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Edukasi Pencegahan Stroke pada Masyarakat Desa Cigugur Girang: Stroke Prevention Education in Cigugur Girang Village Goenawan, Hanna; Tarawan, Vita Murniati; Radhiyanti, Putri Teesa; Ramadhanti, Julia; Lesmana, Ronny
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 8 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i8.7058

Abstract

Stroke patients could get sequelae, and it will decrease the patient’s quality of life. Stroke could be caused by comorbid diseases such as hypertension, diabetes mellitus, and dyslipidemia. Thus, stroke could be prevented by reducing the comorbid diseases. The prevention of stroke is necessary to be done in order to reduce stroke cases, especially in Bandung’s rural area. Villagers have limited access to health information and health services. In this community service, the methods we used were to screen the two risk factors of stroke (blood pressure and blood glucose ad random measurement) in Cigugur Girang Village, West Bandung area. The aim of this community service is to find comorbid factors of stroke and give education to people who have one or more stroke risk factors. The results of the blood pressure measurement screening showed that more than 40% of the residents of Cigugur Girang village had blood pressure above normal, and 5% of the population had blood sugar levels higher than normal. The risk factor for stroke in residents of Cigugur Girang Village mainly is high blood pressure. In this community service, people with high blood pressure were educated on how to maintain normal blood pressure and how to change their lifestyle. On the other hand, some participant has high blood glucose level. High blood glucose levels will develop into diabetes mellitus. In this education program, we gave information about the complications of high blood glucose, including stroke. Thus, this education program could increase community awareness to prevent stroke.
Hatha Yoga vs Prenatal gymnastic: The Perfect Choice to Reduce Stress and Improve Health for Primigravid Fernandez, Veronica; Lesmana, Ronny; Krisnadi, Sofie Riyani; Susiarno, Hadi; Tarawan, Vita Murniati; Iskandar, Shelly
JURNAL KEBIDANAN Vol. 15 No. 1 (2025): April 2025
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v15i1.12677

Abstract

Abstract: Pregnancy is a critical period involving significant physiological and psychological changes, particularly in primigravida women who are more susceptible to anxiety and stress. Elevated stress levels during pregnancy may increase the risk of complications like high blood pressure, preeclampsia, and premature delivery. Non-pharmacological interventions like Hatha Yoga and gymnastic prenatalhave been widely recommended to improve maternal well-being. The purpose of this research was to evaluate and compare the impacts of two different interventions on maternal psychological and physiological health through a Systematic Literature Review (SLR) conducted in accordance with PRISMA guidelines. Relevant literature was retrieved from databases including Pubmed, Scopus, ScinceDirect, Google Scholar, focusing on research published between 2014 and 2024. The findings indicate that Hatha Yoga is more effective in reducing anxiety, cortisol levels, and systolic blood pressure, while prenatal gymnastic better supported diastolic blood pressure regulation and physical endurance for labor. Both interventions contribute to better cardiovascular function, increased oxygen saturation, and a smoother labor process. Additionally, yoga is associated with improved neonatal outcomes, while studies on prenatal exercise’s effects on newborn health remain limited. Future research should explore the long-term effects and key differences between these interventions to determine the most effective approach for maternal and neonatal health. These findings support integrating yoga and gymnastic prenatalinto antenatal care programs to enhance pregnancy outcomes.
The Comparative Effects of Hatha Yoga and Prenatal Exercise on Physiological and Psychological Outcomes in Primigravid Women: A Randomized Controlled Trial Fernandez, Veronica; Lesmana, Ronny; Krisnadi, Sofie R.; Susiarno, Hadi; Iskandar, Shelly; Tarawan, Vita Muniarti
Journal of Applied Nursing and Health Vol. 7 No. 3 (2025): Journal of Applied Nursing and Health
Publisher : Chakra Brahmanda Lentera Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55018/janh.v7i3.445

