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Perbedaan Pengetahuan dan Sikap Masyarakat Terhadap Pemberian Booklet dan Video Dagusibu Antibiotik Madania Madania; Nur Rasdianah; Nur Ain Thomas; Faramita Hiola; Sri Nur'ain E. Ahmad
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.15547

Abstract

Inappropriate use of antibiotics is common in the world, both in the community and in the hospital environment, which can lead to antibiotic resistance. The purpose of this study was to determine the knowledge and attitudes of the community before and after being given the booklet and video of dagusibu antibiotics and to determine the differences and influence of community knowledge and attitudes towards the administration of the booklet and video of the dagusibu antibiotic in Lopo Village, Batudaa Pantai Sub-District, Gorontalo Regency. This research applied a quasi-experimental design with the provision of booklets and videos before and after being given education. The number of samples was 74 which were taken using non-probability sampling technique. Research data were analyzed using Wilcoxon test and Man-Whitney test. The results showed that most of the community's knowledge before being given education was still in the sufficient category (57% booklet and 62% video), and the community's attitude was in the negative category (73% booklet and 84% percent video). Meanwhile, after being given education, the community's knowledge had increased to a good category (72% booklet and 86% videos), and community's attitudes had increased to a positive category (93% booklets and videos 98%) as well. Therefore, it can be concluded that there was a significant effect on increasing knowledge and attitude after being given booklets and videos (P0.1), and there was no significant difference between giving booklets and videos on increasing community’s knowledge and attitudes (P0.1).
Variasi Konsentrasi Bahan Pengikat Dari Pati Biji Durian (Durio Zibethinus)Terhadap Mutu Fisik Pada Formulasi Tablet Hisap Vitamin C Nur Ain Thomas; Fika Nuzul Ramadhani; Juliyanti Akuba; Ariani H. Hutuba
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.4317

Abstract

Starch of durian (Durio Zibethinus) seed is an accessible potential material to be utilized as binding agent in tablet. This study attempts to discover the influence of starch concentrate of durian seed in different percentages, i.e., 20%, 25%, and 30%, as binding agent towards the physical quality (by conducting tests i.e. weight uniformity test, hardness test, friability test, dissolution test, and organoleptic evaluation) towards vitamin C lozenges tablet formulation. Three formulae with different durian seed concentrate variation of F1 (20%), F2 (25%), and F3 (30%) were applied during the formulation of vitamin C lozenges. The result indicates that F2 and F3 formulae fulfilled all the test conducted, while the F1 formula only passed the weight uniformity test, taste response test, and organoleptic test. Based on the results of the study, F3 fulfilled all evaluations carried out, namely F3 4.07 kg hardness test, 0.30% friability test, 443.3 seconds dissolution test. F2 hardness test 3.79 kg, fragility test 0.34% solubility test 402 seconds. F1 hardness test 3.17 kg, fragility test 1.33%, soluble time test, 302.3 seconds. the conclusion obtained from the ANOVA-One way test is that there is a significant disintegration time difference of all formulas and continued by the Post-Hoct test to see the comparison of each formula with a confidence level (95%).
Edukasi Penggunaan Obat Antidiabetes di Bulan Ramadhan pada Masyarakat Desa Buata Kecamatan Botupingge Widy Susanti Abdulkadir; Nur Ain Thomas; Dizky Ramadani Putri Papeo
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 1 (2022): Vol 1 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (909.881 KB) | DOI: 10.3731/phar.soc.v1i1.14039

Abstract

Permasalahan utama pasien Diabetes Melitus (DM) adalah kepatuhan dalam minum obat dalam jangka Panjang. Pasien diabetes melitus yang mendapat terapi obat antidiabetes oral yang dapat menjalankan ibadah puasa di bulan Ramadhan harus mengikuti aturan baru minum obat, sehingga perlu diberikan informasi mengenai aturan minum obat yang tepat. Pemberian informasi melalui penyebaran brosur merupakan salah satu cara yang paling efektif untuk memperkenalkan aturan pemberian obat yang benar. Kegiatan tersebut berlokasi di Desa Buata, Kecamatan Botupingge, Kabupaten Bone Bolango. Hasil dari kegiatan ini, penderita diabetes melitus lebih siap menghadapi Ramadhan dengan aturan baru minum obat anti diabetes.
Edukasi dan Inovasi Keripik Bayam Sehat sebagai Alternatif Pangan Ibu Hamil Pencegah Anemia Nur Ain Thomas; Endah Nurrohwinta Djuwarno; Susanti Pakaya
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 3 (2022): Vol 1 Edisi 3 (2022)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (589.561 KB) | DOI: 10.3731/phar.soc.v1i3.18630

