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All Journal SUPREMASI: Jurnal Pemikiran, Penelitian Ilmu-Ilmu Sosial, Hukum dan Pengajarannya Al-Risalah : Jurnal Imu Syariah dan Hukum Journal of Agromedicine and Medical Sciences Jurnal Pengabdian UntukMu NegeRI Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA Jurnal Biotek Jurnal Dunia Farmasi Jurnal Ilmiah Manusia dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Kesehatan Tambusai Jurnal EduHealth Acta Islamica Counsenesia: Counselling Research and Applications Jurnal Farmasi Sains dan Praktis FARMASAINKES Journal of Pharmaceutical and Sciences. Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara
Muhammad Amin Nasution
Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Al Washliyah, Medan, 20147, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Antibacterial Activity of Foot Spray Preparations Extract of Jeruk Purut Leaves (Citrus Hystrix) and Robusta Coffee Leaves (Coffea canephora) Against Staphylococcus epidermidis Lestari, Seri; Nasution, Muhammad Amin; Dalimunthe, Gabena indrayani; Lubis, Minda Sari
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8736

Abstract

A problem that is often found in Indonesia, especially on the feet and causes many people to lack self-confidence, is smelly feet. This odor is caused by bacteria on the skin and inside shoes. Bacteria like Staphylococcus epidermidis produce an unpleasant smell by degrading leucine from sweat, leading to the formation of isovaleric acid, which emits a foul odor. This issue can be addressed using plant materials such as jeruk purut leaves (Citrus hystrix) and robusta coffee leaves (Coffea canephora). This research uses an experimental method. Jeruk purut leaves and robusta coffee leaves are extracted through maceration and then formulated into a foot spray with extract concentrations of 1.5%, 2%, and 2.5%. The evaluation results indicate that the foot spray formulation meets the stability test parameters, including organoleptic properties and pH. In terms of hedonic testing, panelists preferred Formula 1, and no formula caused skin irritation. Antibacterial testing of all formulations showed strong antibacterial activity, with inhibition zone diameters of 11.9 mm for Formula 1 (1.5% concentration), 12.4 mm for Formula 2 (2% concentration), and 12.8 mm for Formula 3 (2.5% concentration) against Staphylococcus epidermidis. Statistical analysis using One-Way ANOVA showed that the antibacterial activity of the foot spray in inhibiting bacterial growth was significant at a 0.005 level, with a probability value (significance) of 0.00 < 0.05, indicating that the antibacterial activity of the foot spray can affect the growth of Staphylococcus epidermidis.
Penyuluhan Penyakit Diabetes Melitus Dan Pemeriksaan Kesehatan Di Dusun I Desa Kolam Kecamatan Percut Sei Tuan Nasution, Muhammad Amin; Nia Novranda Pertiwi; Hindri Syahputri
Jurnal Pengabdian UntukMu NegeRI Vol. 6 No. 2 (2022): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v6i2.4017

Abstract

Kesehatan merupakan faktor penting dalam kehidupan seseorang agar dapat beraktivitas setiap harinya. Kesibukan serta sarana transportasi yang memadai untuk menunjang aktivitas sehari-hari menyebabkan sebagian orang kurang melakukan gerakan fisik dan berolahraga, sehingga mengakibatkan proses metabolisme tubuh menjadi terganggu, hal tersebut merupakan sebagian dari faktor yang mendukung terjadinya penyakit diabetes melitus. Diabetes Melitus (DM) merupakan penyakit gangguan metabolik menahun dan juga menjadi masalah kesehatan di masyarakat paling utama karena komplikasinya bersifat jangka pendek dan jangka panjang. Oleh karena itu perlu diadakannya penyuluhan dan edukasi kepada masyarakat terkhusus di dusun I desa kolam terkait dengan penyakit diabetes melitus dengan tujuan memberikan tambahan pengetahuan mengenai diabetes melitus baik cara pencegahannya dan penanganannya bagi yang telah terkena diabetes melitus. Metode yang digunakan dalam kegiatan ini dengan memberikan penyuluhan berupa ceramah interaktif dalam bentuk presentase kepada masyarakat. Selain itu, pada acara ini juga dilakukan pemeriksaan Kadar Gula Darah (KGD) gratis bagi masyarakat. Dari hasil kegiatan pengabdian yang dilakukan sebanyak 24 orang peserta diperoleh 7 orang memiliki kadar gula darah diatas normal > 200 mg/dl dan sebanyak 17 orang kadar gula darahnya normal < 200 mg/dl. Kata Kunci: Kesehatan, Diebetes Melitus, Penyuluhan, KGD
Uji kadar total polifenol buah asam kandis (Garcinia xanthochymus Hook.f.ex T.Anderson) dengan metode spektrofotometri UV-VIS dan LCMS Winata, Hanafis Sastra; Faisal, Hendri; Andry, Muhammad; Naziyah, Syifa; Nasution, Muhammad Amin
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.320

