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All Journal JURNAL GIZI INDONESIA Jurnal Ilmu Kedokteran (Journal of Medical Science) Majalah Kedokteran Bandung Medical Journal of Indonesia Jurnal Kesehatan Andalas Jurnal Penelitian Sains Jurnal Kesehatan Manarang Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Journal of Midwifery Jurnal Respirologi Indonesia Majalah Kedokteran Andalas International Islamic Medical Journal Narra J Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah Jurnal Sains, Teknologi dan Kesehatan
Aisyah Elliyanti
1) Nuclear Medicine Division Of Radiology Department, Faculty Of Medicine, Universitas Andalas, Padang, Indonesia 2) Dr. M. Djamil Hospital, Padang, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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PEMERIKSAAN DAN PENGOBATAN MATA DAN KULIT PADA KELOMPOK LANSIA DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Rina Gustia; Hendriati Hendriati; Zelly Dia Rofinda; Yulistini Yulistini; Afriwardi Afriwardi; Elmatris Sy
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 2 No. 1 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v2i1.97

Abstract

Health services for the elderly need to get special attention, because they are vulnerable for suffering from disease and tend to experience multi-pathology. Some of the health problems of the elderly in Kenagarian Sumaniak had been identified in community service activities before. Aim: The activity aims is to conduct examination and treatment of eye and skin disorders, as also to conduct counseling on the elderly. Methods: The activity is ayes and skin examination and treatment for elderly people in Kenagarian Sumaniak. Furthermore, counseling was also given regarding physical fitness and maintenance of skin health in the elderly. Results: The event was attended by 70 people aged 52-82 years, 28 men and 52 women. The results of the examination found 64 people suffering from eye disorders with diagnoses were dry eyes 24person, immature cataract 16 person and pterygium14 person. Around 52 people suffering from skin disorders with diagnoses were dermatitis 28 person such as dermatitis allergy, numularis, intertriginosa, sebaroid, and chronic). Conclusions: Health problems in the eyes and skin of the elderly identified are mostly overcome with the medicines provided. Some of them are recommended to go to primary health care to get further health services.
PEMERIKSAAN BUTA WARNA, GOLONGAN DARAH DAN KADAR HEMOGLOBIN PADA ANAK USIA SEKOLAH DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Zelly Dia Rofinda; Hendriati Hendriati; Julizar Julizar; Rahmat Syawqi; Husnil Wardiyah
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 3 No. 2 (2020)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v3i2.199

Abstract

The growth and development of children disturbance is a health problem that often is found in the community. Anemia and colour blindness are also health conditions that can affect the quality of growth and development of children, which parents rarely realize. The blood type of children is seldom defined in early ages by the parents. This activity aims to conduct health counselling, the examination of colour blindness, blood type, and hemoglobin levels in school-age children in Sumanik village. Methods: Activities were health education on how to wash hands properly and be aware of internet content. The activities were continued by a health examination, such as examining colour blindness, hemoglobin levels, and blood type. Testing of blood type on 76 children, two of 79 children has partial colour blindness. We found From 28 children (36.4%) having anemia, with hemoglobin levels 9.2-11.9 gr / dL, and one child has a blood type B rhesus (-). From this activity, it can be concluded that the low level of knowledge of school-age children in Kenagarian Sumaniak about how to wash hands properly and correctly, even children do not know the adverse effects associated with adult content on the internet. In addition, it appears that children with anemia are still relatively high. For this reason, continuous health promotion is needed. For disorders that can not be overcome at the time of activity, it is recommended to get treatment to the nearest health care centre.
MITIGASI DAN EVAKUASI BENCANA PADA MASA PANDEMI COVID-19 BAGI MASYARAKAT PASIE NAN TIGO KOTO TANGAH KOTA PADANG Aisyah Elliyanti; Julizar Julizar; Lili Irawati; Miftah Irrahmah; Afriwardi Afriwardi; Yose Ramda Ilhami; Fika Anggraini; Rahmad Syawqi
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 5 No. 4 (2022)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v5i4.333