Abstract

Anemia   pada   ibu   hamil   berdampak   buruk   bagi   ibu   maupun   janin. Kemungkinan dampak buruk  terhadap ibu hamil yaitu proses persalinan yang membutuhkan waktu lama dan mengakibatkan perdarahan serta syok akibat kontraksi. Dampak buruk pada janin yaitu terjadinya    prematur, bayi lahir berat  badan rendah, kecacatan bahkan kematian bayi. Pengabdian ini bertujuan untuk  menghasilkan  produk  inovasi  yang  dapat  membantu  mengatasi  masalah anemia pada ibu hamil berupa pembuatan keripik bayam sehat. Pembuatan keripik bayam ini bertujuan untuk meningkatkan minat ibu hamil dalam mengkonsumsi sayuran yang kaya gizi dan dapat mencegah anemia disaat hamil. Kegiatan pengabdian kepada masyarakat ini bertujuan agar dapat mencegah kejadian anemia pada ibu hamil pada umumnya dan mencegah stunting pada anak pada khususnya. Pengabdian ini dilakukan dengan cara memberikan edukasi langsung mengenai pentingnya menghindari anemia disaat hamil pada ibu di saat posyandu ibu hamil dan membagikan keripik bayam sehat pada ibu hamil yang hadir. Pemberian edukasi dan pembagian keripik bayam pada masyarakat desa Bongohulawa khususnya ibu hamil mendapatkan respon yang baik karena sebagian besar masyarakat memiliki atensi yang tinggi melalui pertanyaan dan sangat menyukai produk olahan keripik bayam. Pengabdian ini memberikan manfaat yang besar bagi masyarakat desa agar mendapatkan pengetahuan mengenai manfaaat menghindari keadaan anemia disaat hamil dan memberikan informasi terkait produk olahan keripik bayam sehat.
Isolasi, Karakterisasi, dan Uji Antioksidan Fungi Endofit dari Tanaman Batang Kunyit (Curcuma domestica Val.,) Mahdalena Sy. Pakaya; Nur Ain Thomas; Hamsidar Hasan; Ariani H. Hutuba; Grasela Mbae
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.20341

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Endophytic fungi live in mutualistic symbiosis and can produce secondary metabolites similar to their host. This research aims to isolate, characterize, and test the antioxidant activity of secondary metabolites from turmeric stems. This research is experimental research where the method used for endophytic fungi isolation is the direct planting method, and antioxidant activity is tested using qualitative and quantitative methods with DPPH (1.1-diphenyl-2-picylhydrazyl). One fungal isolate was obtained with the fungal isolate code (BK). Based on macroscopic and microscopic characterization, the BK fungal isolate indicates the Deuteromycota class's characteristics. The qualitative antioxidant test results indicate that the fraction of BK endophytic fungal isolate indicates antioxidant activity, indicated by the yellow color against a purple background on the TLC plate observed under visible light. The respective ICso values for the ethyl acetate and n-hexane fractions were 52.989 µg/ml and 89.725 µg/ml, categorized as strong antioxidants. The methanol fraction had an ICso value of 119.02 µg/ml, categorized as moderate, while the pure supernatant fraction had an ICso value of 156.86 µg/ml, categorized as weak antioxidant activity.
Uji Penyembuhan Luka Bakar Gel Enzim Bromelin Menggunakan Carbopol 940 Secara In Vivo Nur Ain Thomas; Muhammad Taupik; Endah Nurrohwinta Djuwarno; Dizky Ramadani Putri Papeo; Nabila Novreini Djunaidi
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.20364

