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All Journal SUPREMASI: Jurnal Pemikiran, Penelitian Ilmu-Ilmu Sosial, Hukum dan Pengajarannya Al-Risalah : Jurnal Imu Syariah dan Hukum Journal of Agromedicine and Medical Sciences Jurnal Pengabdian UntukMu NegeRI Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA Jurnal Biotek Jurnal Dunia Farmasi Jurnal Ilmiah Manusia dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Kesehatan Tambusai Jurnal EduHealth Acta Islamica Counsenesia: Counselling Research and Applications Jurnal Farmasi Sains dan Praktis FARMASAINKES Journal of Pharmaceutical and Sciences. Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara
Muhammad Amin Nasution
Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Al Washliyah, Medan, 20147, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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DAMPAK GAME ONLINE TERHADAP PERILAKU SOSIAL SISWA SMPN 1 PUNCAK SORIK MARAPI: SEBUAH ANALISIS FENOMENOLOGIS [IMPACT OF ONLINE GAMES ON SOCIAL BEHAVIOR OF SMPN 1 PUNCAK SORIK MARAPI STUDENTS: A PHENOMENOLOGICAL ANALYSIS] Nasution, Muhammad Amin; Januri, Muhammad Rizal; Shodikin, Marwan Ali
Acta Islamica Counsenesia: Counselling Research and Applications Vol 2, No 2 (2022): Desember
Publisher : Perkumpulan Ahli Bimbingan Konseling Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59027/aiccra.v2i2.194

Abstract

Adolescence is a period of transition between children and adults, at this time teenagers are also known as periods of difficulty. The current era of technology has received a lot of attention from the wider community, one of which is the problem of online games. This research is motivated by the existence of very rapid technological developments that cause students to experience changes in social behavior. The basic purpose of this study is to explain the positive and negative impacts of online games on the social behavior of students at SMP Negeri 1 Puncak Sorik Marapi. The research method used is a qualitative method. The approach used by the researcher is a phenomenological approach. This study will focus on the impact of online games on students' social behavior. The results of this study are the negative impact of students who are considered addicted to online games, of course, very diverse including students sometimes speak impolite and polite, some students also forget time for school because of the fun of playing, students also often spend time playing games at school, stealing time. during study hours so that it has an impact on social change which often forgets the surrounding environment, while the positive impact of online games on the social behavior of SMP Negeri 1 Puncak Sorik Marapi students is in the form of adding relationships, means of refreshing, collaborating, and students can express their emotions through playing online games.
Penyuluhan Pentingnya Mengetahui Kadar Antibiotik Dalam Penggunaan Secara Bijak dan Efektif Pertiwi, Nia Novranda; Hindri Syahputri; Syilvi Rinda Sari; Muhammad Amin Nasution
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 2 (2025): April-Juni 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i2.11109

Abstract

Antibiotik merupakan salah satu obat yang sangat penting dalam dunia medis untuk mengobati infeksi yang disebabkan oleh bakteri. Namun, penggunaan antibiotik yang tidak bijak dan tanpa memperhatikan kadar atau dosis yang tepat dapat menyebabkan masalah kesehatan yang serius, termasuk resistensi antibiotik. Penyuluhan ini bertujuan untuk meningkatkan pengetahuan siswa kelas 6 Sekolah Dasar (SD) Yayasan Pendidikan Ar-Ridha, sebagai kelompok yang masih dalam tahap pembelajaran dan memiliki potensi untuk menerima edukasi sejak dini mengenai pentingnya mengetahui kadar antibiotik agar penggunaannya lebih tepat sasaran, aman, dan efektif. Kegiatan penyuluhan dilakukan dengan metode ceramah, diskusi dan tanya jawab. Penilaian terhadap keberhasilan kegiatan dilakuakan dengan menggunakan kuesioner. Hasil kuesioner menunjukkan ketertarikan peserta akan kegiatan sebesar 93, 35%, pemahaman terkait informasi kadar obat sebesar 85, 52%, dan pengetahuan peserta terhadap penggunaan antibiotik secara bijak dan efektif sebesar 90, 50%. Penyuluhan ini terbukti dapat meningkatkan pemahaman siswa tentang penyuluhan pentingnya mengetahui kadar antibiotic dalam penggunaan secara bijak dan efektif.
Pengaruh Perbedaan Metode Ekstraksi Maceration dan Microwave Assisted Extraction (MAE) Terhadap Penetapan Kadar Flavonoid Total Buah Ara (Ficus racemosa L.) Andry, Muhammad; Ligo, Azzura; Anggi, Reza Destri; Pradita, Diding; Luthvia, Luthvia; Nasution, Muhammad Amin; Pertiwi, Nia Novranda; Arifin, Arfiani
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.859

