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Perbedaan Pengetahuan dan Sikap Masyarakat Terhadap Pemberian Booklet dan Video Dagusibu Antibiotik Madania Madania; Nur Rasdianah; Nur Ain Thomas; Faramita Hiola; Sri Nur'ain E. Ahmad
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.15547

Abstract

Inappropriate use of antibiotics is common in the world, both in the community and in the hospital environment, which can lead to antibiotic resistance. The purpose of this study was to determine the knowledge and attitudes of the community before and after being given the booklet and video of dagusibu antibiotics and to determine the differences and influence of community knowledge and attitudes towards the administration of the booklet and video of the dagusibu antibiotic in Lopo Village, Batudaa Pantai Sub-District, Gorontalo Regency. This research applied a quasi-experimental design with the provision of booklets and videos before and after being given education. The number of samples was 74 which were taken using non-probability sampling technique. Research data were analyzed using Wilcoxon test and Man-Whitney test. The results showed that most of the community's knowledge before being given education was still in the sufficient category (57% booklet and 62% video), and the community's attitude was in the negative category (73% booklet and 84% percent video). Meanwhile, after being given education, the community's knowledge had increased to a good category (72% booklet and 86% videos), and community's attitudes had increased to a positive category (93% booklets and videos 98%) as well. Therefore, it can be concluded that there was a significant effect on increasing knowledge and attitude after being given booklets and videos (P0.1), and there was no significant difference between giving booklets and videos on increasing community’s knowledge and attitudes (P0.1).
Variasi Konsentrasi Bahan Pengikat Dari Pati Biji Durian (Durio Zibethinus)Terhadap Mutu Fisik Pada Formulasi Tablet Hisap Vitamin C Nur Ain Thomas; Fika Nuzul Ramadhani; Juliyanti Akuba; Ariani H. Hutuba
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.4317

Abstract

Starch of durian (Durio Zibethinus) seed is an accessible potential material to be utilized as binding agent in tablet. This study attempts to discover the influence of starch concentrate of durian seed in different percentages, i.e., 20%, 25%, and 30%, as binding agent towards the physical quality (by conducting tests i.e. weight uniformity test, hardness test, friability test, dissolution test, and organoleptic evaluation) towards vitamin C lozenges tablet formulation. Three formulae with different durian seed concentrate variation of F1 (20%), F2 (25%), and F3 (30%) were applied during the formulation of vitamin C lozenges. The result indicates that F2 and F3 formulae fulfilled all the test conducted, while the F1 formula only passed the weight uniformity test, taste response test, and organoleptic test. Based on the results of the study, F3 fulfilled all evaluations carried out, namely F3 4.07 kg hardness test, 0.30% friability test, 443.3 seconds dissolution test. F2 hardness test 3.79 kg, fragility test 0.34% solubility test 402 seconds. F1 hardness test 3.17 kg, fragility test 1.33%, soluble time test, 302.3 seconds. the conclusion obtained from the ANOVA-One way test is that there is a significant disintegration time difference of all formulas and continued by the Post-Hoct test to see the comparison of each formula with a confidence level (95%).
Edukasi Penggunaan Obat Antidiabetes di Bulan Ramadhan pada Masyarakat Desa Buata Kecamatan Botupingge Widy Susanti Abdulkadir; Nur Ain Thomas; Dizky Ramadani Putri Papeo
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 1 (2022): Vol 1 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (909.881 KB) | DOI: 10.3731/phar.soc.v1i1.14039

Abstract

Permasalahan utama pasien Diabetes Melitus (DM) adalah kepatuhan dalam minum obat dalam jangka Panjang. Pasien diabetes melitus yang mendapat terapi obat antidiabetes oral yang dapat menjalankan ibadah puasa di bulan Ramadhan harus mengikuti aturan baru minum obat, sehingga perlu diberikan informasi mengenai aturan minum obat yang tepat. Pemberian informasi melalui penyebaran brosur merupakan salah satu cara yang paling efektif untuk memperkenalkan aturan pemberian obat yang benar. Kegiatan tersebut berlokasi di Desa Buata, Kecamatan Botupingge, Kabupaten Bone Bolango. Hasil dari kegiatan ini, penderita diabetes melitus lebih siap menghadapi Ramadhan dengan aturan baru minum obat anti diabetes.
Edukasi dan Inovasi Keripik Bayam Sehat sebagai Alternatif Pangan Ibu Hamil Pencegah Anemia Nur Ain Thomas; Endah Nurrohwinta Djuwarno; Susanti Pakaya
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 3 (2022): Vol 1 Edisi 3 (2022)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (589.561 KB) | DOI: 10.3731/phar.soc.v1i3.18630