Abstract

Disaster events both natural and non-natural factors such as epidemics can occur anytime and anywhere, which can affect communities and individuals. This natural or human-caused event or series of events can result in human casualties and suffering. Losses caused by disasters can be minimized or prevented if people's understanding of the disaster itself is sufficient, especially during the Covid-19 pandemic. Purpose: This activity is to conduct disaster mitigation training in the conditions of the Covid-19 pandemic for teachers at the Kanzul Ulum Islamic Boarding School, Kelurahan, in Pasie Nan Tigo, Koto Tangah District, Padang City. Activity target: the people of Pasie Nan Tigi Koto are able to carry out disaster mitigation and evacuation in the event of an earthquake followed by a tsunami, rising sea levels and waves. Method: activities in the form of lectures and exercises that begin with the distribution of masks to all participants involved in the activity, and filling out questionnaires on Covid-19 prevention and disaster management. After delivering the material, it was followed by a discussion on Covid-19 prevention, as well as drills on disaster mitigation and victim evacuation. The results of the activity were an increase in disaster mitigation and evacuation capabilities as well as an increase in participants' awareness in implementing health protocols for the prevention of Covid-19. Most of the participants' understanding of Covid-19 prevention and disaster management had increased, as evidenced by the increase in the number of correct questionnaire answers during the post-test compared to the pre-test from 50% to 80%. In addition, participants' skills have also increased regarding disaster mitigation, the implementation of evacuation techniques when a disaster occurs and how to evacuate victims when the disaster has subsided. Conclusion: Every individual left behind in a disaster-prone area needs to receive knowledge and training skills in disaster mitigation and evacuation techniques during the Covid-19 pandemic.
FAKTOR-FAKTOR YANG MEMPENGARUHI SURVIVAL RATES PASIEN YANG MENDAPATKAN  RADIOTERAPI PADA KANKER OVARIUM : SYSTEMATIC REVIEW Genia, Dara Indah; Ariani, Novita; Suharti, Netti; Syamel, Muhammad; Elliyanti, Aisyah; Intan, Shinta Ayu
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 2 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i2.1266

Abstract

Ovarian cancer is known as a silent but deadly disease (silent killer) so it is not uncommon for sufferers to end in death. Radiotherapy for ovarian cancer is indicated as adjuvant therapy for advanced stages in an effort to extend survival rate. This review aims to determine the factors that influence survival rates, local control, and toxicity leves in patients receiving radiotherapy for ovarian cancer. This research is a narrative reviw using the PRISMA method. A literature search was conducted in three databases Pubmed, CENTRAL and Science Direct in the 2013-2023 period. The specified keywords are adapted to the terms Medical Subject Headings (MeSH) and research questions using the PEO formula. Articles were selected based on predetermined inclusion and exclusion criteria. There are 9 selected primary articles and included in the narrative reflection. As many as 3 out of 9 studies stated first-line therapy in the form of total debulking surgery of lesions treated before RT as a factor that significantly influenced survival rates, 2 studies stated CA-125 levels before and after RT had a significant effect on survival rates, 2 studies explained that patients with platinum sensitivity and CCC histological subtypes had better survival rates, and 2 other literatures explained that cancer stage at diagnosis, cancer volume, and post-treatment or not after RT also significantly affected survival rates. Ovarian cancer patients who undergo radiotherapy have better survival rate than patients who do not receive radiotherapy with excellent local control and limited radiation related toxicity that is relatively well tolerated by patients
Exploring the potential effects of Lactococcus lactis D4 on the proliferation, apoptosis, and inflammatory responses in colorectal cancer cells Rivai, Muhammad I.; Lusikooy, Ronald E.; Putra, Andani E.; Elliyanti, Aisyah; Sukma, Ade
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1596

