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All Journal Media Kesehatan Masyarakat Indonesia Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Jurnal Penelitian Kesehatan Suara Forikes Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Medika Saintika Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo JURNAL KESEHATAN PERINTIS Journal of Midwifery JIK- JURNAL ILMU KESEHATAN Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Andalas Contagion: Scientific Periodical Journal of Public Health and Coastal Health Andalas obstetrics and gynecology journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ners Indonesian Journal of Global Health research JOURNAL LA MEDIHEALTICO Quality : Jurnal Kesehatan Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Berita Kedokteran Masyarakat INPAFI (Inovasi Pembelajaran Fisika) Women Midwives and Midwifery JUKEJ: Jurnal Kesehatan Jompa Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Jurnal Pengabdian Masyarakat Jurnal Sains, Teknologi dan Kesehatan Journal of Clean Technology Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) Jurnal Kesehatan
Yuniar Lestari
Universitas Andalas
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Pengaruh Ekstrak Daun Sirsak terhadap Ekpresi Gen P53 Sel Kanker Payudara T47D Ariesko Gunanda Rangkuti; Dessy Arisanty; Yuniar Lestari
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 2 (2023): Juni 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i2.561

Abstract

Latar Belakang: Kanker payudara merupakan jenis kanker dengan angka kejadiannya menempati posisi pertama terbanyak di Indonesia dibandingkan dengan jenis kanker lain. Daun sirsak yang mengandung acetogenin memiliki efek sitotoksik terhadap sel kanker payudara T47D. Objektif: Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak daun sirsak terhadap level ekspresi gen p53 sel kanker payudara T47D secara in vitro. Metode: Penelitian ini merupakan penelitian eksperimental dengan metode kuantifikasi relatif real time PCR menggunakan cell line T47D diinkubasi selama 72 jam yang dibagi menjadi 2 kelompok sampel, yaitu perlakuan dan kontrol. Kelompok perlakuan diberikan larutan uji ekstrak etanol daun sirsak dengan konsentrasi IC50 = 94,26 µg/ml. Hasil: Hasil nilai Cq dari gen target dan referensi dianalisis dengan menggunakan uji Mann Whitney dan rumus livak. Hasil penelitian didapatkan perbedaan yang bermakna antara kelompok perlakuan dan kontrol dengan nilai p = 0,003 (p < 0,05). Analisis dengan rumus livak menunjukkan adanya peningkatan ekspresi gen p53 sel kanker payudara T47D yang diberi perlakuan, yaitu 2,8015 kali lipat lebih tinggi dari sel kelompok kontrol. Kesimpulan: Ekstrak daun sirsak efektif dapat meningkatkan ekspresi gen p53 pada cell line T47D dan terdapat perbedaan yang bermakna dari nilai Cq gen p53 sel kelompok perlakuan dan kontrol.
PELAKSANAAN KESELAMATAN DAN KESEHATAN KERJA RSUD Dr. MUHAMMAD ZEIN PAINAN TAHUN 2023 Enda Gusnita; Yuniar Lestari; Husna Yetti; Firdawati; Nelmi Silvia; Nizwardi Azkha
Jurnal Endurance Vol. 8 No. 3 (2023): Jurnal Endurance : Kajian Ilmiah Problema Kesehatan
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22216/jen.v8i3.2502

