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Aktivitas Antidiabetes Ekstrak Etanol Daun Jambu Biji (Psidium guajava L.) terhadap Analisis Berat Badan Tikus yang Diinjeksi Streptozotocin Rahayu, Nila Rusdi; Badriyah, Lailatul; Mutripah, Siti
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 2 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i2.448

Abstract

Background: Diabetes mellitus (DM) refers to a medical condition impacting the body's metabolism of lipids, carbohydrates, and proteins, stemming from issues with pancreatic endocrine hormones like insulin and glucagon. This study aimed to test the ability of ethanol extract from guava leaves to reduce blood glucose levels in rats injected with streptozotocin (STZ), and to evaluate the effect of the ethanol extract on food consumption. Methods: This antidiabetic test was conducted on rats injected with streptozotocin (STZ) by measuring the increase in blood glucose levels and body weight in rats experiencing hyperglycemia. The experimental animals were split into four categories, and each category had six rats. The rats in Group I received regular sustenance, the rats in Group II were given CMC Na solution, the rats in Group III received 5mg/kg BW of gliclazide, and the rats in Group IV were administered 300mg of guava leaf extract. A 40mg/kg BW streptozotocin injection was given intraperitoneally on day 0. Blood glucose levels were assessed on days 7, 14, and 21. Data analysis used oneway Anova and followed by The Kolmogorov-Smirnov test was used to assess the normality of the blood glucose and body weight data. Results: The results of study showed On day 21, a significant difference was seen between the STZ-injected group with EEDJ extract treatment 300mg/kg bb and the STZ-injected group intraperitoneally and given Gliclazide 5 mg/kg BW (p<0.05), but there was no significant difference. Conclusion: Administration of EEDJ extract and gliclazide has shown a significant decrease in blood glucose levels and greatly prevent weight loss.
Formulation and Evaluation of Hydrocarbon Ointment from 96% Ethanol Extract of Red Tender Leaves (Syzygium myrtifolium Walp.) Stiyani, Rintika Isa; Mutripah, Siti; Rahayu, Nila Rusdi; Badriyah, Lailatul; Alfiza, Ibnu Syinna
Indonesian Journal of Science and Pharmacy Vol. 3 No. 1 (2025): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i1.105

Abstract

Red Shoot Leaf (Syzigium myrtifolium Walp) has chemical compounds of alkaloids, steroids, triterpenoids, flavonoids, phenolics, and saponins, and has the antibacterial effect of Staphylococcus aureus. This study aims to find out whether Red Shoot leaf extract can be formulated in ointment preparations with hydrocarbon bases and determine the opimal formulation based on physical evaluation. The research was conducted using an experimental method.  Red Shoot leaf extract (Syzigium myrtifolium Walp) was obtained by maceration using 96% ethanol solvent. The extract is formulated into an ointment preparation with three different formulas, namely formula 1 with a variation in the concentration of cera alba 4%, formula 2 with a concentration of cera alba 8% and formula 3 with a concentration of cera alba 12%. The results of the ointment preparations were then evaluated organoleptically, homogeneity, pH, and dispersibility. Based on the results obtained in the spreadability test, it has decreased. The preparation that has the greatest dispersion is found in formula I where the concentration of cera alba used is 4%, while the lowest dispersion is found in formula III with a concentration of cera alba of 12%. Meanwhile, judging from the evaluation of organoleptic, homogeneity, and pH, the three formulas have met the requirements. It can be concluded that 96% ethanol extract of Red Shoot leaves (Syzigium myrtifolium Walp) can be formulated into hydrocarbon ointment preparations and meet the optimal formula requirements, namely 4% and 8% alba cera concentrations.
SCREENING OF SECONDARY METABOLITE COMPOUNDS AND YIELD OF WHITE RHIZOME (Alpinia Galanga L.) EXTRACT THROUGH FOUR EXTRACTION METHODS Badriyah, Lailatul
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 11 No 2 (2024)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/wiyata.v11i2.935

