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All Journal Jurnal Gizi dan Pangan Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Journal of Nutrition College Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Biomedicine and Translational Research Indonesian Journal of Human Nutrition Jurnal Media Gizi Indonesia (MGI) Sari Pediatri Medical Laboratory Technology Journal GIZI INDONESIA Wikrama Parahita : Jurnal Pengabdian Masyarakat AcTion: Aceh Nutrition Journal Jurnal Gizi Klinik Indonesia Indonesian Food Science and TechnologyJournal Jurnal Kesehatan Prima Amerta Nutrition Canrea Journal: Food Technology, Nutritions, and Culinary Journal Journal of Telenursing (JOTING) Journal SAGO Gizi dan Kesehatan MEDIC MEdical Dedication Diversity: Disease Preventive of Research Integrity Journal of Health and Nutrition Research Jurnal Ilmiah Ilmu Terapan Universitas Jambi Electronic Journal Scientific of Environmental Health And Diseases Jurnal Penyakit Dalam Indonesia Neurona Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Jurnal Info Kesehatan
Ahmad Syauqy
Department Of Nutrition Science, Faculty Of Medicine, Universitas Diponegoro
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Sorghum Tempeh Enteral Formula Reduces Inflammatory (IL-6) and Thrombotic (PAI-1) Markers in Atherogenic Diet-Induced Rats Bintang, Francisca Natalia; Resti, Nina; Lestari, Endang Sri; Muniroh, Muflihatul; Anjani, Gemala; Syauqy, Ahmad; Djamiatun, Kis; Afifah, Diana Nur
Media Gizi Indonesia Vol. 21 No. 2 (2026): MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v21i2.185-195

Abstract

Atherosclerosis is predominantly an inflammatory process that is the key pathophysiological cause of ischemic coronary heart disease (CHD). Some studies suggest that sorghum can reduce atherosclerotic parameters through many biological activities, such as antioxidant, anti-inflammation, and anti-thrombotic properties. The primary objective was to evaluate the effect of an enteral sorghum tempeh formula on the levels of Plasminogen Activator Inhibitor-1 (PAI-1) and Interleukin-6 (IL-6) in an atherosclerotic rat model. A total of 24 male rats were utilized, with the experiment structured into an 8-week atherogenic diet induction period, followed by a 4-week intervention phase. The rats were divided into four groups: a healthy control, an atherogenic control, and two treatment groups supplemented with the formula at 0.75g/200 g and 1.50g/200 g body weight (BW), respectively. IL-6 and PAI-1 levels were quantified using Enzyme-Linked Immunosorbent Assay (ELISA). The atherogenic diet successfully induced a significant elevation in both IL-6 and PAI-1 levels compared to the healthy control group (p=0.000), indicating a heightened inflammatory and thrombotic state in the atherosclerotic group. Conversely, the groups receiving the sorghum tempeh-based formula exhibited a significant reduction in both IL-6 and PAI-1 levels compared to the atherogenic control group (p=0.000), suggesting potent anti-inflammatory and antithrombotic properties of the sorghum tempeh.
EFEK VITAMIN D TERHADAP KADAR HbA1c PADA T2DM : NARATIF REVIEW Ihda Hanifatun Nisa; Etika Ratna Noer; Adriyan Pramono; Ahmad Syauqy; I Edward Kurnia Setiawan Limijadi
Journal of Nutrition College Vol 15, No 1 (2026): Januari
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jnc.v15i1.49638

Abstract

ABSTRACTBackground: Type 2 Diabetes Mellitus (T2DM) is characterized by hyperglycemia and insulin resistance with HbA1c as the main indicator. Vitamin D plays a role in glucose metabolism through modulation of insulin sensitivity and anti-inflammatory effects, but the relationship between vitamin D and HbA1c still shows varied results. Objective: This review aims to analyze the effect of vitamin D on HbA1c levels in T2DM patients based on published studies. Methods: This study is a narrative review was conducted by searching databases including PubMed, ScienceDirect, and Google Scholar over the past 10 years. Screening using Mendeley application yielded 10 articles meeting the criteria. Variables studied included HbA1c