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Pengaruh Ekstrak Daun Sukun (Artocarpus altilis) Terhadap Kepadatan Kolagen dalam Proses Penyembuhan Luka Eksisi Tikus Putih (Rattus norvegicus) Cahya, Rizka Wulan; Yudaniayanti, Ira Sari; Wibawati, Prima Ayu; Yunita, Maya Nurwartanti; Triakoso, Nusdianto; Saputro, Amung Logam
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (679.313 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.25-30

Abstract

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh ekstrak daun sukun (Artocarpus altilis) terhadap kepadatan serabut kolagen dalam penyembuhan luka eksisi pada tikus putih (Rattus norvegicus). Dua puluh ekor tikus jantan dibagi secara acak menjadi lima kelompok, terdapat kontrol negatif (K-) yang diberikan basis salep, kontrol positif (K+) yang diberikan povidone iodine 10%, kelompok perlakuan (P1, P2, P3) yang diberikan salep ekstrak daun sukun 6,25%; 12,5%; dan 25%. Terapi diberikan sekali sehari selama empat belas hari. Hasil uji nonparametrik Kruskal-Wallis menunjukkan perbedaan nyata (p<0,05) dan dilanjutkan dengan uji Mann-Whitney. kelompok kepadatan kolagen P1, P2, dan P3 tidak berbeda nyata (p>0,05), tetapi berbeda nyata dengan kelompok K- dan K+. Kesimpulan dari penelitian ini adalah ekstrak daun sukun efektif untuk meningkatkan kepadatan kolagen dalam proses penyembuhan luka eksisi.
Efektivitas Krim Ekstrak Buah Naga Merah (Hylocereus polyrhizus) dalam Meningkatkan Jumlah Sel Fibroblas Luka Bakar Derajat II pada Tikus Putih (Rattus norvegicus) Rahmadhani, Nurmitasari; Yudaniayanti, Ira Sari; Saputro, Amung Logam; Triakoso, Nusdianto; Wibawati, Prima Ayu; Yudhana, Aditya
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (876.884 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.65-75

Abstract

Tujuan penelitian ini adalah untuk mengetahui efektivitas krim ekstrak buah naga merah (Hylocereus polyrhizus) dalam meningkatkan jumlah sel fibroblas luka bakar derajat II pada tikus putih (Rattus novegicus). Dua puluh ekor tikus putih (Rattus novegicus) jantan dibagi menjadi lima kelompok perlakuan dengan jumlah empat ulangan setiap kelompok. Semua tikus tersebut diinduksi dengan luka bakar derajat II. Kelompok kontrol negatif (K-) diterapi dengan basis krim minyak dalam air, Kelompok kontrol positif (K+) diterapi dengan Bioplacenton®, kelompok perlakuan diterapi dengan krim ekstrak buah naga merah (Hylocereus polyrhizus) dengan konsentrasi P1 7.5%, P2 15%, dan P3 30%. Terapi diberikan dua kali dalam sehari selama 10 hari. Hasil uji Kolmogorov-Smirnov menunjukkan data terdistribusi normal (p>0.05) dilanjutkan dengan uji Oneway ANOVA yang menunjukkan adanya perbedaan nyata dari tiap kelompok perlakuan (p<0.05) dan dilanjutkan dengan uji Post-Hoc LSD. Rata-rata jumlah fibroblas setiap kelompok perlakuan menunjukkan bahwa kelompok K- dan K+ berbeda nyata dengan kelompok P1, P2 dan P3. Jumlah sel fibroblas terbanyak didapati pada kelompok P2. Kesimpulan dari penelitian yang telah dilakukan adalah krim ekstrak buah naga merah (Hylocereus polyrhizus) dapat meningkatkan jumlah sel fibroblas luka bakar derajat II pada tikus putih (Rattus norvegicus).
Pengaruh Kitosan Udang Secara Topikal Terhadap Kepadatan Kolagen dalam Penyembuhan Luka Eksisi pada Tikus Putih Prastika, Dinda Dwi; Setiawan, Boedi; Saputro, Amung Logam; Yudaniayanti, Ira Sari; Wibawati, Prima Ayu
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (839.412 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.101-107