Abstract

Background: Health maintenance can be addressed by the utilization of natural medicines derived from plants called traditional medicine. Traditional medicine can be produced from rhizomes, one of include was the white galangal rhizome. The chemical compounds of white galangal rhizome provide numerous benefits in both culinary and health fields. Objective: to obtain the best yield from the four extraction methods used. The extracts obtained were tested qualitatively using chemical reagents. Method: The method employed was a laboratory experiment utilizing various extraction techniques. The results indicate that the yields from maceration, soxhletation, reflux, and infusion were 11.955%, 20.359%, 15.737%, and 9.416%, respectively. The secondary metabolite compounds found in the white galangal rhizome extract were flavonoids, alkaloids, tannins, terpenoids, and saponins. Conclusions: it can be concluded that the extraction method with the best yield results was the soxhletation method.
Kajian Komparatif Materi Darah Perempuan Pada Buku Teks (PAI BP) dan Buku Fikih Kelas 4 SD Dan MI Badriyah, Lailatul; Atiqullah, Atiqullah; Sa’diyah, Halimatus; Rokib, Moh
JURNAL LENTERA : Kajian Keagamaan, Keilmuan dan Teknologi Vol 24 No 3 (2025): September 2025
Publisher : LP2M STAI Miftahul 'Ula (STAIM) Nganjuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29138/lentera.v24i3.1792

Abstract

Textbooks serve as primary learning resources in schools and are expected to provide accurate, structured, and comprehensive material. This study aims to conduct a comparative analysis of the presentation of female blood material in the Islamic Religious Education and Ethics (PAI BP) textbook for grade 4 students at SD Negeri Tanjung 5 and the grade 4 fiqh textbook at MI Negeri 1 Pamekasan. Specifically, the research seeks to examine (1) the presentation of female blood material in both textbooks, (2) the similarities and differences in their content, and (3) the extent to which the formulation of the material meets students’ learning needs. This research employed a qualitative approach with library research as its design. Data were collected through documentation of primary sources PAI BP textbook (2021) and fiqh textbook (2023), as well as secondary sources from relevant literature. The data were analyzed using content analysis. The findings indicate that the fiqh textbook provides more detailed coverage, particularly on menstruation, including its definition, characteristics, duration, restrictions, and obligatory bathing, while also briefly addressing istihadhah and nifas. In contrast, the PAI BP textbook limits its discussion to menstruation, adopting a narrative and integrative approach that combines fiqh and biological perspectives. Both books share similarities in positioning menstruation within the puberty chapter but differ in depth, argumentation, and evaluation techniques, with fiqh offering broader conceptual-theoretical content than the more contextual narrative of PAI BP.
Pengembangan Kurikulum Berbasis Kebutuhan Peserta Didik: Implementasi Metode UMMI di Sekolah Menengah Pertama akbar, akbar muharom; Badriyah, Lailatul
Journal in Teaching and Education Area Vol. 2 No. 3 (2025): JITERA - Journal in Teaching and Education Area
Publisher : Yayasan Al Hidayah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69673/sfqerm80