Abstract

Background: Primigravid women are prone to stress due to physical and psychological changes during pregnancy, which can lead to hypertension, preeclampsia, preterm birth, fetal growth restriction, and postpartum depression. While non-pharmacological interventions like hatha yoga and prenatal exercise are used to reduce stress, comparative evidence—especially on oxygen saturation (SpO₂)—is limited. This study analyzes the effects of hatha yoga and prenatal exercise on stress, blood pressure, and SpO₂ among primigravid women, and compares both interventions across these outcomes. Methods: This randomized controlled trial (RCT) followed the CONSORT 2010 guidelines. Forty-eight eligible primigravid women were selected using a probability sampling technique, specifically the simple random sampling method. Random numbers were generated using Microsoft Excel to determine participant selection from the maternal cohort register. Inclusion criteria were a normal singleton pregnancy at 24–28 weeks of gestation, maternal age 20–35 years, and normal Body Mass Index (BMI) (18.5–24.9 kg/m²). Exclusion criteria included regular exercise more than twice a week, abnormal fetal heart rate, and scheduled elective cesarean delivery. Participants were randomly assigned to either a hatha yoga group or a prenatal exercise group (24 each). Both interventions were conducted twice weekly for four weeks. Data were analyzed using the Wilcoxon and Mann–Whitney tests. Results: Data were analyzed using the Wilcoxon and Mann-Whitney tests. Median stress scores decreased from 22 to 12 in the hatha yoga group and from 22 to 17 in the prenatal exercise group (p < 0.001). Median SpO₂ increased from 96.88% to 98.38% and from 96.81% to 97.00%, respectively (p = 0.002). Median systolic pressure changed from 120.06 to 121.31 mmHg and 118.75 to 117.44 mmHg (p = 0.009), while diastolic pressure showed no significant difference (p = 0.076). Overall, hatha yoga showed greater improvements in stress, SpO₂, and blood pressure stability than prenatal exercise. Conclusion: Hatha yoga proved more effective than prenatal exercise in reducing stress, increasing SpO2, and stabilizing systolic blood pressure among primigravid women, although no significant difference was found in diastolic pressure. These findings strengthen the evidence supporting yoga as a safe, non-pharmacological approach to enhance maternal physiological and psychological well-being during pregnancy.
The Phenolic Compounds Isolated from Myristica fragrans and Their Cytotoxic Effects on B16-F10 Melanoma Cancer Cell Lines Hasbilla, Raihan Fathurrahman; Riyadi, Sandra Amalia; Safriansyah, Wahyu; Hidayat, Ace Tatang; Susianti, Susianti; Salam, Supriyanto; Lesmana, Ronny; Retnowati, Rurini; Supratman, Unang
Molekul Vol 20 No 3 (2025)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2025.20.3.16265

Abstract

Phenolic compounds are a major type of secondary metabolite found in plants. These compounds are synthesized through shikimic and phenylpropanoid pathways, resulting in the formation of numerous unique structures and bioactivities. In addition, a significant amount has been reported in nutmeg, an endemic plant of Indonesia, which has been widely used in traditional medicine. A previous study also revealed that ethyl acetate extract of the plant has notable cytotoxic effects against melanoma B16-F10. Therefore, the purpose of this study is to isolate and evaluate phenolic compounds in nutmeg for their potential to inhibit B16-F10 melanoma cancer cell growth. The seeds extract of nutmeg was separated by various chromatographic techniques to yield a total of five compounds, which were identified through spectroscopic analysis (HR-TOF-ESI-MS, IR, and NMR) as well as comparison with literature. The compounds 1-5 were identified as (+)-veraguensin (1), 3',4',5'-trimethoxycinnamyl alcohol (2), (+)-galbegin (3), (-)-polysphorin (4), and 7-methoxycoumarin (5). Cytotoxic effects were then assayed against B16-F10 melanoma cell lines using the Resazurin method. Furthermore, compound 1 displayed the highest cytotoxic activity, with an IC50 value of 112.71 µM.
The AKT Pathway and Satellite Cell Activation in Skeletal Muscle Mass Regulation Sofiyanti, Santi; Goenawan, Hanna; Lesmana, Ronny; Tarawan, Vita Murniati
Folia Medica Indonesiana Vol. 58, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlight: • AKT or protein kinase B increase protein synthesis and control the degradation of proteins. • Satellite cells was provided remarkable ability to regenerate skeletal muscle. • Stimulation of protein synthesis is effective therapy to maintain muscle mass, prevent muscle wasting to reduce risk sarcopenia and improve quality of life in the elderly. Abstract: Muscles have an important role as a regulator of glucose and triglyceride metabolism. Some researches show the correlation between skeletal muscle mass and metabolic diseases, such as diabetes. Skeletal muscle mass decrease occurs due to chronic illness or physiological process of aging, thus increasing the risk of metabolic diseases as well as motion difficulty in the elderly. Skeletal muscle mass depends on balanced protein synthesis and degradation, controlled through a variety of signal transduction pathways including the AKT. AKT or protein kinase B increases protein synthesis through the mTOR and GSK3β and controls the degradation of proteins through FoxO transcription factors. Another factor that has an alleged role in the regulation of skeletal muscle is the satellite cells which provide remarkable ability to regenerate skeletal muscle. A comprehensive understanding of the biomolecular mechanism of muscle mass regulation is important to develop effective treatment or prevention of muscle atrophy in many cases, either caused by pathological conditions, such as chronic diseases, or the process of aging.
Pengaruh Tablet Fe dan Kombinasi Tablet Fe dengan Yoga Pada Remaja Putri yang Mengalami Anemia dengan Dismenore Aisya Astri Yunas; Hanom Husni Syam; Vita M.T.; Ruswana Anwar; Meita Dhamayanti; Ronny Lesmana
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.49481

