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EPIDEMIOLOGI DAN FAKTOR RISIKO PENYAKIT ARTERI PERIFER: TINJAUAN DARI POPULASI GLOBAL DAN ASIA DENGAN PERBANDINGAN PANDUAN KLINIS Melya Susanti
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1651

Abstract

Peripheral artery disease (PAD) is a systemic manifestation of atherosclerosis that significantly contributes to increased morbidity and mortality, and reduced quality of life. Globally, the burden of PAD shows an increasing trend, with the highest prevalence among the elderly, those with diabetes mellitus, hypertension, dyslipidemia, and those with smoking habits. Global Burden of Disease data demonstrates regional variations in distribution, with Asia displaying distinct sociodemographic determinants and diagnostic challenges. In countries like Indonesia, limited epidemiological data and high underdiagnosis rates remain major barriers to early detection. In addition to the main risk factors, a number of new determinants, including nutritional and lifestyle patterns, exposure to air pollution, chronic inflammation, and genetic predisposition, further exacerbate the disease course. Severe complications, particularly limb-threatening ischemia, are closely associated with coronary artery and cerebrovascular disease, ultimately worsening clinical outcomes in patients with polyvascular disease. This study is a literature review examining international and national publications indexed in Scopus, PubMed, and Sinta within the last five years, as well as the latest clinical guidelines (ESC 2024, ACC/AHA 2024, ESVS 2024). Literature selection was based on relevance to epidemiology, risk factors, clinical implications, and comparability of PAD management guidelines. Global strategies for PAD management generally demonstrate uniformity, although approaches differ in specific populations. Research gaps include limited data in Southeast Asia and a lack of genetic studies in non-European populations. Adapting international guidelines to the local context is essential to more effectively reduce the burden of PAD in the Asian region.
HUBUNGAN BURNOUT DENGAN KUALITAS TIDUR MAHASISWA TINGKAT AKHIR FAKULTAS KEDOKTERAN UNIVERSITAS BAITURRAHMAH Intan Sesri Winarni; Melya Susanti; Revivo Rinda Pratama
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1632

Abstract

Final-year medical students are often exposed to substantial academic demands, the obligation to complete a thesis, and the transition to professional practice. These conditions may trigger burnout, characterized by physical and psychological exhaustion resulting from chronic stress. Burnout can affect multiple aspects of life, particularly sleep quality, which plays a crucial role in maintaining cognitive function, physical health, and psychological well-being. This study aimed to evaluate the association between burnout and sleep quality among final-year medical students at the Faculty of Medicine, Universitas Baiturrahmah. An analytical observational study with a cross-sectional design was conducted. Primary data were collected from 55 respondents using questionnaires. Univariate analysis was presented in frequency distributions, while the chi-square test was employed to examine the association between variables. Among the participants, 33 students (60.0%) were identified as experiencing burnout, while poor sleep quality was reported in 41 students (74.5%). Statistical analysis demonstrated a significant association between burnout and sleep quality (p = 0.032; p < 0.05). Burnout is significantly associated with poor sleep quality among final-year medical students. These findings highlight the need for preventive strategies that integrate stress management and interventions targeting sleep quality.
HUBUNGAN STATUS GIZI DENGAN KOMPLIKASI DIABETES MELITUS TIPE 2 DI RUMAH SAKIT ISLAM SITI RAHMAH Pera Siska; Melya Susanti; Ferry Iskandar Kahrisma
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1633

Abstract

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with an increasing prevalence worldwide and is a major contributor to both microvascular and macrovascular complications. Nutritional status, particularly obesity, is considered to play a key role in the pathogenesis of these complications through mechanisms involving insulin resistance, chronic inflammation, and atherogenic dyslipidemia. However, locally based evidence on the association between nutritional status and T2DM complications remains limited. This research to evaluate the relationship between nutritional status, as measured by body mass index (BMI), and the types of T2DM complications among patients hospitalized at RSI Siti Rahmah Padang. This observational analytic study with a cross-sectional design included 65 T2DM patients with complications admitted between 2019 and 2021. Nutritional status was classified according to the WHO Western Pacific Region criteria, while complications were categorized into macroangiopathy, microangiopathy, and combined forms. Data were analyzed using the Kruskal–Wallis test with a significance level of p<0.05. Most patients were classified as having normal nutritional status (33.8%), followed by class I obesity (26.2%) and overweight (24.6%). Macroangiopathy was the most common complication (50.8%), followed by microangiopathy (46.2%) and combined complications (3.1%). Statistical analysis showed no significant association between nutritional status and the types of complications (p=0.052). BMI-based nutritional status was not significantly associated with the types of T2DM complications. Central adiposity indicators, such as waist circumference, may provide a more accurate measure of risk. Further studies with larger sample sizes are recommended.
HUBUNGAN FAKTOR-FAKTOR YANG MEMPENGARUHI TINGKAT KEPATUHAN IBU TERHADAP PEMBERIAN IMUNISASI DASAR PADABAYI DI PUSKESMAS ANDALAS Safara Innas; Melya Susanti; Mashdarul Ma’arif
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1634

