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Journal : Narra J

Physical exercise and chicken egg white supplementation increase muscle mass of stable COPD patients Amin, Mona N.; Tarigan, Amira P.; Pradana, Andika; Ashar, Taufik; Osareniro, Osakue E.
Narra J Vol. 4 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i1.406

Abstract

Patients with chronic obstructive pulmonary disease (COPD) commonly exhibit muscle atrophy and dysfunction due to a reduction in muscle mass; and protein supplements such as chicken egg whites have been reported to improve muscle mass. The aim of this study was to evaluate the impact of physical exercise and egg white supplementation on the muscle mass of COPD patients. An experimental study was conducted among stable COPD patients at Universitas Sumatra Utara Hospital Medan, Indonesia, between August and October 2022. The patients were divided into two groups, control and interventional groups, with each patient subjected to a pre- and post-muscle mass assessment. All the patients performed respiratory endurance and upper extremity muscle strength training three times/week for a total of 12 weeks. In addition, the patients in the intervention group were also given egg white supplementation (10 eggs/day) during the period of intervention in addition to the physical training. The Wilcoxon and Mann-Whitney tests were performed to identify the significance of the difference between pre- and post-intervention and between the control and intervention groups, respectively. A total of 38 COPD patients were included in the study, 19 from each group. Our data suggested no significant difference in muscle mass of the patients in the control group before and after 12 weeks of physical exercise (pre-intervention 27.37±4.54% and post-intervention 27.68±4.5% with p=0.174). However, there was a significant muscle mass increment of patients in the intervention group upon 12 weeks of physical training and egg white supplementation (pre-intervention 27.18±4.15%, post-intervention 29.95±3.76%, p<0.001). A significant difference in muscle mass was observed between patients in the control and the intervention groups (p=0.046) after the intervention. The study highlights that physical exercise in combination with egg white supplementation may serve as potential and effective non-pharmacological treatment for muscle mass restoration in COPD patients as compared to physical exercise alone.
Profile and risk factors of pre-XDR-TB and XDR-TB patients in a national reference hospital for Sumatra region of Indonesia Sinulingga, Herison E.; Sinaga, Bintang YM.; Siagian, Parluhutan; Ashar, Taufik
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.407

Abstract

The low treatment rate, low treatment success rate and high mortality rate of patients with pre-extensively drug-resistant tuberculosis (pre-XDR-TB) and extensively drug-resistant TB (XDR-TB) need serious attention. The aim of this study was to describe the profiles of patients with pre-XDR-TB and XDR-TB cases and to determine associated risk factors of their incidence in Indonesia. A retrospective case-control study was conducted at H. Adam Malik General Hospital in Medan, North Sumatra of which all sensitive-drug TB (SD-TB), pre-XDR-TB, and XDR-TB patients aged 18 years or older treated between October 2019 to June 2022 were included. Chi-squared test or Kruskal Wallis test and multiple logistic regression were used to determine the risk factors associated with pre-XDR-TB and XDR-TB incidence. A total 16 patients of case group (15 pre-XDR-TB and one XDR-TB) and 116 SD-TB patients (control group) were included in the final analysis. Out of total patients within case group, 62.5% were male, 43.8% aged between 56–65 years, 62.5% graduated from high school or equivalent, and 25% were unemployed. The majority of patients had no comorbid (62.5%), had history of anti-TB treatment (93.8%), and had secondary resistance (93.8%). Multivariate analysis indicated that age (OR: 10.01; 95%CI: 1.49–66.91, p=0.018) and previous history of anti-TB treatment (OR: 216.25; 95%CI: 18.62–2511.60, p<0.001) were significantly associated with incidence of pre-XDR-TB and XDR-TB. This study highlights that having previous history of anti-TB treatment and older age are the predictors of the incidence of pre-XDR-TB and XDR-TB.
Effectiveness of smartphone application in increasing knowledge on COPD and its non-pharmacological management in COPD patients Adida, Fiony; Pandia, Pandiaman; Pradana, Andika; Tarigan, Amira P.; Ashar, Taufik; Dangana, Amos; Listyoko, Aditya S.
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.412

