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All Journal VALENSI Alchemy : Journal of Chemistry EduChemia: Jurnal Kimia dan Pendidikan Jurnal Zarah AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Jurnal Penelitian Pendidikan IPA (JPPIPA) Insect (Informatics and Security) : Jurnal Teknik Informatika JURNAL PENDIDIKAN TAMBUSAI Jurnal Kartika Kimia Jurnal Pengabdian Magister Pendidikan IPA Jurnal Pensil : Pendidikan Teknik Sipil FITOFARMAKA: Jurnal Ilmiah Farmasi JURNAL BIOSAINSTEK MATHEMA: JURNAL PENDIDIKAN MATEMATIKA Neraca Journal of Technomaterial Physics Jurnal Difusi Mamba'ul 'Ulum Helium: Journal of Science and Applied Chemistry SENTRI: Jurnal Riset Ilmiah Jurnal AKAL: Abdimas dan Kearifan Lokal Jurnal Pemberdayaan Masyarakat Venn: Journal of Sustainable Innovation on Education, Mathematics and Natural Sciences Journal Economics Technology and Entrepreneur AL HAZIQ: Journal of Community Service Pawarta: Journal of Communication and Da'wah Indonesian Journal of Law and Justice Jurnal Teknik Sipil LATERAL Jurnal Pengabdian Masyarakat dan Riset Pendidikan RESLAJ: Religion Education Social Laa Roiba Journal Journal of Internet and Software Engineering Izzatuna: Jurnal Ilmu Al-Qur'an dan Tafsir Celebes Journal of Community Services KAMBIK : Journal of Mathematics Education
Muhammad Fathurrahman
Prodi Kimia FMIPA Universitas Pakuan
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Transportation Other

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Tinjauan Pustaka: Inovasi Formulasi Tablet Lepas Lambat Untuk Meningkatkan Kepatuhan Pasien Mulia, Reski; Fathurrahman, Muhammad
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 12 (2025): SENTRI : Jurnal Riset Ilmiah, Desember 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i12.5147

Abstract

Patient adherence to medication regimens is a crucial determinant of therapeutic success. Poor adherence remains one of the major causes of treatment failure, particularly in long-term therapies that require consistent and repeated drug administration. One effective pharmaceutical strategy to enhance patient compliance is the development of sustained-release drug delivery systems. These systems are designed to release active pharmaceutical ingredients gradually over an extended period, thereby maintaining therapeutic drug concentrations in the bloodstream while reducing dosing frequency. This systematic review aims to analyze recent innovations in sustained-release tablet formulations developed over the past decade and to evaluate their contribution to improving patient adherence. Literature searches were conducted across major scientific databases, including PubMed, ScienceDirect, and Google Scholar, covering publications from 2015 to 2025. The search employed the following keywords: “sustained release tablet,” “controlled release formulation,” “patient compliance,” and “pharmaceutical innovation.” A total of 32 articles met the inclusion criteria after rigorous screening and evaluation. The analysis revealed substantial advancements in formulation technology, particularly through the application of both natural and synthetic polymers such as hydroxypropyl methylcellulose (HPMC), carbopol, and chitosan. Furthermore, the integration of modern technologies—including 3D printing, matrix systems, and osmotic pump mechanisms—has significantly enhanced drug release efficiency, prolonged therapeutic duration, and minimized dosing frequency. Overall, sustained-release tablet formulations play a pivotal role in improving patient adherence, especially in chronic treatments, and continue to evolve alongside modern pharmaceutical innovations.
Sistematik Review: Jenis-jenis Gen yang Berpengaruh terhadap Penurunan Kadar Gula Darah pada Pasien Diabetes Melitus Tipe 2 Fathurrahman, Muhammad; Mulia, Reski
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 12 (2025): SENTRI : Jurnal Riset Ilmiah, Desember 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i12.5148