Abstract

Immunization is one of the most effective and efficient public health strategies for preventing various diseases, such as polio, smallpox, tuberculosis, hepatitis B, diphtheria, measles, rubella, CRS, tetanus,pneumonia, and meningitis. However, maternal compliance with immunization is often influenced by several factors, such as lack of knowledge, awareness, timing of immunization, immunization side effects, maternal education, beliefs, and attitudes. This research to determine correlation of factors affecting level of maternal compliance with providing primary immunization of infants at Andalas Health Center. This research is based on pediatric and immunology. The research was conducted in April – December 2024. It uses an unpaired categorical analytic design with 74 respondents selected through consecutive sampling. The data were analyzed univariately in the form of frequency distributions and bivariately using the chi-square test. The characteristics of mothers based on age were mostly 20-35 years as much as 49 person (66,2%), high school education as much as 45 person (60.8%) and employment status is not working as much as 54 person (73.0%). The highest level of compliance was obedient as much as 59 person (79.7%), good knowledge as much as 56 person (75.7%), self efficacy was sure as much as 61 person (82.4%), easy access to services as much as 64 person (86.5%), supportive family support as much as 45 person (60.8%) and supportive health workers as much as 58 person (78,4%). There is a significant correlation between knowledge, education, self efficacy, access to services, family support, health worker support on the level of maternal compliance with primary immunization at the Andalas Health Center with a p-value <0.05. While there is no significant correlation between employment status with p-value 0.493 (>0.05).  There is a correlation between knowledge, education, self-efficacy, access to services, family support, health worker support on the level of maternal compliance with primary immunization.
HUBUNGAN INDEKS MASA TUBUH (IMT) DENGAN KEJADIAN HEMOROID DI BAGIAN BEDAH RSI SITI RAHMAH Ahmad Dzaki; Melya Susanti; Zukhri Zainun
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1635

Abstract

Hemorrhoids are localized dilations of vascular structures caused by the migration or pathological hypertrophy of the pads in the submucosal layer of the lower rectum. In the United States, hemorrhoids are the fourth most common outpatient gastrointestinal diagnosis, accounting for 3.3 million outpatient visits annually. According to Basic Health Research (Riskesdas) data in 2018, approximately 12.5 million Indonesians suffer from hemorrhoidal disease. Factors commonly associated with an increased risk of hemorrhoids include constipation, a low-fiber diet, high body mass index (BMI), pregnancy, and a sedentary lifestyle. This study aims to determine the relationship between body mass index (BMI) and the occurrence of hemorrhoids in the surgical department of RSI Siti Rahmah Padang during the period January 2022 to August 2023. This research employed an observational analytic method with a cross-sectional design. The study sample consisted of patients from the surgical clinic of RSI Siti Rahmah Padang within the specified period who were diagnosed with hemorrhoids, selected using a simple random sampling technique. Data were obtained from the medical records of 166 patients who met the inclusion criteria and were analyzed using the chi-square test. The results showed that the highest incidence of hemorrhoids occurred in adults, with 23 cases (51.1%). Based on gender distribution, females accounted for 27 cases (60%). Regarding BMI, the majority of patients were classified as overweight, with 22 individuals (48.9%) suffering from hemorrhoids. Data analysis demonstrated a significant relationship between BMI and the incidence of hemorrhoids (p = 0.000).
PERSISTENT STAPEDIAL ARTERY SEBAGAI ANOMALI VASKULAR TELINGA TENGAH: SEBUAH TINJAUAN LITERATUR Irwan Triansyah; Nadia Purnama Dewi; Melya Susanti; Ade Teti Vani; Dessy Abdullah
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1645