Abstract

Dysmenorrhea and anemia are common health problems among adolescent girls, while pharmacological therapy has limitations, highlighting the need for safe and comprehensive alternative interventions. This study aimed to analyze the effects of Fe supplementation and the combination of Fe supplementation with yoga on hemoglobin levels and dysmenorrhea intensity in adolescent girls. A quasi-experimental design with a two-group pre-test post-test approach was employed. Participants were adolescent girls from SMAN 03 Rejang Lebong who received either Fe supplementation or a combination of Fe supplementation and yoga for four weeks. Data were analyzed using the Wilcoxon and Mann-Whitney tests. The results showed that the combination of Fe supplementation and yoga significantly improved hemoglobin levels and reduced dysmenorrhea intensity (p = 0.000). Moreover, the combination was more effective than Fe supplementation alone. These findings suggest that combining yoga with Fe supplementation can serve as an effective non-pharmacological strategy to manage anemia and dysmenorrhea among adolescent girls. Keywords: dysmenorrhea, anemia, Fe supplementation, yoga, adolescent girls
Penggunaan Asam Hipoklorit secara Topikal Mempercepat Fase Inflamasi dan Proliferasi Penyembuhan Luka Infeksi Kulit Kucing Skabies Parmadhi, Anindya Putri Parmadhi; Lesmana, Ronny; Rosdianto, Aziiz Mardanarian
Jurnal Veteriner Vol. 26 No. 4 (2025)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/

Abstract

Skabies merupakan salah satu infeksi kulit yang sering dijumpai pada kucing yang mana disebabkan oleh tungau Sarcoptes scabiei ataupun Notoedres cati. Gejala penyakit ini termasuk rasa gatal (pruritus) yang menyebabkan aktifitas menggaruk secara berlebih dan adanya penebalan kulit. Jika tidak ditangani, pertumbuhan tungau akan tidak terkontrol dan dapat menyebabkan imunosupresi. Ivermectin 1% merupakan obat yang umum digunakan untuk menangani penyakit ini. Disamping itu, hypochlorous acid (HOCl) 0,01% yang telah distabilkan terbukti memiliki efek antiinflamasi, anti-pruritus. Penelitian ini bertujuan untuk melihat gambaran HOCl terhadap infeksi kulit skabies pada kucing. Penelitian ini menggunakan 3 kucing yang dibagi menjadi 3 perlakuan, yaitu kontrol negatif (tidak diberi perlakuan), kontrol positif (pemberian ivermectin 1% 0,05 mL/kgBB secara subkutan), dan perlakuan HOCl 0,01% (pH 5,5-6,5) yang berdurasi selama 7 hari. Pengamatan secara makroskopis dilihat dari adanya eritema, pinnal-pedal reflex, alopecia, hiperkeratosis, pus, warna, dan bentuk permukaan lesi. Dokumentasi dilakukan dengan menggunakan penanda 2x2 cm untuk perbandingan ukuran lesi. Hasil yang didapatkan, HOCl terbukti mengurangi hiperkeratosis dan mempercepat penyembuhan luka akibat garukan. Perbandingan waktu kesembuhan antara kontrol positif dan perlakuan teramati sama, yaitu dimulai pada hari ke-3. Asam hipoklorit (HOCl) secara topikal dapat membantu mempercepat fase inflamasi dan proliferasi penyembuhan luka.
Performance determinants in tropical trail running: Race result analysis of the 5K and 10K Merapi Merbabu de Trail 2025 Siti Baitul Mukarromah; Sugiarto Sugiarto; Gustiana Mega Anggita; Sri Agus Budi Santoso; Sangheon Park; Ambar Dwi Erawati; Rikha Liemiyah; Aziiz Mardanarian Rosdianto; Ronny Lesmana; Faisyal Syofian
Physical Education and Sports: Studies and Research Vol. 5 No. 1 (2026): Physical Education and Sports: Studies and Research
Publisher : CV Rezki Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56003/pessr.v5i1.699

