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Heru Setiawan
Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Universitas Negeri Semarang
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The Comparison of IC50 of Suji (Pleomele angustifolia) which is Extracted by Different Solvent Bahri, Syamsul; Setiadi, Dadi; Lestari, Tri Ayu; Setiawan, Heru; Hakim, Muhammad Alfianul; Cahyadi, Lalu M. Zidan
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.9559

Abstract

The Determination both of IC50 of Suji (Pleomele angustifolia) and its phytochemical subtances content which extracted by a different solvent has been conducted. The aim of this research is to determine kind of solvent which achieve better result. The method used is laboratory experiments for phytochemical screening and antioxidant activity assay. This research consists of 2 (two) stages. First stage aims to obtain extract of suji by using certain solvent, and the second stage is carried out to examine  secondary metabolite compounds of the extract using phytochemical screening and then to determine the antioxidant activity of extract using the DPPH method. This research used  2 kinds of solvent, ethanol plus ethyl acetate in the first sample, and the second one by ethanol only. Sample which extracted by ethanol plus ethyl acetate positively contains terpenoids, whereas flavonoid and  alkaloids are detected in a significant number. The DPPH test results obtained the equation y = 0.3492x + 12,059, indicating that the antioxidant activity of suji which extracted by ethanol plus ethyl acetate is classified as moderate as the IC50 value of the extract of suji is108,65 ppm. The other sample which extracted just by ethanol also contains terpenoid, flavonoid, and alkaloid, but in a greater number. In the second sample also detected steroid compound which undetectable in the first sample. DPPH score in the second sample which extracted  by ethanol. is y= 06352x + 18, 786. By using this equation we found 49.14 ppm as IC50 score. This score is classified as strong activity. This result shows that antioxidant activity of the second extract is stronger than the first one. The result also meaning that ethanol is more effective in extracting phytochemical compounds of suji than ethanol plus ethyl acetate.
Imunopatomekanisme Demam Berdarah Dengue (DHF) Hartanto, Deddy; Setiawan, Heru
Calvaria Medical Journal Vol 3 No 1 (2025): Edisi Juni 2025
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v3i1.211

Abstract

Latar Belakang: Demam Berdarah Dengue (DBD) merupakan komplikasi berat infeksi virus dengue yang dipicu oleh disregulasi imun selama infeksi sekunder heterolog, dengan mortalitas mencapai 20% tanpa penanganan. Tujuan: Mengkaji mekanisme imunopatogenesis DBD, termasuk peran ADE, cytokine storm, dan gangguan hemostasis, serta implikasinya untuk tata laksana klinis.  Metode: Tinjauan naratif menggunakan database PubMed, ScienceDirect, dan repositori institusi (2007–2023) dengan kata kunci: “imunopatogenesis dengue”, “ADE dengue”, “cytokine storm DHF”.  Hasil: Antibody-Dependent Enhancement (ADE) memfasilitasi masuknya virus ke monosit/makrofag, memicu produksi TNF-α/IL-6 berlebihan. Reaktivitas silang sel T (original antigenic sin) dan cytokine storm menyebabkan kebocoran plasma yang ditunjukkan dengan peningkatan kadar hematokrit >20%) dan trombositopenia (<100.000/μL). Infeksi sekunder meningkatkan risiko DBD 15–80 kali. Kesimpulan: Imunopatogenesis Demam Berdarah Dengue (DBD) bersifat multifaktorial. Deteksi dini hemokonsentrasi dan terapi imunomodulator berbasis sitokin merupakan strategi potensial.
Analysis Questioning Skills of Biology Education Student Based on Different Academic Abilities and the Correlation With Metacognitive Skills Kusuma, Anindita Suliya Hangesti Mandra; Rasmi, Dewa Ayu Citra; Artayasa, I Putu; Ilhamdi, M Liwa; Setiawan, Heru
Journal of Classroom Action Research Vol. 7 No. 2 (2025): Mei 2025
Publisher : Program Studi Magister Pendidikan IPA, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jcar.v7i2.10732