Abstract

Background: Kandis tamarind has various activities, such as antioxidant, cytotoxic, anti-inflammatory, and antimicrobial. This study aimed to determine the total polyphenol content of kandis acid fruit and the types of phenolic compounds contained in kandis acid fruit. This type of research was experimental, using 70% ethanol solvent. The research method used was a polyphenol qualitative test, UV-Vis spectrophotometry, and LC-MS. The results of qualitative measurements showed that the samples contained polyphenolic compounds. The results of the polyphenol test on the kandis acid fruit sample on 1% FeCl3 reagent and diazo reagent got positive results, while the Millon reagent got negative results. The study's results show that the determination of the levels of polyphenol content in kandis acid fruit extract was measured using UV-VIS spectrophotometry by adhering to the working principle of Folin-Ciocalteau. The proof of polyphenol content used the Folin-Ciocalteau reagent because this reagent can react with a group of polyphenolic compounds to form a concentrated solution whose absorbance can be measured. The higher the sample concentration, the higher the absorbance value. The results of determining the polyphenol content of the kandis acid fruit extract using uv-vis spectrophotometry had a polyphenol compound component of 61.1015 mg GAE/g sample. The results of the LC-MS analysis for the highest phenolic compound, namely the type of vanillic acid, amounted to 14.21%.  
Isolasi senyawa flavonoid dari daun bakung (Crinum asiaticum L.) Abadi, Hafizhatul; Rumanti, Ruth Mayana; Andry, Muhammad; Nasution, Muhammad Amin
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.322

Abstract

Introduction Sprains and fractured bones are treated with spider lily leaves (Crinum asiaticum L.). Alkaloids, flavonoids, tannins, steroids, and triterpenoids are among the chemical components found in spider lily leaves. The most significant phytochemicals in plants with wide biological advantages for humans are bioactive flavonoids. The purpose of: The study aimed to isolate flavonoid components from spider lily leaves. Methods: This study was descriptive, using the following steps: plant material collection and preparation, sample processing, simplicia characterization, extract preparation, phytochemical screening, hydrolysis, fractionation, analysis using paper chromatography (KKt), and compound isolation using preparative paper chromatography. The isolates were tested for purity using one-way and two-way KKt, and they were identified using UV-Vis spectrophotometry with a shear reagent. The results: The results of the characterization showed that the water content was 7.21%, the water-soluble extract was 11.21%, the ethanol-soluble extract was 9.23%, the total ash content was 1.99%, and the acid-insoluble ash content was 0.81%. The screening findings indicated the presence of flavonoid chemicals. The KKt analysis results revealed that the best mobile phase was 5% acetic acid with ammonia vapor specks, and the preparative KKt isolation results yielded a single blue isolate, which was then identified by UV-Vis spectrophotometry using a shear reagent, resulting in maximum wavelength absorption (max) at band II of 253nm, presumably identifying the isoflavone group of flavonoids. Conclusion: The conclusion showed the ethyl acetate fraction of spider lily leaves could be separated using paper chromatography and that identification by spectrophotometry UV-Vis using a shear reagent wasolate, which was assumed to be an isoflavone group component.
Skrining fitokimia dan uji aktivitas antioksidan ekstrak metanol daun salam (Syzygium polyanthum (Wight.) Walp.) dari Gampong Bunot, Pidie Jaya dengan metode DPPH Nazirah, Nazirah; Nasution, Muhammad Amin; Ridwanto, Ridwanto; Nasution, Haris Munandar
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.376