Abstract

Lactococcus lactis D4 is a probiotic produced through the fermentation of buffalo milk in bamboo, namely "dadih", a traditional food from West Sumatera, Indonesia. To the best of our knowledge, no specific research has investigated the effects of L. lactis D4, derived from dadih extraction, on colorectal cancer or its potential clinical applications. Therefore, the aim of this study was to evaluate the potential of L. lactis D4 from dadih to inhibit colorectal cancer growth in rat models, with a focus on its effects on cell proliferation, apoptosis, and inflammatory responses. An in vivo study was conducted using 37 male Sprague-Dawley rats, allocated into five groups: (1) control (no treatment), (2) dysplasia (induced with 1,2-dimethylhydrazine until dysplasia developed), (3) dysplasia + L. lactis D4 (induced with 1,2-dimethylhydrazine, then treated with L. lactis D4 after dysplasia confirmation), (4) cancer (induced with 1,2-dimethylhydrazine until cancer was confirmed), and (5) cancer + L. lactis D4 (induced with 1,2-dimethylhydrazine until cancer was confirmed, then treated with L. lactis D4 for 15 days). The effects of L. lactis D4 on cancer progression were assessed through immunohistochemical analysis of cell proliferation (cyclin D1, Bcl-2), apoptosis (p53, caspase-3), and inflammation (nuclear factor-κB (NF-κB) and cyclooxygenase-2 (COX-2)). This study found that L. lactis D4 treatment reduced adenocarcinoma and dysplasia severity in colorectal cancer models through significant reduction in cyclin D1, Bcl-2, NF-κB, and COX-2 expression observed across all groups (p<0.01), although changes in dysplasia and cancer subgroups were not statistically significant (p>0.05). No statistically significant change was noted in p53 expression (p=0.518), whereas caspase-3 expression varied significantly across groups (p=0.010). In conclusion, L. lactis D4 reduces the expression of cyclin D1, Bcl-2, NF-κB, and COX-2 proteins, offering insights into its potential to modulating proliferation and inflammation in colorectal cancer growth.
Mortality and associated factors among community-acquired pneumonia patients: A cross-sectional study in a provincial referral hospital in Indonesia Rosdiana, Dani; Siregar, Fajri M.; Ediwi, Nabila C.; Putri, Rahmi T.; Nurrahma, Zuyyina ER.; Elisabet, Adinda; Sarassari, Rosantia; Safari, Dodi; Ilmiawati, Cimi; Elliyanti, Aisyah
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1649

Abstract

Community-acquired pneumonia (CAP) poses a significant impact on the healthcare system due to rehospitalization and mortality. About one-third of hospitalized CAP patients died within one year. In addition to advanced age, vulnerable groups with comorbidities such as cancer, diabetes, and cerebrovascular disease (CVD) are more likely to suffer from severe CAP. The aim of this study was to investigate the factors linked to mortality in adult hospitalized CAP patients. The study extracted the medical records of patients aged ≥18 years, admitted to a referral hospital in Riau Province, who were diagnosed with CAP between January and December 2023. Multiple logistic regression step-wise analysis was employed to determine the factors associated with mortality in CAP patients. The study involved 334 patients with a median age of 58 years. Based on the confusion, urea, respiratory rate, blood pressure, and age ≥65 years (CURB-65) score, 11.9% of patients had severe CAP (CURB-65 scores 3 and 4). Age was a significant predictor of severe CAP (p≤0.001). The most prevalent comorbidities were malignancy (33.2%), CVD (30.2%), and diabetes (28.4%). Mortality incidence during hospitalization reached 35.9%. Significant factors associated with mortality in hospitalized CAP patients included renal dysfunction/elevated serum urea levels (p=0.031), CURB-65 score (p=0.023), vasopressor use (p≤0.001), mechanical ventilator use (p≤0.01) and steroid use (p=0.029). However, CVD was associated with a decreased risk of mortality (p=0.019). Gram-negative bacteria predominated, accounting for 50.6% of all positive isolates.  Several significant factors were associated with mortality in adult patients hospitalized with CAP at referral Hospital in Riau, including renal dysfunction, CURB-65 score, vasopressor use, mechanical ventilator use, and steroid use. This finding underscored the importance of early identification factors in CAP patients.
Analisis Ekspresi Protein c-Fos pada Cell Line Kanker Payudara Elliyanti, Aisyah
Majalah Kedokteran Andalas Vol. 48 No. 1 (2025): MKA January 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i1.p1-12.2025