Abstract

Persistent Stapedial Artery (PSA) is a rare vascular anomaly of the middle ear that results from the failure of the stapedial artery to regress during embryonic development. Despite often being asymptomatic, PSA has significant clinical implications, particularly in middle ear surgery, where it increases the risk of intraoperative bleeding and nerve injury. This review was conducted through a systematic search of PubMed, Scopus, and Google Scholar using the keywords “persistent stapedial artery,” “middle ear,” and “vascular anomaly.” Included articles comprised case reports, case series, and literature reviews from the past 10 years addressing embryology, clinical manifestations, diagnosis, and management of PSA. The findings indicate that PSA can be identified across different age groups, most often incidentally through temporal bone imaging or otologic procedures. In symptomatic cases, clinical features may include pulsatile tinnitus and conductive hearing loss. Temporal bone CT typically demonstrates the absence of the foramen spinosum and the presence of abnormal vascular channels in the tympanic cavity. Management varies, ranging from observation in asymptomatic cases to surgical intervention in patients with symptoms or complications. Although rare, recognition of PSA is critical to prevent intraoperative complications. Further studies are required to clarify the prevalence and define optimal therapeutic strategies. Meanwhile, heightened awareness among otolaryngologists and radiologists can improve diagnostic accuracy and patient safety.
HISTOLOGI PENUAAN KULIT AKIBAT PHOTOAGING: ARTIKEL REVIEW Vani, Ade Teti; Rosmaini, Rosmaini; Nadia Purnama Dewi; Yuliza Birman; Melya Susanti; Rinita Amelia
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1646

Abstract

Photoaging is a complex skin aging process that results from prolonged exposure to ultraviolet (UV) light, leading to notable histological changes. This type of damage can affect both the epidermis and dermis layers of the skin. The purpose of this review article is to highlight and summarize the recent findings from the past five years concerning the histology associated with photoaging and the molecular mechanisms that contribute to this skin damage. The methodology employed involved a thorough literature review of articles published between 2020 and 2025. Journals were identified using targeted keywords, including "photoaging," "skin aging," "histology," and "actinic elastosis." The findings from this search are presented in a narrative format. The study found that UV exposure causes photoaging of the skin with damage to the epidermis and dermis. Photoaging causes structural and functional changes in the skin and causes gene mutations leading to skin carcinogenesis.
PEMANFAATAN TERAPI SHIATSU SEBAGAI TINDAKAN PREVENTIF CEDERA OTOT Nasywa Yudeldi; Ade Teti Vani; Dessy Abdullah; Rosmaini, Rosmaini; Nadia Purnama Dewi; Yuliza Birman; Melya Susanti; Rinita Amelia
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1649

Abstract

Shiatsu therapy is a complementary treatment approach rooted in Japanese tradition, based on the principle of applying pressure to specific points on the body to stimulate energy flow, improve health, and support well-being. This study aims to explore the effect of shiatsu therapy on reducing the risk of injury. This study utilized a qualitative methodology, conducting a literature review of journals published between 2015 and 2025 related to shiatsu therapy. The search employed the keywords "shiatsu massage," "shiatsu for muscle injury," and "effect of shiatsu." Findings from the literature were synthesized and presented in narrative form The findings indicate that shiatsu therapy may reduce the risk of injury by decreasing muscle tension, enhancing flexibility, and increasing range of motion. Furthermore, shiatsu therapy is associated with psychological benefits, including reduced stress and improved sleep quality, both of which are crucial for recovery. Therefore, shiatsu therapy represents a potential strategy for injury prevention and comprehensive health maintenance.
MEKANISME PATOFISIOLOGIS DAN TATA LAKSANA KLINIS PUBERTAS PREKOKS: SEBUAH TINJAUAN TERINTEGRASI Melya Susanti
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1652

Abstract

Precocious Puberty: Etiology, Psychosocial Impact, and Management Puberty is a complex biological process characterized by activation of the hypothalamic–pituitary–gonadal (HPG) axis, resulting in both physical and psychosocial changes. Precocious puberty (PP) is defined as the onset of pubertal signs before the age of 8 years in girls and 9 years in boys. This condition is classified into central precocious puberty (CPP), caused by premature activation of the HPG axis, and peripheral precocious puberty (PPP), which occurs independently of gonadotropin stimulation. Globally, the prevalence of PP has been rising, particularly among girls, with epidemiological studies from Denmark to various Asian countries reporting similar trends. Contributing factors include genetic variations (such as mutations in MKRN3 and DLK1), dysregulation of KNDy neurons, epigenetic mechanisms, obesity, nutritional patterns, exposure to endocrine-disrupting chemicals, and psychosocial stress. The consequences of PP extend beyond accelerated growth and compromised adult height prediction, encompassing psychosocial dimensions such as heightened anxiety, reduced selfesteem, social stigma, and difficulties in academic performance and peer relationships. Early diagnosis and appropriate management—particularly the use of gonadotropin-releasing hormone (GnRH) agonists in CPP—have proven effective in delaying pubertal progression and mitigating long-term sequelae. Given the increasing prevalence, a comprehensive understanding of the etiology, clinical consequences, and management strategies for PP is essential for both clinicians and researchers.
PROFIL FUNGSI KOGNITIF DAN FAKTOR YANG MEMPENGARUHINYA BERDASARKAN KARAKTERISTIK LANSIA DI POSYANDU LANSIA DIKOTO TANGAH Melya Susanti; Rinita Amelia; Prima Adelin; Rahma Triyana
Nusantara Hasana Journal Vol. 3 No. 10 (2024): Nusantara Hasana Journal, March 2024
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v3i10.1118