Abstract

Anemia   pada   ibu   hamil   berdampak   buruk   bagi   ibu   maupun   janin. Kemungkinan dampak buruk  terhadap ibu hamil yaitu proses persalinan yang membutuhkan waktu lama dan mengakibatkan perdarahan serta syok akibat kontraksi. Dampak buruk pada janin yaitu terjadinya    prematur, bayi lahir berat  badan rendah, kecacatan bahkan kematian bayi. Pengabdian ini bertujuan untuk  menghasilkan  produk  inovasi  yang  dapat  membantu  mengatasi  masalah anemia pada ibu hamil berupa pembuatan keripik bayam sehat. Pembuatan keripik bayam ini bertujuan untuk meningkatkan minat ibu hamil dalam mengkonsumsi sayuran yang kaya gizi dan dapat mencegah anemia disaat hamil. Kegiatan pengabdian kepada masyarakat ini bertujuan agar dapat mencegah kejadian anemia pada ibu hamil pada umumnya dan mencegah stunting pada anak pada khususnya. Pengabdian ini dilakukan dengan cara memberikan edukasi langsung mengenai pentingnya menghindari anemia disaat hamil pada ibu di saat posyandu ibu hamil dan membagikan keripik bayam sehat pada ibu hamil yang hadir. Pemberian edukasi dan pembagian keripik bayam pada masyarakat desa Bongohulawa khususnya ibu hamil mendapatkan respon yang baik karena sebagian besar masyarakat memiliki atensi yang tinggi melalui pertanyaan dan sangat menyukai produk olahan keripik bayam. Pengabdian ini memberikan manfaat yang besar bagi masyarakat desa agar mendapatkan pengetahuan mengenai manfaaat menghindari keadaan anemia disaat hamil dan memberikan informasi terkait produk olahan keripik bayam sehat.
Isolasi, Karakterisasi, dan Uji Antioksidan Fungi Endofit dari Tanaman Batang Kunyit (Curcuma domestica Val.,) Mahdalena Sy. Pakaya; Nur Ain Thomas; Hamsidar Hasan; Ariani H. Hutuba; Grasela Mbae
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.20341

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Endophytic fungi live in mutualistic symbiosis and can produce secondary metabolites similar to their host. This research aims to isolate, characterize, and test the antioxidant activity of secondary metabolites from turmeric stems. This research is experimental research where the method used for endophytic fungi isolation is the direct planting method, and antioxidant activity is tested using qualitative and quantitative methods with DPPH (1.1-diphenyl-2-picylhydrazyl). One fungal isolate was obtained with the fungal isolate code (BK). Based on macroscopic and microscopic characterization, the BK fungal isolate indicates the Deuteromycota class's characteristics. The qualitative antioxidant test results indicate that the fraction of BK endophytic fungal isolate indicates antioxidant activity, indicated by the yellow color against a purple background on the TLC plate observed under visible light. The respective ICso values for the ethyl acetate and n-hexane fractions were 52.989 µg/ml and 89.725 µg/ml, categorized as strong antioxidants. The methanol fraction had an ICso value of 119.02 µg/ml, categorized as moderate, while the pure supernatant fraction had an ICso value of 156.86 µg/ml, categorized as weak antioxidant activity.
Uji Penyembuhan Luka Bakar Gel Enzim Bromelin Menggunakan Carbopol 940 Secara In Vivo Nur Ain Thomas; Muhammad Taupik; Endah Nurrohwinta Djuwarno; Dizky Ramadani Putri Papeo; Nabila Novreini Djunaidi
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.20364