levels, simple carbohydrate intake, fiber intake, vitamin D intake, and oral hypoglycemic agent adherence.Results Several studies show that vitamin D can reduce HbA1c levels through increased insulin sensitivity and reduced inflammation. However, other studies report no significant effect of vitamin D on HbA1c, especially in individuals with sufficient vitamin D levels. Conclusion: Vitamin D potentially plays a role in controlling HbA1c levels in T2DM patients, especially in individuals with vitamin D deficiency. Further research with more rigorous designs is still needed to confirm the effect of vitamin D on HbA1c.Keywords: Type 2 diabetes mellitus; HbA1c; inflammation; insulin sensitivity; vitamin d  ABSTRAKLatar Belakang: Diabetes Mellitus Tipe 2 (T2DM) ditandai dengan hiperglikemia dan resistensi insulin dengan HbA1c sebagai indikator utama. Vitamin D berperan dalam metabolisme glukosa melalui modulasi sensitivitas insulin dan efek anti-inflamasi, namun hubungan antara vitamin D dan HbA1c masih menunjukkan hasil bervariasi. Tujuan: Menganalisis efek vitamin D terhadap kadar HbA1c pada penderita T2DM berdasarkan studi yang telah dipublikasikan. Metode: Tinjauan naratif dilakukan dengan menelusuri basis data PubMed, ScienceDirect, dan Google Scholar dalam 10 tahun terakhir. Screening menggunakan aplikasi Mendeley menghasilkan 10 artikel yang sesuai kriteria. Variabel yang diteliti meliputi kadar HbA1c, asupan karbohidrat sederhana, asupan serat, asupan vitamin D, dan kepatuhan minum OHO. Hasil: Beberapa studi menunjukkan vitamin D dapat menurunkan kadar HbA1c melalui peningkatan sensitivitas insulin dan pengurangan peradangan. Namun, beberapa penelitian lain melaporkan tidak ada efek signifikan dari vitamin D terhadap HbA1c, terutama pada individu dengan kadar vitamin D cukup. Kesimpulan: Vitamin D berpotensi berperan dalam pengendalian kadar HbA1c pada penderita T2DM, terutama pada individu dengan defisiensi vitamin D. Penelitian lebih lanjut dengan desain lebih ketat masih diperlukan untuk memastikan efek vitamin D terhadap HbA1c.Kata Kunci: Diabetes mellitus tipe 2; HbA1c; inflamasi; sensitivitas insulin; vitamin d  
PERAN FITOKIMIA EKSTRAK UMBI SARANG SEMUT (GENUS MYRMECODIA) TERHADAP POTENSINYA SEBAGAI AGEN ANTIDIABETES MELITUS TIPE 2 : NARRATIVE REVIEW Yama Dharma Putera; Ahmad Syauqy
Journal of Nutrition College Vol 15, No 3 (2026): Juli
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jnc.v15i3.51165

Abstract

ABSTRACTBackground: The availability of natural plants as an alternative treatment for DMT2 is widespread in Indonesia. The genus Myrmecodia is one of the plants that has long been used as a traditional medicine by local Papuan people to cure cancer and diabetes.Objectives: This article will review studies related to the genus Myrmecodia regarding phytochemical content, its potential as an antioxidant agent and antidiabetes mellitus type 2.Methods: This narrative review synthesized 119 references from ScienceDirect, PubMed, Frontiers, SpringerLink, Google Scholar, and other respected journal publishers.Results: Ant nest/ Myrmecodia tubers have the potential as a source of antioxidants as evidenced by their antioxidant activity being classified as very strong (IC₅₀ < 50 ppm), have antidiabetic potential by being able to inhibit the α-glucosidase enzyme, improve insulin sensitivity and secretion, and protect β-cells, although specifically several specific molecular mechanisms of action are not yet known.Conclusion: Ant nest tuber has the potential as an additional therapy in type 2 diabetes to control blood sugar and provide antioxidant protection. Although preclinical data supports it, clinical research is needed to confirm its safety and effectiveness. Standardization of extracts and dose-response testing in humans are important next steps for the development of phytotherapy for type 2 diabetes mellitus.Keywords : Myrmecodia; ant nest; antioxidant; antidiabetes ABSTRAKLatar belakang: Ketersediaan tanaman alami sebagai alternatif pengobatan DMT2 tersebar luas di Indonesia. Genus Myrmecodia merupakan salah satu tanaman yang