Abstract

Figs (Ficus racemosa L.) are an essential source of bioactive components such as phenols, terpenoids, flavonoids, and alkaloids with antioxidant properties. Two extraction methods are used to extract flavonoids from figs: conventional and non-conventional. This study aimed to determine the effect of different extraction methods—maceration and Microwave Assisted Extraction (MAE)—on the total flavonoid content in figs (Ficus racemosa L.). The research was conducted using a laboratory experimental method. The procedures included collecting and preparing plant materials, producing simplicia, evaluating simplicia characteristics, conducting phytochemical screening, preparing extracts, and determining total flavonoid content. The results showed that the maximum wavelength of quercetin was 438 nm, with a regression equation of Y = 0.0669x + 0.0084. The average absorbance values of fig extract using the maceration method were 0.216 with methanol, while the MAE method was 0.280 with methanol. The average percentage of flavonoid content using the maceration method was 0.1245% with methanol, while with the MAE method, it was 0.1623% with methanol. The total flavonoid content of fig extract using the maceration method was 1.2451 mgQE/g extract with methanol, while with the MAE method, it was 1.6238 mgQE/g extract with methanol. The study concluded that the highest total flavonoid content was found in the methanol extract obtained through MAE. This extract had a value of 1.6238 mgQE/g extract.
Pengaruh Metode Ekstraksi Daun Jarak Cina (Jatropha multifida L.) Secara Maserasi dan Microwave-Assisted Extraction (MAE) Terhadap Aktivitas Antijamur Pada Candida albicans Aryunda, Divia; Nasution, Muhammad Amin; Nasution, Haris Munandar; Pulungan , Ainil Fithri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.868

Abstract

Introduction: Indonesia possesses high biodiversity, including the Jatropha multifida L. plant, which contains secondary metabolites with potential antimicrobial properties. Traditionally, the leaves of Jatropha multifida have been used as herbal medicine, particularly for inhibiting the growth of microorganisms. Objective: This study aims to determine the total flavonoid content in the ethanol extract of Jatropha multifida leaves and to compare the effectiveness of two extraction methods, maceration and Microwave-Assisted Extraction (MAE), in inhibiting the growth of Candida albicans. Methods: The research stages included the characterization of the powdered simplicia, extraction of Jatropha multifida leaves using 96% ethanol by maceration and MAE methods, and phytochemical screening. The total flavonoid content was determined using UV-Vis spectrophotometry at a wavelength of 431 nm. Antifungal activity against Candida albicans was tested for each extract at specific concentrations. Results: The ethanol extract obtained through maceration showed a total flavonoid content of 34.7089 ± 0.1206 mg QE/g, while the MAE method yielded 32.1923 ± 0.1113 mg QE/g. The highest antifungal activity was observed in the MAE extract at a 75% concentration, producing an inhibition zone of 24.7 mm. The maceration extract at the same concentration produced an inhibition zone of 23.7 mm. As a positive control, 2% ketoconazole resulted in an inhibition zone of 31.4 mm. Conclusion: Although the maceration method produced a higher total flavonoid content, the extract obtained through the MAE method demonstrated more potent antifungal activity against Candida albicans at the same concentration.
Formulasi dan Uji Mutu Fisik Krim Antiperspirant dari Ekstrak Kunyit Putih (Curcuma zedoaria (Berg.) Roscoe) Syafira, Nona; Dalimunthe , Gabena Indrayani; Lubis, Minda Sari; Nasution, Muhammad Amin
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.916