Abstract

Luka eksisi adalah luka yang permukaan kulit dan lapisan bawahnya akan terpotong sampai kedalaman yang bervariasi dapat terjadi secara sengaja atau tidak sengaja. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh chitosan kulit udang terhadap kepadatan kolagen dalam proses penyembuhan luka eksisi pada tikus putih. Sebanyak dua puluh ekor tikus putih (Rattus norvegicus) jantan dibagi ke dalam lima kelompok perlakuan yaitu K- luka eksisi dengan pemberian basis salep, K+ (luka eksisi+10% povidone iodine), P1 (luka eksisi+salep chitosan kulit udang 1.5%), P2 (luka eksisi+udang salep kulit kitosan 2.5%), dan P3 (luka eksisi+kitosan kulit udang 5%). Hasil perhitungan persentase kepadatan kolagen dianalisis oleh Kruskal-Wallis yang menunjukkan perbedaan signifikan (p<0.05) dan dilanjutkan dengan uji Mann-Whitney U. Kelompok K+, K- dan P1 memiliki perbedaan signifikan dalam kepadatan kolagen pada P2, dan kelompok P3 (p<0.05). Kesimpulan dari penelitian ini kitosan berpengaruh terhadap kepadatan kolagen dengan dosis 5%.
An Evaluation of Nutritional Factors on The Prevalence of Urolithiasis in Cats at The Veterinary Teaching Hospital, Universitas Airlangga During 2017-2019 Mahdi, Daffa Amanul; Sardjana, I Komang Wiarsa; Yudaniayanti, Ira Sari; Estoepangestie, Agnes Theresia Soelih; Triakoso, Nusdianto; Primarizky, Hardany
Jurnal Medik Veteriner Vol. 6 No. 2 (2023): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss2.2023.180-184

Abstract

Stones, or uroliths, in the urinary tract cause a disorder called urolithiasis. Patients with urolithiasis may experience blockage and possibly mortality; therefore, prompt treatment is imperative. This study aimed to investigate the prevalence of urolithiasis and its nutritional association in cats treated at the Veterinary Teaching Hospital, Universitas Airlangga during 2017-2019. Data was collected from the secondary resource from the medical report and the factor of feed nutrition involved fiber, protein, fat, and moisture. Data was analyzed using logistic regression to determine the influence of nutrition on the prevalence of urolithiasis in cats in the respective period. The findings indicated that in 2017, urolithiasis prevalence was 0,96%; in 2018, it was 5,55%; and in 2019, it was 0,91%. Meanwhile, it was revealed that the prevalence of urolithiasis was not significantly impacted by feed nutritional variables.
The Effect of Apis dorsata Honey Treatment on Calcium Levels of Mandibular Bone in Ovariohysterectomized Wistar Rats Rohmah, Siti Nur; Yudaniayanti, Ira Sari; Primarizky, Hardany; Hastutiek, Poedji
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.1-7

Abstract

This study aimed to evaluate the efficacy of Apis dorsata honey on calcium levels in the mandibular bone of Wistar rats after ovariohysterectomy as an animal osteoporosis model for treating cases of osteoporosis. This study used 20 female rats, which were divided into five treatment groups with four replications. SHAM was the negative control group; OH was the ovariohysterectomized group without treatment as a positive control; the AD1, AD2, and AD3 groups were ovariohysterectomized rats with A. dorsata honey at doses of 1 g/kg bw, 2 g/kg bw, and 4 g/kg bw for 84 days. After 84 days of treatment, the left mandibular bones of the rats were collected, weighed, and stored in 10% neutral buffered formalin. Calcium levels were calculated using proximate analysis. The results showed a decrease in bone calcium levels in the ovariohysterectomy group, the highest results were in the SHAM group, and the lowest results were in the AD3 group. It can be concluded that the administration of A. dorsata honey could not maintain the calcium level of the mandibular bone in the ovariohysterectomized Wistar rats.
The Efficacy of Madeira Vine Leaf Extract Combined with Turmeric Rhizome Extract Gel Topically on Second-Degree Burn Wound in Albino Rats Hisyam, Mirza Atikah Madarina; Yuniarti, Wiwik Misaco; Theresia, Sis Wisnuarti; Yudaniayanti, Ira Sari; Lukiswanto, Bambang Sektiari; Sudjarwo, Sri Agus; Widiyatno, Thomas Valentinus
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.91-98

