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All Journal SUPREMASI: Jurnal Pemikiran, Penelitian Ilmu-Ilmu Sosial, Hukum dan Pengajarannya Al-Risalah : Jurnal Imu Syariah dan Hukum Journal of Agromedicine and Medical Sciences Acta Pharmaceutica Indonesia Jurnal Pengabdian UntukMu NegeRI Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA Jurnal Biotek Jurnal Dunia Farmasi Jurnal Ilmiah Manusia dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Abdi Insani Jurnal Kesehatan Tambusai Jurnal EduHealth Acta Islamica Counsenesia: Counselling Research and Applications Jurnal Farmasi Sains dan Praktis FARMASAINKES Journal of Pharmaceutical and Sciences. Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara
Muhammad Amin Nasution
Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Al Washliyah, Medan, 20147, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Penetapan kadar flavonoid total ekstrak etanol, fraksi etil asetat dan n-heksan pada daun kakao (Theobroma cacao L.) dengan metode spektrofotometri uv-vis Zikra Maqfirah; Muhammad Amin Nasution; M. Pandapotan Nasution; Haris Munandar Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.43

Abstract

Cocoa (Theobroma cacao L.)  is a plant that is cultivated on plantations in Indonesia. One part of the cacao plant that has the potential to be developed as a traditional medicine is the cacao leaf because it contains secondary metabolites of flavonoids. Flavonoids have many properties, including acting as antioxidants, protecting cell structures, anti-inflammatories, preventing osteophoresis, and antibiotics. The purpose of this study is to determine the content of secondary metabolites and total flavonoid levels in ethanol extract, ethyl acetate fraction and n-hexane in cocoa leaves. In this study, the initial steps taken are sample collection, sample processing into simplicia, simplicia characterization test then preparation of cocoa leaf ethanol extract by maceration method using 70% ethanol solvent, followed by partitioning process with liquid-liquid extraction method to obtain ethyl acetate fraction and n-hexane and phytochemical screening is carried out. Determination of total flavonoid levels using the UV-vis spectrophotometric method at a wavelength of 437 nm with quercetin as a comparison.The results of this study showed that a cocoa leaf ethanol extract contains alkaloid compounds, flavonoids, tannins, saponins, steroids and glycosides, the ethyl acetate fraction contains alkaloid compounds, flavonoids, tannins, steroids and glycosides, while the n-hexan fraction contains alkaloid compounds, flavonoids and steroids. Total flavonoid levels in cocoa leaves from an ethanol extract amounted to 39.1422±0.0540 mg QE/g, ethyl acetate fraction 45.274±0.0629 mg QE/g and n-hexane fraction 21.4812±0.7048 mg QE/g. The highest flavonoid levels are obtained in the ethyl acetate fraction.
Penetapan Kadar Kafein Ekstrak Daun Teh Hijau Dan Putih Camellia Sinensis (L.) Dengan Kromatografi Cair Kinerja Tinggi Selfia Lestary; Muhammad Amin Nasution; Ridwanto Ridwanto; Haris Munandar Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.199

Abstract

Tea, a widely popular and frequently consumed beverage, is integral to daily routines. Despite the potential long-term risks associated with excessive caffeine consumption, such as hypertension, heart disease, and stroke, caffeine is a prominent choice among a diverse spectrum of individuals in society. The objective of this research endeavour is to discern the caffeine content present in extracts derived from green and white tea leaves by applying the high-performance liquid chromatography (HPLC) method. The research procedure encompasses a series of stages, encompassing the preparation of botanical materials, extraction employing ethanol solvent, characteristic analysis, phytochemical screening, and quantification of caffeine levels within the green and white tea leaf extracts utilising the HPLC technique. The extraction process of green and white tea leaves entails maceration utilising 96% ethanol, followed by concentration via a rotary evaporator. The determination of caffeine concentrations is executed using the high-performance liquid chromatography method. A phytochemical screening analysis of ethanol extracts derived from green and white tea leaves unveiled a myriad of chemical compound classes, including alkaloids, flavonoids, saponins, tannins, and steroids. The quantification of caffeine content within the samples is ascertained by calculating the area under the curve (AUC) on the chromatograms of green and white tea extracts. The quantification results for caffeine content in the green tea extract reveal a value approximately equivalent to 98.4278069571 mg/g. The white tea extract demonstrates a content value of approximately 136.131488681 mg/g.
Fermentasi kombucha bunga telang (Clitoria ternatea L) sebagai produk bioteknologi sederhana dalam memberikan reaksi farmakodinamik mencit (Mus musculus L) yang terpapar asap rokok dan morfometri ovarium Dwiyarina Margarisa; Firman Rezaldi; Isti Dwi Pruschia; Muhammad Andry; M. Fariz Fadillah; Mutia Muhardiyanti; Hendra Jaya; Leni Halimatusyadiah; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.254

