sheila Adjeg Tarius Afifah Is Agasjtya Wisjnu Wardhana Agnes Kurniawan Agustinus, Taolin Ahani, Ardhi Rahman Ahimsa, Titos Ahimsa, Titos Ahmad Aulia Ahmad Fauzi Ali Imron Yusuf Alkindi Bahar Amanda Pitarini Utari Andi Kristanto Andreas Pekey Andreas Pekey, Andreas Andree Kurniawan Andri Sanityoso Andri Sanityoso Andri Sanityoso Anggie Indari Anggilia Stephanie Anggilia Stephanie, Anggilia Anis Karuniawati Ari, Franciscus Arles - - Armen Muchtar Armen Muchtar Arya Govinda Aryanto Basuki Awang, Iqbal I Aziz Rani Bambang Pontjo Priosoeryanto Bambang Setyohadi Beatrice Belinda Phang Bhanu S Kumar Birry Karim Bona Adhista Bradley Jimmy Waleleng Bradley Jimmy Waleleng Budi Tan Oto C Martin Rumende C Rinaldi A Lesmana Caputra, Hadyanto Catarina Budyono Catarina Budyono, Catarina Ceva W. Pitoyo Christy Efiyanti Chudahman Manan Chudahman Manan Chudahman Manan Chyntia Olivia MJ Cindy Rahardja Cleopas Martin Rumende Dadang Makmun Daldiyono Daldiyono Daldiyono Daldiyono Daldiyono Hardjodisasto Daldiyono Hardjodisastro Daniel Gunawan Dante Saksono Harbuwono Deddy Gunawanjati Dedy Gunawanjati Sudrajat Dharmika Djojoningrat Diah Rini Handjari Diah Rini Handjari Diany N Taher Didi Kurniadhi Didi Kurniadhi Djulzasri Albar Dwi Suseno E Mudjaddid E Mudjaddid, E E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Eka Ginanjar Ekowati Rahajeng Ekowati Rahajeng Elizabeth Merry Wintery Ellen Susanti Elli Arsita Elli Arsita Elza Febria Sari Elza Febria Sari Endang Susalit Endang Susalit Ening Krisnuhoni Esthika Dewiasty, Esthika Euphemia Seto, Euphemia Evita H Effendi Evy Yunihastuti Fajar Raditya Fauzi Ahmad Muda Feriadi Suwarna FJW Ten Kate Florentina Caroline Puspita Franciscus Ari Futihati Ruhama Zulfa Gerie Amarendra Ginova Nainggolan Ginova Nainggolan GNJ Tytgat Grace Nami Sianturi Gunawanjati Sudrajat Hadyanto Caputra Hamzah Shatri Hamzah Shatri Hantoro, Ibnu Fajariyadi Haris Widita Haris Widita Haryanto Rahardjo Hasan Maulahela Hasan Maulahela Hasan Maulahela, Hasan Hayatun Nufus Hayatun Nufus Helsi Helsi Heru Sundaru Hery Djagat Purnomo Hery Djagat Purnomo Hotmen Sijabat I Gusti Bagus Wiksuana Ikhwan Rinaldi Ilham Ahmadi Ilum Anam Ilum Anam, Ilum Ina Susianti Timan Indra Marki Indra Marki Indra Marki Indra, Suwito Iqbal I Awang Ira Laurentika Irsan Hasan Ivo Novita Sah Bandar Iwan Ariawan Jacobus Albertus Jeffri Gunawan Joseph JY Sung Josephin Rasidi Julwan Pribadi Jumhana Atmakusuma Kaka Renaldi Karmel Tambunan Katharina Setyawati Khaira Utia Yusrie Kharia Utia Khie Chen L A Lesmana Laksmi, Purwita W. Laurentika, Ira Laurentius A Pramono Laurentius A Pramono, Laurentius A Laurentius Aswin Pramono Laurentius Aswin Pramono Laurentius Lesmana Laurentius Lesmana Leonard Nainggolan Leonard Nainggolan Leonita Ariesti Putri Listya, Luh Putu Luciana Budiati Sutanto Luciana Budiati Sutanto Luh Putu Listya Lusy Erawati Lusy Erawati Lydia D Simatupang M Purnomo Isnaeni Marcellus S Kolopaking Marcellus S. Kolopaking Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata K Marcellus Simadibrata Kolopaking Marthino Robinson Mazni, Yarman Menaldi Rasmin Moch Ikhsan Mokoagow Murdani Abdulah Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Nata Pratama Nikko Darnindro Nikko Darnindro Nikko Darnindro Novie Rahmawati Zirta Nugroho, Prionggodigdo Nunung Ainur Rahmah Nur Rasyid Nur Rasyid Nurul Akbar Nurul Akbar Oktaramdani, Tessa Paulus Kusnanto Phang, Beatrice Belinda Pringgodigdo Nugroho, Pringgodigdo Prionggodigdo Nugroho Purwita W Laksmi, Purwita W Puspita, Florentina Caroline Putri, Leonita Ariesti Rabbinu Rangga Pribadi Radhiyatam Mardhiyah Radhiyatam Mardhiyah, Radhiyatam Rahardja, Cindy Ralph Girson Ralph Girson Gunarsa Randy Adiwinata Randy Adiwinata, Randy Ranty, Stefanus Satrio Rasco Sandy Sihombing, Rasco Sandy Rasidi, Josephine Resti Mulya Sari Riadi Wirawan Riadi Wirawan Riahdo Saragih Rino A Gani Rino A Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rio Zakaria Rio Zakaria Rio Zakaria Rolan Sitompul Rudi Putranto Ryan Herardi Ryan Ranitya Sari, Cut Yulia Indah Sayid Ridho Sedijono Sedijono Seri Mei Maya Ulina Sheila Adiwinata Simon Salim Siti Setiati Siti Setiati Stefanus Satrio Ranty Stella Evangeline Bela Stephanie Dewi, Stephanie Steven Sumantri Suhendro - - Suhendro Suhendro Suhendro Suhendro Suhendro Suwarto, Suhendro Sumaryono Sumaryono Sumaryono Sumaryono Suryantini Suryantini Suryantini Suryantini Suwito Indra Suzana Ndraha Syafruddin A. R. Lelosutan Taufiq Taufiq Taufiq Taufiq Teguh Hardjono Tena Djuartina, Tena Tessa Oktaramdani Timoteus Richard Timoteus Richard, Timoteus Tito Ardi Titos Ahimsa Tjahjadi Robert Tedjasaputra Toman L Toruan Tommy P Sibuea Tri Isyani Tungga Dewi Vera D Yoewono Vera Yoewono Vera Yuwono Wardhana, Agasjtya Wisjnu Willy Brodus Uwan Willy Brodus Uwan, Willy Brodus Wina Sinaga Wirasmi Marwoto Wirasmi Marwoto Wulyo Rajabto

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