telah lama digunakan sebagai pengobatan tradisional masyarakat lokal Papua untuk menyembuhkan kanker dan diabetes.Tujuan: Artikel ini akan mengulas studi yang berkaitan dengan genus Myrmecodia mengenai kandungan fitokimia, potensinya sebagai agen antioksidan dan antidiabetes melitus tipe 2.Metode: Sumber informasi ilmiah mengambil 119 referensi yang berasal dari database literatur ilmiah online, termasuk Science Direct, PubMed, Frontiers, Springer, Google Scholar dan penerbit jurnal lain yang terkemuka.Hasil: Umbi sarang semut/Myrmecodia menunjukkan potensi sebagai sumber antioksidan yang dilaporkan dengan aktivitas antioksidannya tergolong sangat kuat (IC₅₀ < 50 ppm), memiliki potensi antidiabetes dengan cara mampu menghambat kerja enzim α-glukosidase, memperbaiki sensitivitas serta sekresi insulin, dan melindungi sel-β, meski secara spesifik beberapa mekanisme kerja molekuler secara spesifik belum diketahui.Simpulan: Umbi sarang semut/Myrmecodia berpotensi sebagai terapi tambahan pada diabetes tipe 2 untuk mengontrol gula darah dan memberikan perlindungan antioksidan. Meski data praklinis mendukung, diperlukan penelitian klinis untuk mengkonfirmasi keamanan dan efektivitasnya. Standardisasi ekstrak dan uji dosis-respons pada manusia menjadi langkah penting berikutnya untuk pengembangan fitoterapi diabetes melitus tipe 2.Kata Kunci: Myrmecodia; sarang semut; antioksidan; antidiabetes; spesies oksigen reaktif (ROS)
COMMUNITY-BASED OBESITY EDUCATION USING AUDIOVISUAL MEDIA TO ENHANCE KNOWLEDGE Enis, Rina Nofri; Shafira, Nyimas Natasha Ayu; Herlambang, Herlambang; Syauqy, Ahmad; Fitri, Amelia Dwi; Puspasari, Anggelia; Maharani, Citra; Kusdiyah, Erny; Aurora, Wahyu Indah Dewi; Delfira, Annissa; Sulistiawan, Andika; Arisya, Qothrunnada
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 9 No. 1 (2026): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Obesity is a growing public health concern associated with an increased risk of non-communicable diseases. Improving public knowledge through health education is an important strategy for promoting healthy lifestyles and preventing obesity. Audiovisual media have been widely adopted to enhance educational effectiveness and participant engagement. Objective: This study evaluated the effectiveness of a community-based obesity education program using PowerPoint presentations and an educational video to improve participants' knowledge. Methods: A pre-experimental one-group pretest–posttest design was conducted among community participants in Jambi, Indonesia, in 2026. Participants completed a 10-item multiple-choice questionnaire before and after the educational session. The intervention covered the definition of obesity, body mass index classification, waist circumference, risk factors, complications, and lifestyle-based prevention strategies. Data were analyzed using the Shapiro–Wilk test and the Wilcoxon signed-rank test, with statistical significance set at p < 0.05. Results: Forty-five participants completed both assessments. The mean knowledge score increased from 86.67 ± 12.25 at baseline to 94.89 ± 6.95 after the intervention. The distribution of score differences was non-normal (Shapiro–Wilk: W = 0.749, p < 0.001). The Wilcoxon signed-rank test demonstrated a significant improvement in knowledge following the educational intervention (W = 0, p < 0.001). Participant evaluation also indicated high acceptance of the educational program across all assessed domains, including material quality, video presentation quality, perceived educational benefits, and overall participant satisfaction. Conclusion: The community-based obesity education program effectively improved participants' knowledge and was well accepted by the participants. Integrating presentations with audiovisual media represents a practical approach to strengthening health literacy and supporting community-based obesity prevention. Keywords: audiovisual education; obesity; community intervention; health promotion; knowledge.
