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Scientific literacy on peatland across various study programs, genders, and current domicile of University Students in Borneo Sidauruk, Suandi; Ni'mah, Fatchiyatun; Meiliawati, Ruli; Analita, Rizki Nur; Rahmadani, Agung; Budi, Firman Shantya; Adhani, Aidhil
Journal of Education and Learning (EduLearn) Vol 19, No 1: February 2025
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/edulearn.v19i1.21794

Abstract

Scientific literacy is the ability that students must have to analyze and apply science concepts in solving everyday life problems. Students’ scientific literacy on peatlands can be acquired by students from daily interaction with peatlands, understanding that comes from parents and the community, as well as from learning in the classroom. This study aims to analyze the scientific literacy skills of students from several campuses in Borneo on the topic of peatlands. In this study, scientific literacy is described into scientific knowledge and scientific competencies domain. The research was conducted using a survey method with 528 respondents from several universities in Borneo, Indonesia. Research results show that even half of the respondents live around the peatland area, students’ scientific literacy is in the low category. The students’ scientific competencies need serious attention. A proper learning resources and comprehensive learning is needed to improve student overall scientific literacy.
Profil Kromatografi Senyawa Aktif Antioksidan dan Antibakteri Fraksi N-Heksana Daun Libo (Ficus variegata Blume) Rolan Rusli; Myra Puspha Hardina; Fairul Muflihah; Agung Rahmadani
Journal of Tropical Pharmacy and Chemistry Vol. 3 No. 2 (2015): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v3i2.98

Abstract

Research about chromatographic profile of antioxidant and antibacterial compounds in n-hexane fraction of Libo leaves (Ficus variegata Blume.) has been done in order to know the form of chromatographic profile of antioxidant and antibacterial compounds in n-hexane fraction of Libo leaves. Extraction was done by maceration using methanol. Isolation was done by 2 methods, vacuum liquid chromatography (VLC) then followed by conventional column chromatography. Eluent used are n-hexane-ethyl acetate and methanol-chloroform. The results based on conventional column chromatography are as many as 10 fractions. The fractions are being conducted then by a qualitative testing of the antioxidant activity using DPPH method and antibacterial activity test using bioautography TLC method. The results formed as a chromatographic profile of fraction that contain antioxidant and antibacterial activity, which are as many as 5 fractions (NHB1, NHB3, NHB4, NHC1, NHC3) active as an antioxidant and 4 fractions (NHB1, NHC1, NHC2, NHC3) which are active as an antibacterial. The secondary metabolite contents of the fractions are alkaloid, flavonoid and steroid/terpenoid.
Stirillakton Terasetilisasi dari Daun Tendani (Goniothalamus macrophyllus Hook.f. & Thoms) Asal Kalimantan Timur Agung Rahmadani
Journal of Tropical Pharmacy and Chemistry Vol. 3 No. 4 (2016): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v3i4.111

Abstract

Senyawa turunan stirillakton terasetilisasi telah berhasil diisolasi dari daun tendani (Goniothalamus macrophyllus Hook.f. & Thoms) asal Kalimantan Timur. Isolasi dimulai dengan maserasi menggunakan metanol, kemudian difraksinasi dengan n-heksana dan etil asetat. Ekstrak etil asetat diisolasi dengan teknik kromatografi kolom. Struktur isolat ditentukan strukturnya berdasarkan Spektroskopi Massa (MS), NMR (1D dan 2D). Struktur turunan stirillakton yang berhasil diisolasi diketahui sebagai 9-deoksigoniopipiron asetat. Kata Kunci: Daun tendani, goniothalamus macrophyllus, stirillakton, 9-deoksigoniopipiron asetat
Pharmaceutical Potential of 2’,4’-Dichloro-4-Hydroxy-3-Methoxychalcone Synthesized from Vaniline Eka Rizky Meilinda; Hajrah Hajrah; Agung Rahmadani; Laode Rijai
Journal of Tropical Pharmacy and Chemistry Vol. 4 No. 4 (2018): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v4i4.181