Abstract

One of the fertility indicators in women is the optimal functioning of the ovaries. Exposure to cigarette smoke affects the decline in ovarian function in quality and quantity. The main components contained in cigarette smoke include tar, nicotine, carbon monoxide, inorganic gases, heavy metals, nitrosamines, carbonyls, formaldehyde, and polynuclear aromatic hydrocarbons. The main components contained in cigarette smoke positively influence female reproductive hormone levels and even reduce fertility. One of the efforts to prevent free radicals from cigarette smoke and have the potential as a natural antioxidant is consuming butterfly pea flower kombucha. The butterfly pea flower kombucha from previous studies contains phytochemicals that can inhibit free radicals. This study aimed to study the effect of butterfly pea flower kombucha on the ovary morphometry of female mice exposed to cigarette smoke. The design of this study was Completely Randomized Design (CRD). The test animals used were female mice aged 10 to 12 weeks weighing 20 to 20 g in a total of 24 mice. The butterfly pea flower kombucha given was ten mL/L, 20 mL/L, 30 mL/L, and 40 mL/L. Cigarette smoke exposure to mice was carried out on days 1-20 as much as one stick and treated with butterfly pea flower kombucha on days 21-40. Mating of female mice was carried out on the 40th day. Observations of ovarian morphometry such as length, width, weight, and number of corpus luteum were carried out on the 18th day of gestation. ANOVA and DMRT with a confidence level of 1% is the data analysis performed. The conclusion of this study was that butterfly pea flower kombucha had a good effect on improving fertility levels, which could be observed with test parameters such as length, width, weight, and number of corpus luteum and administration of kombucha with a concentration of 40 mL/L was the best treatment.
Penetapan Kadar Kafein Dari Ekstrak Daun Kopi Robusta (Coffea canephora Pierre ex A. Froehner) Dan Daun Kopi Arabika (Coffea arabica L.) Dengan Metode Kromatografi Cair Kinerja Tinggi. Tri Damaiyanti; Muhammad Amin Nasution; Haris Munandar Nasution; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.257