Abstract

Tujuan: Untuk menganalisis ekspresi protein c-Fos pada cell line kanker payudara. Metode: Penelitian ini merupakan penelitian eksperimental murni menggunakan metode imunositofluoresens untuk melihat jumlah intensitas ekspresi protein c-Fos dengan sampel penelitian adalah cell line MCF-7 mewakili kanker payudara subtipe luminal A, cell line SKBR3 mewakili kanker payudara subtipe HER2+, dan cell line HaCat mewakili sel normal. Ekspresi protein c-Fos diinduksi dengan EGF 50 ng/mL, ATP 100µM dan gabungan ATP+EGF selama 45 menit. Perhitungan intensitas protein c-Fos menggunakan aplikasi imageJ. Hasil penelitian ekspresi c-Fos dianalisis menggunakan uji oneway anova  apabila p<0.05 dianggap berbeda secara signifikan. Hasil: Ekspresi protein c-Fos pada cell line yang diberi perlakuan ATP dan EGF meningkat dibandingkan kontrol. Peningkatan intensitas protein c-Fos terdapat pada ketiga jenis cell line. Tidak terdapat perbedaan bermakna pada ketiga jenis sel berdasarkan jenis induksi (p>0,05). Kesimpulan: Pemberian ATP, EGF dan kombinasi ATP+EGF meningkatkan intensitas protein c-Fos pada cell line kanker payudara tipe MCF-7 dan SKBR3.
Pengaruh pemberian Iodine-131 terhadap viabilitas cell line Triple Negative Breast Cancer (TNBC) Monika, Katrin; Elliyanti, Aisyah; Kurniawati, Yulia
Majalah Kedokteran Andalas Vol. 46 No. 4 (2023): Online Oktober
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i6.p912-918.2023

Abstract

AbstractObjective: To determine the effect of Iodine-131 administration on the viability of triple negative breast cancer cell lines and the IC50 value of Iodine-131. Methods: This study was a true experimental study using the MTT assay method to measure cell line viability after being given Iodine-131 at a dose of 7.8; 15.6; 31.3; 62.5; 125; 250; and 500 µCi for 24 hours. The research sample was the MDA-MB231 cell line which represents the Triple Negative Breast Cancer (TNBC) subtype of breast cancer. The IC50 value of Iodine-131 cell line MDA-MB231 was calculated using the GraphPad Prism-9 software. The results were analyzed using the Kruskal-Wallis and Post-Hoc Kruskal-Wallis tests, if p <0.05 was considered to significantly affect cell viability. Results: Iodine-131 affected cell viability in the MDA-MB231 cell line with a p<0.05. The IC50 value of Iodine-131 on the MDA-MB231 cell line was 255.7 µCi. Conclusion: Administration of Iodine-131 at a dose of 500 µCi for 24 hours significantly reduced the viability of the MDA-MB231 cell line. Iodine-131 dose of 255.7 µCi can inhibit 50% viability of the MDA-MB231 cell line.Keywords: Iodine-131; cell viability; cell line MDA-MB231; TNBC; IC50
The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia Febrianti, Ika Kurnia; Putra, Andani Eka; Raveinal, Raveinal; Elliyanti, Aisyah
Majalah Kedokteran Andalas Vol. 47 No. 2 (2024): MKA April 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v47.i2.p139-147.2024

Abstract

Objective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records including demographic data, and laboratory results such as hemoglobin, hematocrit, leukocytes, platelets, coagulation markers (D-dimer, PT, and APTT), and patients outcomes post-treatment. Statistical analysis is performed by using chi-square and Mann-Whitney tests were considered statistically difference level of significant between variables. Result: The COVID-19 patients is classified into mild group with 27 subjects  (44.2%) and moderate-severe group 34 subjects (55.8%). Leukocytes, D-dimer, and PT levels significantly differed between mild and moderate-severe groups. All coagulation markers had a symptomatic effect on Covid-19 patients, increased D-dimer and prolonged prothrombin time in adult COVID-19 patients tend to be followed by the enhancement of severe symptoms and death
The Potential of Iodine as A Treatment for Breast Cancer: A Narrative Review Ibrahim, Raihan Syah; Elliyanti, Aisyah
Jurnal Kesehatan Manarang Vol 9 No 3 (2023): December 2023
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v9i3.834