Abstract

The elderly in the world and in Indonesia continue to increase. According to WHO, the number of elderly people worldwide is currently estimated at more than 629 million people, and by 2025 the elderly will reach 1.2 billion. Aging is a process when humans experience a gradual decline in physical/biological, mental and social functions. One of them is a decline in cognitive function. For the elderly, cognitive decline is a major cause of inability to perform normal daily activities, and is also the most common cause of dependence on others for care dependency. Some risk factors for cognitive decline are age, sex, race, genetics, blood pressure, heart failure, arrhythmia, diabetes, lipid and cholesterol levels, thyroid function, obesity, nutrition, alcohol, smoking, and trauma. This study is a descriptive study that aims to assess the profile of cognitive function and the factors that influence it based on the characteristics of the elderly in the elderly posyandu. Risk factors assessed variables assessed are Age, Sex, Blood Pressure, Body mass index, cognitive function. Cognitive function was assessed with MMSE, blood pressure and body mass index taken was assessed directly. The results of this study found that 85% of the elderly were in the age range of 60-74 years. The most elderly gender in this study sample was Women (70%), 50% of the elderly had hypertension. For cognitive function assessment carried out using MMSE and obtained the results of 90% of the elderly have normal cognitive function, 10% experience mild cognitive function decline. BMI in the elderly in this study obtained mixed figures at most normal BMI 55%, 10% underweight, 2% obesity
Co-Authors Ade Teti Vani Adelin, Prima Ahmad Dzaki Ainun Nabila, Syafa Akbar, Resti Rahmadika Alif Dhuha Anggraini, Debie Anita Darmayanti Aryaldy Zulkarnaini Ashan, Haves Astrid Siska Pratiwi Aulia J Anna Aprilia Meysa Chandra Adilla Denny Rifsal Siregar Dessy Abdullah Dewi, Nadia Purnama Dhuha, Alief Dian Puspita Dian Puspita Dinda Muthia Ferry Iskandar Kahrisma Fidiariani Fikri Alamsyah Fionaliza Fitra Deny Ghaniyyatul Khudri Hansah, Rendri Bayu Helmizar, Roland Heru Herbianto Ika Waraztuty Insil Pendri Hariyani Intan Sesri Winarni Ira Astuti Irma Primawati Irwan Triansyah Irwan Triansyah, Irwan Jefri Henky Jelmila, Sri Nani Kendall Malik Khomeini Khomeini Kurnia Maidarmi Handayani Laura Zeffira liana, nana M. Reyhan Daffa Abdullah Malik, Rifkind Mashdarul Ma’arif Meiriska, Indri Putri Meta Oktora Mhd Nurhuda Mhd Nurhuda Muhammad Ivan Muhammad Ivan Muhammad Rizki Saputra Nadia Purnama Dewi Nana Liana Nani Jelmila, Sri Nasywa Yudeldi Nilas Warlem Nurwiyeni Nurwiyeni Nurwiyeni, Nurwiyeni Pera Siska Raham Triyana Rahma Triana Y Rahma Triyana Revivo Rinda Pratama Riki Nova Rinita Amelia Roland Helmizar Rosmaini Rosmaini, Rosmaini Ruhsyahadati Ruhsyahadati Ruhsyahadati Ruhsyahadati, Ruhsyahadati Safara Innas Salmi Salmi Salmi Sari, Widia Seres Triola Sri Nani Jelmila Tati khairina Thesa Andria Putri Tri Septiana, Vina Tri Yana, Rahma Utari Felia Anggaraini Vani, Ade Teti Vina Tri Septiana Widjaja, Sry Suryani Wisda Widiastuti Yanti Fitri Yasa Yolanda Rahma Donni Yuliza Birman Yuni Handayani YUSTI SIANA Yusti Siana Yusti Siana Yustisiana Yustisiana Zakirullah Zamsari Chan Zukhri Zainun