Abstract

Blood glucose reduction in patients with type 2 diabetes mellitus (T2DM) varies considerably among individuals, largely due to genetic factors that influence responses to antidiabetic drug therapy. This interindividual variability affects both the effectiveness and safety of commonly prescribed oral antidiabetic agents. Therefore, understanding the genetic determinants of treatment response is essential for optimizing glycemic control in patients with T2DM. This systematic review aims to identify genetic polymorphisms associated with variations in blood glucose reduction, particularly in patients receiving metformin, sulfonylureas, and other oral antidiabetic drugs. A comprehensive literature search was conducted using the PubMed, Scopus, and Google Scholar databases. A total of 880 articles were initially identified, of which 760 articles passed the preliminary screening based on title and abstract relevance. Following full-text screening using predefined inclusion and exclusion criteria, five studies were deemed eligible and included in the final analysis. The findings indicate that several genes play a major role in determining glycemic response to oral antidiabetic therapy, including SLC22A1 (OCT1), SLC22A2 (OCT2), SLC47A1 (MATE1), CYP2C9, KCNJ11, ABCC8, and TCF7L2. Genetic variations in these genes influence drug pharmacokinetics and pharmacodynamics, thereby contributing to differences in therapeutic effectiveness and glycemic outcomes among patients.
MENGUNGKAP MEKANISME SOSIAL DI BALIK STUNTING: STUDI KUALITATIF TENTANG KEMISKINAN STRUKTURAL, BUDAYA KONSUMSI, DAN PENGASUHAN LINTAS GENERASI DI DESA CIAMBAR, SUKABUMI Nurhayati, Nurhayati; Fathurrahman, Muhammad; Haulian Sirait, Koramen; Laksmi Subadra, Ni Putu Ayu
Journal Economics Technology And Entrepreneur Vol 4 No 04 (2025): ECOTECHNOPRENEUR : JOURNAL ECONOMICS, TECHNOLOGY AND ENTREPRENEUR
Publisher : Pusat Studi Ekonomi, Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/ecotechnopreneur.v4i04.2087

Abstract

This study aims to understand how socio-economic conditions, food consumption patterns, intergenerational childcare practices, environmental sanitation, and access to integrated health posts (Posyandu) interact to shape stunting risk among children under five. An intrinsic case study design with a qualitative approach was employed. Thirteen informants—comprising parents, two Posyandu cadres, and the village head were purposively selected. Data were collected through in-depth interviews, participant observation, and document review, then analyzed thematically using NVivo 12. Findings reveal that unstable income, a "just full enough" consumption orientation, caregiving by grandmothers with limited nutrition literacy, inadequate sanitation,& irr egular Posyandu utilization collectively form social mechanisms that incr ease stunting risk. Word frequency analysis identified "Alhamdulillah" as a cultural coping mechanism that normalizes food insecurity. The study concludes that addressing stunting requires multi-level, family- and community-based interventions integrating food security, nutrition educa tion, sanitation improvement, and strengthened Posyandu functions.
Effectiveness of The Team Games Tournament (TGT) Learning Model Using Wordwall on Mathematics Learning Outcomes on Plane Shapes at Smp Negeri 9 Kota Sorong Falni, Falni; Musa’ad, Faida; Rusani, Irna; Fathurrahman, Muhammad; Trisnawati, Nika Fetria; Fernayanan, Riyanti; Djoroho, Theresia G
Venn: Journal of Sustainable Innovation on Education, Mathematics and Natural Sciences Vol. 4 No. 3 (2025): Matematika, IPA, dan Pembelajarannya
Publisher : Pusat Studi Bahasa dan Publikasi Ilmiah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53696/venn.v4i3.378