Abstract

Antioxidants are compounds that can delay, slow down, or inhibit the oxidation reaction of food or medicine. Antioxidants include electron-donor compounds that work by donating an electron to compounds that are free radicals so that radical activity is inhibited. One of the plants that can be used as a source of natural antioxidants is salam leaf (Syzygium polyanthum (Wight.) Walp). Salam leaves contain secondary metabolite compounds, including alkaloids, tannins, saponins, steroids, triterpenoids, and flavonoids, which act as antioxidants. The study aimed to determine whether the methanol extract of salam leaves (Syzygium polyanthum (Wight.) Walp.), which grows in Gampong Bunot, Pidie Jaya, contains secondary metabolites and has activity as an antioxidant. This research was conducted experimentally, where the sample used was salam leaves. The stages of this research included the processing of plant materials, preparation of methanol extract of salam leaves, characterization examination, phytochemical screening, and antioxidant activity test of methanol extract of salam leaves using the DPPH method. Salam leaf extract was prepared by maceration method using methanol solvent obtained and concentrated with a rotary evaporator, then the phytochemical screening test and the antioxidant activity test of the methanol extract of salam leaves were carried out using the DPPH method (1,1 diphenyl-2-picrylhidrazil) at a wavelength of 516 nm and vitamin C as a comparison. Based on the results of the phytochemical screening test, there were differences in secondary metabolites in the methanol extract of salam leaves grown in Gampong Bunot, Pidie Jaya, including alkaloids, flavonoids, saponins, tannins, steroids, and glycosides. The results of the antioxidant activity test of the methanol extract of salam leaves obtained the IC value50 of 25.68 µg/ml and the IC value50 Vitamin C of 4.537 µg/ml in the second category is very strong.  
Skrining fitokimia dan uji aktivitas antioksidan dari ekstrak etanol daun kedondong (Spondias dulcis Soland. ex Forst. fil) dengan metode DPPH Yanti, Rahma; Nasution, Muhammad Amin; Ridwanto, Ridwanto; Nasution, Haris Munandar
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.377

Abstract

Antioxidants are compounds that can ward off free radicals and prevent damage caused by free radicals. Free radicals are unstable and reactive molecules formed from unpaired electrons that can cause damage to the skin. To protect the body's skin from free radicals, it can be overcome by using an antioxidant compound. One is kedondong leaves, which contain polyphenolic compounds known to have antibacterial and antioxidant properties. This study aimed to conduct phytochemical screening and determine the antioxidant activity of ethanol extract of kedondong leaves with the DPPH method. This study was conducted experimentally, where the sample used was kedondong leaves. The stages of research include sample preparation, plant identification, making simplisia, phytochemical screening on kedondong leaf extract and simplisia, then antioxidant activity tests were carried out on kedondong leaf ethanol extract using the DPPH method (1,1-diphenyl -2-picrylhydrazil) at a maximum wavelength of 516 nm, as a positive control vitamin C was used. The research on phytochemical screening showed that ethanol extract of kedondong leaves contains secondary metabolite compounds, namely tannins, saponins, alkaloids, flavonoids, steroids, triterpenoids, and glycosides. In testing, the antioxidant activity of ethanol extract of kedondong leaves showed very strong antioxidant activity with an IC50 of 44.855 μg/ml, and vitamin C had very strong antioxidant activity with an IC50 of 4.44 μg/ml.
Formulasi sediaan pelembab bibir mengandung ekstrak kulit buah pisang raja (Musa paradisiaca L) Siregar , Runisya Maugin Utami; Yuniarti, Rafita; Lubis, Minda Sari; Nasution, Muhammad Amin
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.674