Abstract

Background: Curcuma zedoaria (Berg.) Roscoe, commonly known as white turmeric, is a plant from the Zingiberaceae family that contains bioactive compounds such as curcumin, flavonoids, alkaloids, saponins, and tannins. These compounds have potential as natural antiperspirants due to their astringent and antimicrobial properties, which can reduce sweat production and prevent body odor. The use of synthetic antiperspirants containing aluminum chloride often causes skin irritation, highlighting the need for safer, natural alternatives. Objective: This study aims to formulate an antiperspirant cream using white turmeric (Curcuma zedoaria (Berg.) Roscoe) extract with good physical quality and to evaluate the effectiveness of various concentrations in inhibiting sweat production. Methods: This experimental study involved extracting white turmeric using 96% ethanol through maceration, followed by concentration with a rotary evaporator. The antiperspirant cream was formulated with varying extract concentrations. Physical quality evaluations included organoleptic testing, homogeneity, pH, stability, viscosity, adhesion, spreadability, cream type, as well as irritation and antiperspirant tests on volunteers. Results: Phytochemical screening showed that the white turmeric extract contains alkaloids, flavonoids, saponins, and tannins. The cream with a 17.5% extract concentration demonstrated the highest antiperspirant effectiveness compared to 7.5% and 12.5% concentrations. All formulations met physical quality standards, including pH (4.5–6.5), viscosity (2,700–23,020 cP), and 14-day stability without significant changes. Conclusion: The white turmeric-based antiperspirant cream met physical quality standards and exhibited significant antiperspirant effects, particularly at a 17.5% concentration. This study demonstrates the potential of white turmeric as a safe and effective natural active ingredient in antiperspirant formulations.
Retrospective Study Of Vitamin Purchases During The Pandemic In UMI FARMA Pharmacy Manik, Umi Chairani; Nasution, Muhammad Amin; Octania, Adelia Dwi
Indonesian Journal of Science and Pharmacy Vol. 1 No. 2 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i2.29

Abstract

In early 2020, the world was shocked by the outbreak of a new pneumonia that started in Wuhan, China, and then spread rapidly to more than 190 countries and territories. This outbreak was named coronavirus disease 2019 (COVID-19), which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SA RS-CoV-2). The spread of this disease has had a broad social and economic impact.The COVID-19 pandemic that has occurred since March 2020 has affected all aspects of life. The aim of the research is to determine the purchase of vitamins during the pandemic in July–December 2021 at the UMI FARMA Pharmacy. This research was conducted retrospectively. Data collection was obtained from recording several vitamin products purchased by patients. Data was obtained from the sales and purchases book at the UMI FARMA Pharmacy. The targeted output is purchasing vitamins during the pandemic in July–December 2021.
Antibactery Activity of Etyl Asetate Fraction of Etanol Extract of Pala Leaf (Myristica Fragrans) and Lidah Buaya Leaf (Aloe Vera) Against Streptococcus Mutans Awanis, Safirah; Mambang, D Elysa Putri; Yuniarti, Rafita; Nasution, Muhammad Amin
Indonesian Journal of Science and Pharmacy Vol. 2 No. 3 (2025): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v2i3.97

Abstract

Caries is a progressive chronic hard tissue disease of the teeth caused by the action of microorganisms. The bacteria that causes this disease is Streptococcus mutans. Nutmeg leaves (Myristica fragrans) and aloe vera leaves (Aloe vera) can potentially overcome diseases and health problems. This study was to determine the antibacterial activity of n-hexane fraction, ethyl acetate, ethanol extract of  nutmeg leaf and aloe vera leaf in Streptococcus mutans and to determine the effect of n-hexane fraction, ethyl acetate, ethanol extract of the antibacterial of nutmeg leaf and aloe vera leaf. The method uses was an experimental method with phytochemical screening, then manufacture of ethanol extracts of nutmeg leaves and aloe vera leaves, then fractionated with ethyl acetate solvent, then testes for antibacterial activity against Streptococcus mutans by the agar diffusion method. The results of the antibacterial activity test of the ethyl acetate fraction of nutmeg leaves showed the diamete of the inhibition zones at concentrations of 50%, 40%, 30%, 20%, and 10% were obtaines with inhibition zones of 16.2 mm, 15.46 mm, 15.2 mm, 12.26 mm and 11.76 mm. The test results on aloe vera leaf ethanol extract at concentrations of 50%, 40%, 30%, 20%, and 10 % were obtained with inhibition zones of 16.53 mm, 15.13 mm, 14.3 mm, 11,5 mm, and 11.3 mm. From the results of the study, it can be concluded that simplisia, ethanol extract, ethyl acetate fraction, n-hexane nutmeg leaf and aloe vera leaf contain secondary metabolites that act as antibacterial. The antibacterial activty of ethyl acetate fraction of nutmeg leaves was highest at a concentratioan of 50% with an inhibition zone of 16.2 mm and the antibacterial activity of aloe vera leaf ethanol extract was highest at a concentration of 50% with an inhibition zone of 16.53 mm in Streptococcus mutans which can be categorized as having strong inhibitory power.
Uji Aktivitas Antibakteri Sediaan Mouthwash Dari Ekstrak Daun Peppermint ( Mentha piperita L.) dan Daun Jarak Cina ( Jatropha multifida L.) Terhadap Streptococcus mutans Putri , Adilla; Nasution, Muhammad Amin; Lubis , Minda Sari; Nasution, Haris Munandar
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.917

