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All Journal VALENSI Teknologi dan Kejuruan: Jurnal teknologi, Kejuruan dan Pengajarannya JURNAL KIMIA SAINS DAN APLIKASI Jurnal Pendidikan Teknologi dan Kejuruan Al-Manahij: Jurnal Kajian Hukum Islam Media Penelitian dan Pengembangan Kesehatan agriTECH Jurnal Pendidikan Ilmu Sosial R.E.M (Rekyasa Energi Manufaktur) Jurnal Manajemen Pendidikan BERITA BIOLOGI E-Dimas: Jurnal Pengabdian kepada Masyarakat Edukasi: Jurnal Pendidikan Jurnal Pengembangan Teknologi Informasi dan Ilmu Komputer AL-IDARAH: JURNAL KEPENDIDIKAN ISLAM ANNALES BOGORIENSES Jurnal Agrotek UMMat SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Journal of Tropical Crop Science Jurnal Pro Hukum : Jurnal Penelitian Bidang Hukum Universitas Gresik Al - Tadabbur: Jurnal Ilmu Al-Qur'an dan Tafsir GERVASI: Jurnal Pengabdian kepada Masyarakat Teknologi Indonesia JURNAL PANGAN Musamus Journal of Physical Education and Sport (MJPES) Jurnal Teknologi Hasil Pertanian Jurnal Abdimas Madani dan Lestari (JAMALI) APTEK Rayah Al Islam : Jurnal Ilmu Islam Community Development Journal: Jurnal Pengabdian Masyarakat SUHUF: Jurnal Pengkajian Al-Qur'an dan Budaya Journal La Lifesci International Journal of Progressive Mathematics Education JUSTIN (Jurnal Sistem dan Teknologi Informasi) Journal of Office Administration : Education and Practice Jurnal Energi dan Inovasi Teknologi Indonesian Health Issue Tsaqofah: Jurnal Penelitian Guru Indonesia Jurnal Magister Akuntansi Trisakti Jurnal: International Journal of Engineering and Computer Science Applications (IJECSA) Bulletin of Network Engineer and Informatics (BUFNETS) Journal of Educational Management Research PANDU: Jurnal Pendidikan Anak dan Pendidikan Umum JPMAT Prosiding Seminar Nasional Keperawatan Universitas Muhammadiyah Surakarta Al-Qudwah: Jurnal Studi Al-Qur'an dan Hadis El-Mujtama: Jurnal Pengabdian Masyarakat Cocos Bio Journal of Multidisciplinary Inquiry in Science, Technology and Educational Research Jurnal Kefarmasian Indonesia Jurnal Pengabdian Dosen Republik Indonesia (JPDRI) Jurnal Ilmiah Cano Ekonomos Annales Bogorienses Berita Biologi
Ahmad Fathoni
Universitas Darussalam Gontor
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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In-Silico Studies of Potential Anti-Alzheimer Compounds from Spondias dulcis Fathoni, Ahmad; Salma, Aninda; Amilia, Nurul; Rudiana, Tarso
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 2, November 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i2.46175

Abstract

Alzheimer's is a chronic neurodegenerative disease characterized by low levels of acetylcholine and the accumulation of abnormal neuritic plaques, leading to rapid memory decline and cognitive impairment. Compounds found in the kedondong plant (Spondias dulcis) have been reported to exhibit in vitro activity as acetylcholinesterase inhibitors. This study examines the potential of active compounds in Spondias dulcis in their interaction with acetylcholinesterase, an enzyme implicated in the pathogenesis of Alzheimer's disease. The enzyme was obtained from the Protein Data Bank (PDB ID: 4EY7). The test ligands were screened based on Lipinski's rule and docked with the receptor. The results of molecular docking which yielded the five best affinity energy values were followed by ADMET testing (absorption, distribution, metabolism, excretion, and toxicity). The test ligand ellagic acid deoxyhexoside showed binding energy at -11.213 kcal/mol. Molecular dynamics simulations were performed using YASARA with AMBER14 force fields for 50 ns. The test ligand ellagic acid eoxyhexoside showed an MM-PBSA value of -51.277 kcal/mol and exhibited good complex stability with an average total RMSD value of 2 Å and low inter-residue fluctuation values. These findings are consistent with the results obtained from the comparator ligand, donepezil. Therefore, compounds in Spondias dulcis have the potential to act as acetylcholinesterase inhibitors and can be considered for the development of therapies for Alzheimer's disease. 
IMPLIKASI PERBEDAAN RASM USMANI TERHADAP PENAFSIRAN AL-QUR’AN : Studi Analisis Penggunaan Tā’ Marbūṭah dan Tā’ Maftūḥah Pada Kitab Tafsir al-Jāmiʻ li Aḥkām al-Qur’ān Karya Al-Qurṭubī dan Laṭāif al-Isyārāt Karya Al-Qusyairī Fatahillah, Ahmad; Fathoni, Ahmad; Huda, Ade Naelul
Al - Tadabbur: Jurnal Ilmu Al-Qur'an dan Tafsir Vol 10 No 02 (2025): Al-Tadabbur: Jurnal Ilmu Al-Qur'an dan Tafsir
Publisher : Sekolah Tinggi Agama Islam Al Hidayah Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30868/at.v10i02.8974