Abstract

Chronic obstructive pulmonary disease (COPD) is among top ten of the world's causes of death. The development of the “Paru Sehat” smartphone application is a positive initiative and might have the potential to improve the disease management of COPD, improve patient’s quality of life, and reduce complications associated with COPD. However, its effectiveness in improving the knowledge of the COPD patients is unknown. The aim of this study was to determine the effectiveness of “Paru Sehat” in increasing knowledge on COPD and its non-pharmacological management in COPD patients. A quasi-experimental study with a one-group pretest-posttest was conducted among stable COPD patients at Prof. Chairuddin Panusunan Lubis Hospital, Medan, Indonesia. Bristol COPD knowledge questionnaire (BCKQ) was used to assess the knowledge scores of the patients before and after exposure to the “Paru Sehat” twice a week for four weeks. A dependent Student t-test was used to compare the knowledge scores between pre- and post-intervention for both knowledge domains (i.e., knowledge on the disease and non-pharmacological management). Student t-test or one-way ANOVA were used to determine the association between patients’ characteristics and the knowledge scores within pre- and post-treatment. Our data indicated a significant improvement of the knowledge scores on disease between pre- and post-treatment (15.92±3.79 vs 19.56±3.68, p<0.001). The knowledge score on non-pharmacological management also increased significantly post-treatment (7.52±2.02) compared to pre-treatment (10.08±2.379), p<0.001. In addition, this study found that educational attainment was associated with the scores of both knowledge domains of which individuals with senior high school or higher education level had significantly improvement of knowledge scores. This study highlights that although “Paru Sehat” application could improve the knowledge on COPD and its non-pharmacological management, its effects are less effective among individuals with low educational attainment.
Factors associated with small airway obstruction in COVID-19 survivors: A cross-sectional study among health-care providers Aritonang, Minarni ES.; Pandia, Pandiaman; Pradana, Andika; Ashar, Taufik
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.437