Abstract

Coffee is a plant that contains caffeine and can be processed into a delicious drink. Currently, it has achieved very high popularity throughout the world, ranking second after water and tea in the list of most preferred drinks. Coffee drinks are popular with various groups, from teenagers to adults, and in Indonesia, coffee is even the most giant drink consumed, only behind water in consumption levels. On average, people consume coffee around 3-4 times a day, reflecting how popular this drink is among the Indonesian population. Coffee has relatively high levels of caffeine, and continued excessive consumption can increase the risk of developing several types of diseases, such as hypertension, heart disease, and stroke. According to the Food and Drug Monitoring Agency (BPOM), the maximum limit for caffeine consumption in food and drinks is 150 mg per day and 50 mg per serving. Excessive and continuous coffee consumption can increase the risk of developing certain diseases such as hypertension, heart disease and stroke. This research aimed to determine the secondary metabolite content of robusta coffee leaves and arabica coffee leaves and to determine the caffeine content in robusta coffee leaves and arabica coffee leaves using high-performance liquid chromatography. The stages of this research include processing plant material, characterisation, making ethanol extract, phytochemical screening, and determining caffeine content in robusta coffee leaf extract and Arabica coffee leaves using high-performance liquid chromatography. Extracts from Robusta coffee leaves and Arabica coffee leaves are made using the maceration method using 96% ethanol. The resulting extract was then concentrated using a rotary evaporator, and qualitative testing of caffeine was carried out using the Parry method. Caffeine levels were determined using high-performance liquid chromatography, using the regression equation y = ax+b, where y is the area, a= 49.668, and b= - 16.536. The caffeine content in Robusta coffee leaf extract was measured at around 51.42916 mg/g, while Arabica coffee leaf extract had a caffeine content of around 29.97927 mg/g.
Uji Aktivitas Antibakteri Fraksi N-Heksan Kulit Bawang Merah (Allium cepa L.) Terhadap Bakteri Streptococcus mutans Ika Yeni Siahaan; Haris Munandar Nasution; Muhammad Amin Nasution; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.258

Abstract

Caries, or cavities, is a disease caused by damage to the enamel layer caused by the activity of bacteria in the mouth, one of which is the Streptococcus mutans bacterium. One of the plants that is useful as an antibacterial is the red onion (Allium cepa L.). The objective of this research was to determine the content of secondary metabolites in shallot skin and the antibacterial activity of the n-hexane and ethyl acetate fractions of shallot skin against Streptococcus mutansbacteria. An antibacterial activity test was carried out using the Kirby-Bauer diffusion method using paper discs. Empty Kirby-Baurer disks were dipped for 15 minutes into each solution of the n-hexane fraction and ethyl acetate fraction of shallot skin in various concentrations of 10%, 30%, 50%, and 70%. The positive controls used were amoxicillin disks, and the negative controls used DMSO. The content of secondary metabolites in the ethyl acetate fraction of shallot skins, which are semi-polar, is alkaloids, flavanoids, and tannins. Meanwhile, the n-hexane fraction of shallot skin contains nonpolar compounds, namely saponins and steroids or triterpenoids. The antibacterial test results of the ethyl acetate fraction of shallot skin obtained the diameter of inhibition at a concentration of 10% (7.33 ± 1.52), a concentration of 30% (9.67 ± 1.52), a concentration of 50% (13.33 ± 1, 52), and a 70% concentration (15.67 ± 1.52). While the n-hexane fraction of shallot skin obtained the diameter of the inhibition zone at a concentration of 10% (1.00 ± 1.00), a concentration of 30% (8.67 ± 1.52), a concentration of 50% (9.67 ± 1.52), and a 70% concentration (11.33 ± 1.52). The n-hexane fraction and the ethyl acetate fraction of shallot skin (Allium cepa L.) had antibacterial activity against Streptococcus mutans, with the best inhibition being the ethyl acetate fraction at a concentration of 70% classified as intermediate.
Uji aktivitas antibakteri kombinasi ekstrak kulit dan biji Pepaya (Carica papaya L.) terhadap bakteri Staphylococcus aureus dan Escherichia coli Indra Ginting; Singgar Ni Rudang; Muhammad Andry; Mayang Sari; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.262