Abstract

The aim of this research is to determine the questioning skills of Biology Education students based on different academic abilities and their correlation with metacognitive skills. This study employs a mixed methods design. The sample in the study consists of biology education students from the Faculty of Teacher Training and Education, University of Mataram. The instruments used in this research include the Questioning Skills Instrument and an Achievement test to measure metacognitive skills. The data analysis used in this research includes descriptive and inferential statistical analysis (correlation and regression). The results of the qualitative analysis using descriptive statistics show that the questioning skills of students with low academic performance mostly remain at level C2 (comprehension questions), comprising 58% of the questions, and C1 (recall questions), comprising 38% of the questions. A small proportion were able to formulate questions at level C3 (application questions), comprising 15% of the questions, and only 1% were able to formulate questions at level C4 (analysis questions). For students with high academic performance, most of the questioning skills were at level C3 (application questions), comprising 36.67% of the questions, and C2 (comprehension questions), comprising 35.56% of the questions. Additionally, 18.89% of the questions reached level C4 (analysis questions), and 3.33% reached level C5 (evaluation questions). Only a small proportion formulated questions at level C1 (recall questions), comprising 1.11% of the questions. The analysis of the relationship between questioning skills and metacognitive skills indicates that there is a relationship between students' questioning skills and metacognitive skills when using the Reading Concept Mapping-Reciprocal Teaching (ReMap-RT) learning model, with a correlation coefficient of 0.868 (high). The direction of the relationship between questioning skills and metacognitive skills is positive. The coefficient of determination (r²) is 0.754, which explains that the variability in students' metacognitive skills is determined by 75.4% of the questioning skills. The significance value of this regression is also used to determine whether the regression equation can be used for prediction. If the significance value of the regression is less than the determined significance level, then the regression equation can be used for prediction. Based on the analysis results, the regression significance value is 0.00 < 0.05, so it can be concluded that the regression equation can also be used for prediction. The regression equation for the relationship between questioning skills and metacognitive skills of students using the Reading Concept Mapping-Reciprocal Teaching (ReMap-RT) learning model is Ŷ = 38.791 + 3.185X.
Inovasi Metode Gallery Walk pada Pembelajaran Online dengan Aplikasi Artsteps selama Pandemi Covid-19 Setiawan, Heru; Riandi, Riandi; Supriatno, Bambang
Asatiza: Jurnal Pendidikan Vol. 3 No. 2 (2022): Asatiza: Jurnal Pendidikan
Publisher : STAI Auliaurrasyidin Tembilahan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46963/asatiza.v3i2.526

Abstract

The purpose of this study is to analyze students’ response of the Gallery Walk Method with the innovation of ArtSteps of Plant and Animal Classification and evaluate the obstacles in online learning during the Covid-19 pandemic. This research was conducted in grade X which consists of 15 students in Senior High School of Global Mandiri Jakarta. The instrument is the questionnaire and interviews. Based on the results of the questionnaire, we found that most students gave positive responses. More than three-quarters of students can understand the plant and animal classification material well, can express their creativity, and are more active during online learning. Students are also satisfied with their peers' presentations. According to the result of the Interview, the biggest challenge for the implementation is the internet network and the lack of real interaction with classmates. The recommendation is that students need to discuss each station for at least 15 minutes and twice in each station of Artsteps for more effectiveness.
Program Pendidikan sebagai Upaya Pemenuhan Kebutuhan Peserta Didik Dalam Meningkatkan Prestasi Akademik Setiawan, Heru; Hakim, Muhammad Nur; Tipa, Kurniayati
At Tadbir: Islamic Education Management Journal Vol. 3 No. 1 (2025): Juni
Publisher : Islamic Education Management Study Program of STIT al Urwatul Wutsqo Jombang, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54437/attadbir.v3i1.1941

Abstract

This study aims to examine the implementation of educational programs at SMA Negeri 2 Mojokerto and analyze its role in meeting the needs of students in order to improve academic achievement. The research method used is qualitative descriptive with a case study approach. Data were collected through observation, interviews, and documentation. The results of the study indicate that the preparation of educational programs at SMA Negeri 2 Mojokerto was carried out carefully and systematically at the beginning of the semester, taking into account the needs of students. Educational programs as an effort to meet the needs of students in improving academic achievement include tutoring activities, independent learning activities, project-based learning, and guidance and counseling. These programs are designed to provide comprehensive support so that students can achieve their academic potential optimally
Sosialisasi Hasil Brand Audit Sampah Pendakian kepada Masyarakat di Jalur Pendakian Tetebatu, Taman Nasional Gunung Rinjani Santoso, Didik; Adawiyah, Marosa Robi’atul; Sakaroni, Rubiyatna; Setiawan, Heru
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 1 (2025): Januari-Maret 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i1.12097