Abstract

Bromelain is a proteolytic enzyme or natural protease found in tissues, including the stem, fruit, and leaves of pineapple (Ananas comosus var. comosus) and other plant species of the Bromeliaceae family. Bromelain is known as an efficient debdriding agent because it is beneficial in  burn healing and tissue regeneration. This research aims to determine the effectiveness of bromelain enzyme for burns wounds in rabbits (Oryctolagus cuniculus). This research began with the optimization of carbopol 940 base preparations with variations in concentration, namely Formula 1 (F1) for 0,5%, Formula 2 (F2) for 1%, and Formula 3 (F3) for 1,5%. The evaluation of the gel formulation includes an organoleptic test, homogeneity test, pH test, viscosity test, adhesive force test, and spreadability test. The evaluation result indicates the base concentration in Formula 1 (F1) at 0,5% has met the requirements for a gel preparation. Formula 1 (F1) for 0,5, then combined with varying concentration of bromelain, namely Formula 1A (0,1%), Formula 1B (0,5%), and Formula 1C (1%). The gel formulation wa re-evaluated, including an organoleptic test, homogeneity test, pH test, viscosity test, adhesion test, spreadability test, irritation test, and in vivo test. In vivo effectiveness testing and irritation testing were conducted on five treatment groups, namely a positive control group (Bioplacenton®), Formula 1A (0,1%), Formula 1B (0,5%), Formula 1C (1%), and a group without treatment, then observed for 15 days. The observation data were processed using the One Way ANOVA test. Based on the results of the irritation test, Formula 1A (0,1%). Formula 1B (0,5%) and Formula 1C (1%) did not cause skin irritation. In the in vivo test, Formula 1C (1%) indicated the fastest recovery compared to other treatment groups, as evidenced by the decrease in wound diameter and visual observation, where the wound had started to close completely on day 15 of observation.
Pengaruh Konsentrasi Carbopol 940 Sebagai Gelling Agent Terhadap Stabilitas Fisik Sediaan Gel Lidah Buaya (Aloe Vera) Nur Ain Thomas; Robert Tungadi; Faramita Hiola; Multiani S. Latif
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.18050

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Carbopol 940 is a gelling agent that is very communly used in cosmetic production because of its high compatibility and stability, and it is non-toxic when applied to the skin and it spreads on the skin more easilym gels are semi solid preparations that contain a gel-forming agent which gives stiffiness to collodial solutions or dispersions used for external use on the skin, gel preparations are widely chosen because they are very easy to apply ( easily smeared, absorbed, and cleaned) and more attractive (transparent) compared to the other topical preparations. the purpose of this study was to determine the effect of carbopol concentration 940 as a gelling agent on the physical stability of aloe vera gel preparations. this study began with optimization of the carbopol 940 gel base then the preparation formulation used 50% aloe vera extract, 0,5% carbopol 940 F1, 1 % F2, 2% F3, 10 % propylene glycol, 10% glycerine, 0,1% dm dm hydantoin and sufficient aquadest, afterward the evaluation of the preparation included organoleptic, observations, homogeneity tests, pH tests, spreadability tests, adhesion tests and viscosity tests. carbopol 940 was depeloped using co-free water. gel preparations were 0,5%, 1%, and 2%. the results showed that the thrid formulation (F3) with a concentration of 2% fulfilled the physical evaluation requirements for organoleptic, spreadability, adhesion, viscosity, pH and homogeneity tests.
Purchase Profile of Hypertension Drugs of Calcium Channel Blocker Group Amlodipine Doses of 5 mg and 10 mg in Several Gorontalo City Pharmacies January - March period in 2024 Paneo, Mohamad Aprianto; Thomas, Nurain Ain; Latif, Multiani S; Pido, Nur Huda
Jambura Nursing Journal Vol 6, No 2: July 2024
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jnj.v6i2.25339

