Anemia among adolescent girls remains a major public health concern in developing countries, including Indonesia. This condition is related to increased iron requirements during growth, menstrual blood loss, inadequate dietary intake, low health literacy, and limited family support in maintaining behaviors. This study aims to analyze the role of digital-based family counseling models in improving knowledge and promoting anemia prevention behaviors among junior high school adolescent girls. A qualitative descriptive literature review was conducted by systematically searching relevant articles published between 2020 and 2025 in Google Scholar, Scopus, PubMed, and SINTA-indexed journals using predefined inclusion and exclusion criteria. Selected studies were analyzed thematically to identify patterns related to digital health education, family involvement, and integrated intervention outcomes. The findings indicate that anemia prevalence among adolescent girls remains high in rural areas, and is influenced by dietary patterns, low adherence to iron supplementation, awareness, and insufficient supervision. Digital-based health education interventions significantly improve adolescents’ knowledge and attitudes compared to conventional approaches. Furthermore, integrating digital media with structured family counseling strengthens parental engagement, enhances access to health information, and supports sustainable behavioral change. Therefore, digital-based family counseling is recommended as an integrated strategy to improve adolescent health literacy and reduce anemia risk.