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An in Vitro Approach: Antibacterial Activity of Sansevieria trifasciata Prain. Leaves with Chemometric Analysis Kasmawati, Henny; Sida, Nurramadhani A.; Arfan, Arfan; Indrayanti, Wa Ode Dian; Rusman, Arman
Jurnal Sains dan Kesehatan Vol. 6 No. 1 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i1.2087

Abstract

Exploration the antibacterial activity of S.trifasciata Prain. is still limited, therefore this study aims to assess the antibacterial activity of extracts and ethyl acetate fractions of Sansevieria trifasciata Prain. The S.trifasciata leaves was macerated with ethanol 96%, then fractionated using the trituration method with ethyl acetate. The treatment group was divided into positive control group (PC) using ciprofloxacin, negative control (NC) using DMSO, extract, ethyl acetate fraction 5% (ET5%), 10% (ET10%), 20% (ET20%), 40% (ET40 %). Data were analyzed statistically by ANOVA and chemometrically with PCA. The inhibition zone for S.aureus bacteria in each sample is 26.69; 1.40; 23.32;2.82; 6.23; 11.11; 20.15 mm, respectively, E.coli is 26.65;0.63;22.65;3.61;7.11;11.44;21.15 mm respectively, P. aeruginosa is 27.40; 0.00; 23.23; 2.74;7.03;11.69;21.36 mm respectively. Percent inhibition of extract, ET5%, ET10%, ET20%, ET40% on S. aureus bacteria is 82.16; 5.31; 18.12; 36.39; 70.38% respectively, E.coli is 82.67; 11.13; 24.31; 40.56; 76.99% respectively, P. aeruginosa 84.85; 10.01; 25.65; 42.68; 77.98% respectively. Extract and ethyl acetate fraction have significant potential as antibacterial (p<0.05). The results of PCA chemometric analysis showed that the extract and ET40% had similar inhibition zone area to the positive control ciprofloxacin. The extract and the ethyl acetate fraction 40% are promising for development as antibacterials. Keywords:          Sansevieria trifasciata Prain., chemometric, bacterial
Edukasi Kesehatan tentang Tuberkulosis: Membangun Komitmen Masyarakat untuk Pengendalian TBC Kasmawati, Henny; Hikmah, Nurull; Trinovitasari, Nita; Jannah, Sitti Raodah Nurul; Malina, Rachma; Suryani, Suryani; Nuralifah, Nuralifah; Aswani, Aswani
JIPITI: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 4 (2025): November 2025 - JIPITI: Jurnal Pengabdian kepada Masyarakat
Publisher : PT. Technology Laboratories Indonesia (TechnoLabs)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tuberculosis (TB) is an infectious disease that is still a global health problem, caused by the bacterium Mycobacterium tuberculosis, which is acid-resistant and mainly attacks the lungs, but can also attack other organs. This disease can affect people of all ages, including babies, children, adults, and the elderly. TB transmission occurs through the air from people who cough or sneeze, with the main factors affecting public health being environmental factors and behaviours, such as uncovered coughing and poor sanitation. TB cases in Southeast Sulawesi Province have shown a significant upward trend in recent years, with the incidence rate continuing to rise every year. The success of TB treatment is influenced by a variety of factors, including medication adherence, which is a major challenge to avoid the emergence of drug resistance, such as TB-MDR. The Government of Indonesia has issued policies and focuses on reducing TB incidence through education and socialisation to encourage active community involvement in TB control to achieve the national target by 2030.
PERAN MAHASISWA APOTEKER UHO DAN BNN DALAM CEGAH PENYALAHGUNAAN NARKOBA SINTESIS SERTA EDUKASI BAHAYA ROKOK ELEKTRIK YANG MENGANCAM GENERASI MUDA GUNA MEWUJUDKAN GENERASI SEHAT TANPA NARKOBA Kasmawati, Henny; Indalifiany, Astrid; Sida, Nurramadhani A.; Puriandani, Ketut Ayu; Pratiwi, Dinda; Fauziah, Nining; Azis, Nurul Ella Kholifatul; Widari, Niluh Putri Sri; Putri, Egi Alisa; Mulya, Elzah; Trihafsari, Hanin
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 12 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Desember 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i12.2146