Abstract

ABSTRAK Data laporan kecelakaan kerja RSUD Dr. Muhammad Zein Painan tahun 2019 hingga 2022 tercatat 18 kasus. Penyakit Akibat Kerja yang tercatat corona virus disease 2019, menginfeksi 213 petugas. Tujuan penelitian ini menganalisis pelaksanaan Keselamatan dan Kesehatan Kerja Rumah Sakit. Penelitian dilaksanakan Januari-Juni 2023. Metode penelitian kombinasi (mixed method) model concurrent embedded (campuran tak berimbang). Hasil penelitian kualitatif diketahui bahwa pelaksanaan manajemen risiko belum terlaksana semua ruangan RS, pengukuran lingkungan kerja dan pengukuran sampel personel belum optimal, metode Failure Modes and Effect Analysis belum disusun pada identifikasi risiko keselamatan petugas, untuk pelaksanaan keselamatan dan keamanan RS juga belum terlaksana dengan baik karena masih ditemukan beberapa kasus seperti tertusuk jarum, pasien jatuh, keluarga pasien jatuh, petugas tertimpa. Selain itu, pengawasan beberapa ruangan beresiko masih kurang karena tidak berfungsi kamera pengawas dan tidak memiliki scanner sidik jari. Pelaksanaan pelayanan kesehatan kerja masih belum optimal, hal ini disebabkan karena beberapa aspek kegiatan promotif, preventif, dan rehabilitatif belum terlaksana. Hal ini diperkuat hasil penelitian kuantitatif, ada 3 (tiga) standar dengan persentase yang dinilai tidak baik dari persepsi petugas RS yaitu manajemen risiko (65,9%), keselamatan dan keamanan pasien (63,6%) dan pelayanan kesehatan kerja (70,5%). Pelaksanaan keselamatan dan kerja Rumah Sakit belum terlaksana dengan baik dan belum optimal. Diharapkan Rumah Sakit perlu memenuhi semua standar pelaksanaan dan mengacu peraturan yang berlaku. Kata kunci : keselamatan; kesehatan; kerja; Rumah Sakit Daftar Pustaka : 57 (2018-2023) ABSTRACT Data on work accident reports at Dr. Muhammad Zein Painan Hospital from 2019 to 2022 recorded 18 cases. Occupational Disease recorded corona virus disease 2019, infected 213 hospital staff. The purpose of this study is to analyze the implementation of Hospital Occupational Safety and Health. The research was conducted from January to June 2023. Mixed method research method concurrent embedded model. The results of the qualitative research show that the implementation of risk management has not been carried out in all rooms of the hospital, the measurement of the work environment and the measurement of sample personnel has not been optimal, the Failure Modes and Effect Analysis method has not been prepared for identification of safety risks for officers, for the implementation of hospital safety and security it has also not been implemented properly because still found several cases such as needle sticks, patient falls, the patient's family falls, officers are crushed. In addition, surveillance of some rooms is at risk of still lacking because closed circuit television do not function and do not have fingerprint scanners. The implementation of occupational health services is still not optimal, this is because several aspects of promotive, preventive, and rehabilitative activities have not been carried out. This is reinforced by the results of quantitative research, there are 3 (three) standards with a percentage that is considered not good from the perception of hospital officers, namely risk management (65.9%), patient safety and security (63.6%) and occupational health services (70.5%). The implementation of safety and work of the Hospital has not been carried out properly and has not been optimal. It is expected that the Hospital needs to meet all implementation standards and refer to applicable regulations. Keywords : safety; health; work; hospital Bibliography : 57 (2018-2023)
HUBUNGAN FAKTOR KESEHATAN LINGKUNGAN DENGAN KEJADIAN TUBERKULOSIS DI KOTA PADANG TAHUN 2023 finy marsyah; Yuniar Lestari; Masrul Basyar
Jurnal Endurance Vol. 8 No. 3 (2023): Jurnal Endurance : Kajian Ilmiah Problema Kesehatan
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22216/jen.v8i3.2523

Abstract

Tuberculosis is still a public health problem both in Indonesia and internationally so that it is the goal of the SDGs. In 2021 the number of tuberculosis cases in Padang City was 1,656 cases, the cure rate decreased from 1009 to 457. The death toll increased from 75 to 93. This study aims to analyze environmental health factors associated with tuberculosis. The type of research is quantitative, comparative cross sectional study design. Respondents of the tuberculosis group were tuberculosis sufferers who had lived in the same house with the patient. The non-TB group is not a patient who has been at home with TB sufferers. Data was analyzed using chi square and logistic regression. This research was conducted at 5 Puskesmas in Padang City from June-July 2023. The study showed that 52.8% occupancy density, 45.8% ventilation, 37.5% lighting, 40.3% humidity respondents did not qualify, 98.6% of respondents' house floors were qualified. There are relationships between density (p = 0.034), ventilation (p = 0.005), lighting (p = 0.003), humidity (p = 0.04). The lighting variable is the most dominant variable related to the incidence of tuberculosis in Padang City in 2023. The variable most associated with tuberculosis incidence is lighting. This study found that ventilation is related to tuberculosis, so it needs to be considered in PBG (building approval) to establish rules on the minimum ventilation area requirements as one of the requirements in granting construction approval so that the house becomes healthy and protected from infectious diseases
Utilization of Digital Health Applications in Implementing the Dengue Vector Control Program Sevilla Ukhtil Huvaid; Nursyirwan Effendi; Yuniar Lestari; Hasmiwati Hasmiwati; Afrizal Afrizal; Rizanda Machmud; Nuzulia Irawati; Delmi Sulastri
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 5, No 3 (2023): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v5i3.17232