Abstract

Background;; Infectious diseases suffered by many people include Enterobacter infection from E.coli and skin infections due to S. aureus. One of the plants that have antibacterial properties is papaya like seeds and skin. Objekctives; The purpose of this study was to determine the activity of papaya skin and Seed (Carica papaya L.) extracts against S. aureus and E.coli. Method; The study used experimental method. The extraction used was maceration with ethanol 80%, 60% solvent. 40% and 20%. Antibacterial Activity Test using disc diffusion method and phytochemical screening test on papaya skin extract (Carica papaya L). Result; The results of screening tests on papaya skin extract (Carica papaya L) were positive for alkaloids, saponins, tannins, flavonoids and steroids. The results obtained at 60% ethanol showed that the combined extract of papaya skin and seeds (Carica papaya L) on S. aureus with concentrations (20:80) - (80:20) was 11.9 mm - 15.6 mm. In E. coli with a concentration (20:80) - (80:20) of 9.7 mm - 14.9 mm. Conclusion; The conclusions from the results of research on the combination of papaya skin and papaya seeds (Carica papaya L) of various concentrations inhibited S.aureus bacteria more than E.coli bacteria.
Penetapan kadar fenolik total ekstrak etanol, fraksi etil asetat dan n-heksan daun kopi robusta (Coffea canephora Pierre ex A. Froehner) dengan metode spektrofotometri Uv-Vis Yulia Nanda Putri; Muhammad Amin Nasution; Ridwanto Ridwanto; Anny Sartika Daulay
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.301

Abstract

Phenolic compounds have various biological effects, such as antioxidant activity, can reduce the risk of cancer, coronary heart disease, stroke and other neurodegenerative diseases. Robusta coffee leaves (Coffea canephora Pierre ex A. Froehner) have activity as antioxidants because they contain abundant phenolic compounds. This study aims to determine the ratio of total phenolic levels between ethanol extract, ethyl acetate fraction and n-hexane fraction from robusta coffee leaves. In this study, the first step taken was a characterization test on simplicial powder and robusta coffee leaves macerated with 70% ethanol solvent. The maserat obtained is further fractionated with n-hexane and ethyl acetate. Followed by phytochemical screening on coffee leaf samples. Furthermore, the extract, n-hexane fraction and ethyl acetate determined total phenolic levels using visible spectrophotometry at a wavelength of 749 nm. Determination of total phenolic levels using the Folin-Ciocalteu method with gallic acid standards. Total phenolic levels are expressed in mg gallic acid equivalent (GAE) per gram of simplicial. The results showed that 70% ethanol extract of robusta coffee leaves had a total phenolic content of 25.9438± 0.0889 mg GAE/g. From the fractionation results show that the ethyl acetate fraction of robusta coffee leaves has a greater total phenolic content compared to the n-hexan fraction of 28.048 ± 0.3692 mg GAE / g and followed by the n-hexane fraction of 15.5231 ± 0.7213mg GAE / g. This is because the fractionation method can increase the desired compound content by removing or separating unwanted compounds, thus making the compound results in the use of fractions purer.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Ekstrak Salep Ubi Jalar Ungu (Ipomoea Batatas (L.)) Lamk terhadap Bakteri Staphylococcus Aureus pada Penyembuhan Penyakit Luka Bernanah niswa, khairun; Dalimunthe, Gabena Indrayani; Nasution, Haris Munandar; Nasution, Muhammad Amin
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 2 (2024): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i2.2799