Abstract

Bromelain is a proteolytic enzyme or natural protease found in tissues, including the stem, fruit, and leaves of pineapple (Ananas comosus var. comosus) and other plant species of the Bromeliaceae family. Bromelain is known as an efficient debdriding agent because it is beneficial in  burn healing and tissue regeneration. This research aims to determine the effectiveness of bromelain enzyme for burns wounds in rabbits (Oryctolagus cuniculus). This research began with the optimization of carbopol 940 base preparations with variations in concentration, namely Formula 1 (F1) for 0,5%, Formula 2 (F2) for 1%, and Formula 3 (F3) for 1,5%. The evaluation of the gel formulation includes an organoleptic test, homogeneity test, pH test, viscosity test, adhesive force test, and spreadability test. The evaluation result indicates the base concentration in Formula 1 (F1) at 0,5% has met the requirements for a gel preparation. Formula 1 (F1) for 0,5, then combined with varying concentration of bromelain, namely Formula 1A (0,1%), Formula 1B (0,5%), and Formula 1C (1%). The gel formulation wa re-evaluated, including an organoleptic test, homogeneity test, pH test, viscosity test, adhesion test, spreadability test, irritation test, and in vivo test. In vivo effectiveness testing and irritation testing were conducted on five treatment groups, namely a positive control group (Bioplacenton®), Formula 1A (0,1%), Formula 1B (0,5%), Formula 1C (1%), and a group without treatment, then observed for 15 days. The observation data were processed using the One Way ANOVA test. Based on the results of the irritation test, Formula 1A (0,1%). Formula 1B (0,5%) and Formula 1C (1%) did not cause skin irritation. In the in vivo test, Formula 1C (1%) indicated the fastest recovery compared to other treatment groups, as evidenced by the decrease in wound diameter and visual observation, where the wound had started to close completely on day 15 of observation.
Pengaruh Konsentrasi Carbopol 940 Sebagai Gelling Agent Terhadap Stabilitas Fisik Sediaan Gel Lidah Buaya (Aloe Vera) Nur Ain Thomas; Robert Tungadi; Faramita Hiola; Multiani S. Latif
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.18050

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Carbopol 940 is a gelling agent that is very communly used in cosmetic production because of its high compatibility and stability, and it is non-toxic when applied to the skin and it spreads on the skin more easilym gels are semi solid preparations that contain a gel-forming agent which gives stiffiness to collodial solutions or dispersions used for external use on the skin, gel preparations are widely chosen because they are very easy to apply ( easily smeared, absorbed, and cleaned) and more attractive (transparent) compared to the other topical preparations. the purpose of this study was to determine the effect of carbopol concentration 940 as a gelling agent on the physical stability of aloe vera gel preparations. this study began with optimization of the carbopol 940 gel base then the preparation formulation used 50% aloe vera extract, 0,5% carbopol 940 F1, 1 % F2, 2% F3, 10 % propylene glycol, 10% glycerine, 0,1% dm dm hydantoin and sufficient aquadest, afterward the evaluation of the preparation included organoleptic, observations, homogeneity tests, pH tests, spreadability tests, adhesion tests and viscosity tests. carbopol 940 was depeloped using co-free water. gel preparations were 0,5%, 1%, and 2%. the results showed that the thrid formulation (F3) with a concentration of 2% fulfilled the physical evaluation requirements for organoleptic, spreadability, adhesion, viscosity, pH and homogeneity tests.
Pemberdayaan Masyarakat Pesisir Dalam Upaya Peningkatan Pengetahuan dan Keterampilan Memilih Obat Metode CBIA Menuju Masyarakat Pesisir Sehat Di Desa Monano Gorontalo Utara Hamsidar Hasan; Ekawaty Prasetya; Nurain Thomas; Julianti Akuba
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 2, No 3 (2023): Vol 2, Nomor 3 (2023)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v2i3.20875