Abstract

One house one larva monitor movement is a dengue vector control program of the Ministry of Health which has been promoted since 2016. However, there are still several areas that have not been successful in implementing this movement, one of which includes the City of Padang. The purpose of this study was to examine the importance of using digital applications in implementing dengue vector control programs. This research is a research with qualitative methods using the case study genre through a constructivist approach. The location of the qualitative research was carried out at the Padang City Health Office, in the working areas of the Nanggalo Health Center, Pagambiran Health Center, and Rawang Health Center which were designated as research areas. This research was conducted in 2023 with informants including the person in charge of the dengue fever program at the Padang City Health Service, the person in charge of the dengue fever program at the Community Health Center, and the larva monitoring coordinator. The results of the study indicate that efforts to control dengue vectors through the One House One larva monitor Movement are still not running as they should. This movement can only run when larva monitor performs its main tasks and functions in accordance with the provisions. For this reason, it is necessary to carry out coaching and supervision efforts. However, there are several obstacles that require the design of a comprehensive and integrated digital health application to improve the health information system to improve the performance of larva monitors. Keyword:  Dengue Hemorrhagic Fever , Digital Health, Vector Dengue
Hubungan Komorbid dengan Outcome Pasien Terkonfirmasi COVID-19 Di RSUP M. Djamil Padang Tahun 2020 Adiiba Turfha Zahira; Ida Rahmah Burhan; Yusticia Katar; Yuniar Lestari; Fenty Anggrainy; Fathiyyatul Khaira
Majalah Kedokteran Andalas Vol 46, No 10 (2024): Supplementary April 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i10.p1592-1600.2024

Abstract

Tujuan : Penelitian bertujuan Untuk mengetahui hubungan komorbid dengan outcome pasien terkonfirmasi COVID-19 di RSUP. M. Djamil Padang tahun 2020. Metode : Penelitian bersifat analitik observasional dengan pendekatan cross sectional. Data dikumpulkan dan diolah dengan menggunakan teknik total sampling , yaitu semua pasien terkonfirmasi COVID-19 yang dirawat di RSUP M.Djamil Padang berdasarkan kriteria inklusi dan ekslusi . Jumlah sampel penelitian sebanyak 468 pasien terkonfimasi COVID-19 yang dirawat pada periode Maret – Desember 2020. Analisis yang digunakan adalah analisis bivariat berupa Chi-Square . Hasil: Hasil penelitian menunjukkan terdapat hubungan yang signifikan antara komorbid dengan outcome pada pasien terkonfirmasi COVID-19 (p=0,010) di RSUP. M.Djamil Padang. Kesimpulan : Berdasarkan hasil penelitian dapat diartikan bahwa terdapat hubungan antara komorbid dengan outcome pada pasien terkonfirmasi COVID-19.
Tantangan Implementasi Peraturan Daerah tentang Kawasan Tanpa Rokok di Tatanan Perkantoran di Kabupaten Dharmasraya Despariyenita, Despariyenita; Lestari, Yuniar; Ernawati, CH. Tuti
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 2 (2024): April-Juni 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15216