Abstract

Mayoritas ulama mewajibkan penulisan Al-Qur’an dengan Rasm Usmani Karena ilmu rasm Usmani - sebagaimana ilmu qiraat - saling berkaitan dan tidak bisa lepas dari Al-Qur’an. Terlepas dari tauqīfī atau ijtihādīnya penulisan Al-Qur’an dengan rasm Usmani, nyatanya banyak sekali kata-kata dalam Al-Qu’an yang ditulis berbeda meski berasal dari kata yang sama. Karena setiap kata dalam Al-Qur’an adalah mukjizat, maka munculah beragam produk penafsiran. Dalam memproduksi penafsiran sebagian ulama ada yang memfokuskan pada sisi petunjuk atau pesan dari makna batin atau tersirat (esoterik). Maka dalam penelitian ini penulis mengkaji bagaiman penafsiran Al-Qurṭubī dalam kitabnya al-Jāmiʻ li Aḥkām Al-Qur’ān dan Al-Qusyairī dalam kitabnya Laṭāif al-Isyārāt, yang terkait perbedaan rasm Usmani. Tujuan penelitian ini untuk mengungkap makna esoterik (batin) atau isyarat makna lain yang terdapat pada kedua kitab tersebut dikaitkan dengan perbedaan rasm Usmani. Perbedaan kata dalam rasm Usmani sangatlah banyak, sebab itu penulis hanya memfokuskan penelitian dari penggunaan Tā’ Marbūṭah dan Tā’ Maftūḥah. Penelitian ini menggunakan metode kualitatif, berbasis riset kepustakaan sebagai sumber utama. Adapun rujukan utama penelitian ini adalah kitab Al-Jāmiʻ li Aḥkām Al-Qur’ān dan Laṭāif Al-Isyārāt menggunakan pendekatan deskriptif-analisis, yang kemudian mengkomparasikan kedua kitab tersebut didukung penjelasan dari kitab lainnya. Adapun konklusi (hasil) penelitian ini, penulis berkesimpulan bahwa penafsiran Al-Qurṭubī dalam kitabnya Al-Jāmiʻ li Aḥkām Al-Qur’ān dan Al-Qusyairī dalam kitabnya Laṭāif Al-Isyārāt terdapat makna esoterik (makna batin) yang menyebabkan penulisan huruf akhir Tā’ Ta’nīṡ di beberapa kata yang sama dalam Al-Qur’an ditulis Marbūṭah dan di lain tempat ditulis Maftūḥah, yang sebagian besar adanya kesesuaian penulisan rasm Usmani pendapat al-Dānī dan Abū Dāwud.
METODE PENULISAN SYEKH ‘ABDUL FATTĀH ‘ABDUL GANI AL-QĀḌĪ (W: 1403 H/ 1982 M) DALAM ILMU QIRA’AT : Studi Analisis Kitab al-Wāfī Syarah Asy-Syāṭibiyyah I’tishom Billah, Muhammad Qudwah; Fathoni, Ahmad; Haq, M. Ziyadul
Al - Tadabbur: Jurnal Ilmu Al-Qur'an dan Tafsir Vol 10 No 02 (2025): Al-Tadabbur: Jurnal Ilmu Al-Qur'an dan Tafsir
Publisher : Sekolah Tinggi Agama Islam Al Hidayah Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30868/at.v10i02.9086

