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All Journal Biospecies Edu-Sains: Jurnal Pendidikan Matematika dan Ilmu Pengetahuan Alam Sainmatika: Jurnal Sains dan Matematika Bioma : Berkala Ilmiah Biologi Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati SEMIRATA 2015 JPS Unimus Abjadia, International Journal of Education JURNAL PENDIDIKAN TEMATIK DIKDAS IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Jurnal Penelitian Sains Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Penelitian Pendidikan IPA (JPPIPA) BIOEDUKASI Jurnal Biologi Tropis EKSAKTA : Jurnal Penelitian dan Pembelajaran MIPA PENDIPA Journal of Science Education Diklabio: Jurnal Pendidikan dan Pembelajaran Biologi Biosaintifika: Journal of Biology & Biology Education Journal of Education and Instruction (JOEAI) BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Bio-Lectura Jurnal Iktiologi Indonesia (Indonesian Journal of Ichthyology) Jurnal Pendidikan Fisika dan Teknologi EDUKATIF : JURNAL ILMU PENDIDIKAN Jurnal Gentala Pendidikan Dasar Jurnal Mantik JURNAL PENDIDIKAN MIPA Biopendix: Jurnal Biologi, Pendidikan dan Terapan Dedikasi: Jurnal Pengabdian Masyarakat Jurnal Biogenerasi Jurnal Ilmiah Profesi Pendidikan Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Paedagogy BioEksakta : Jurnal Ilmiah Biologi Unsoed Indigenous Biologi Didaktika: Jurnal Kependidikan Integrated Science Education Journal GANESHA: Jurnal Pengabdian Masyarakat Al Jahiz: Journal of Biology Education Research JURNAL MUARA PENDIDIKAN Jurnal Pemberdayaan Masyarakat Nusantara Physics and Science Education Journal (PSEJ) Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Proceeding Seminar Nasional IPA JUPEMA Jurnal Intelek Insan Cendikia Biodik: Jurnal Ilmiah Pendidikan Biologi Polygon: Jurnal Ilmu Komputer dan Ilmu Pengetahuan Alam Jcommits : The Journal of Community Empowerment, Innovation, and Sustainability Jurnal Cakrawala Pendidikan dan Biologi (jucapenbi)
Afreni Hamidah
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The Effect of Problem Based Learning (PBL) Model Based on Local Wisdom to Improve Students' Critical Thinking Skills Sri Anika Cahayu; Jodion Siburian; Afreni Hamidah
Integrated Science Education Journal Vol 5 No 2 (2024): May
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/isej.v5i2.985

Abstract

Purpose of the study: The purpose of this study was to determine the effect of problem-based learning (PBL) model based on local wisdom in making lemang kancung beruk to improve students' critical thinking skills. Methodology: The research method is a quasi-experimental form of non-equivalent pretest-posttest control group design with non-probability sampling technique-purposive sampling. The data collection techniques used critical thinking skills tests with FRISCO indicator essay tests and observation sheets. Technical data analysis used Analysis of covariance (Ancova) test and quantitative descriptive approach used SPSS 20 program. Main Findings: The research results of the Ancova hypothesis test show that the corrected model sig value is 0.000 <0.05, then H0 is rejected and H1 is accepted, This means that the problem-based learning (PBL) model based on local wisdom in making lemang kancung beruk has a significant and moderate effect on improving students' critical thinking skills. Novelty/Originality of this study: The novelty of this research is the implementation of problem-based learning (PBL) model based on local wisdom of Kerinci-Sungai Penuh area in science learning. The limitations in the study are the competencies measured in the integrated essay test and the subject matter is the science material of substances and their changes in class VII.
Mouse Models in Sarcopenia Research: A Literature Review Julia, Putri; Nani Asyahri; Fitriya Setiani; Lili Sardona; Jodion Siburian; Afreni Hamidah; Desfaur Natalia
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12446