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Hypertension is one of the most common diseases in Indonesia, one of which in the province of Gorontalo is included in the top 10 largest diseases. According to the health data profile from the Gorontalo provincial health office in 2022, the level of hypertension in Gorontalo city reached 2,325 cases, or around 4.6%. High cases of hypertension must be balanced with the provision of hypertension drugs, one of which is the calcium channel blocker (CCB) hypertension drug, amlodipine. The purpose of this study was to see the profile of purchasing hypertension drugs from the Calcium Channel Blocker (CCB) Amlodipine group in the community in Gorontalo City, especially in pharmacy and pharmaceutical service facilities. The research method uses a random sampling observation method, namely to see drug purchases in three Gorontalo city pharmacies located in different sub-districts. Purchase tracking was carried out in January, February, and March 2024. The results showed the purchase of amlodipine drugs in the three pharmacies in different amounts. Pharmacy B dominated the purchase of drugs compared to Pharmacy A and Pharmacy C at the 5 mg and 10 mg doses, respectively. Based on the results obtained, these differences are influenced by several indicators, including drug availability, drug completeness, pharmacy strategic location, and customer satisfaction.
Peningkatan Kesadaran Tentang Side Effect Of Herbal Medicine Pada Masyarakat Di Kelurahan Hutuo Kabupaten Gorontalo Tuloli, Teti Sutriyati; Thomas, Nurain; Latif, Multiani S; Zulfiayu, Zulfiayu
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 3, No 3 (2024)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v3i3.27587

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Obat tradisional yang digunakan untuk meningkatkan imunitas atau daya tahan tubuh telah berkembang dengan berbagai variasi bentuk. Bentuk obat tradisional yang ada saat ini seperti bubuk, cairan,tablet, rajangan, obat gosok dan lainnya. Menurut hasil Riskesdas 2018 proporsi pemanfaatan pengobatan tradisional di Provinsi Gorontalo sebanyak 25,8% dalam bentuk ramuan jadi, dan 42,6% ramuan buatan sendiri, Kota Gorontalo menempati peringkat ke-4 terbanyak proporsi pemanfaatan obat tradsional dengan jumlah 24,16% ramuan jadi dan 40,83% ramuan buatan sendiri. Tujuan pelaksaanan Kegiatan Join Kemitraan ini adalah Meningkatkan kesadaran masyarakat Kelurahan Hutuo, Kabupaten Gorontalo tentang efek samping obat herbal serta memotivasi masyarakat untuk lebih waspada terhadap kejadian efek samping obat herbal. Kegiatan Join Kemitraan ini dilaksanakan melalui edukasi dan sosialisasi tentang pentingnya kesadaran Masyarakat akan kejadian efek samping obat .Program Kegiatan Join Kemitraan ini dilaksanakan mulai 2 September 2024 di Desa Hutuo, Kabupaten Gorontalo dengan jumlah peserta sebanyak 30 orang Masyarakat Desa Hutuo, Kabupaten Gorontalo. Adanya sinergitas yang baik antara Aparat desa, Kader Kesehatan, Masyarakat desa dan Tim dari Dosen dan Mahasiswa maka seluruh program pengabdian join kemitraan dapat terlaksana dengan baik dan sukses guna mewujudkan Kelurahan Hutuo bebas dari efek samping obat herbal.
Inovasi Pembuatan Produk Kesehatan Berbasis Jagung Sebagai Komoditas Lokal Dalam Upaya Peningkatan Derajat Kesehatan Dan Kesejahteraan Masyarakat Desa Motolohu Kecamatan Randangan Pohuwato Hasan, Hamsidar; Madania, Madania; Thomas, Nur Ain; Paneo, Mohamad Aprianto
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 3, No 3 (2024)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v3i3.27353

