Introduction: Cardiometabolic diseases, particularly hypertension and diabetes, are rising in prevalence among adults in semi-urban regions of low- and middle-income countries. Early detection at the community level is essential to reduce complications and promote preventive action. This study aimed to identify early indicators of cardiometabolic risk through a nurse-led community health screening in Bukittinggi, West Sumatra, Indonesia. Methods: A descriptive cross-sectional design was conducted as a one-day service-learning outreach involving nursing faculty, undergraduate students, local health cadres, and community leaders. Adults aged 18 years and above were recruited using consecutive sampling. Preparations included coordination with local stakeholders to ensure community participation. Screening activities comprised blood pressure measurement, random blood glucose testing, body mass index (BMI) calculation, and structured interviews on behavioral risk factors. A total of 80 participants completed the screening, and data were analyzed descriptively. Results: 80 participants, 64 (80%) had elevated blood pressure ranging from prehypertension to hypertensive crisis, 21 (26.3%) showed abnormal blood glucose levels consistent with prediabetes or diabetes, and 42 (52.5%) were overweight or obese. Additionally, 77 participants (96.3%) reported low physical activity and inadequate fruit and vegetable intake, indicating a high clustering of modifiable cardiometabolic risk factors. Conclusion: This study highlights the burden of modifiable cardiometabolic risks in semi-urban communities and demonstrates the feasibility of nurse- and community-led health screenings for early detection. For sustainability and broader impact, future programs should be strengthened through collaboration with health cadres, primary health centers, and community leaders, combined with follow-up education and integration into primary healthcare services.