Abstract

Burns is now considered one of the most destructive forms of trauma affecting humans and animals. This study aimed to determine the effect of Madeira vine leaf extract combined with 2% Turmeric rhizome extract (MVLTR) gel administered topically on second-degree burn wound in albino rats based on the number of fibroblasts. A total of 25 male rats weighed 200–300 grams were divided into five groups i.e. (C-) was normal skin, (C+) was burn and treated using 1% silver sulfadiazine, (T1) was burn and treated using 1.25% MVLTR gel, (T2) was burn and treated using 2.5% MVLTR gel, and (T3) was burn and treated using 5% MVLTR gel. The burn wound was performed on the right gluteus of rats, and the therapy was applied twice a day topically, starting after the burn wounds were made. Skin samples were collected on day 15. The histopathological examination was performed by counting fibroblast cells and then analyzed using One-way ANOVA, continued with the Duncan test. Based on the results showed that the C- group was significantly different compared to C+, T1, T2, and T3 groups. C+ had a significant difference with the T1 and T3 groups, meanwhile not significantly different from the T2 group. T2 was not significantly different from the C+ and T3 groups. In conclusion, MVLTR gel at 5% concentration has the potential to be an effective treatment for second-degree burns, as indicated by the increased number of fibroblasts.
Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats Panggabean, Rosenna Tiara; Sudjarwo, Sri Agus; Ma'ruf, Anwar; Widiyatno, Thomas Valentinus; Yudaniayanti, Ira Sari; Kurnijasanti, Rochmah; Khairullah, Aswin Rafif
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.107-115

Abstract

Burns not only damage skin locally but generally affect the body system and have been related as the secondary cause of death. Burns can be effectively treated with a topical drug to prevent chronic inflammation. Burn wound healing is really important for ensuring overall health and well-being. This study aimed to determine the effect of Sauropus androgynous leaves extract gel on the number of fibroblasts, fibrocytes, and collagen density on burn wound healing in albino rats. A total of 50 male albino rats were randomly divided into five groups i.e. (C-) was normal skin, (C+) was skin burn treated with placebo, (T1) was skin burn treated with 2.5% of S. androgynous leaves extract gel, (T2) was skin burn treated with 5% of S. androgynous leaves extract gel, and (T3) was skin burn treated with 10% of S. androgynous leaves extract the gel. The amount of 25 albino rats' skin samples were collected on the 8th day, and the remaining samples were collected on the 15th day. The results showed that 10% of S. androgynous leaves extract gel improved faster, as indicated by the increased number of fibroblasts, fibrocytes, and collagen density. This study can be concluded that 10% of S. androgynous leaves extract gel was the effective dosage to increase the number of fibroblasts, fibrocytes, and collagen density in burn wound healing.
Strategic Infectious Diseases in Beef Cattle in Balongpanggang during 2023 Yuniarti, Wiwik Misaco; Lukiswanto, Bambang Sektiari; Setiawan, Boedi; Yudaniayanti, Ira Sari; Triakoso, Nusdianto; Hisyam, Mirza Atikah Madarina; Susanti, Lina; Niken Hastuti, Apriliwiyani; Sudjono, Budi Santoso
Jurnal Medik Veteriner Vol. 7 No. 2 (2024): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol7.iss2.2024.362-369