Abstract

This study aims to determine the effect of the Team Games Tournament (TGT) learning model assisted by a word wall on the mathematics learning outcomes of eighth-grade students at SMP Negeri 9, Sorong City. The method used was a pre-experimental one with a One Group Pretest-Posttest design. The sample consisted of 25 students, and the research instruments in the form of pretest and posttest. Data analysis used the Shapiro-Wilk test, the Wilcoxon Signed Ranks Test, and the N-Gain test. The results showed a significant difference between pretest and posttest scores (p = 0.000 < 0.05) and an average N-Gain of 0.63 (moderate category). Learning with TGT assisted by a word wall has been proven to effectively improve students' conceptual understanding and learning motivation
Co-Authors . Apriansyah Ade Heri Mulyati, Ade Heri Agus, Muhammad Abduh Akram Agustino Zulys Ahmad Jupri Ahmad, Afifah Anwari Mattali Al Husnah, Miftah Alfauzi, Ikhsanurdien Alhasbi, Faruq Anna Permanasari Anwar, Najih Arif Darmawan Aryati, Ida Awanda, Misuki Ayu Lestari, Putri Baidhowi Billah, Salsa Destiyana, Stevany Dewanto, Muhammad Arif Bagus Didik Hariyanto Djoroho, Theresia G Dwinanto, Irwin Dwiyana, Amelia Eka Herlina Fahrurrozi, F Falni, Falni Fatmawati, Nur Aisyah Fauzi, Zaini Fauziah, Zahra Nur Fernayanan, Riyanti Firdaus, Danar Restu Firdaus, Muhamad Iqbal Ansori Fredy Jhon Philip Sitorus Gayatri, Baiq Alon Pramudhya Ghofar, Abd Hanifah, Aniqah Hanum, Siti Zaida Hendiyani, Rani Henny Purwaningsih Hudaya, Fadli Hudaya Ibad, Taqwa Nur Irianti, Septi Ismail Djakaria Jannah, Eka Yuni Nur Jannatun, Baiq Haulia Jarnuzi Gunlazuardi Java, Abyanuddin Al Jeki Purnama Putra Kabir, Abyan Jausan Kahar, Muhammad Syahrul Koramen Haulian Sirait Kurniawan, Reggiene La Aba Laksmi Subadra, Ni Putu Ayu Leny Heliawati Linda Jati Kusumawardani Liswara, Musa Ahmad M. Zainuddin Maharani, Restu Dewinta Manalu, Keren Mardiman Mardiman, Mardiman Maulani, Mustamina Maulida, Khoviva Megan, Aspasia Asprila Mimin Kusmiyati, Mimin Mirna Ari Mulyani Misdalena, Felly Mufasiroh, Hanif Fika MUHAMMAD ALI Muhammad Fachmi MUHAMMAD TAUFIK Mulia, Reski Mursito, Bambang Musa’ad, Faida Neliwati Noer, Zikri Nugraha, Yoga Nuraeni, Verlita Nurhayati Nurhayati NURUL HIDAYAH Patricia, Cicilia Benita Putri Permanasari, Arlina Puji Astuti Purwantiningsih Sugita Putra, Bela Janare Putri, Nabila Amalia Rahmatullah Bin Arsyad Rahmawati, Miftah Sigit Rasiwan, Iwan Rohmawati, Indi Rozi, Tapaul Rusani, Irna Saebani Saebani, Saebani Saleha, Isma Muslihati Salsabila, Filzah Maharani Sangadji, Zulkarnain Saputra, Ranu Arya Sarawa, Sarawa Sarira, Regina Amelia Setiawan, Aep Siahaan, Lolo Ferdinan Siregar, Annisa Novita Putri Siti Fatimah Subando, Joko - Sujendra, Ida Bagus Alit Sukresna, Yobi Suparman Suswandari Sutanto Sutanto Suwanta, Deni Maulana Syahrial, Agan Syahril Alzahri, Syahril Tasa, Tyan Taufik Taufik Teguh Hidayat Iskandar Alam Tri Aminingsih Trisnawati, Nika Fetria Uge, Sarnely Ulfah, Yetty Faridatul Umala, Moh usep suhendar Usep Suhendar Virasanty Muslimah Widoyo, Agus Fatuh Wiryan, Lalu Wiwi Siswaningsih Yules Pramona Zulkarnain Yulian Syahputri Zulfiani, Rena