Abstract

Background: Mouthwash is a liquid preparation that plays an important role in maintaining oral health. An ideal formulation should possess antibacterial effectiveness, physicochemical stability, and acceptable organoleptic properties. Streptococcus mutans is the primary pathogenic bacterium responsible for halitosis and dental caries. Peppermint (Mentha piperita L.) and physic nut (Jatropha multifida L.) leaves are known to contain bioactive compounds such as flavonoids, saponins, and tannins, which have potential antibacterial activity. Objective: This study aimed to formulate peppermint and physic nut leaf extracts into a stable mouthwash preparation and evaluate its antibacterial activity against Streptococcus mutans. Methods: The extracts were prepared using maceration with ethanol as a solvent. The mouthwash formulations were developed with three variations of extract concentrations (2%, 2.5%, and 3%). The preparations were then evaluated for their physical stability (organoleptic properties and pH) and tested for antibacterial activity against S. mutans using the Kirby-Bauer disc diffusion method. Inhibition zone data were statistically analyzed using ANOVA and Duncan’s test. Results: Physicochemical evaluation showed that all formulations remained stable over 28 days of observation, with a pH of 6, which is compatible with the oral cavity. Antibacterial testing demonstrated an increase in inhibition zone diameter with higher extract concentrations: 10.33 mm (2%), 11.1 mm (2.5%), and 11.9 mm (3%). These results were comparable to the positive control, Betadine gargle (11.95 mm). The negative control showed no inhibition zone. Statistical analysis revealed significant differences (p < 0.05) among the concentrations. Conclusion: The combination mouthwash containing peppermint and physic nut leaf extracts at a concentration of 3% was found to be the most stable formulation and exhibited the strongest antibacterial activity, comparable to the commercial reference product. Thus, this combination extract has potential to be developed as a natural antibacterial agent for oral health.
Edukasi dan Konseling Farmakoterapi untuk Masyarakat dalam Pengelolaan Penyakit Kronis Sari, Syilvi Rinda; Hindri Syahputri; Nia Novranda Pertiwi; Muhammad Amin Nasution; Muhammad Yunus
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 3 (2025): Juli-September 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i3.12874

Abstract

Penyakit kronis merupakan kondisi kesehatan jangka panjang yang memerlukan pengelolaan berkelanjutan agar kualitas hidup pasien dapat terjaga. Edukasi dan konseling farmakoterapi menjadi komponen penting dalam mendukung pasien memahami penggunaan obat secara tepat, meningkatkan kepatuhan pengobatan, serta mencegah komplikasi yang mungkin timbul. Edukasi dan konseling ini bertujuan untuk meningkatkan dan mengidentifikasi peran edukasi dan konseling farmakoterapi dalam membantu masyarakat dalam pengelolaan penyakit kronis di Apotek UMN Al Washliyah bertempat Jl. Gaharu II Kelurahan Harjosari I Kecamatan Medan Amplas, Kota Medan, Sumatera. Kegiatan penyuluhan dilakukan dengan metode ceramah langsung, konseling, diskusi, pemberian brosur dan tanya jawab. Penilaian terhadap keberhasilan kegiatan dilakuakan dengan menggunakan kuesioner. Hasil pengabdian menunjukkan bahwa intervensi edukasi dan konseling secara signifikan meningkatkan pengetahuan masyarakat mengenai penyakit kronis dan pengobatan, meningkatkan kepatuhan konsumsi obat. edukasi dan konseling farmakoterapi merupakan strategi efektif dalam mendukung pengelolaan penyakit kronis pada masyarakat, sehingga perlu diintegrasikan secara rutin dalam pelayanan kesehatan.
Antibacterial Activity and Thin-Layer Chromatography (KLT) Ethanol Extract of Dragon Scale Leaves (Drymoglossum piloselloides (L.) C. Presl) Against Bacteria Staphylococcus epidermidis Syahputri, Hindri; Pertiwi, Nia Novranda; Sari, Syilvi Rinda; Simanjuntak, Monica Nelly; Sari, Melia; Andry, Muhammad; Nasution, Muhammad Amin; Rezaldi, Firman
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7442