Abstract

Background: The limited research on the determinants of performance in short-distance trail running in tropical environments is a major problem in understanding the influence of environmental conditions on runners' performance and pacing strategies.Objectives: This study aimed to examine the influence of race distance, sex, and age on trail running performance in the 5K and 10K categories of the Merapi Merbabu de Trail 2025.Methods: A retrospective observational race result analysis was conducted using official race data from the Merapi Merbabu de Trail 2025. The study included 429 runners (5K: n = 144; 10K: n = 285), consisting of 275 male and 154 female participants. The primary outcome variable was finish time (in minutes), while the independent variables included race, distance, sex, and age. Statistical analyses were performed using SPSS version 26, including descriptive statistics, independent-samples t-tests, Cohen’s d effect sizes, and multiple linear regression to evaluate predictors of performance.Results: Results showed a significant difference in performance between race distances. The mean finish time for the 5K category was 152.8 ± 44.3 minutes, while the 10K category averaged 306.1 ± 74.3 minutes (t = -26.68, p < 0.001, Cohen’s d = 2.50). Male runners completed the 10K race faster than female runners (293 vs. 345 minutes). Regression analysis indicated that finish time increased by approximately 2–3 minutes per year of age, indicating a progressive decline in performance with increasing age.Conclusions: These findings indicate that race distance, sex, and age are significant determinants of trail running performance in tropical environments.
Co-Authors . SETIAWAN . Susianti Abd. Rasyid Syamsuri Abdul Hadi Hassan Ace Tatang Hidayat Achadiyani Agus Muji Santoso Agus Syahrani Agus Syahrani Ahmad Kurniawan Ahmad Kurniawan Ahmad Ramdan Aisya Astri Yunas Ajeng Diantini Aldo Hartono Aldo, Mochammad Alia Bihrajihant Raya Alia Bihrajihant Raya Ambar Dwi Erawati Ambrosius Purba Ambrosius Purba Anang Wahid M.Diah Anas Subarnas Anas Subarnas Andrew Citrawan Anggraeni Dyah S Anggraeni Dyah Sulistiowati Anissa Anissa Anissa, Anissa Annisa F. Dewi Arief Budiono Arief Cahyanto Arief S. Kartasasmita Arifin Dwi Saputro Arto Yuwono Soeroto Astrid Feinisa Khairani Astrid, Stephanie Aulina, Datin Zahira Aziis Mardanarian Rosdianto Aziiz Mardanarian Rosdianto Aziiz Mardanarian Rosdianto Aziiz Mardanarian Rosdianto Aziiz Rosdianto Azis Mardanarian Azmi, Mohamad Nurul Bachtiar, Willy Bahjah, Firda Hanan Baniasih, Akbar I. Baniasih, Akbar I. Bashari, Muhammad H. Bela Ita Karina Daba, Mariel Dani Sujana Darmayanti, Meita Decky Gunawan, Decky Dewi, Annisa F. Diana K Jasaputra Diana Krisanti Jasaputra Diana Krisanti Jasaputra Diandra Syifa Dimpuulina Erna Mariati Dwi Putri Larasati Edi Sukmana Edi Sukmana Edward J Hadi Endang Sutedja Endang Sutedja Enny Rohmawaty Euis Julaeha Evi Rinata Faisyal Syofian Fajar Ari Widyatmoko Fani Rahma Yenita Fathurachman Fathurachman Fatona Suraya, Fatona Febriana Kurniasari Ferdyan Efza Fernandez, Veronica Fifi Veronica Filza Yulina Ade Finda Meyditia Finda Meyditia Fitri Fadhilah Galuga Sinalusur Sari Genta Syaifrin Laudza Gilang Muhamad Nur Iqbal Goenadi, Julia Windi Gunadi, Julia Windi Gunawan, Hanna Gustiana Mega Anggita Hadi Hadi