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Visi Kementerian Kesehatan Republik Indonesia yaitu "Masyarakat Sehat yang Mandiri dan Berkeadilan" dengan salah satu misinya Meningkatkan derajat kesehatan masyarakat". Demi tercapainya maka perlu dilakukan perberdayaan masyarakat sehingga derajat kesehatan yang setinggi-tingginya bagi seluruh masyarakat Indonesia dapat tercapai. Kegiatan ini mempunyai tujuan untuk meningkatkan wawasan pengetahuan dan keterampilan masyarakat sehingga manpu menggunakan obat secara rasional untuk penggunaan sendiri dan di rumah tangga. Diharapkan setelah kegiatan ini masyarakat manpu mengetahui penggolongan obat, informasi kemasan dan etiket obat, cara memilih dan mendapatkan obat, bentuk sediaan obat, dois obat, cara penggunaan obat, efek samping obat, cara penyimpanan, kadaluarsa dan obat rusak, cara pembuangan obat, tata cara pelaksanaan metode CBIA. Kegiatan ini melibatkan mahasiswa KKS pengabdian yang sebelumnya telah dikader dan siap jadi tutor, pegawai puskesmas setempat dan penyelenggara dalam hal ini Dosen pembimbing lapangan yang telah di SK kan oleh LPM UNG. Metode pelaksanaan kegiatan adalah penyuluhan dan pelatihan bagaimana memilih obat dengan menggunakan alat bantu seperti paket obat, lembar kerja, dan petunjuk kegiatan. Kegiatan ini dilaksanakan selama 1 hari, jumlah peserta hadir 45 orang terdiri dari kelompok ibu-ibu nelayan, kelompok ibu-ibu PKK, Kelompok Karang Taruna, dan pemuka-pemuka Agama dan Masyarakat. Kegiatan ini memberikan manfaat bagi mereka yang sebelumnya tidak mengerti sama sekali tentang obat. Hasil evaluasi menunjukkan adanya peningkatan pengetahuan masyarakat setelah kegiatan ini.
Pengenalan Sejak Dini tentang Resistensi Antibiotik Kepada Mahasiswa Farmasi UNG dan Siswa SMK Farmasi di Kota Gorontalo melalui Program School of AMR PD IAI Gorontalo Mohamad Aprianto Paneo; Teti Sutriyati Tuloli; Nur Ain Thomas; Multiani S Latif; Muhammad Taupik; Endah Nurrohwinta Djuwarno
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 3, No 1 (2024): Vol 3. No. 1 (2024)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v3i1.25010

Abstract

Resistensi antibiotik telah menjadi perhatian utama dalam bidang kesehatan global karena dampaknya yang serius terhadap pengobatan infeksi bakteri. Fenomena ini terjadi ketika bakteri mengembangkan kemampuan untuk bertahan hidup dan berkembang biak meskipun terpapar antibiotik, mengurangi atau bahkan menghilangkan efektivitas obat tersebut. Penyebab utama resistensi antibiotik termasuk penggunaan antibiotik yang berlebihan, penggunaan yang tidak tepat, dan penyebaran gen resistensi melalui lingkungan. Konsekuensinya meliputi tingkat infeksi yang sulit diobati, peningkatan biaya perawatan kesehatan, dan peningkatan angka kematian. Upaya untuk mengatasi resistensi antibiotik melibatkan pendekatan multidisiplin termasuk penggunaan antibiotik yang bijaksana, pengembangan antibiotik baru, pengendalian infeksi, serta meningkatkan kesadaran masyarakat tentang masalah ini. Tujuan dilaksanakan kegiatan ini untuk memberikan edukasi sejak dini melalui program school of AMR Ikatan Apoteker Indonesia (IAI) kepada siswa dan mahasiswa bahwa pentingya mengenal antibiotik dan memutus rantai resistensi antibiotik. Kegiatan dilaksanakan dengan beberapa metode yang terdiri dari edukasi yang diberikan langsung oleh apoteker dan dosen, kemudian diskusi dan tanya jawab serta yang terakhir yaitu pemberian pre dan post kuesioner untuk melihat ketercapaian hasil dari kegiatan yang diberikan. Hasil menunjukan kenaikan yang progresif dari sebelumnya rata-rata pemahaman peserta berada dibawah nilai 80% menjadi rata-rata direntang 90%. Hal ini menunjukan pemberian edukasi secara terstruktur dan diberikan langsung oleh yang memiliki kompetensi akan memberikan dampak yang baik. Kegiatan seperti ini harus dilaksanakan secara berkelanjutan dengan harapan generasi berikutnya bebas dari penggunaan antibiotik yang tidak bijak.
Purchase Profile of Hypertension Drugs of Calcium Channel Blocker Group Amlodipine Doses of 5 mg and 10 mg in Several Gorontalo City Pharmacies January - March period in 2024 Paneo, Mohamad Aprianto; Thomas, Nurain Ain; Latif, Multiani S; Pido, Nur Huda
Jambura Nursing Journal Vol 6, No 2: July 2024
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jnj.v6i2.25339