Abstract

Chalcone is an intermediate compound as the main precursor for the biosynthesis of flavonoid in plants. Chalcone has been known to have variety of different pharmacological activities. The difference in chalcone activity is influenced by the differences of subtituents found in both aromatic rings on the chalcone stucture. This study performed the synthesis of 2',4'-dichloro-4-hydroxy-3-methoxychalcone compound from the raw material of 2,4-dichloro acetophenone and vanillin by Claisen-Schmidt reaction using conventional method by stirring. The yield of synthesized compound is 91.57% of purity. The synthesized compounds were characterized by structural elucidation methods using IR, MS, 1H-NMR and 13C-NMR. Toxicity and antioxidant activity tests were performed on the synthesized compound. Base on the test results obtained LC50 value of 20.04 ppm and IC50 26.10 ppm. It is better to describe the pharmaceutical potential of 2',4'-dichloro-4-hydroxy-3-methoxychalcone little bit further.
Synthesis and Bioactivity of 3-(2,4-Dichlorophenyl)-5-(4-Hydroxy-3-Methoxyphenyl) Pyrazoline Nurul Khotimah; Agung Rahmadani; Dewi Rahmawati; Mirhansyah Ardana
Journal of Tropical Pharmacy and Chemistry Vol. 4 No. 4 (2018): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v4i4.183

Abstract

Pyrazoline is a five-ring heterocyclic compound having 3 carbon atoms and 2 nitrogen atoms known to have some biological activity. This study aims to synthesize 3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl) pyrazoline using 2’,4’-dichloro-4-hydroxy-3-methoxy chalcone and hydrazine. Synthesis was performed by reflux method at 80oC for 7 hours. The synthesis compounds were characterized by structural elucidation techniques. From the synthesis results obtained compound 3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl) Pyrazoline is pale yellow powder with 84%yield. The result of antioxidant activity test by 2,2-diphenyl-1-picrylhydrazyl (DPPH) showed that the compound had very strong antioxidant activity, Antibacterial test by diffusion method to use paper disk showed that the compound had antibacterial activity against Gram positive bacteria (S.aureus) and Gram negative bacteria (E.coli) and toxicity test by Brine Shrimp Lethality Test (BSLT) showed that the compound had toxicity.
Chemical constituents from Piper betle L. Var Nigra (Piperaceae) Fajar Prasetya; Supriatno Salam; Agung Rahmadani; Hadi Kuncoro; Rolan Rusli; Afif Ruchaemi; Sukartiningsih Sukartiningsih
Journal of Tropical Pharmacy and Chemistry Vol. 5 No. 3 (2021): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v5i3.322

Abstract

Two fatty acid derivatives, 2-octenoic acid and 2-hexenoic acid were isolated from the extract of n-hexane of the Piper betle L. Var. Nigra (Piperaceae). The chemical structures were identified on the basis of spectroscopic evidence and compared to previously reported spectra. These isolated compounds appear for the first time in the plant.
The Potency of the Genus Uncaria from East Borneo for Herbal Medicine Purposes: A Mini-review Maria Almeida; Supriatno Salam; Agung Rahmadani; Helmi Helmi; Angga Cipta Narsa; Sri Agung Fitri Kusuma; Sriwidodo Sriwidodo
Journal of Tropical Pharmacy and Chemistry Vol. 6 No. 2 (2022): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v6i2.457

Abstract

Uncaria is a genus of plants that are widely distributed in the tropics. There are about 5 of the 38 species of this genus growing in the tropical rain forests of East Borneo, Indonesia. For a long time, Uncaria is commonly used as a traditional medicine to treat various diseases by the Dayak tribe in Kalimantan, traditional people believe that Uncaria may be cured cancer, tumors, mioms, and cycts. Based on previous studies, the activity of the genus Uncaria has been widely reported such as cytotoxic, antimicrobial, antioxidant, antidiabetic, and thrombolytic activities. This article aims to summarize the potential of the Uncaria genus, focusing on 5 species from East Borneo, namely Uncaria nervosa, Uncaria longiflora, Uncaria gambir, Uncaria tomentosa and Uncaria cordata. The method used in this article is a literature study by collecting previous research articles related to the Uncaria genus. The results of the literature study show that the Uncaria genus in East Borneo has many secondary metabolites with diverse chemical structures that show good biological potential so that they can be used as broad and promising insights for drug discovery and development. This paper is also expected to provide input for the policy of conservation of medicinal plants in the forests of East Borneo.
Synthesis and Toxicity Tests of N-Carbothioamide-3-(2,4- Dichlorophenyl)-5-(4-Hydroxy-3-Methoxyphenyl)Pyrazoline Muhammad Irfan; Lisna Meylina; Agung Ramadhani; Rolan Rusli
Journal of Tropical Pharmacy and Chemistry Vol. 8 No. 1 (2024): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v8i1.612