Abstract

Ubi jalar ungu jenis (Ipomoea batatas (L.)) Lamk ubi yang disebabkan oleh adanya pigmen ungu antosianin yang menyebar dari bagian kulit sampai dengan daging ubinya. Antosianin yang dapat berfungsi sebagai antioksidan memiliki aktivitas sebagai antibakteri. Tujuan penelitian untuk mengetahui apakah ekstrak etanol ubi jalar ungu (Ipomoea batatas (L.)) Lamk dapat dijadikan formulasi dapat dijadikan sebagai sediaan salep dan Untuk mengetahui aktivitas antibakteri sediaan salep ubi jalar ungu (Ipomoea batatas (L.)) Lamk terhadap bakteri Stapylococcus aureus. Metode penelitian ini meliputi: karakterisasi simplisia ubi jalar ungu, pembuatan ekstrak etanol ubi jalar ungu secara maserasi dengan pelarut etanol 96%, skrining fitokimia, uji aktivitas antibakteri ekstrak dan sediaan ubi jalar ungu terhadap bakteri Staphylococcus aureus dengan metode cakram dan sumuran, formulasi dan uji aktivitas antibakteri sediaan salep terhadap bakteri Staphylococcus aureus berbagai konsentrasi, dan evaluasi sediaan (pemeriksaan organoleptis, homogenitas, penentuan pH, stabilitas fisik, daya sebar, daya lekat dan uji iritasi sediaan). Berdasarkan hasil penelitian skrining fitokomia serbuk ubi jalar ungu yang memiliki senyawa aktif flavonoid, saponin, steroid, glikosida dan ekstrak memiliki senyawa aktif flavonoid, saponin, steroid. Ekstrak ubi jalar ungu (Ipomoea batatas (L.)) Lamk dapat dijdikan formulasi dalam sediaan bentuk salep yang baik dan memenuhi syarat mutu uji evaluasi organoleptis, pH, daya lekat, daya sebar, homogenitas, stabilitas fisik dan iritasi. Sediaan salep ubi jalar ungu memiliki aktivitas sebagai antibakteri Staphylococcus aureus dengan daya hambat (KUJU 20%) diameter 10,9 mm, (KUJU 25%) 15 mm, (KUJU 30%) 15,9 mm memiliki daya hambat paling tinggi
Formulasi Tablet Hisap Serbuk Buah Rimbang (Solanum Torvum Sw) menggunakan Metode Granulasi Kering dengan Variasi Bahan Pemanis Purba, Juvantri Fablo; Lubis, Minda Sari; Rafita Yuniarti; Nasution, Muhammad Amin
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 2 (2024): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i2.2800

Abstract

Buah rimbang (solanum torvum sw) memiliki manfaat sebagai antioksidan, mencegah diabetes, mengatasi masalah pencernaan, meningkatkan sistem kekebalan tubuh, mencegah kanker, merawat fungsi jantung, merawat kesehatan kulit, mengatasi peradangan, obat untuk infeksi bakteri, memperlancar peredaran darah, kesehatan mata dan buah rimbang dapat menjadi tabir surya alami. Tablet hisap banyak di kembangkan dalam industri farmasi karena kelebihan yang lebih mudah diterima oleh pasien terutama pada anak-anak, bentuknya yang menarik seperti permen serta praktis dalam penggunannya. Tujuan penelitian ini untuk mengetahui serbuk buah rimbang dengan variasi bahan pemanis memiliki sifat granulasi yang baik dan untuk mengetahui sediaan tablet serbuk buah rimbang memenuhi syarat sebagai sediaan tablet hisap. Metode yang digunakan pada proses pembuatan tablet ini adalah proses pembuatan tablet hisap dengan menggunakan metode granulasi kering yang di dalamnya terdapat uji mutu karakteristik fisik granul dan setelah menjadi tablet dilakukan uji mutu karakteristik fisik sediaan tablet dan selanjutnya dilakukan uji tingkat kesukaan pada para panelis terhadap perbandingan konsentrasi variasi bahan pemanis Hasil penelitian dari mutu karakteristik fisik granul yaitu uji waktu alir, sudut diam, dan indeks tap mendapatkan hasil yang memenuhi syarat serta mutu sediaan tablet yang meliputi uji keseragaman bobot, kerapuhan, kekerasan, dan waktu hancur juga memenuhi syarat pada tiap formula dan saat dilakukan uji kesukaan. Para panelis menyukai tablet hisap Formula 1 yaitu dengan perbandingan. Manitol : Xylitol (1:1). Kombinasi pemanis yang disukai para panelis adalah komninasi 1:1 yang mana Manitol dan Xylitol memiliki kombinasi rasa yang pas dimulut para panelis.
ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY Khairani, Tetty Noverita; Fitri, Khairani; Andry, Muhammad; Nasution, Muhammad Amin
Jurnal Farmasi Sains dan Praktis Vol 9 No 3 (September-December 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i3.7542