Abstract

Jagung adalah salah satu komoditas terbesar di daerah Motolohu. Pemanfaatan jagung Selain menjadi pakan ternak, jagung banyak diolah menjadi berbagai bahan makanan mulai dari makanan ringan, tepung hingga minyak rendah kolesterol. Tak hanya itu, komoditi pangan ini juga bisa dinikmati secara langsung dengan cara direbus, dibakar atau dibuat beras jagung. Pemanfaatan sebagai beras jagung yang biasanya dijual Rp 10.000 perliter masih sangat rendah nilainya dan kurang diminati oleh masyarakat. Untuk dapat meningkatkan nilai jual maka perlu inovasi bagaimana membuat produk kesehatan yang lebih tinggi nilai gizinya dan nilai jualnya sehingga dapat meningkatkan derajat kesehatan dan kesejahteraan masyarakat. Pengabdian ini bertujuan memberikan pengetahuan dan keterampilan dalam membuat produk kesehatan dari jagung seperti brownies jagung, keripik jagung, susu jagung dan lain-lain. Metode pemberdayaan dan transfer ilmu adalah metode pendampingan dan praktek langsung mulai dari penyiapan bahan baku sampai pada produk jadi dan juga bagaimana cara pemasarannya. Sasaran pengabdian ini adalah ibu-ibu PKK dan ibu rumah tangga yang berdominsili di Desa Motolohu. Hasil pendampingan ini menunjukkan masyarakat sangat menyukai produk kesehatan seperti brownies dan brinchese, dan sangat senang dan puas dengan pendampingan seperti ini. Produk berbahan baku jagung ini mengandung serat, karbohidrat, protein dan vitamin, serta bersifat sebagai antioksidan. Analisis kelayakan usaha  menunjukkan  produk berbasis jagung bisa meningkatkan pendapatan masyarakat. 
Co-Authors Abas, Siti Nur Rahmatiya Abto, Nazarudin Adam Mustapa, Mohammad Akuba, Julianti alkatiri, ahmad alkatiri Alpian Panu, Muhamad Andi Makkulawu Anggai, Rifka Anggraini Anggun Sasmita Ibrahim Ar’syifa Wijaya, Hudan Ariani H. Hutuba Arista Idris, Pinkan Astuti, Zulfa Amalia Bakari, Mohamad Fadly Basri, Rakhmadana Fitraeni Bioto, Yakob Datu, Novanza L.M.N Devie Ariany Daud Dr. Apt. Hamsidar Hasan S.Si.,M.Si Dwy Jayanto Palay, Rendy Ekawaty Prasetya Endah Nurrohwinta Djuwarno Faradila Ratu Cindana Fika Nuzul Ramadhani Fujiana Abd Karim Gita Potabuga Grasela Mbae Hamsidar Hamsidar Hamsidar Hasan Harwanto, Yelisnawati Hiola, Faramita Hutuba, Ariani Ishak Isa Julianty Akuba Kahar, Oktaviani LATIF, MULTIANI S Latif, Multiani S. Madania Madania, Madania Madania, Madania Mahdalena Sy Pakaya Makkulawu, Andi Malopo, Ekaria Revalya Mamu, Safira Mahadewi Manno, Mohamad Reski Maryadi Moh. Rivai Nakoe Mohamad Adam Mustapa Mohamad Aprianto Paneo Mohi, Mega Agustiwi Moo, Faradila Ratu Cindana Mo’o, Faradila Ratu Cindana Muhammad Taupik Muhammad Taupik Multiani S Latif Mumtazah, Naharil Nabila Novreini Djunaidi Nakii, Siti Fatmawaty Nur Oktaviana Nur Rasdianah Pakaya, Juniarista Jessica Pakaya, Lutfiah Pakaya, Nikmasari Papeo, Dizky Ramadani Putri Pido, Nur Huda Puluhulawa, Lisa Efriani Rahmatia Is. Kaluku Rismayani, Nur Robert Tungadi Robert Tungadi Robiatun Rambe Sabrina, Putri Febbiyanti Sapiun, Zulfiayu Selvi Marcellia Sidangoli, Adiva Sri Nur'ain E. Ahmad Suleman, Putri Rawe Suleman, Windy Riani Suryadi, A. Mu'thi Andy Suryadi, A. Mu’thi Andy Suryadi, A.Mu'thi Andy Suryadi,, A. Mu'thi Andy Susanti Pakaya Teti Sutriyati Tuloli Thamrin, Rahmulia Timo, Nur Kharisma Ekaputri Tomu, Anita Faradiana Pratiwi R. Wanda Gita Van Gobel Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widysusanti A.K Wiwit Zuriati Uno Yasin, Sulistya Yayah Rachmatiyah Yuni Sarah Manoppo Zulmai Rani Zuriati Uno, Wiwit