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All Journal Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Jurnal Riset Kimia Journal of Agromedicine and Medical Sciences BIOMA : Jurnal Biologi Makassar Jurnal Penelitian Kesehatan Suara Forikes Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Ilmiah Universitas Batanghari Jambi JURNAL KESEHATAN PERINTIS Majalah Kedokteran Andalas Jurnal Biomedika dan Kesehatan Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Nusantara Hasana Journal Jurnal EduHealth Jurnal Ilmu Kesehatan Indonesia (JIKSI) Andalas Dental Journal Sciences of Pharmacy Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Jurnal Sains Farmasi dan Kesehatan Jurnal Sains, Teknologi dan Kesehatan
Almurdi Almurdi
Andalas University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Risiko Mual Muntah Pasca Operasi pada Pasien Seksio Sesarea dengan Anestesi Spinal di RSIA Permata Bunda Solok Mashoed, Meyfiana Aisyah; Rustini , Rini; Vitresia , Havriza; Syahrul , Muhammad Zulfadli; Almurdi, Almurdi
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 3 (2025): September 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i3.1305

Abstract

Latar Belakang: Mual dan muntah pasca operasi (PONV) merupakan salah satu efek samping pada anestesi spinal pada pasien seksio sesarea. Faktor risiko dari kejadian mual muntah pasca operasi adalah usia, IMT, motion sickness, mual muntah pasca operasi sebelumnya, dan merokok. Tujuan: Mengetahui angka kejadian dan faktor risiko mual muntah pasca operasi pada pasien seksio sesarea di RSIA Permata Bunda Solok. Metode: Penelitian ini adalah deskriptif observasional yang dilakukan pada bulan November 2023 di Recovery Room RSIA Permata Bunda Solok. Sampel sebanyak 46 pasien yang menjalani operasi seksio sesarea dengan anestesi spinal diambil menggunakan teknik accidental sampling. Hasil: Didapatkan sebanyak 7 dari 46 pasien (15,22%) mengalami mual muntah pasca operasi. Berdasarkan usia, kejadian mual muntah pasca operasi terbanyak pada kelompok usia 26-35 tahun (10,87%). Berdasarkan kelompok IMT, kejadian mual muntah terbanyak pada IMT >27 (20%). Motion sickness dengan yang tidak ada Motion sickness tidak jauh berbeda angka kejadian mual muntah pasca operasi (22,22% dan 10,71%). Dari 7 pasien yang mengalami mual muntah pasca operasi semuanya memiliki riwayat tidak merokok dan riwayat tidak PONV sebelumnya (100%). Kesimpulan: Angka kejadian mual muntah pasca operasi yang tidak jauh berbeda dengan studi yang pernah dilakukan sebelumnya dan hal ini dipengaruhi oleh faktor risiko usia, IMT, Motion sickness, PONV sebelumnya dan riwayat merokok.
Exploring the Effects of Bone Marrow Mesenchymal Stem Cells on Amyloid Plaque Reduction in a Rat Model of Alzheimer's Disease Annita, Annita; Revilla, Gusti; Ali, Hirowati; Almurdi, Almurdi
Majalah Kedokteran Andalas Vol. 47 No. 1 (2024): MKA Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i6.p1036-1044.2023

Abstract

Objective: This study aimed to evaluate the therapeutic potential of Bone Marrow-derived Mesenchymal Stem Cells (BM-MSCs) in mitigating amyloid plaque formation in Alzheimer's disease induced by Aluminum Chloride (AlCl3) in rats. Methods: Rats were divided into three groups: negative control, positive control (AlCl3-induced), and treatment (AlCl3 + BM-MSCs). Cognitive function was assessed five days post-induction, and amyloid plaques were quantified using Congo Red staining in the cortex and hippocampus. Results: A significant reduction in amyloid plaque was observed in rats treated with BM-MSCs. The proportion of stained areas decreased from 1.88 to 1.73 in the cortex and from 1.61 to 1.47 in the hippocampus, compared to AlCl3-only controls. Conclusion: BM-MSCs demonstrated a moderate but statistically significant reduction in amyloid plaque in a rat model of Alzheimer's disease, indicating their therapeutic potential.
Co-Authors Adrial Adrial Afriani, Nita Alan Mustaqim Amelin, Fitrisia Annita Annita Annita, Annita Ansori, Fachrurrazi Al Ariani Zaltin Okvenda Arizal, Chairani Asterina Asterina Aswiyanti Asri Aswiyanti Asri Azzati, Normaida Baizura Bobby Indra Utama Citra Manela Cut Mutiara Sabrina Dessy Arisanti Dessy Arisanti Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Dian Puspita Djong Hon Tjong Dwi Yulia Dwitya Elvira, Dwitya Efrida Efrida Efrida Efrida Efrida, Efrida Eka Nofita Elly Usman Ellyza Nasrul Elmatris Sy Elmatris, Elmatris Endrinaldi Endrinaldi Endrinaldi Erly Erly Eti Yerizel Febriyanti, Rizka Fenty Primadhani Frizki Amalya Putri Gita Rahmadani Gusti Revilla Gusti Revilla Hasmiwati Hasnidahlena Hendra Permana Hendriati, Hendriati Herman, Deddy Hirowati Ali Hirowati Ali, Hirowati Husnil Kadri Ida Rahmah Burhan Inayah Afrilina Isnindiah Koerniati Istiya Putri Lestari Julizar Julizar Julizar Nazar Khairunnisa, Ainindia Kosno Suprianto Lili Irawati Linosefa Linosefa Lydia Susanti, Lydia M Ikhsan Mahata, Liganda Endo Malinda Meinapuri Mashoed, Meyfiana Aisyah Mega Ade Nugrahmi Meri Wulandari Millah Fithriyah Zindany Mohamad Reza Mohamad Reza Muhammad Iqballisandi Nabila, Fathiya Sarah Netti Suharti Nova Mustika Noverial, Noverial Nur Afrainin Syah Nur Indrawati Lipoeto Nur Indrawati Lipoeto Nuzulia Irawati Rahmadina, Rahmadina Rahmadina, Rahmadina Rahman, Rifna Alya Rahmayana Rahmayana Rahmi Lestari Raissa Febrina Ramadhani, Melati Nurul Rauza Sukma Rita Raveinal Yerizel Restu Susanti Rifka Rahmat Rikarni Rikarni Rinal Effendi Rita Permatasari Russilawati, Russilawati Rustini , Rini Ryri Rahmawati Helmi Salsabilah Firdausiah Saptino Miro Saptino Miro, Saptino Silfina Indriani Sitti Monica Astrilia Ambon Sofitri Sofitri Sri Indrayati Sukri Rahman Syahrul , Muhammad Zulfadli Syandrez Prima Putra Ulya Uti Fasrini Utami, Putra Rahmadea Vitresia , Havriza Wendy Syafutra Yaslinda Yaunin Yeyep Natrio Yulia, Dwi Yuliarni Syafrita Yusri, Elfira YUSTI SIANA Yustini Alioes Zelly Dia Rofinda