Abstract

Pyrazoline is an alkaloid compound which has various biological activities such as antibacterial, antifungal, antitumor and anticancer. The compound N-carbotioamide-3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl)pyrazoline was successfully synthesized from the basic ingredients 2',4'-dichloro-4-hydroxy-3-methoxychalcone and thiosemicarbazide with sodium hydroxide catalyst at 80°C for 7 hours. The synthesized compound was characterized using 1H-NMR, 13C-NMR, and mass spectroscopy and had a yield of 28.03%. Based on the results of toxicity tests using the Brine Shrimp Lethality Test (BSLT) method, this compound has an LC50 value of 44.6 ppm and has the potential to be an antimicrobial compound.
Profil Kromatografi Senyawa Aktif Antioksidan dan Antibakteri Fraksi Etil Asetat Daun Libo (Ficus variegata Blume.) Mega Rizky Novitasari; Risna Agustina; Agung Rahmadani; Rolan Rusli
Jurnal Sains dan Kesehatan Vol. 1 No. 3 (2015): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i3.30

Abstract

Tumbuhan Libo (Ficus variegata Blume.) memiliki buah yang tidak dimakan oleh hama/serangga, hal ini diduga karena kandungan metabolit sekunder tumbuhan libo mengandung senyawa aktif yang dapat berpotensi sebagai antibakteri maupun antioksidan. Penelitian ini bertujuan untuk mengetahui profil kromatografi senyawa antioksidan dan antibakteri, serta mengetahui golongan metabolit sekunder yang terdapat dalam fraksi aktif etil asetat daun libo. Sampel dimaserasi dengan pelarut metanol. Isolasi dilakukan sebanyak 2 kali yaitu dengan cara kromatografi cair vakum kemudian dilanjutkan dengan kromatografi kolom konvensional. Hasil pemisahan berdasarkan kromatografi kolom konvensional yaitu diperoleh sebanyak 16 fraksi. Dari hasil tersebut kemudian dilakukan pengujian aktivitas antioksidan terhadap DPPH dan pengujian aktivitas antibakteri terhadap bakteri uji dengan metode KLT Bioautografi. Hasil penelitian diperoleh profil kromatografi fraksi etil asetat daun Libo (Ficus variegata Blume.) aktif sebagai antioksidan terhadap DPPH, dan aktif terhadap bakteri, Eschericia coli dan Staphylococcusaureus. Golongan metabolit sekunder aktif fraksi etil asetat daun libo adalah alkaloid, steroid, terpenoid dan fenol.
Analisis GC-MS Senyawa Aktif Antioksidan Fraksi Etil Asetat Daun Libo (Ficus variegata Blume.) Mega Rizky Novitasari; Lizma Febrina; Risna Agustina; Agung Rahmadani; Rolan Rusli
Jurnal Sains dan Kesehatan Vol. 1 No. 5 (2016): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i5.43