Abstract

Dharmasraya Regency has established a smoke-free area in office settings, but many employees still smoke, so that the community does not implement the policy. The purpose of the study was to determine the implementation of the smoke-free area regional regulation in office settings in Dharmasraya Regency. This study used mixed methods. Data collection was carried out by distributing questionnaires to 130 respondents, interviewing 8 informants and discussions in 2 groups to determine the implementation of the smoke-free area regional regulation according to aspects of communication, resources, disposition and bureaucratic structure. The results of the quantitative analysis showed that most respondents had good knowledge and positive attitudes, but there were still violations. The smoke-free area regional regulation was socialized only once in the early stages, so that communication regarding the delivery of the regulation was cut off and the program did not continue. There had been no commitment or consistency from the leadership, there had been no information media related to the regulation, there had been no application of sanctions for violators, and there had been no evaluation. It was concluded that the smoke-free area policy was not continued, not socialized and not handed over.Keywords: smoke-free area; regional regulation; implementation ABSTRAK Kabupaten Dharmasraya telah menetapkan kawasan tanpa rokok di tatanan perkantoran, tetapi masih banyak pegawai yang merokok, sehingga masyarakat tidak menerapkan kebijakan tersebut. Tujuan penelitian adalah mengetahui implementasi peraturan daerah kawasan tanpa rokok di tatanan perkantoran di Kabupaten Dharmasraya. Penelitian ini menerapkan mix methods. Pengumpulan data dilakukan dengan menyebarkan kuesioner kepada 130 responden, mewawancarai 8 informan dan diskusi dalam 2 kelompok untuk mengetahui implementasi peraturan daerah kawasan tanpa rokok menurut aspek komunikasi, sumber daya, disposisi dan struktur birokrasi. Hasil analisis kuantitatif menunjukkan bahwa sebagian besar responden memiliki pengetahuan baik dan sikap positif, namun masih ada pelanggaran. Peraturan daerah kawasan tanpa rokok disosialisasikan hanya sekali pada tahap awal, sehingga komunikasi penyampaian peraturan terputus dan program tidak berlanjut. Belum ada komitmen atau konsistensi dari pimpinan, belum ada media informasi terkait peraturan, belum ada penerapan sanksi bagi pelaku pelanggaran, dan belum ada evaluasi. Disimpulkan bahwa kebijakan kawasan tanpa rokok tidak dilanjutkan, tidak disosialisasikan dan tidak diserahterimakan. Kata kunci: kawasan tanpa rokok; peraturan daerah; implementasi
Analisis Klinis Hidung Penderita Sindrom Down pada Suku Minangkabau Furqan, Muhammad Afif; Lestari, Yuniar; Irvandy, Dolly; Amir, Arni; Ihsan, Indra
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.609

Abstract

Background: Down's syndrome (DS) is a congenital disorder due to prenatal trisomy 21 which causes malformations of organs and body shape, including the nose. The variables measured are the points that determine the aesthetics of the nose. Purpose: This study aimed to describe primary data thus obtained from nose anthropometry of Down syndrome in the Minangkabau tribe can be used as a reference in nose reconstruction in patients with Down syndrome to restore physiological function and add aesthetic value. Methods: This research is a descriptive type study with a cross-sectional method using primary data as subjects. The sample of this study were people with Down syndrome who have Minangkabau ethnicity, totaling 22 samples with an age range of 13-25 years from special schools in Padang city. The study was conducted by observation and anthropometry of the nose using graphical images computerized by software called rhinobase software. Results: The results of this study showed that the nose width is 15.25 mm ± 2.07, the ala nasi width is 41.41 mm ± 3.47, the nasofrontal angle was 133.59° ± 5.89, the nasolabial angle was 109.24° ± 13.60 , the nose length is 32.16 mm ± 3.24. Conclusion: From this study, various results were found on the size of the aesthetic points of the nose of Down syndrome patients in the Minangkabau ethnic group when compared to DS patients in different race, ethnic, or non DS patients.
Peran Manager dalam Optimalisasi Kinerja Karyawan di Instalasi Farmasi Rawat Jalan Ismed, Gabila Heira Muthia; Semiarty, Rima Yunita; Nurdin, Aguswan; Hardisman, Hardisman; Almasdy, Dedy; Edison, Edison; Lestari, Yuniar
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 3 (2024): Juli-September 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15321