Abstract

Strategic infectious animal diseases have a great impact on the national economy as they may cause great economic loss, public anxiety, and high mortality. In Indonesia, among the diseases considered as strategic infectious animal diseases is foot and mouth disease (FMD). This study reported the incidence of strategic infectious animal diseases in Balongpanggang district during 2023. Throughout 2023, FMD only accounted for 4% of the total diseases of the year and was the only strategic infectious animal disease reported that year. Meanwhile, bovine ephemeral fever (BEF) incidence reached 57% (876/1546) of the total diseases in beef cattle in 2023. In addition to BEF, official veterinary services reported a total case of 1546 throughout 2023 that comprises; diarrhea (99), limping (24), helminthiasis (91), ectoparasite (11), hematochezia (3), wound (3), mastitis (4), allergy (1), dystocia (28), vaginal prolapse (11), dermatitis (45), enteritis (27), tympani (11), scabiosis (122), arthritis (67), ophthalmic problem (11), endometritis (1), uterine retention (13), indigestion (2), pneumonia (21), hypoglycemia (5), abscess (21), ovariohysterectomy (1), orchitis (1), intoxication (1), and papilloma (1). In conclusion, the only strategic infectious animal disease reported in 2023 in Balongpanggang was FMD with the incidence as high as 3% as compared to the non-strategic infectious animal diseases, BEF, which reached 54% of the total cases during 2023.
Screening of Blood Glucose Concentration in Domestic Cat (Felis Catus) Based on Body Condition Score, Breed, and Sex Using Portable Blood Glucose Meter Billa, Lutfiah Annisa; Triakoso, Nusdianto; Rachmawati, Kadek; Yuniarti, Wiwik Misaco; Aksono, Eduardus Bimo; Yudaniayanti, Ira Sari
Journal of Basic Medical Veterinary Vol. 12 No. 1 (2023): Journal of Basic Medical Veterinary, June 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v12i1.42246

Abstract

Type 2 diabetes mellitus (T2DM) is a common endocrine disease in domestic cats. Breed, sex, being overweight to an extent of obesity are predisposing factors for developing T2DM. One of the most common laboratory analyses conducted to confirm this disease is blood glucose concentrations. The aim of this research is to determine blood glucose concentration in domestic cats based on BCS, breed, and sex using a portable blood glucose meter. Research samples were obtained by taking blood samples from the marginal ear vein of 131 domestic cats that matched the sample's criteria, took at 2-hours post prandial, and drip onto the Sinocare strip. The results showed that the average blood glucose concentration was in the normal range, with a total of ideal (BCS ≥3/5) domestic cats (n=43) was 75.74 mg/dL, overweight (BCS ≥4/5) domestic cats (n=44) was 78.23 mg/dL, obese (BCS ≥5/5) domestic cats (n=44) was 89.66 mg/dL, male (n=51) was 80.57 mg/dL, female (n=80) was 81.69 mg/dL, Mixed Breed (n= 119) was 81.03 mg/dL, Angora (n=5) was 84.20 mg/dL, Persian (n=6) was 81.50 mg/dL and Ragdoll (n=1) was 92 mg/dL. Pearson correlation showed BCS (r=0.403; p= 0.000) had a moderate, positive, and significant correlation with blood glucose concentration in domestic cats. Meanwhile, the results of Kendall's Tau correlation showed that breed (p=0.740) and sex (p=0.555) had insignificant correlation with blood glucose concentration in domestic cats.
Comparison of reproductive performance of Ongole cross and Ongole-Limousin cross in Bekri district, Central Lampung regency, Lampung province, Indonesia Sukma, Puspa Permata; Ismudiono Ismudiono; Sri Mulyati; Pudji Srianto; Sri Pantja Madyawati; Ira Sari Yudaniayanti; Abdullah Hasib
Ovozoa: Journal of Animal Reproduction Vol. 13 No. 1 (2024): Ovozoa: Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v13i1.2024.9-17