Abstract

The dragon scale plant is a plant containing flavonoid compounds, tannins, alkaloids, saponins. Flavanoid compounds, alkaloids, and tannins are found in dragon scales that are thought to provide antibacterial effects. Thin Layer Chromatography Test (KLT). On quarstin there is a stain distance spot of 1 cm and an 8 cm motion phase with an Rf value of 0.129 and in the extract there is a stain spot of 7.3 cm with an 8 cm motion phase with an Rf value of 0.9. In Staphylococcus epidermidis bacteria from the average of the largest inhibitory zones are applied to the extract with a concentration of 20%. The diameter of the average inhibitory zone formed around the disc paper at each concentration is: 5% 10.5 mm ± 0.20 at a concentration of 10% 11.26 mm ± 0.20 and a concentration of 20% 12.2 mm ± 0.30 each concentration has a strongly categorized response. Ethanol extract of dragon scale leaves (Drymoglossum piloselloides (L.) C. Presl) has antibacterial activity against Staphylococcus epidermidis. The diameter of the inhibitory zone that is best formed in the treatment of dragon scale leaf ethanol extract against Staphylococcus epidermidis bacteria with a concentration of 20%12.2 mm±0.30 is 12.2 mm with a strong category.
Co-Authors Abadi, Hafizhatul Ade Shindy F Br Sembiring Ade Sumiardi Adek Chan Anggi, Reza Destri Anny Sartika Daulay Anny Sartika Daulay Apmarja, Sarah Utami Arfiani Arifin Aris Ma'ruf Aryunda, Divia Asparyzha, Rhyzha Asyrun Alkhairi Lubis Awanis, Safirah Cut Nella Asyifa Didi Nurhadi Illian Dwiyarina Margarisa Fahma Shufyani Faisal, Hendri Fajar Fakri Fira Safitri Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Hari Hariadi Haris Munandar Nasution Hasibuan, Supia Indah Hendra Jaya Hendri Faisal Hendri Faisal Hendri Faisal Hindri Syahputri Ika Julianti Tambunan Ika Yeni Siahaan Indra Ginting Isti Dwi Pruschia Januri, Muhammad Rizal Jefri Naldi Khairani Fitri Khairani, Tetty Noverita Leni Halimatusyadiah Lestari, Seri Ligo, Azzura Lilik Septiana Lubis, Minda Sari Luthvia, Luthvia M. Fariz Fadillah M. Fariz Fadillah M. Pandapotan Nasution Mambang, D Elysa Putri Manik, Umi Chairani Mayang Sari Melia Sari Melia Sari Melia Sari, Melia Mirdha Iryana Muhammad Alifza Muhammad Andry Muhammad Yunus Muhammad Yunus Muhammad Yunus Mutia Muhardiyanti Nazirah, Nazirah Naziyah, Syifa Nia Novranda Pertiwi Nidia Rizka Niswa, Khairun Nurul Aulia Octania, Adelia Dwi Pradita, Diding Pricella Ginting Purba, Juvantri Fablo Putri , Adilla Rafita Yuniarti Rezaldi, Firman Rida Evalina Tarigan Ridwanto Ridwanto Rinda Sari, Sylvi Rudang, Singgar Ni Rumanti, Ruth Mayana Sahliah Sahliah, Sahliah Sari, Syilvi Rinda Selfia Lestary Shodikin, Marwan Ali Simanjuntak, Monica Nelly Siregar , Runisya Maugin Utami Siregar, Rina Paramitha Siska Dwi Anggraeni Suseno Amien Syafira, Nona Tanjung, M. Fadli Tetty Noverita Khairani Tia Nazilla Tri Damaiyanti Vannissa Andriani Irawan Winata, Hanafis Sastra Yadi, Hervi Yanti, Rahma Yayuk Putri Rahayu Yulia Nanda Putri Yuniarti , Rafita Yuniarti, Rafita Yusep Ikrawan Zahara, Fitria Siti Zhafirah, Rana Zikra Maqfirah Ziza Putri Aisyia Fauzi Zulmai Rani