Abstract

Hypertension is one of the most common diseases in Indonesia, one of which in the province of Gorontalo is included in the top 10 largest diseases. According to the health data profile from the Gorontalo provincial health office in 2022, the level of hypertension in Gorontalo city reached 2,325 cases, or around 4.6%. High cases of hypertension must be balanced with the provision of hypertension drugs, one of which is the calcium channel blocker (CCB) hypertension drug, amlodipine. The purpose of this study was to see the profile of purchasing hypertension drugs from the Calcium Channel Blocker (CCB) Amlodipine group in the community in Gorontalo City, especially in pharmacy and pharmaceutical service facilities. The research method uses a random sampling observation method, namely to see drug purchases in three Gorontalo city pharmacies located in different sub-districts. Purchase tracking was carried out in January, February, and March 2024. The results showed the purchase of amlodipine drugs in the three pharmacies in different amounts. Pharmacy B dominated the purchase of drugs compared to Pharmacy A and Pharmacy C at the 5 mg and 10 mg doses, respectively. Based on the results obtained, these differences are influenced by several indicators, including drug availability, drug completeness, pharmacy strategic location, and customer satisfaction.
Co-Authors A. Mu'thi Andy Suryadi A. Mu’thi Andy Suryadi Abas, Siti Nur Rahmatiya Abto, Nazarudin Adam Mustapa, Mohammad alkatiri, ahmad alkatiri Andi Makkulawu Anggai, Rifka Anggraini Anggun Sasmita Ibrahim Ariani H. Hutuba Arista Idris, Pinkan Bakari, Mohamad Fadly Bioto, Yakob Datu, Novanza L.M.N Defita Zubaidi Devie Ariany Daud Dr. Apt. Hamsidar Hasan S.Si.,M.Si Dwy Jayanto Palay, Rendy Ekaria Revalya Malopo Ekawaty Prasetya Endah Nurrohwinta Djuwarno Faradila Ratu Cindana Faradila Ratu Cindana Mo'o Fika Nuzul Ramadhani Fujiana Abd Karim Gita Potabuga Grasela Mbae Hamsidar Hamsidar Hamsidar Hasan Hamsidar Hasan Hamsidar Hasan Hiola, Faramita Ishak Isa Julianti Akuba Julianty Akuba Juniarista Jessica Pakaya LATIF, MULTIANI S Latif, Multiani S. Lisa Efriani Puluhulawa Lutfiah Pakaya Madania Madania, Madania Madania, Madania Mahdalena Sy Pakaya Mahdalena Sy Pakaya Makkulawu, Andi Maryadi Moh. Rivai Nakoe Mohamad Adam Mustapa Mohamad Aprianto Paneo Mohamad Reski Manno Mohi, Mega Agustiwi Muhamad Alpian Panu Muhammad Taupik Muhammad Taupik Multiani S Latif Multiani S Latif Multiani S. Latif Nabila Novreini Djunaidi Naharil Mumtazah Nakii, Siti Fatmawaty Nur Oktaviana Nur Rasdianah Oktaviani Kahar Pakaya, Nikmasari Papeo, Dizky Ramadani Putri Pido, Nur Huda Puluhulawa, Lisa Efriani Putri Febbiyanti Sabrina Rahmatia Is. Kaluku Rahmulia Thamrin Rakhmadana Fitraeni Basri Rismayani, Nur Robert Tungadi Robert Tungadi Robiatun Rambe Sapiun, Zulfiayu Selvi Marcellia Sidangoli, Adiva Sri Nur'ain E. Ahmad Suleman, Putri Rawe Sulistya Yasin Suryadi, A. Mu'thi Andy Suryadi, A. Mu’thi Andy Suryadi,, A. Mu'thi Andy Susanti Pakaya Teti Sutriyati Tuloli Timo, Nur Kharisma Ekaputri Tomu, Anita Faradiana Pratiwi R. Wanda Gita Van Gobel Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widysusanti A.K Windy Riani Suleman Wiwit Zuriati Uno Yayah Rachmatiyah Yelisnawati Harwanto Yuni Sarah Manoppo Zulmai Rani