Abstract

Sarcopenia is defined as the progressive decline in skeletal muscle mass, strength, and function associated with the aging process. This literature review aims to analyze various mouse models used in sarcopenia research, with a primary focus on the C57BL/6 strain. A narrative literature review was conducted systematically by searching the Scopus and Google Scholar databases using the keywords “sarcopenia”, “mouse model”, “muscle atrophy”, and “C57BL/6”. A total of 12 relevant articles published between 2020 and 2024 were selected based on the inclusion criteria.The analysis results showed that muscle mass decline in mice generally begins progressively at the age of 18–24 months and becomes more significant at 23-32 months, with male mice being more susceptible than females. Natural aging, dexamethasone induction, and immobilization models were the most frequently used, consistently demonstrating type II fiber atrophy, mitochondrial dysfunction, increased ROS, and suppression of the mTORC1 pathway. Therapeutic candidates such as Delta-Like 1 Homolog (DLK1) and Ulmus macrocarpa extract showed promising effects in reducing muscle atrophy. Although mouse models provide valuable insights into the mechanisms of sarcopenia, biomechanical differences and sex-specific responses between mice and humans must be considered to enhance the translational value of the research. This review is expected to serve as a reference for researchers in selecting the appropriate mouse model for sarcopenia studies.
Co-Authors A. Yani Adha Febrianti ADRIANI ADRIANI Ady Mara, Ady Agus Subagyo Agustina, Nurria Ali Sadikin Ali Sadikin Alia Petra Siboro Amalia, Richa Amatullah, Tara Fadhila Andreo Satria Angga Bagas Saputra Anggreini , Evita Apdoludin Apdoludin, Apdoludin Aprizal Lukman Ardi Mustakim Asrial Aswan, Dara Mutiara Bambang Hariyadi Bambang Haryadi Bela Mustika Bestia Dewi Bestia Dewi Bunga Deli Anjani Cahayu, Sri Anika Cinta Serlina Danial Mursyd Daniel Alfarado Dara Mutiara Aswan Dari, Riski Kurnia Daryanto Daryanto Dawam Suprayogi Delisa Rizkiani Della Wirsal Desfaur Natalia Desfaur Natalia Desfaur Natalia Desnelli Desnelli Dewi Febrianty Diah Sefti Ayunasari Dian Arisandy Eka Putra Sembiring DINI MAIDIKA Dodi Devitriano Dwi Lestari Aryani Dwi Maihidin Pahlifi Elisa Nurnawati Ema Faorika Era Mustika Sari Eri Mangaranap Erick Sanjaya Ervan Johan Wicaksana Ester Br Aritonang Eva Musifa Evita Anggereini Evita Anggereini Evita Anggereini Fadhilah, Rifda Zaiza Fatma Fatma Fela Rahmadiyanti Ferlinahayati Ferlinahayati Fira Nur Fatimah Fitri Amelia Fitriya Setiani G. Gunawan Gardjito Gardjito Gusliani Gusliani Gusliani, Gusliani Hadyanto Hadyanto Hakim, M. Arif Rahman Hakim, Nasrul Hamzah Hamzah, Hamzah Hariyadi , Bambang HARLIS Harlis Hawalya, Hawalya Heni Yohandini Hutwan Syarifuddin Hutwan Syarifuddin Iklimalia, Iklimalia Ilham Falani Indana Zulfa Ine Tentia Jalius Jalius Jalius Jastiana, Diel Aknova Jeni Khusnelia Jodion Siburian Jodion Siburian Julian Pratama Juniandra, Rezha Kayla, Nabila Khaerudin Khaerudin Khairul Mustopa Lili Sardona Luthfi Dhia Putri M. Erick Sanjaya M. Farhan Aditiya Mardhotillah, Bunga Maretha Ayu Angel Lestari Mariza Fiska Mega Fatimah Rosana Meitafia, Elda Meitafia Melly Dwi Febriani Mia Aina Mia Aina Miftahul Jannah Muhaimin Muhaimin Muhamad Tommy Muhammad Erick Sanjaya Muhammad Haris Effendi Hasibuan Muhammad Said Muhammad Yusuf Mursyd, Danial Mustika Sari, Wiwit Muswita Muswita Muswita Mutmaenah, Shucy Nailla Ramadani Nani Asyahri Napitupulu, Debora Chalista Nasrul Hakim Natalia , Desfaur Nazurty Nazurty Nirmala Nirmala, Nirmala Novita Sari Novti Lastri Nur Rohman Nurjanah Nurjanah Nurjannah Pratiwi NURRUDIN NURRUDIN Pandiangan, Tantri Ayu patmi, patmi Pinta Murni Putri Julia, Putri Putri, Oktaria Dwi Qalbi Shanaz Anandari Rachmat Meydi Rahayu, Erni Raissa Mataniari Rani Puji Saputri Rauda Syafitri Retni Budianingsih Retni S Budiarti Retni Sulistiyoning Budiarti Revis Asra Rialdy, Alfajar Richa Amalia Ridoi Warneck Siburian Risnita Risnita Risnita Risnita Rz, Rusnelly Isrika Salsabila, Niken Alya Salsabila, Syifa Sanjaya, M. Erick Saparuddin Saparuddin Septia, Adela Eka Siska Safitri Siti Aisyah Siti Aisyah Aisyah Siti Khoiriah Siti Khoiriah Soedjatmiko Sonya Asokawati Sri Anika Cahayu Sri Anika Cahayu Sri Susanti Suci Okta Piyana Suheyanto Suheryanto Suzanti, Sriliah Syahrial, Syahrial Syaturoifah, Anis Tantri Margayu TATI NURHAYATI Taufik Pramudya Tedjo Sukmono Tia Wulandari Tiara Aprilini Tiara Balqis Upik Yelianti Urip Sulistyo Vera Yulanda Wella Yosvita Sari Wendra Priatama Wilda Syahri Winda Dwi Kartika, Winda Dwi Yafitriani Loi Yunita Veronika Yunita Veronika Yusra, Affan Zahra, Mahar Hazzillia Az Zekmana, Benni Zurweni Zurweni