Abstract

Ilmu Qira’at adalah salah satu cabang ilmu syar’i yang hampir jarang digeluti oleh para penuntut ilmu sekarang ini. Oleh karenanya para ulama kontemporer berusaha untuk menghidupkannya kembali dengan menulis beberapa karya yang berhubungan dengan Ilmu Qira’at. Salah satu karya yang fenomenal dalam bidang ini adalah kitab “Al-Wāfī fi Syarhi Asy-Syāṭibiyyah” karangan Syekh ‘Abdul Fattāh ‘Abdul Gani Al-Qāḍī (w: 1403 H/ 1982 M), seorang ulama Mesir yang ahli dalam Ilmu Al-Qur’an. Kitab ini berisi penjelasan dari kasidah asy-Syāṭibiyyah yang masyhur karangan imam Asy-Syāṭibī (w: 590 H/ 1142 M) rahimahumallāh. Penelitian ini berbicara tentang metode penulisan yang dipraktikan oleh Syekh ‘Abdul Fattāh dalam kitab Al-Wāfī; dengan tujuan untuk menganalisis latar belakang penulisan kitab, kitab rujukan dalam penulisan kitab, sistematik dan metode penulisan kitab. Penelitian sejenis ini telah dikaji oleh beberapa peneliti sebelumnya, akan tetapi semua penelitian tersebut tidak mengkaji metode penulisan kitab Al-Wāfī secara khusus, hanya menjelaskan secara umum kiprah Syekh ‘Abdul Fattāh dalam bidang Al-Qur’an melalui karya-karyanya. Oleh karena itu studi komprehensif kitab Al-Wāfī belum ada yang mengkajinya sampai saat ini. Penelitian ini bersifat kualitatif dengan jenis penelitian library research atau kajian pustaka melalui pendekatan historis, kritis dan filosofis. Sumber data primer dalam penelitian adalah kitab Al-Wāfī yang diterbitkan oleh Dār As-Salām Kairo (2013), cet. ke-9 dan ¬kitab Asy-Syāṭibiyyah tahkik Syekh Tamīm Az-Zu`bi, dengan didukung oleh kitab-kitab qira’at, bahasa dan hadist sebagai sumber data sekunder. Hasil dari penelitian ini adalah: Syekh ‘Abdul Fattāh membagi syarah kitab Al-Wāfī kepada dua bagian utama, yaitu makna bahasa dan makna umum. Syekh ‘Abdul Fattāh banyak memberikan contoh dari Al-Qur’an saat mensyarah kitab. Terlihat dalam kitab ijtihad Syekh ‘Abdul Fattāh dalam menjelaskan makna bait dan tarjih syarah bait dan hukum suatu bacaan.
Phytochemical Profiling of Methanolic and Ethanolic Extracts of Pemphis acidula (J.R.Forst. & G.Forst.) Leaf using LC–MS/MS and GC–MS Sakinah, Putri; Fathoni, Ahmad; Sinaga, Ernawati
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 2, JULY-DECEMBER 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pemphis acidula (J.R.Forst. & G.Forst.) is a mangrove species of the Lythraceae family widely distributed along the Indonesian coasts. Traditionally used for medicinal and cosmetic purposes, information on its phytochemical composition remains limited. Comprehensive chemical profiling is essential to elucidate its bioactive potential and development. This study aimed to identify, characterize, and compare the phytochemical and bioactive profiles of methanolic and ethanolic extracts of Pemphis acidula using LC–MS/MS and GC–MS to determine which solvent yields richer bioactive composition. Leaf samples were collected and authenticated at Herbarium Bogoriense (BRIN). The dried powders were extracted with methanol or ethanol by triple maceration for 24 hours, and filtrates were evaporated under reduced pressure. Crude extracts were analyzed using LC–MS/MS (UPLC-QTOF, ESI ±) and GC–MS; compound identification employed UNIFI software referencing the Waters Traditional Medicine Library and Wiley 275 database. The results showed that LC–MS/MS identified 25 compounds in methanolic and 49 in ethanolic extracts, while GC–MS detected 13 and 19 compounds, respectively, with quality matches ≥90%. These compounds comprised alkaloids, flavonoids, phenols, polyphenols, and terpenoids with antioxidant, anti-inflammatory, antibacterial, antiviral, and anticancer activities. Eleven non-volatile compounds were identified in both extracts, namely kaempferol-3-glucuronide, desmanthin, quercetin-3-O-α-D-glucuronide, quercetin-3-O-glucuronide 6″-methylester, ellagic acid, Z-ligustilide, melazolide A, cimicifugic acid B, vellerdiol, 5,6,7,7α-tetrahydro-4,4,7α-trimethyl-2(4H)-benzofuranone, and farnesyl acetate and seven volatile compounds were identified in both extracts, i.e. supraene, hexadecanoic acid methyl ester, loliolide, 9,12-octadecadienoic acid (Z,Z)-methyl ester, phytol, 9-octadecenoic acid, and tocopherol. In conclusion, Pemphis acidula extracts contain bioactive compounds with medicinal potential, and ethanol extract yielded a broader phytochemical profile than methanol’s.
ANALYSIS OF THE MEANING SHIFT OF THE LOANWORD TECHNOLOGY IN INDONESIAN USING THE WORD EMBEDDING TECHNIQUE Fathoni, Ahmad; Mawe, Hannatul; Alfan Habib, Muhammad; Fitriani, Fitriani
Bulletin of Network Engineer and Informatics Vol. 3 No. 2 (2025): BUFNETS (Bulletin of Network Engineer and Informatics) October 2025
Publisher : PT. GWEX NET PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59688/793c4528