Abstract

Penelitian ini bertujuan untuk mendeskripsikan pengembangan kurikulum Pendidikan Agama Islam (PAI) berbasis kebutuhan peserta didik melalui implementasi metode Ummi di Sekolah Menengah Pertama (SMP). Latar belakang penelitian ini berangkat dari fenomena rendahnya kemampuan membaca dan menulis Al-Qur’an peserta didik, khususnya di SMP Pawyatan Daha Kediri. Kondisi tersebut menunjukkan adanya kesenjangan antara capaian pembelajaran PAI dengan kemampuan dasar keagamaan peserta didik.. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus. Data dikumpulkan melalui observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa implementasi metode Ummi mampu menjawab tantangan terkait lemahnya kemampuan membaca dan menulis Al-Qur’an peserta didik. Dengan metode Ummi, peserta didik mengenal huruf hijaiyah dan menghidupkan kembali ingatan membaca Al-Qur’an peserta didik karena sudah berhenti mengaji. Kemudian pengembangan kurikulum menggunakan pendekatan induktif dengan model grassroots, dalam model ini guru PAI berperan sebagai inisiator dan implementator. Guru PAI bersama Kepala sekolah, Waka kurikulum, dan Waka kesiswaan melakukan inovasi pengembangan kurikulum PAI, yaitu dengan memasukkan program baca tulis Al-Qur’an (BTAQ) metode Ummi sebagai bagian integral dari kurikulum dalam pembelajaran PAI. Kebutuhan peserta didik menjadi unsur pertama yang direfleksikan guru PAI dalam menjawab kebutuhan peserta didik. Pendekatan ini berkontribusi terhadap pengembangan kurikulum PAI yang lebih kontekstual dan adaptif.
Co-Authors Muntaha, Amar , LISTYANINGSIH AA Sudharmawan, AA Akbar, Akbar Muharom Alfiza, Ibnu Syinna Ali Haidar Amin, Ahmad Nur Sodiq Aminuyati Anang Firmansyah Anggraini, Nurlia Angraini, Julia Resti Anita Dwi Puspitasari Any Kurniawati, Any Apriani, Ici Aprilia Pangestu Putri, Ayu Ari Darmawan Asih, Eka Nurrahema Ning Atiqullah Aulia, Safana Ayu Pitaloka, Claudia Azhar, Imam Dani Nasirul Haqi Daniel Dike, Daniel Dea, Leli Fertiliana Desiska, Anggelya Dewi Murdiawati Diah Ajeng Palupi Dila, Rahmadani S Dwi Danesty Deccasari Edi Sudiarto Ernawati, Meirina Fauzun Karim, Ahmad Febrianto, Reza Fitriana, Sinta Nur Hanafi Umar Harjito - Haryati, Asti Henni Anggraini, Henni Ilma, Hafizha Intami, Matda Eprina intan permata sari Iqbal, Moch Irsyada, Rahmat Jaria, Ainun Karimatul, Putri Karina, Julia Kesuma, Rismala Khasanah, Atika Huzaifah Kholida Nur Laksono, Gangsar Edi Lubis, Muhammad Al Hasan Luciana Spica Almilia Mahardilla, Devita Mahdi, Imam Makrina Tindangen Mar'atusholikah Mardiana Prasetyani Putri Mardiyanti, Yuniar Marini, Yeni Matda Yunartha Mega Asri, Tri Millati, Silvia Mubarokah, Iin Mufidatul, Ihda Muhammad Arif Rakhman Muhammad Hanif Mukti Amini Mustika, Aisyah mutripah, siiti Mutripah, Siti Navia Syifaurrahmah nenti yulianti Niki Astria Ningrum, Reza Hidayah Nita Cahyani Ni’amah, Siti Nihayatun Noeroel Widajati Noorbaiti, Rahmita Nopi Wulandari Nurselly Oktamah Putri, Kurnia Puspita Sari, wiwied Putri, Ayu Aprilia Pangestu Putri, Marsha Savira Agatha Putri, Naila Nariswari Halisya Rafizah, Nur Rahayu, Nila Rusdi Rahayu, Yashinta W Ramos, Sarah V. Rendy Ariza Pratama Rizky Al Fahmi, Salsabila Rokib, Moh RR. Ella Evrita Hestiandari Salbiyah, Siti Sandra Sukmaning Adji Saputri, Anissa Sarwoko Sarwoko Sa’diyah, Halimatus Senoaji, Fauzie Septia Utami, Tiara Septiana, Devi Septiani, Andina Rizki SITI MUNTOMIMAH, SITI Sonhaji, Ahmad Sri Kadarwati Stiyani, Rintika Isa Sulastri Sulastri Supraptini, Nunuk Sutanta Sutanta, Sutanta Suwandi Suwandi Utami, Tiara Septia vifta, rissa laila Warsono Warsono Wulansari, Destin Retno Yulia, Alma Z. A, Zahroh