Abstract

A manager is a person who controls a business, involving the process of delegating authority to several people in charge with leadership duties, as well as the process of moving, guiding, and controlling all human and material resources to achieve goals. With the challenge of a high workload, a leader must be able to influence his subordinates in order to provide maximum performance. This study aimed to determine the impact of the manager's leadership role in improving employee performance, at the Semen Padang Hospital Outpatient Pharmacy Installation. The design of this study was cross-sectional. This study used a total sampling technique, so that 30 employees who work in the outpatient pharmacy installation were obtained. Data were collected by filling out a questionnaire, then analyzed using Partial Least Square in order to test the relationship between variables. Based on the results of the analysis, the p value was 0.029 and the T-statistic value was 2.188, which means that the role of the manager has a positive and significant effect on employee performance. Thus, it could be concluded that the role of the manager can optimize the performance of employees at the Semen Padang Hospital Pharmacy Installation.Keywords: manager; leadership; employee performance  ABSTRAK Manager adalah orang yang melakukan pengendalian suatu usaha, melibatkan proses delegasi wewenang kepada beberapa penanggung jawab dengan tugas kepemimpinan, serta proses menggerakkan, memberi bimbingan, dan mengendalikan semua sumber daya manusia dan materi untuk mencapai tujuan. Dengan tantangan beban kerja yang tinggi, seorang pimpinan harus mampu memberikan pengaruh terhadap bawahannya agar dapat memberikan performa kinerja yang maksimal. Penelitian ini bertujuan untuk mengetahui dampak peran kepemimpinan manager dalam meningkatkan kinerja pegawai, di Instalasi Farmasi Rawat Jalan Semen Padang Hospital. Rancangan penelitian ini adalah cross-sectional. Penelitian ini menggunakan teknik total sampling, sehingga didapatkan 30 orang karyawan yang bertugas di instalasi farmasi rawat jalan. Data dikumpulkan melalui pengisian kuesioner, lalu dianalisis menggunakan Partial Least Square dalam rangka menguji hubungan  antar variabel. Berdasarkan hasil analisis, didapatkan nilai p adalah 0,029 dan nilai T-statistik adalah 2,188, yang bermakna bahwa peran manager berpengaruh positif dan signifikan terhadap kinerja pegawai. Dengan demikian bisa disimpulkan bahwa peran manager dapat mengoptimalisasi kinerja pegawai Instalasi Farmasi Semen Padang Hospital.Kata kunci: manager; kepemimpinan; kinerja pegawai
ANALISIS SISTEM PENCEGAHAN DAN PENGENDALIAN KEJADIAN TERTUSUK JARUM SUNTIK PADA PERAWAT DI RSUP DR M DJAMIL PADANG TAHUN 2022 Rumaisha, Rumaisha; Semiarty, Rima; Astiena, Adila Kasni; Lestari, Yuniar; Silvia, Nelmi; Rasyid, Roslaili
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 7 No. 3 (2023): DESEMBER 2023
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v7i3.22319