Co-Authors ,Adriyan Pramono Adriyan Pramono Adriyan Pramono Amatullah, Afifah Amatulloh Dewi Fajar Amelia Dwi Fitri, Amelia Dwi Amelia, Wita Rizki Anang M Legowo Andika Sulistiawan Angga Rizqiawan Anggelia Puspasari Angraresti, Irfa Eka Ani Margawati Anjani, Gemala Annastasia Ediati Annissa Delfira Apoina Kartini Arfinanda, Najwa Diva Khoirunnisa' Ari Wijayanti Ari Wijayanti Arisanti, Yohanete Novita Arisya, Qothrunnada Armaidi Darmawan Arwinda Nugraheni Aryu Candra Asro Hayani Harahap Astika Widy Utomo, Astika Widy Astrine Permata Leoni Astrine Permata Leoni Astrine Permata Leoni Astrine Permata Leoni ATTIYA ISTARINI Ave Olivia Rahman Avionita Latuihamallo Ayu Rahadiyanti Ayustaningwarno , Fitriyono Batubara, Astriana Marta Befi - Sundari Befi Sundari Binar Panunggal Bintang, Francisca Natalia BR Purba, Martalena Chairina, Ade Chatarina Umbul Wahyuni Choirun Nissa Choirun Nissa Citra Maharani Cut Arsyiyanti Daniartama, Bela Deny Yudi Fitranti Dewanti Dewanti Dewi Marfu’ah Kurniawati dewi, hasna Diana Nur Afifah, Diana Nur Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ekaputri, Tia Wida Ekowati Chasanah Endang Mahati Endang Sri Lestari Endang Yuli Purwani, Endang Yuli Enny Probosari Erisca Ayu Utami Ermy Liesma Saputri Erny Kusdiyah Etika Ratna Noer Etika Ratna Noer Etisa Adi Murbawani Fairuz Quzwain Fairuz, Fairuz Fajrani, Alifia Mukti Fajrani, alifiaA muktiM Faradina, Amelia Farid Agung Rahmadi, Farid Agung Fillah Fithra Dieny Fillah Fithra Dieny Fitrah Ernawati Fitriyono Ayustaningwarno Furkaniaty, Annisa Gading, Patrick William Hanani, Ruth Hanina, Hanina Harahap, Huntari Hartanti Sandi Wijayanti Hasmita, Debby Hasna Dewi Herlambang HERLAMBANG HERLAMBANG Hidayati Hidayati Hindarta, Nadhea Alriessyanne Humaryanto, Humaryanto Humaryanto, Humaryanto I Edward Kurnia Setiawan Limijadi Ihda Hanifatun Nisa Ilmiati, Fatia Ima Maria Irawan Anasta Putra, Irawan Anasta Irma Nur Amelia Jaswir, Irwandi JMJ, Jurnal Justitia, Budi Juwita, Riza Iska Karina Nabila Yasmin Kedang, Veronika Merika Kis Djamiatun Kusmiyati Tjahjono Kusmiyati Tjahjono Kusmiyati Tjahjono Laura, Cicilia Leoni, Astrine Permata Lestari, Rahma Wati Dwi Lilis Endang Wijayanti, Lilis Endang Lipinwati ., Lipinwati Lisa, Mei Lora Sri Nofi Lora Sri Nofi Lora Sri Nofi Lydia Ratnadewi Wiragapa MADE ASTAWAN Maharani, Mutiara Irma Majdiyyah, Munifa Maria Martiani Maria Mexitalia Maria, Ima Martalena Br Purba MARTHA ARDIARIA Masha, Tania Mattarahmawati, Siti Andhini Miftahurrahma, Miftahurrahma Miftahurrahmah Miftahurrahmah, Miftahurrahmah Mita Arini Mita Arini Moesijanti Yudiarti Endang Soekatri mukhamad khumaidi usman Muniroh, Muflihatul Mursid Tri Susilo Nafisah Nawai, Fatmayanti Niken Puruhita Nilatul Izah, Nilatul Nissa, Choirun Novitasari, Anggi Nugraheni, Dini Nur Afifah, Diana Nur Indah Kartikasari Nuri Lydia Rahma Nuriyah, Nuriyah Nurjanah, Ayu Nurmasari Widyastuti Nuryanto Nuryanto Nyimas Natasha Ayu Shafira Paramitasari Tri Wahyuni, Paramitasari Tri Perdanawati, Mia Permatasari, Mayang Januarti Pratiwi, Syafira Noor Pravita Dewi Suhada Prayoga, Edwin Agung Purba, Martalena Br. Purwita Wijaya Laksmi Purwita Wijaya Laksmi Putri Sari Wulandari R. Farah Amalia Rachma Purwanti Rahardiyanti, Ayu Rahma Wati Dwi Lestari Rahma, Devi Elvina Rahmawati, Irma Sarita Rahmawati, Siti Irma Ratih Paramastuti Ratnayani Resti, Nina Ria Indra Cahyanti Rina Nofri Enis Rita Halim Rizqiawan, Angga RR. Ella Evrita Hestiandari Rusdaina Rusdaina, Rusdaina Rusyanto, Widya Samichah Samichah Saputra, Ikmal Galih Sari Puspitasari A.P, Sari Setyawan, Fajar Setyawati, Amalia Rani Setyawati, Ba'ul Seventina Nurul Hidayah, Seventina Nurul Sherlin Regina Jami Siringoringo, Ester Theresia Siti Fatimah Muis Siti Fatimah-Muis Siti Fatimah-Muis Siti majidah Siti Nur Hidayati Sri Achadi Nugraheni Suhardi . Suhardi . Susetyowati Suzan, Raihanah Syahadah, Muti'ah Mustaqimatusy Tarawifa, Susan Tengku Arief Buana Perkasa Tika Yeni Rachmawati Tsani, A. Fahmy Arif Utami, Erisca Ayu Vanessa Yudha Azizul Ilmi Wahyu Indah Dewi Aurora Welresna Juliatri Putri Rupiasa Widya, Fiona Christina Wita Rizki Amelia Wita Rizki Amelia Wita Rizki Amelia Wita Rizki Amelia Yama Dharma Putera Yanti Ernalia Yenni, Fitri Zhu, Fan Zulfa, Fairuz