Abstract

The development of information technology has encouraged the widespread adoption of technology-related loanwords in the Indonesian language, particularly in digital communication. The intensive use of these loanwords across diverse contexts has led to semantic shifts in their meanings. This study aims to analyze semantic shifts in technology-related loanwords in Indonesian by employing word embedding techniques as a computational linguistic approach. The research adopts a quantitative method based on the analysis of Indonesian digital text corpora representing language use across different time periods. The data are analyzed through text preprocessing, word embedding modeling, and the measurement of semantic relationship changes using cosine similarity and nearest-neighbor analysis. The results indicate that several technology-related loanwords have undergone significant semantic shifts, including meaning expansion, changes in semantic associations, and shifts in usage functions in line with technological developments and digital culture. These findings demonstrate that word embedding techniques are effective for empirically detecting semantic shifts in Indonesian. This study is expected to contribute methodologically to Indonesian semantic studies and to enrich corpus-based computational linguistics research.
The Effect of Variation of Types of Microbial Starters on The Physical Characteristics of Modified Cassava Flour (MOCAF) Rich in Beta-Carotene Alfansuri, Habib Ra'uf; Fatoni, Rois; Fathoni, Ahmad; Setiarto, R. Haryo Bimo; Damayanti, Ema
Jurnal Teknologi Hasil Pertanian Vol 16, No 2 (2023): Agustus
Publisher : Universitas Sebelas Maret (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jthp.v16i2.73249

Abstract

The development of beta-carotene-rich mocaf flour as a functional food aims to increase its nutritional content and functional properties as an antioxidant for health. The development of beta-carotene-rich mocaf flour can be optimized through good fermentation methods, especially with the use of starter. This study aims to further analyze the effect of using a type of starter on the mocaf characteristics of cassava species rich in beta-carotene through a comparison of several types of starter. In this study, three types of starter were used, namely the Bimo-CF starter, the Berhasil starter and thse BRIN starter. The results showed that the use of starter during fermentation affected the physicochemical properties of mocaf flour in the form of differences in solubility, increased viscosity and decreased syneresis. Scanning Electron Microscope (SEM) was used to analyze the microstrutural of mocaf flour using starter during fermentation resulted in a more massive reshuffling of starch granules and causes changes in the structure of starch granules that become irregular round in shape with increasingly non-uniform sizes. NIR (Near infrared) and proximate analysis of the content of mocaf flour, showed that the use of the Bimo-CF starter, the Berhasil starter and the BRIN starter during fermentation affected the decrease in moisture content, protein content, ash content, fiber content, phosphorus, and increased fat and dry matter content.
Pemanfaatan Liveworksheets dalam Pengembangan Media Pembelajaran Interaktif bagi Guru Madrasah Ibtidaiyah Gisikdrono: Indonesia Subowo, Moh Hadi; Fathoni, Ahmad; Putra, Makhrus Nanda
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 08, Issue 2, September 2026
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol8.iss2.art3