Abstract

Salah satu dampak negatif yang ditimbulkan oleh proses pelayanan kesehatan yaitu tertusuk jarum suntik (needle stick injury) yang berdampak pada petugas rumah sakit berisiko terpapar darah dan cairan tubuh yang terinfeksi. Berdasarkan laporan komite Pencegahan dan Pengendalian Infeksi Rumah Sakit (PPIRS) RSUP Dr M Djamil Padang di tahun 2019, tahun 2020 dan tahun 2021, terlihat kenaikkan kasus kejadian tertusuk jarum suntik pada perawat, dimana pada tahun 2019 yaitu 22%, di tahun 2020 yaitu 41% dan di tahun 2021 yaitu 48%. Tujuan penelitian ini untuk mengetahui pelaksanaan pencegahan dan pengendalian kejadian tertusuk jarum suntik pada perawat di RSUP Dr M Djamil Padang. Penelitian ini menggunakan metode penelitian yang menggabungkan antara metode penelitian kuantitatif dan kualitatif (mixed methods) dengan desain model concurrent triangulation yaitu dengan cara mencampur kedua metode tersebut secara seimbang. Teknik pengambilan sampel penelitian ini secara proportionate startified random sampling yang berjumlah 90 orang responden. Pemilihan informan penelitian ini dengan purposive sampling yang berjumlah 5 orang informan. Berdasarkan hasil penelitian ini, sebagian besar perawat memiliki pengetahuan yang baik (93,3%) dan sikap positif (84,4%) mengenai pencegahan dan pengendalian kejadian tertusuk jarum suntik. Hasil penelitian menunjukkan bahwa sistem pencegahan dan pengendalian kejadian tertusuk jarum suntik pada perawat di RSUP Dr M Djamil Padang sudah berjalan dengan baik, namun memang ada hal-hal yang perlu menjadi perhatian sebagai penguat sistem sehingga risiko bisa dikendalikan dan berkurang atau tidak adanya kejadian tertusuk jarum suntik bekas pakai. Di sarankan perawat dalam bekerja sesuai standar dan fokus ,meningkatkan pengawasan terhadap penanganan jarum suntik bekas pakai ,meningkatkan monitoring dan evaluasi terhadap pengendalian risiko kejadian tertusuk jarum bekas pakai ,agar rumah sakit melakukan resosialisasi atau pelatihan yang dilakukan secara berkala terhadap penanganan tertusuk jarum suntik bekas pakai kepada perawat.
META-ANALISIS FAKTOR RISIKO INTERNAL DAN KOMORBID YANG BERHUBUNGAN DENGAN KEJADIAN PENYAKIT TUBERKULOSIS DI WILAYAH ASIA Primasari, Eka Putri; Bachtiar, Hafni; Lestari, Yuniar
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 3 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i3.33272