Abstract

Coronavirus disease 2019 (COVID-19) has been identified for more than two years, yet studies assessing post-infection lung function are limited. Reports on lung function in COVID-19 patients indicate that patients have restrictive defects and small airway dysfunction that can persist and are not necessarily related to the severity of the disease. The aim of this study was to assess the incidence of small airway obstruction and its incidence-associated factors among COVID-19 survivors to better describe the long-term effects of COVID-19. A cross-sectional study was conducted among COVID-19 survivors who less than 50 years at Medan Adventist Hospital between 2020–2022. The data were collected through interview, direct assessment and respiratory examination. A total of 89 COVID-19 survivors were recruited of which the majority of them were female with a mean age of 32.6-year-old with the largest group was 19–30 years. The comorbidities found among the survivors were heart and thyroid disorders, with the most common symptom of post-COVID-19 was fatigue. Most of them had mild COVID-19. The mean forced mid-expiratory flow (FEF25–75%) was 96.3±20.22, with an incidence rate of small airway obstruction was 19.1%. Univariate and multivariate analyses indicated no significant association between age, gender, comorbidities, history of oxygenation during COVID-19 treatment, COVID-19 severity and the type of post COVID-19 syndrome symptoms with the incidence of small airway obstruction. In conclusion, among COVID-19 survivors who were less than 50 years old, those studied variables seems have less association with the incidence of small airway obstruction. Nevertheless, a further study with a bigger sample size is important to be conducted.
Co-Authors Adida, Fiony Adri Deslita Situmorang Afiani, Dina Ahmad Fandi Irfandi Alam Bakti Alam Bakti Keloko Alam Bakti Keloko, Alam Bakti Aliandri, Aliandri Amin, Mona N. Andika Pradana Andin Rizqika Aliunputri Andin Anggrainy, Putri Annisa Rizka Lestari Arfah Mardiana Lubis Ariantika, Ariantika Arifa Masyitah Panjaitan Arini Agustina Aritonang, Minarni ES. Asfriyati ,MKes Ayu Ulfah Nur Lubis Azmi Ervita Purnama Bambang Wispriyono Berta Kartina Bihar, Syamsul Br. Tobing, Netty Elida Bukit, Dhani Syahputra Chairul Anwar Chrestella, Jessy Chrestella, Jessy Dangana, Amos Darren Wan-Teck Lim Dealita Khairani Daulay Dedy Dwi Putra Delfi Delfitri Munir Delita Br Panjaitan Delvina Sinaga Dessy Irfi Jayanti Dessy Irfi Jayanti Destanul Aulia, Destanul Destanul Aulia, SKM., MBA., M.Ec., Ph.D Devi Nuraini Santi Devi Nuraini Santi Dinda Sekar Mentari Dody usman dr. Surya Dharma MPH Eka Lestari Mahyuni Eka Purnamasari Elisna Syahruddin Erman Munir Erna Mutiara Erna Mutiara ERNA VERONIKA SINAGA Eva Valentine Br. Hotang Evawany Aritonang Evawany Y Aritonang Evi Naria evi naria Evi Naria EVLINA SUZANNA, EVLINA Evo Elidar Harahap fadhil munthe Fadillah Ismy Faridah Hanum Rajagukguk Fathia Amanda Fatiyah Tul Khoir Nasution Fazidah Aguslina Siregar, Fazidah Aguslina Ferryan Sofyan Fithria Aldy Fransiska, Rosa Berlina Gerry Silaban Gerry Silaban Gerry Silaban Gifani Anastasya Gustina Fajarwati Sihombing Hamidah Fadhilah Hamonangan Nainggolan Hapsari, Sukma Harahap, Pahala Hanafi Harahap, Putri Wulandari Hasbullah Hasbullah Hasbullah Hasbullah Henny Maisara Sipahutar Heru Santosa Herwanto, H R Yusa Herwanto, H. R. Yusa Herwanto, R. Yusa Herwanto, Yusa hiswani . Hiswani Hiswani Ida Rizkia ika surya agustiani Ikhsan Ibrahim Imerlyn A Silitonga Indirawati, Sri Malem indra cahaya Indra Chahaya Irma Damayanti Irnawati Marsaulina Irnawati Marsaulina Ita Fitriyani Lubis Juanita Juanita Juanita Juita Asnipa Kananda, Vive Kezia Purba Khairiah . kiki agusty lamtiur junita bancin Launeta Maruyun Purba lidia oktavia Lim, Darren Wan-Teck Listyoko, Aditya S. Lita Sri Andayani Lorensia Eninta Lubis, Rodiah Rahmawaty Lubis, Yuliani M Lubis, Yuliani M. lulu marbun Marlina Renta Juyanti Butarbutar Melati Silvanni Nasution Melisah Pitri Siregar Merylanca Manalu Michico Eloista Br. Ginting Minar Indriasih Muhammad Harbi Praditya Muhammad Harbi Praditya Muhammad Syafii Mutiara Nauli Nadhira Marsha Audiva Harahap Nadia Arini Nahrisyah, Putri Nailatun Nadrah Namora Lumongga Lubis Nasution, Erizal Salam Putra Nasution, Nurhalimah Naysya Vitianoza Noni Novisari Soeroso Noni Novisari Soeroso Nurhandini, Astri nurma irama Nurmaini . Nurmaini Nurmaini Nurmaini Nurmaini Nurmaini Nurmaini Nurmaini Nurmaini Nurmaini Nurmaini olivia via Osareniro, Osakue E. Pandia, Pandiaman Pandiaman Pandia Parinduri, Anggi Isnani Parluhutan Siagian Pinem, Agung Haganta Purba, Jenny Marlindawani Putra, Aldi Maulana Putra, Muhammad Yusuf Adira Putra, Wahyu Medsa Yeltas Putri, Syafreni Annisa Ayu R.Kintoko Rochadi Rahayu Lubis Rahayu Lubis Rahmadani Sitepu Rahmi Wardani Rambe, Alvin Rambe, Andriana Yunita Murni Rambe, Andrina Yunita Murni Rasmaliah ,MKes Rasmaliah . reni indra aristi Rio Ferdi Yuandra riris lumban Risanti Febrine Ropita Situmorang Rizka Fiqih Ertika Rizky, Handan Rochadi, Raden Kintoko Rocky Malindo Sidabutar saddam musthofa Sagala, Irwan Pernandi Samuel Marganda Halomoan Manalu Sari, Masitha Dewi Setiaty Pandia, Setiaty Siagian, Novi Andriani Silvia, S Simanjuntak, Amran Simanjuntak, Saurma O S Simanjutak, Yohana Sinaga, Bintang Yinke Magdalena Sinaga, Bintang YM. Sinulingga, Herison E. Siregar, Annisa Febriana Siregar, Kamal Basri Siregar, Nur Khaidah Siregar, Nurul Rahmah Sitepu, Rahmadani Siti Khadijah Siti Khadijah Nasution siti rahmah Siti Zahara Nasution, Siti Zahara Sitompul, Indah Sari Sormin, Cynthia sri dewi puspita Sri Malem Indirawati Sufia Idya Suriani Gultom Surya Darma Surya Dharma Syahrani, Fajrinur Syarani, Fajrinur Tarigan, Amira P. Tarigan, Amira Permatasari Tarigan, Lina Tarigan, Setia Putra Tatiana, Melza Thomson Siahaan Tony Wibowo Tukiman Tukiman Tukiman Umi Salmah Utama, Surya Verarica Silalahi, Verarica Winni R.E Tumanggor Wirsal Hasan Wirsal Hasan Yenni Yulfida Harahap Yudhi Pratama Yuslina FNB Siahaan Yusniar Zahara, Devira Zikri Putra Lan Lubis Zulfendri Zulfendri Zulfendri Zurhayati, Zurhayati