Abstract

Lip balm is a care product that can keep your lips moist, which is a type of ointment used to treat dry and chapped lips. The benefit of using lip balm for lips is to regulate lip moisture. Lip balms are generally clear or colorless, although recently colored variants have also been created. To find out whether the extract of plantain peel (Musa paradisiaca L) can be formulated in the form of lip balm preparations. The purpose of this study was to determine whether lip balm preparations could be used as moisturizers. To find out lip balm preparations well made and of good physical quality. This research method is experimental. Collection of plants was carried out purposively, ie without comparison with other areas. The sample used was the skin of fresh ripe plantains obtained from the Simpang Limun market in Medan. This study included quality inspection preparations, moisture effectiveness test preparations, irritation tests on formulations and hedonic tests on variations in preparations made. The results of this study indicate that extracts of plantain peel (Musa paradisiaca L) with concentrations of 1%, 3%, 5%, 10%, and 15% can be formulated in the form of lip balm preparations. Formula 5 with a concentration of 15% showed the best lip balm preparation by fulfilling the requirements for physical quality, effectiveness and safety. With a preference value of 5 (like very much), has a melting point of 57'C and has a pH of 5.9 so it does not cause skin irritation and is stable at room temperature storage for 28 days. Lip balm preparations made using cocoa butter base are safe to use and meet the standards..
Penetapan kadar flavonoid total dan aktivitas antioksidan ekstrak etanol, fraksi n-heksan, etil asetat daun senggani (Melastoma candidum D.Don) secara spektrofotometri visibel Apmarja, Sarah Utami; Nasution, Muhammad Amin; Nasution , Haris Munandar; Yuniarti , Rafita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.797

Abstract

Medicinal plants are natural sources that have antioxidant activity, characterized by the content of phenolic and flavonoid components in reducing free radicals which depends on the number of hydroxyl groups in their molecular structure. One of the plants that contain flavonoid compounds which have antioxidant activity is senggani leaves (Melastoma candidum D.Don). This research aimed to determine the chemical compounds contained in the ethanol extract, to determine the total flavonoid value of the ethanol extract, the ethyl acetate fraction and the n-hexane fraction and to determine the antioxidant activity of the ethanol extract, the ethyl acetate fraction and n-hexane fraction. The stages of this research include processing plant materials, making ethanol extract, making ethyl acetate fraction and n-hexane fraction, characterization examination, phytochemical screening, and determining the total flavonoid content of ethanol extract, ethyl acetate fraction and n-hexane fraction of senggani leaves using Visible and Spectrophotometric methods. Determination of the antioxidant activity of ethanol extract, ethyl acetate fraction, and n-hexane fraction using different techniques, namely DPPH with ABTS. The results of phytochemical screening on simplicia powder and ethanol extract contained chemical compound groups such as alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides. The results of determining the total flavonoid content in the ethanol extract of senggani leaves were 44.7805 ± 0.176606439 mgQE/g; In the ethyl acetate fraction, it was 48.421 ± 0 mgQE/g, and in the n-hexane fraction it was 31.491 ± 0.091844121 mgQE/g. The results of antioxidant activity using the DPPH method obtained an IC₅₀ value for the ethanol extract of 12.51 (μg/ml); in the ethyl acetate fraction of 9.42 (μg/ml); in the n-hexane fraction, it was 40.45 (μg/ml), and in the vitamin C standard it was 4.32 (μg/ml). Antioxidant results using the ABTS method obtained an IC₅₀ value for the ethanol extract of 8.21(μg/ml); in the ethyl acetate fraction of 5.93(μg/ml); in the n-hexane fraction, it was 23.35(μg/ml), and in the vitamin C odor it was 2.65(μg/ml).
KEWAJIBAN ORANG TUA DALAM PENDIDIKAN AGAMA ANAK: PERSPEKTIF HUKUM ISLAM Tanjung, M. Fadli; Sahliah, Sahliah; Nasution, Muhammad Amin
SUPREMASI: Jurnal Pemikiran, Penelitian Ilmu-ilmu Sosial, Hukum dan Pengajarannya Volume 20, Nomor 2 (Oktober 2025)
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/supremasi.v20i2.76817