Abstract

Daun Libo (Ficus variegata Blume.) memiliki daun yang tidak dimakan oleh hama/serangga, hal ini diduga karena kandungan metabolit sekunder daun libo mengandung senyawa aktif yang potensial salah satunya adalah sebagai antioksidan. Penelitian ini dilakukan untuk mengetahui komponen senyawa antioksidan fraksi etil asetat daun libo dengan metode GC-MS. Interpretasi spektrum massa GC-MS dilakukan dengan menggunakan database WILLEY9THN 08.L. Hasil analisis spektrum GC-MS fraksi etil asetat aktif antioksidan mengandung 2,5-Cyclohexadiene-1,4-dione, 2,6-bis(1,1-dimethylethyl (0,65%), 1-Octadecene (1,29%), 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- (1,54%), 7,9-Di-tert-butyl-1-oxaspiro(4,5)deca-6,9-diene-2,8-dione (1,52%), 1-Nonadecene (3,39%), 1-Docosene (3,39%), Nonadecyltrifluoroacetate (2,12%), 1,2-Benzenedicarboxylic acid,(2-ethylhexyl) ester (45,53%), 1-Docosene (2,71%), Pyrene, hexadecahydro (4,56%), Urs-12-en-3-ol, acetate,(3.beta.) (1,97%), 12-Oleanen-3-yl acetate, (3.alpha.)- (5,19%), Urs-12-en-3-ol, acetate,(3.beta.) (1,53 %), Taraxasterol-acetate (0,30%), 1-(Dimethylamino)-5-{[4'-(5"-(4"'-iodophenyl ethynyl|)-1"-naphthylethynyl]-1(8,46%), dan 7,8,17,18-Tetrahydro-35-methoxy-1,3,21,23-tetramethyl-16H,31H-5,9,15,19-dime (10,04%).
Co-Authors Abdul Aziz Adam M. Ramadhan Adam M. Ramadhan Adhani, Aidhil Aditya Fridayanti Afif Ruchaemi Ahmed Jhordy Almeida, Maria Amanuddin Amanuddin Angga Cipta Narsa Anggraeni, Egi Syahrah Arief Fadillah Arifian, Hanggara Arjuna Pramana Asiyah, Mely Nor Ata, Putri Fritami Atin Nuryadin Atria Kent Awaliyah, Nabilah Nailah Bayu Heris Apriyanto Bela Apriliana Ningsih Cahayani, Mega Cahyo, Risky Nor Debbi Pasedan Dewi Noorjannah Utami DEWI RAHMAWATI Dewi Rahmawati Dewi Rahmawati Diana Kurnia Apriani Diana Ntowe Didi Fadilla Eka Rizky Meilinda Elisa Yunita Emma Susilowati Shabir Enggar Wijayanti Erlin Dwi Nurrohimi Erwin Erwin Fairul Muflihah Fajar Prasetya Fajar Prasetya Farah Erika Farah Erika Farah Erika Fika Aryati Firman Shantya Budi, Firman Shantya Firnanda Zuni Fransiska Ganjar Firmansyah Hadi Kuncoro Hadi Nur Hajrah Hajrah Hajrah Hajrah Hanggara Arifian Hanggara Arifian Harra Ismi Farah Hartandi, Dimas Hasan, Hafia Hazlina, Nur Helmi Helmi Herman Herman Hilalliyah, Nur Husnul Khatimah Indah Silvia Sugiyamin Indriana Tasya Indriana Tasya Islami, Agustina Amalia Isyra, Klara Wahyu Jaka Fadraersada Jeremia Giawa, Agusto Kadir, Nurdianah Abdul Kama Tasawa, Gymnastiyar Laode Rijai Laode Rijai Laode Rijai Laras Indah Wulandari Larasati, Herlin Alfiana Lestari Lestari Lisna Meylina Lisna Meylina Lita Yulianti Lizma Febrina Lizma Febrina M Arifuddin M. Ari Prayogo Masruhim, Muh. Amir Maulina, Tiara Mega Cahayani Mega Rizky Novitasari Meiliawati, Ruli Mirhansyah Ardana Mitha Saputri Muhammad Ansar Muhammad Choirul Muhammad Irfan Muhammad Ridwansyah Muhammad, Ridwansyah Mukhamad Nurhadi, Mukhamad Myra Puspha Hardina Myra Puspha Hardina Ni'mah, Fatchiyatun Nisa Naspiah Nova Yunita Putri Olii Nur Awaliah Nur Masyithah Zamruddin Nur Shidiq Nurdianah Abdul Kadir Nursilawati, Nursilawati Nurul Fitriyah Sulaeman, Nurul Fitriyah Nurul Khotimah Olii, Nova Yunita Putri Pakaenoni, Frederich Palapa, Kaleb Gideon Pandiangan, Masda Prastika, Nanda Diah Purwita Sari, Regina Putri Fritami Ata Putri, Rizka Amalia Rachma Nadya Utami Rahman, Karisa Apriyani Rahman, Zainur Arif Ramadani, Pino Rengganis, Ajeng Ayu RISKA OKTAVIANI Risna Agustina Rizki Nur Analita Rolan Rusli Romisa, Fahmi Sarifah, Awalus Siburian, Putri Dela Silalahi, Yoisi Fortuna Simangunsong, Ari Putra Wijaya Sin Yuan Lai Sinaga, Hilga Natasya Sri Agung Fitri Kusuma Sri Lestari Sri Lestari Sri Wulandari Sriwidodo Sriwidodo Suandi Sidauruk Sukartiningsih Sukartiningsih Sukemi Sukemi Sukemi Sukemi sukmawati Supriatno Salam Supriatno Salam Susanti, Revi Syahputri, Salsabila Dia Tasya, Indriana Teguh Wirawan Tiara Maharani, Tiara Tri Woro Widyanti Tristania, Auriel Wafiq Turista, Dora Dayu Rahma Usman Usman Usman Usman VICTORIA YULITA FITRIANI Vina Maulidya Vina Maulidya Viriyanata Wijaya Wahyu Yunita Lestari Watulingas, Maasje Catherine Wirhanuddin, Wirhanuddin Yulian, Satifa Ananda Yulianti, Ayu Dwi Yuniar Ponco Prananto Yurika Sastyarina Yuspian Nur Zhiying Zhu