Abstract

Digital transformation in education requires Madrasah Ibtidaiyah (MI) teachers to develop interactive learning media that align with the characteristics of digital-age learners. However, learning practices at MI Gisikdrono Semarang remain dominated by conventional methods, despite the availability of ICT facilities and internet access. This community service program aims to enhance teachers’ understanding and skills in using Liveworksheet as an interactive learning medium, identify challenges in digital media development, and evaluate its effectiveness in supporting students’ learning motivation based on teachers’ perceptions and limited classroom implementation. The program employed a Participatory Action Research (PAR) approach through participatory problem identification, joint planning and action, and collective reflection. Participants were 10 MI teachers who took part in Focus Group Discussions (FGD) and learning-by-doing training on developing interactive student worksheets (LKPD) using Liveworksheet, followed by independent assignments and product assessment using a rubric. The results show strengthened digital competence and creativity among teachers, reflected in their ability to design interactive LKPD and increased confidence in using digital media. All participants produced at least one Liveworksheet-based learning medium suitable for classroom use based on curriculum relevance, clarity of instructions, visual design, and interactivity. Teachers perceived Liveworksheet as easy to use and capable of increasing student engagement. The program indicates that Liveworksheet effectively supports digital learning transformation in Madrasah Ibtidaiyah.
Co-Authors -, Munoto Abdul Aziz Abdul Basid Abdul Hakim Abdul Muhaimin, Abdul Adi Supratikto, Adi Ahmad Muhibbin Ahmad Zain Sarnoto Aini, Isnawatul Akbar, Muhammad Aminul Aldy, Aldy Alfan Habib, Muhammad Alfansuri, Habib Ra'uf Alfi Rahmi, Alfi Amilia, Nurul AMINUDIN ANDRIA AGUSTA Anjis Sapto Nugroho Anshori, Muhammad Helmi Anton Anton Antonius Herry Cahyana Aprilia, Aqsha Putri Arginia, Della Arif Nurkanto Arif Rahman Saleh Arip, Moh Astuti, Tri Dwi Ayuniyyah, Q Azhar, Fachri Azis, Sri Misykat Azmi Asra, Azmi Azmi, Aulul Baiq Desi Dwi Arianti Dewi Sukma DEWI WULANSARI Dian Kristiawan Nugroho Dody Pratama Marumpe Durinda Puspasari Efendy, Oscar Effendi, Oscar Eko Supriyanto Ema Damayanti Emilyani, Desty Erik Estrada Ernawati Sinaga Erni Romansyah Euis Ismayati Farooq, Omar Fatahillah, Ahmad Fathoni, Rois Fitriani Fitriani Fitriyanto, Arief Hafid, Lukman Haq, M. Ziyadul Hard, Rasyd Hariadi Hariadi Hariyanto Hengky Anra Heri Kuswanto Hidayatullah, Tobib Huda, Ade Naelul Huda, Ahmad Akromul Ida Wahyuni Ikhsan Gunawan Indra Himayatul Asri Irdawati, I Irma Sari Ismatullah, Kholida Ismiyarto Ismitarto I’tishom Billah, Muhammad Qudwah Jamaludin . Jeong, Soo Kyoung Jeong, Soo Kyoung Kamal, Andi Saptaji Kamaludin, Basori Kartika Dyah Palupi Karyanik, Karyanik Keim, Ary P Khairunnisa, Imma Jannati Khoirul Muhtadin Kholisho, Yosi Nur Kim, Joon Kyun Kim, Joong Kyun Legisnal Hakim lina marlina, lina Lufita Nur Alfiah Maksum, M. Syukron Maliq, Nina Marianah, Marianah Markhamah Mawe, Hannatul Mayasti, Nur Kartika Indah Mohammad Fathi Royyani, Mohammad Fathi Mohammad Irfan Molo, Hasanuddin Muhamad Arpan Muhammad Ilyas Muhammad Ramli Muliatiningsih Muliatiningsih Mustafidah, Mabrurotul Mu’iz Widayat, Walid N. Sri Hartati, N. Sri Naelul Huda, Ade Ngadiwiyana M.Si. S.Si. Nofriser, Nofriser Nunung Ariandani Nur Annisa Istiqamah Nur Halifa Nurhayati, Nurhayati Nurhikmah Sasna Junaidi Sasna Junaidi, Nurhikmah Sasna Junaidi Sasna Nurlaela, Lutfiyah Oktiva, Yayuk Dwi Pipit Irawati Prabowo, Ardian Adi Pramono Pramono Praptiwi Praptiwi Prastiwi, Erfa Kurnia Purwo Subekti Puspa, Rahma Putra, Aldho Pramana Putra, Makhrus Nanda Putra, Reinaldo Dede Putri, Ade Lia Putu Sudira R. Haryo Bimo Setiarto, R. Haryo Bimo Raden Haryo Bimo Setiarto, Raden Haryo Bimo Rahmawati, Rika Sri Rois Fatoni Royani, M Fathi ryanjani lila anggraita SAKINAH, PUTRI Salma, Aninda Sandra Hermanto Saputra, Andra Sasna Junaidi, Nurhikmah Septiana, Nurwinda Sari Sintho Wahyuning Ardie Subowo, Moh Hadi Sudarsono Sudiyanto, I wayan Suhairin, Suhairin Supari Muslim Suryansah Syafri Edi Syamsiar, Syamsiar Syirril Ihromi, Syirril Tanjung, H Tarso Rudiana, Tarso Tiwi, Praptiwi Tri Afirianto, Tri Tri Murningsih, Tri Tri Rijanto Tursina Tursina Uska, Muhammad Zamroni Visto, Yohanes Wahyudi Wahyudi Wariso Wariso, Wariso Wazni, M Khairul Wijoyo, Moh. Noer Tondo Winna Dharmayanti Yeza Febriani Yose Rizal Yuliasri Jamal Zaki Al Fatih, Moh Zakiy, Ahmad Zuliawan, Ikbal