Abstract

Breast cancer is a cancer with the highest incidence of death in women in the world. Studies state that breast cancer can capture iodine molecules, making this substance a potential alternative therapy for further research and study. Opportunities for iodine as a treatment for breast cancer are supported by the fact that iodine is a molecular element widely available in nature, such as in food, plants, and oceans, so iodine is an easy substance to obtain. This article explores the potential of iodine as a treatment for breast cancer. The method used is a literature review study, in which literature is collected through the PubMed, Science Direct, and Google Scholar databases published from 2013-2022, and full text is available. The results of the review of the 10 articles obtained are the exposure of sources and intake of iodine, the physiological effects of iodine, and the effects of iodine on breast cancer cells. Iodine has the potential as a substance with anticancer activity through antiproliferative mechanisms, apoptosis, and immune system activation when given in sufficient quantities and at appropriate doses. The mechanism of iodine affecting breast cancer cells occurs through direct and indirect effects on the biological processes of cancer cells. These mechanisms occur molecularly in cancer cells by intermediary mitochondrial organelles and specific ligands in the cell. Iodine can also be combined with breast cancer chemotherapy, such as doxorubicin, which gives a good treatment response after chemotherapy. This is important to ensure sufficient daily intake of iodine for the body, especially in patients with breast cancer.
Co-Authors Ade Sukma Afriwardi Afriwardi Andani Eka Putra Angriani, Winda Ariani, Novita Arina Widya Murni Arnelis Arnelis Arni Amir Ashal, Taufik Aswiyanti Asri Aziza, Zulva Cimi Ilmiawati, Cimi Daan Khambri Dani Rosdiana Desmawati Desmawati Dewi Anggraini Dewi Anggraini Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Ediwi, Nabila C. Elisabet, Adinda Elizabeth Bahar Elmatris Sy Eryati Darwin Esha, Indi Eti Yerizel Faiz Chalidzar Fasril , Thira Febrianti, Ika K. Febrianti, Ika Kurnia Fika Anggraini Fika Anggraini Fitri Wahyu Febriwani Genia, Dara Indah Hafizhah, Nurul Hanifah, Zulfa N. hanifah, zulfa nur Harahap, Sari Hendriati, Hendriati Herlambang Herlambang Husna Yetti Husna, Annisaul Husnil Wardiyah Ibrahim, Raihan Syah Ika Kurnia Febrianti Ilmiati Ilmiati INDRA YOVI Intan, Shinta Ayu Irrahmah, Miftah Iskandar Iskandar Johan S. Masjhur, Johan S. Julizar Julizar Julizar Julizar Julizar Julizar Katrin Monika Lili Irawati Lili Irawati Lusikooy, Ronald E. Mardhatilah, Ashifa Meidrin Joni Miftah Irrahmah Miftah Irrahmah Miftah Irramah Mohamad Reza Monika, Katrin Netti Suharti, Netti Noormartany Nora Harminarti Noza Hilbertina, Noza Nur Afrainin Syah Nurhajjah, Sitti Nurrahma, Zuyyina ER. Putra, Andani E. Putri, Nabila Putri, Rahmi T. Raden Mohamad Herdian Bhakti Rahmad Syawqi Rahmad Syawqi Rahman, Fikri Rahmat Syawqi Rahmat Syawqi Raihan Syah Ibrahim Ramacos Fardela Rasya, Salsabila Faiha Wiendra Rasyada, Latifah Aulia RAVEINAL RAVEINAL Rina Gustia Rivai, Muhammad I. S Setiyowati Sabar Hutabarat Safari, Dodi Safitri, Nuridha Audinia Salsabila, Dhianisa Sarassari, Rosantia Shapira, Vanesya Zahrani Simanjuntak, Arya M. Siregar, Fajri M. Siregar, Muhammad Abi Ghoffari Siti Nurhajjah Sorayya A'dilah Putri Sri Setiyowati Suminta RS, Teresia Susilo, Veronica Y. Syah, Nur A. Syaiful Azmi Syamel, Muhammad Tenny Putri Wikayani, Tenny Putri Tofrizal, Alimuddin Tri Hanggono Achmad Veronica, R. Merlinda VY Susilo Wulandari Wulandari Yose Ramda Ilhami Yose Ramda Ilhsmi Yulia Iriani, Yulia Yulia Kurniawati Yulia Kurniawati Yulistini, Yulistini Yusticia Katar, Yusticia Zelly Dia Rofinda