Abstract

Permasalahan sampah di jalur pendakian Tetebatu, Taman Nasional Gunung Rinjani, menunjukkan perlunya keterlibatan masyarakat lokal dalam upaya pengurangan limbah konsumsi. Kegiatan sosialisasi ini dilaksanakan di Desa Tetebatu, Kecamatan Sikur, Kabupaten Lombok Timur, dan bertujuan untuk menyampaikan hasil analisis brand audit barang berpotensi sampah sebagai bentuk edukasi lingkungan kepada masyarakat. Sosialisasi dilakukan selama satu hari dan melibatkan warga sekitar jalur pendakian, seperti porter, pedagang, dan pelaku usaha lokal. Materi disampaikan melalui visualisasi data serta diskusi terbuka mengenai produk-produk yang paling banyak menyumbang sampah di jalur pendakian. Hasil kegiatan menunjukkan peningkatan pemahaman masyarakat terhadap dampak lingkungan dari produk sekali pakai, serta munculnya inisiatif penggunaan kemasan yang lebih ramah lingkungan. Kegiatan ini menunjukkan bahwa penyampaian hasil riset dalam format sederhana dan partisipatif dapat menjadi strategi efektif dalam mendorong pelestarian lingkungan berbasis komunitas.
KESANTUNAN BERBAHASA DALAM PERCAKAPAN ANTARMAHASISWA SEMESTER DELAPAN STKIP PGRI PONOROGO Nugroho, Rahmad; Wardiani, Ririen; Setiawan, Heru
Jurnal Bahasa dan Sastra Vol 8 No 1 (2021): Januari
Publisher : STKIP PGRI Ponorogo Press

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Abstract

In communicating, the speaker better uses polite language, because it will maintain speaker’s dignity and respects the hearer. Further, it can create smooth and pleasant communication. The purpose of this study is to find a forms of language politeness and their meaning in conversations among eight semester students of STKIP PGRI Ponorogo in 2019. This research is a descriptive research that uses a qualitative approach. The data collection method used in this study is the observation method. In this study, each speech is analyzed based on the theory of politeness from Leech (in Rahardi, 2005: 59) as follows: tact maxim, generosity maxim, approbation maxim, modesty maxim, agreement maxim, and sympathy maxim. As a result, the researcher found nine tact maxims, two tact maxim violations, one approbation maxim, two sympathy maxims, one sympathy maxim violation, two generosity maxims, nine consensus maxims, and three modesty maxims.
STRATEGI KESANTUNAN BERBAHASA DALAM FILM ASSALAMUALAIKUM CALON IMAM Setiyono, Tatang; Wardiani, Ririen; Setiawan, Heru
Jurnal Bahasa dan Sastra Vol 8 No 1 (2021): Januari
Publisher : STKIP PGRI Ponorogo Press

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Abstract

Language is used by human to communicate and interact each other.Due to the importance of language use in society, pragmatics become an important analysis part One of the studies in pragmatics discusses about the language politeness. This research focused on the principle of language politeness using Geoffrey Leech’s theory, six maxims, namely the tact maxim generosity maxim, Approbation Maxim, Modesty maxim, Agreemen maxim, Sympaty maxim. This study aimed to describe the strategy of language politeness in the film Assalamualaikum Calon Imam. The method used in this research was descriptive qualitative. This study decribed the principles of politeness in films. The object of study in this research was film. The data used in this study were the utterances of the main and supporting characters in the film. The research results that the six maxims were spoken by the main character and the supporting character. The conclusion of this research was that the film players obey the politeness strategy in the form of maxims. There are six maxims obeyed in the speech, namely maxim generosity maxim, Approbation Maxim, Modesty maxim, Agreemen maxim, Sympaty maxim.
Kajian Stilistika Teks Lagu dalam Album Untukmu Selamanya Karya Band Ungu Lestari, Septiani; Wardiani, Ririen; Setiawan, Heru
Jurnal Bahasa dan Sastra Vol 8 No 2 (2021): Juli
Publisher : STKIP PGRI Ponorogo Press

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Abstract

This research is motivated by the interesting use of word choice or diction and figurative language used by Ungu band. For this reason, this study aims to analyze the use of diction and figurative language contained in the album Untukmu Selamanya. The method used is descriptive with a literature review design. Data are collected by using the note-taking technique. The data are analyzed by employing descriptive technique including the following steps; data selection, coding, data classification, data description, and data interpretation. The data source of this research is the three song texts on the album Untukmu Selamanya by Ungu band. The result of the analysis shows that the majority of the diction contained in the song is connotative. This is a manifestation of the song composer’s creativity when creating lyrics. Another finding is the use of figurative language, synecdoche and simile with the theme of romance and sadness.
KONFLIK BATIN TOKOH MUSTAFA DALAM NOVEL TEMPAT PALING SUNYI KARYA ARAFAT NUR Razzaq, Agung Abdul; Sutejo, Sutejo; Setiawan, Heru
Jurnal Bahasa dan Sastra Vol 9 No 1 (2022): Januari
Publisher : STKIP PGRI Ponorogo Press