Abstract

Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The purpose of this study is to assess the efficacy of deodorant spray and basil leaf extract on bacterial activity, as well as the optimal dose of deodorant spray for lowering the activity of these bacteria. Method the research was conducted experimentally, testing antibacterial activity using agar diffusion. The results of the deodorant spray preparation test showed that the preparation was homogeneous, organoleptically brown in color, had a distinctive smell, and had a liquid texture; the pH test results met the requirements for deodorant spray 4.5-6.5. The average diameter of the inhibition zones produced from each preparation were Staphylococcus epidermidis bacteria, positive control 7 mm, negative control 10.1 mm; formula 5% 12.3 mm; formula 10% 13.3 mm; formula 15% 12.7 mm maximum concentration in inhibiting bacteria is formula 10% by 13.3 mm, while the bacteria Staphylococcus Aureus positive control 13 mm, negative control 11.2 mm, 5% formula 13.1 mm; formula 10% 13.4 mm; 15% formula 13.9 mm maximum concentration in inhibiting bacteria is 15% formula 13.9 mm. Based on the inhibitory zone created by 10% basil leaf ethanol extract, Staphylococcus epidermidis bacteria had a 13.3 mm clean zone and Staphylococcus aureus bacteria had a 26.5 mm clean zone.
Co-Authors Abadi, Hafizhatul Ade Shindy F Br Sembiring Ade Sumiardi Adek Chan Afra, Mauliza Anggi, Reza Destri Anny Sartika Daulay Anny Sartika Daulay Apmarja, Sarah Utami Arfiani Arifin Aris Ma'ruf Aryunda, Divia Asparyzha, Rhyzha Asyifa, Cut Nella Asyrun Alkhairi Lubis Awanis, Safirah Cut Nella Asyifa Didi Nurhadi Illian Dwiyarina Margarisa Fahma Shufyani Faisal, Hendri Fajar Fakri Fira Safitri Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Hari Hariadi Haris Munandar Nasution Hasibuan, Supia Indah Hendra Jaya Hendri Faisal Hendri Faisal Hendri Faisal Hindri Syahputri Humaira, Yara Humaira, Zaura Ika Julianti Tambunan Ika Yeni Siahaan Indra Ginting Iryana, Mirdha Isti Dwi Pruschia Januri, Muhammad Rizal Jefri Naldi Khairani Fitri Khairani, Tetty Noverita Leni Halimatusyadiah Lestari, Seri Ligo, Azzura Lilik Septiana Lubis, Minda Sari Luthvia, Luthvia M. Fariz Fadillah M. Fariz Fadillah M. Pandapotan Nasution Mambang, D Elysa Putri Manik, Umi Chairani Mayang Sari Melia Sari Melia Sari Melia Sari, Melia Mirdha Iryana Muhammad Alifza Muhammad Andry Muhammad Yunus Muhammad Yunus Muhammad Yunus Muhni, Akmal Mutia Muhardiyanti Nazirah, Nazirah Naziyah, Syifa Nia Novranda Pertiwi Nidia Rizka Niswa, Khairun Nurul Aulia Octania, Adelia Dwi Pradita, Diding Pricella Ginting Purba, Juvantri Fablo Putri , Adilla Rida Evalina Tarigan Ridwanto Ridwanto Rinda Sari, Sylvi Rudang, Singgar Ni Rumanti, Ruth Mayana Sahliah Sahliah, Sahliah Sandrina, Syura Sari, Syilvi Rinda Selfia Lestary Shodikin, Marwan Ali Simanjuntak, Monica Nelly Siregar , Runisya Maugin Utami Siregar, Rina Paramitha Siska Dwi Anggraeni Suseno Amien Syafira, Nona Tanjung, M. Fadli Tetty Noverita Khairani Tia Nazilla Tri Damaiyanti Vannissa Andriani Irawan Winata, Hanafis Sastra Yadi, Hervi Yanti, Rahma Yayuk Putri Rahayu Yulia Nanda Putri Yuniarti , Rafita Yuniarti, Rafita Yusep Ikrawan Zahara, Fitria Siti Zhafirah, Rana Zikra Maqfirah Ziza Putri Aisyia Fauzi Zulmai Rani