Abstract

This study aims to compare the reproductive performance of the Ongole cross (PO) and Ongole-Limousin cross (Limpo) on smallholder farmer in Bekri district, Central Lampung regency, Lampung province, a Indonesia. This study used 30 PO cows, 30 Limpo F1 (first filial) cows and 30 Limpo F2 cows. Sample cows had at least two parities and had never had a history of reproductive disorders. This study used primary and secondary data related to sample cows. Primary data was obtained from interviews with farmers and secondary data was obtained from the Department of Plantations, Livestock and Fisheries of Central Lampung regency, and inseminator recording. Data were described descriptively and analyzed using a one-way Analysis of Variance in Statistical Product and Service Solution (SPSS) version 23. The result showed that the services per conception of Limpo F2 cows was higher (p <0.05) than for PO and Limpo F1 cows. Days open and calving interval for Limpo cows (F1 and F2) were longer (p <0.05) than for PO cows. Days open and calving interval for Limpo F1 cows were not significantly different (p >0.05) than for Limpo F2 cows. Reproductive performance of PO cows was better compared to Limpo F1 and Limpo F2 cows. However, there was a data discrepancy between reproductive performance and data on rearing systems, feed quality, and signs of estrus observed by farmers. It could be concluded that PO cows had better reproductive performance than Limpo cows.
Co-Authors A Ashiila Tsabita A'la, Rofiqul Abdul Samik, Abdul Abdullah Hasib Abdullah Hasib Adikara, Yuanara Augusta Rahmat Agnes Theresia Soelih Estoepangestie Agus Budi Santoso Aisyah Novasari Aisyah, Rimala Aksono HP., Eduardus Bimo Al arif, Mohammad Anam Amalia Rosydinasari Rosydinasari Aswin, Ahmad Bachtiar, Harris Yudhanta Bambang Sektiari Lukiswanto Billa, Lutfiah Annisa Boedi Setiawan Budi Utomo Cahya, Rizka Wulan Dewi Mariyam Diyantoro Diyantoro, Diyantoro Djoko Galijono Eka Pramyrtha Hestianah, Eka Pramyrtha Emy Koestanti Sabdoningrum Endah Paraswati Farizky Rusnalendra, Tegar Fatin Fadhilah Hasib Fedik Abdul Rantam Fidyah Fitrawati, Fidyah Hadiah Fitriyah Haeriah Hani Plumeriastuti Hartiningsih - Helen Susilowati, Helen Hidanah, Sri Hisyam, Mirza Atikah Madarina Imam Mustofa Immelda, Kicky Hanis Indira, Sitti Az-Zahra Inggarsetya Syah Audini Ismudiono Ismudiono Ivanalee, Angela Swasti Iwan Sahrial Hamid Kadek Rachmawati Karo-karo, Desniwaty Khairullah, Aswin Rafif Koesnoto Supranianondo Kuncoro Puguh Santoso Kuncorojakti, Suryo Kusnoto Kusnoto, Kusnoto Legowo, Djoko LINA SUSANTI Lucia Tri Suwanti, Lucia Tri M. Zainal Arifin Ma'ruf, Anwar Mafruchati, Maslichah Mahdi, Daffa Amanul Mardatillah, Meidy Miarsono, Sigit Mirni Lamid Moh Anam Al Arif Mufasirin Muhammad Huda Ramadhan Ibrahim Niken Hastuti, Apriliwiyani Nove Hidajati Nunuk Dyah Retno Lastuti Nusdianto Triakoso Panggabean, Rosenna Tiara Poedji Hastutiek Prastika, Dinda Dwi Primarizky, Hardany Pudji Srianto Putri, Desak Ketut Sekar Cempaka Putrianirma, Rizki R.T.S Adikara, R.T.S Adikara Rafif Galih Satria Rahmadhani, Nurmitasari Rahmahani, Jola Rahmawati, Kadek Ratna Damayanti Rochmah Kurnijasanti Rodprasert, Watchareewan Rohmah, Siti Nur Rosyada, Zulfi Nur Amrina Salsabilla Abani Samsi Yordan Santoso, Kuncoro P. Saputro, Amung Logam Sardjana, I Komang Wiarsa Sarmanu, Sarmanu Setiawan Koesdarto Setiawati Sigit Siti Nur Rohmah Soeharsono Soeharsono Soeharsono Sofyan, Miyayu Soneta Sri Hidanah Sri Mulyati Sri Mumpuni Sri Mumpuni Sosiawati Sri Pantja Madyawati Sudjono, Budi Santoso Suherni Susilowati Sukma, Puspa Permata Sukmanadi, M Sunarso, Agus Susilawati, Helen Suwarno Suzanita Utama Theresia, Sis Wisnuarti Tjuk Imam Restiadi Triaoso, Nusdianto Vandarischa Prameswari, Revita Wahyudi, Nurul Tri Warsito, Sunaryo Hadi Wibawati, Prima Ayu Widiyatno, Thomas Valentinus Widya Paramita Widya Paramita Lokapirnasari Wijaya, Andi Yasmin Winda Ayu Puteri Sumartono Wiwik Misaco Yuniarti Wiwik Misaco Yuniarti Wurlina, W Yudhana, Aditya Yunita, Maya Nurwartanti Yunus, Muchammad