Abstract

Adanya masalah serius dalam pola asuh dan pendidikan keluarga. Orang tua yang seharusnya menjadi teladan dalam menanamkan nilai-nilai kejujuran, kerja keras, dan keberkahan rezeki, justru memberikan legitimasi terhadap perilaku menyimpang. Kebanggaan orang tua terhadap anak yang memperoleh uang dari sumber haram memperlihatkan lemahnya kesadaran akan pentingnya keberkahan dalam nafkah, sekaligus mencerminkan adanya pergeseran orientasi hidup dari nilai moral ke nilai material. Penelitian ini bertujuan untuk memahami konsep kewajiban orang tua dalam memberikan ilmu agama kepada anak sesuai hukum Islam, mengidentifikasi realitas sosial yang terjadi di Desa Bagan Asahan, dan menganalisis upaya solusi untuk mengoptimalkan peran orang tua. Dari pembahasan ini, rumusan permasalahan adalah apa kewajiban orang tua terhadap anak, bagaimana orang tua di Desa Bagan Asahan memahami kewajiban memberikan ilmu agama kepada anak, bagaimana kewajiban orang tua dalam memberikan ilmu agama kepada anak di Desa Bagan Asahan dipandang dari hukum Islam dan apa konsekuensi orang tua jika tidak memenuhi kewajibannya. Metode penelitian yang digunakan adalah penelitian kualitatif deskriptif dengan studi kasus, melalui wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa sebagian besar orang tua di Desa Bagan Asahan belum memberikan pengetahuan agama secara optimal kepada anak-anak karena kesibukan ekonomi dan rendahnya pemahaman beragama. Dampaknya terlihat dari kurangnya pemahaman agama seperti moral anak yang lemah, dan meningkatnya perilaku menyimpang. Hukum Islam menekankan bahwa orang tua berkewajiban untuk mendidik anak sejak dini dalam ilmu agama dan moral, dan kelalaian dalam kewajiban ini adalah dosa.
Co-Authors Abadi, Hafizhatul Ade Shindy F Br Sembiring Ade Sumiardi Adek Chan Anggi, Reza Destri Anny Sartika Daulay Anny Sartika Daulay Apmarja, Sarah Utami Arfiani Arifin Aris Ma'ruf Aryunda, Divia Asparyzha, Rhyzha Asyrun Alkhairi Lubis Awanis, Safirah Cut Nella Asyifa Didi Nurhadi Illian Dwiyarina Margarisa Fahma Shufyani Faisal, Hendri Fajar Fakri Fira Safitri Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Hari Hariadi Haris Munandar Nasution Hasibuan, Supia Indah Hendra Jaya Hendri Faisal Hendri Faisal Hendri Faisal Hindri Syahputri Ika Julianti Tambunan Ika Yeni Siahaan Indra Ginting Isti Dwi Pruschia Januri, Muhammad Rizal Jefri Naldi Khairani Fitri Khairani, Tetty Noverita Leni Halimatusyadiah Lestari, Seri Ligo, Azzura Lilik Septiana Lubis, Minda Sari Luthvia, Luthvia M. Fariz Fadillah M. Fariz Fadillah M. Pandapotan Nasution Mambang, D Elysa Putri Manik, Umi Chairani Mayang Sari Melia Sari Melia Sari Melia Sari, Melia Mirdha Iryana Muhammad Alifza Muhammad Andry Muhammad Yunus Muhammad Yunus Muhammad Yunus Mutia Muhardiyanti Nazirah, Nazirah Naziyah, Syifa Nia Novranda Pertiwi Nidia Rizka Niswa, Khairun Nurul Aulia Octania, Adelia Dwi Pradita, Diding Pricella Ginting Purba, Juvantri Fablo Putri , Adilla Rafita Yuniarti Rezaldi, Firman Rida Evalina Tarigan Ridwanto Ridwanto Rinda Sari, Sylvi Rudang, Singgar Ni Rumanti, Ruth Mayana Sahliah Sahliah, Sahliah Sari, Syilvi Rinda Selfia Lestary Shodikin, Marwan Ali Simanjuntak, Monica Nelly Siregar , Runisya Maugin Utami Siregar, Rina Paramitha Siska Dwi Anggraeni Suseno Amien Syafira, Nona Tanjung, M. Fadli Tetty Noverita Khairani Tia Nazilla Tri Damaiyanti Vannissa Andriani Irawan Winata, Hanafis Sastra Yadi, Hervi Yanti, Rahma Yayuk Putri Rahayu Yulia Nanda Putri Yuniarti , Rafita Yuniarti, Rafita Yusep Ikrawan Zahara, Fitria Siti Zhafirah, Rana Zikra Maqfirah Ziza Putri Aisyia Fauzi Zulmai Rani