Hana Goenawan Hanna Goeanawan Hanna Goenawan Hanna Goenawan Hanna Goenawan Hanna Gunawan Hanom Husni Syam Hasbilla, Raihan Fathurrahman Hendra Gunawan Hendy Setiawan Hendy Setiawan Herlina, Lien Herry Herman Hilmi Al Wahid Huda, Fathul Huda, Fathul I Made Joni Ida Ayu Putu Sri Widnyani Ieva B. Akbar Ieva Baniasih Akbar Ika M. Silviana Imam Megantara Indahwati, Dwiwahju Dian Irma Erika Herawati Irma Erika Herawati Irma Melyani Puspitasari Irma Ruslina Defi Isa Mahendra Ivan Christian Channel Ivanna Valentina Iwan Setiawan Iwan Setiawan Iwan Setiawan Iwan Setiawan Jatnika, Danti Dja Jihan Mudrika Rahmi Julia W Gunadi Julia Windi Gunadi Julia Windi Gunadi Jutti Levita Kanakarajah, Sarmmila Kartika Hajar Kirana Kastella, Faysal Keiichi Motoyama Khairinisa, Miski A. Krisnadi, Sofie Riyani Kusmawan, Steven Zerin Putra Lazuardhi Dwipa Leonardo Lubis Madhani Pradiptha Nugroho Maharani, Julia Maimun Syukri, Maimun Mariel Daba Mas Rizky A.A. Syamsunarno MEGANTARA, SANDRA Meita Dhamayanti Muchtaridi Muchtaridi Mulyanaga, William Giovanni Mutakin Mutakin Mutiarahmi, Citra Nur Nabilah Muhamad Naini, Al Arofatus Nanang Wahyudin Nanang Wahyudin Nanny N. N. M. Soetedjo Nasrul Wathoni Norisca Aliza Putri Nova Sylviana Nova Sylviana Nuraini Yasmin Nuroh Najmi Nurul Fadhilah Oki Suwarsa Okta Wismandanu Oktorina, Lenny Pangestuti, Balqist Sriprobo Pardede, Akim Manaor Hara Parmadhi, Anindya Putri Parmadhi Penny Setyawati Martioso Permadi, Andieni Faqhira Permana, Noah Jefferson Permana, Shenny S.S Pinkan Al Shabrina Pitu Wulandari Prasetyo, Wibowo Budi Prayudi Santoso Putri Tessa Putri, Aufa A.D Qiantori, Adziqa Ammara Radhiyanti, Putri Teesa Rahdiyanti, Putri Teesa Ramadhanti, Julia Ramdani Hamzah Ray, Hamidie Ronald Daniel Rejeki, Purwo Sri Renaldi Prasetia Reni Farenia Reni Farenia Rikha Liemiyah rima siburian Riska A Safira Risna Agustina Risna Agustina Roro Wahyudianingsih Rosdianto, Aziis Mardanarian Rosdianto, Aziiz M. Rosdianto, Aziiz Mardanarian Rurini Retnowati Rusdin, Agus Ruswana Anwar Safriansyah, Wahyu Salam, Supriyanto Sandra Amalia Riyadi Sangheon Park Sarmmila Kanakarajah Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Setiawan Shelly Iskandar Silviana, Ika M. Simanungkalit, Jayne Mary Siti Baitul Mukarromah Siti Mukarromah Siti Nuriyatus Zahrah Slamet Imron Sofie R. Krisnadi Sofiyanti, Santi Sri Adi Sumiwi Sri Agus Budi Santoso Steffi Liem Sudigdo Adi Sudrajat, Ratu Z.A.P sugianli, Adhi Sugiarto Sugiarto Sukmayani, Jasmine Y. Sunarjati Soedigdoadi Sunarjati Sudigdo Adi Sunarjati Sudigdo Adi Sunarjati Sudigdoadi Sunaryati S. Adi Supriatno Salam Susanti Husen Susianti Susianti Susianti Susianti Susianti, Susianti Susiarno, Hadi Tarawan, Vita M. Tarawan, Vita M. Teresa Lucretia, Teresa Teti Madiadipoera TIANA MILANDA Tina Rostinawati Titing Nurhayati Tjahjono D. Gondhowiardjo Tri Mayanti Trianing Tyas Kusuma Tyagita Hartady Unang Supratman Vita M. Tarawan Vita M.T. Vita Muniarti Tarawan Vita Murniati Tarawan Vita Murniati Tarawan Vita Murniati Tarawan Lubis Vita Mutia Tarawan Wahyudianigsih, Roro Wahyuni, Indah S. Willy Bachtiar Yanuar Dwi Prastyo Yasmin, Nuraini Yenny Noor Yudi Feriandi Yulia Sofiatin Yumilia, Hoo Yuni Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi Yuni Susanti Pratiwi, Yuni Susanti Yusuf, Muchamad R.A Zaini, Lia M. Zakiyah, Neily Zulhendri, Felix