Abstract

Tuberkulosis (TB) merupakan penyakit infeksi menular pembunuh nomor satu di dunia. Secara global, diperkirakan 10,0 juta (kisaran, 8,9-11,0 juta) orang terkena penyakit TB pada tahun 2019. Secara geografis, sebagian besar orang yang mengembangkan TB pada tahun 2019 berada di wilayah WHO Asia Tenggara (44%). Faktor internal seperti usia, jenis kelamin, status gizi, imunisasi BCG dan adanya komorbid seperti infeksi penyakit HIV dan diabetes merupakan faktor risiko penyakit tuberkulosis. Penelitian ini bertujuan mengetahui hubungan faktor risiko internal dan komorbid terhadap kejadian tuberkulosis di Asia. Penelitian ini merupakan penelitian kuantitatif dengan desain studi meta-analisis. Meta-analisis dilakukan terhadap penelitian dengan desain studi kohort dan kasus-kontrol, terpublikasi sejak Januari 1980 sampai Maret 2016, melalui database PubMed, ProQuest, EBSCO dan BioMed Central. Perhitungan pooled odds ratio (OR) dengan asumsi fixed effect model atau random effect model. Data diolah menggunakan RevMan 5.3. Penelitian ini mereview 11.605 artikel, melibatkan 19 artikel ke dalam meta-analisis. Hasil penelitian menunjukkan terdapat hubungan yang signifikan terhadap status gizi <18,5 kg/m2, (OR: 3,71; 95%CI: 1,15 – 12,01), tidak imunisasi BCG (OR: 1,86; 95%CI 1,35 – 2,57), pernah diimunisasi BCG (OR: 0,54; 95%CI: 1,44 – 3,16) dan penyakit diabetes (OR: 1,82; 95% CI 1,51 – 2,18) dengan penyakit TB di wilayah Asia. Kesimpulannya faktor risiko internal dan komorbid yang berhubungan dengan kejadian penyakit TB di wilayah Asia ialah status gizi <18,5 kg/m2, tidak diimunisasi BCG, dan penyakit DM.
Co-Authors Abdi Setya Putra Abdiana Abdiana, Abdiana Ade Asyari Ade Nurhasanah Amir Adiiba Turfha Zahira Adnan, Fitrianti Adrial Adrial, Adrial Afdal Afdal, Afdal Afriwardi Afriwardi Afrizal Afrizal Agustianov, Indah Ahmad Adi Trianto Amel Yanis Anak Agung Gede Sugianthara Anggrainy, Fenty Anita Yulistiani Ariadi Ariadi Ariesko Gunanda Rangkuti Arni Amir Asterina Asterina Astiena, Adila Kasni Aswad, Fitria Asyari, Dian Paramitha Audrey Faiza Rosa Bobby Indra Utama Cimi Ilmiawati, Cimi Dasman, Hardisman Dedy Almasdy Delmi Sulastri Delmi Sulastri Desia, Maya Desmawati Desmawati Despariyenita, Despariyenita Dessy Arisanty Dharma, Fitri Yeni Dita Maharani Dolly Irfandy Donal Ortega Edison Edison Edison Edison Edison, Edison Enda Gusnita Endang Suriani Engga Lift Irwanto Erlinengsih Erlinengsih Ernawati, CH. Tuti Erwani Erwani Eryati Darwin Fadrian, Fadrian Fathiyyatul Khaira Fathiyyatul Khaira, Fathiyyatul Fathma Mardhotilla Fenty Anggrainy Feny Wartisa Fika Tri Anggraini Finny Fitry Yani finy marsyah Firdawati Firdawati Fitri Wahyuni Fitri Yanti Fitria Susanti Fortuna, Fory Friska Eka Fitria Friska Eka Fitria Furqan, Muhammad Afif Hafni Bachtiar Hanum, Fathiya Juwita Hardisman Hasmiwati Hindun Mila Hudzaifah Husna Yetti Huvaid, Sevilla Ukhtil Ice Yolanda Puri Ida Rahmah Burhan Ihsan, Indra Irvandy, Dolly Ismed, Gabila Heira Muthia Jamsari Jamsari Juniwati Juniwati Juniwati Juniwati Juniwati Juniwati Kamal Kasra Kelsy Qoridisa Kumalasari, Intan Laila Isrona Lisma Evareny Liza Andriani Masrul Basyar Menkher Manjas MERISA RISKI Miftah Irramah Mira Eka Putri Muthia Afdhelia Putri Anbiar Narulita, Jaesica Salsabila Dwi Nelmi Silvia Nengcy, Silvia Netti Suharti, Netti Nizwardi Azkha Nur Afrainin Syah Nur Indrawaty Lipoeto Nurdin, Aguswan Nursyirwan Effendi, Nursyirwan Nurul Fitri Nuzulia Irawati Oktalina, Dyanti Oktavenra, Ari Putra, Syandrea Prima Putri, Azhara Dhiya Yosse Putri, Sheila Raden Mohamad Herdian Bhakti Rahmi Hafianti Ramayanti Ramayanti Rauza Sukma Rita Reno Afriza Neri Restu Susanti Rezi Fatrima Surya Rima Semiarty Rizanda Machmud Rosa Juliasari Santioso Rosfita Rasyid Roslaili Rasyid Rudy Afriant Rumaisha, Rumaisha Sabani Sabani, Sabani Salim, Aurelia Agantha Salsabilla, Ainna Fajra Saputri, Winda Dwi Selfi Renita Rusjdi Selvia Emilya Semiarty, Rima Yunita Shabrina, Ranny Surika Martalina Susanti, Yenila Suspenti Dewi Syahnur, Citra Septiyenri Syaiful Indra Taufik Akbar Trianto, Ahmad Adi Ulfa Farrah Lisa, Ulfa Farrah Ulvi Mariati Ulya Uti Fasrini Utami Mayfa Rahmania Vicky Warian Triwibowo Virna Zufti Pratiwi Vivi Triana Wanra, Fadhlan Agusma Widya Handayani Wirsma Arif Harahap Yanasta Moendanoe Yani Anggina Yenila Susanti Yessi Pertiwi Yolanda Syahdia Yulitasari, Yulitasari Yunita Chairani Yusrawati Yusrawati Yusri, Elfira Yusti Siana Yusticia Katar Yusticia Katar, Yusticia Zahira, Adiiba Turfha Zairil Zairil Zudana, Kirana