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Abstract

Literature is the art of human thought. Literary works are mostly written in beautiful language and providing general insight into human problems and their conflicts. Conflict is essentially a problem that occurs in society. Conflict occurs because of a need and desire that is not achieved, then an unpleasant feeling arises inside. This study aims to describe the inner conflict of Mustafa’s character in Arafat Nur’s novel Tempat Paling Sunyi. The inner conflict in Mustafa’s character is analyzed using Adler’s theory of Individuality Psychology. Adler’s theory is a psychological theory of personality which in his view problems are always social, so that personality is defined as a character or character that stands out in humans. Therefore, the research approach used is a qualitative descriptive method. The data in this study are excerpts in the from of word and sentences in Arafat Nur’s novel Tempat Paling Sunyi. From the result of the study it can be concluded that in Arafat Nur’s novel Tempat Paling Sunyi, there are six inner conflicts according to Alfred Adler’s view, as follows: struggle to be superior, subjective perception, unity of personality, social interest, creativity, and life style.
Co-Authors Achwan, Achwan Adawiyah, Marosa Robi’atul AHMAD JUNAEDI Aini, Jannatul Alhafizin, M. Ananda, Liandry Dea Dwi Andreas Priyono Budi Prasetyo ansori ansori Aprianto, Iwan Arzam, Ismail Zaid Asmaul Husna, Fika Astuti, Andriani Widi Astuti, Julya Aulia, Alfina Azhar Affandi Aziz Amrullah, Aziz B L, Abdurahman Berbudi Baihaqi, Muhammad Iqbal Baiq Sri Handayani Bambang Supriatno Bebena, Ismiralda Budiyanto, Darmawan Cahyadi, Lalu M. Zidan Dadi Setiadi Debora Turnip, Lowisa Deddy Hartanto Delphi, Syakila Gita Diah Lestari, Diah Didik Santoso Dyah R Hizbaron, Dyah R E. Devi Dwi Rianti, E. Devi Dwi Edi Ariyanto Fadhillah, Falya Aura Farida Agustin, Farida Farnia Sari, Farnia Fauzi, Hairul Febiyanto, Novian Gaya Tridinanti, Gaya Gunawan, Nofri Hakim, Muhammad Alfianul Hakim, Muhammad Nur Haliza, Eva Nur HANDRA, HEFRIZAL Helena, Shifa Herietrenggi, Kristanti Herman, Marliah Ananda Hery Kresnadi I Wayan Mertha Ilhamdi, M Liwa Ilmi, Muhamad Yazid Mizanul Istiqomah, Nurul Hafifah Jamilul Insan Jamí’’yyah, Shafro’Khuluq Kasnadi, Kasnadi Kausar, Shakila Ketut Rachmi Handayani , I Gusti Ayu Khaerunnissa, Intan Kurniawan, Ganesa Puput Dinda Kusuma, Anindita Suliya Hangesti Mandra Lestari, Septiani Lestari, Tri Ayu Lunga, Fransisca Novita Lutfiani, Salsabila Arzaqia M. Guntur Hamzah M. Shoffa Saifillah Al Faruq Maryatul Qiptiyah Mas Mansyur, Mas Mawati, Nenni Mohamad Rahmad Suhartanto Mohd Arifullah Muhammad Yusup Musli musli Nabila, Hesti Ni Luh Putu Pebri Artayani . Niarni, Baiq Gina Amalia Nijam Akbar, Muhammad Nita Ria, Nita Nora Idiawati Nugroho, Rahmad Nur, M. Faidotun Nuryana, Muhammad Insyirah Rizieq Octaviani, Azzya Pambudi, Restu Arya Pasaribu, Merci Monica Prasetyorini, Tri PUJI LESTARI Putri, Hermaya Sura Putri, Siska Aulia Rasmi, Dewa Ayu Citra Razzaq, Agung Abdul Reza Faizal, Reza Riandi Riandi Ridho, M.Rasyid Ririen Wardiani, Ririen Ristianafi, Diana Putri Ropidah, Risky Riyyatul Saifillah al-Faruq, Muhammad Sofa Sakaroni, Rubiyatna Sapta R , Fajria Noor Sastro, Marlia Seftiana, Irma Semendawai, Muhammad Yusuf Sesareny, Nadiya Setiyono, Tatang Solly Aryza Sri Hartati Sur’atunisa, Dean Sutejo Sutejo SUYANTRI, ENI Syaharuddin Y, Syaharuddin Y Syamsul Bahri Syarif, Algifari Tahmid Sabri Tangkudung, James Tegnan , Hilaire Tipa, Kurniayati Uswatun Hasanah Utami, Ulya Febria Venna, Venna Wahyuningtyas Puspitorini Warada, Hafindro Wisesa, Adinda Bonita Wiwi Isnaeni Wyrmand, Dustin Zuanisa, Ai Zulfan