Abstract

The abuse of synthetic drugs and the increasing use of electronic cigarettes among adolescents pose a serious threat to public health and the future of young generations. Limited awareness of the dangers of synthetic drugs and the misconception that electronic cigarettes are safer than conventional cigarettes contribute to adolescents’ vulnerability. This community service program aimed to enhance students’ knowledge and awareness of the risks associated with synthetic drugs and electronic cigarette use through collaboration between Pharmacy Students of Universitas Halu Oleo and the National Narcotics Agency. The program employed educational counseling, interactive lectures, and question-and-answer sessions tailored to adolescent characteristics. The materials covered types and health impacts of synthetic drugs, risks of electronic cigarette use, and students’ roles in preventing drug abuse in school environments. The results showed improved knowledge, increased awareness, and stronger commitment among students to avoid synthetic drugs and electronic cigarettes. Active participation during discussions demonstrated the effectiveness of collaboration between educational institutions and government agencies in strengthening drug abuse prevention and promoting healthy lifestyle behaviors.
EDUKASI DAN PELAYANAN KESEHATAN MASYARAKAT DALAM KEGIATAN ROAD TO HARI KESEHATAN NASIONAL (HKN) KOTA KENDARI TAHUN 2025 Parawansah, Parawansah; Kasmawati, Henny; Yamin, Yamin; Fataraing, Tridamayanti; Rahman, Hutamy Viranda; Adha, Muh Aidil; Awandhaputri, Ghina Salsabila; Dahlan, Rahimah Nurfadilah; Tama, Dias; Ardani, Sherly Intan; Akbar, Wandarsih Juniarti
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Januari 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i1.2165

Abstract

Road to Hari Kesehatan Nasional (HKN) Kota Kendari Tahun 2025 merupakan kegiatan promotif dan preventif yang bertujuan meningkatkan derajat kesehatan masyarakat melalui pelayanan kesehatan dan edukasi langsung. Kegiatan ini melibatkan Dinas Kesehatan Kota Kendari dan mahasiswa Program Studi Pendidikan Profesi Apoteker Universitas Halu Oleo sebagai bentuk implementasi Tri Dharma Perguruan Tinggi. Tujuan kegiatan pengabdian masyarakat ini adalah menjalin kemitraan antara Tim Pengabdian Masyarakat Mahasiswa Profesi Apoteker UHO dan Dinas Kesehatan Kota Kendari, berpartisipasi aktif dalam rangkaian Road to HKN Kota Kendari 2025 melalui pelaksanaan Cek Kesehatan Gratis, mendukung kelancaran kegiatan dengan bantuan tenaga dan dokumentasi, serta meningkatkan kesadaran mahasiswa akan pentingnya peran tenaga kesehatan dalam kegiatan sosial dan edukatif. Metode pelaksanaan meliputi edukasi kesehatan secara langsung, pendampingan pelayanan cek kesehatan gratis, serta dokumentasi kegiatan. Sasaran kegiatan adalah masyarakat umum yang hadir di lokasi kegiatan Road to HKN. Hasil kegiatan menunjukkan antusiasme masyarakat yang tinggi terhadap pelayanan kesehatan dan edukasi kefarmasian. Masyarakat memperoleh pemahaman terkait kesehatan mata, tuberkulosis, Beyond Use Date (BUD), prinsip DAGUSIBU serta Pencegahan Penyakit Tidak Menular (PTM). Kegiatan ini memberikan kontribusi positif dalam meningkatkan literasi kesehatan masyarakat. Kesimpulan dari kegiatan ini adalah bahwa keterlibatan mahasiswa profesi apoteker dalam pengabdian masyarakat mampu mendukung peningkatan derajat kesehatan masyarakat secara nyata.
Effect of Solvent Polarity on Antioxidant and Antidiabetic Activity of Kesambi Leaf Extract (Schleichera oleosa L.) Nursamsiar, Nursamsiar; Marwati, Marwati; Sami, Fitriyanti J.; Nur, Syamsu; Kasmawati, Henny; Asnawi, Aiyi
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.9439

Abstract

Kesambi (Schleichera Oleosa (L.) is one of the beneficial plants in Indonesia which contains fenolic and flavonoids that exhibit antioxidant properties. The presence of antioxidants in plants could be associated with antidiabetic activity of these plants. This research was conducted to determine the antioxidant and antidiabetic activities of n-hexane, ethyl acetate, acetone and methanol extracts from Kesambi leaves. Extraction was carried out by the ultrasonic assisted extraction (UAE) method. The antioxidant activity was determined quantitatively by DPPH and ABTS method, while the antidiabetic activity was evaluated by using α-glukosidase inhibition method. The IC50 values from the determination of antioxidant and antidiabetic activities were obtained by using Microplate reader at the maximum wavelength. Results of the antioxidant determination DPPH method showed that IC50 values of n-hexane, ethyl acetate, acetone and methanol extracts were 414.1993; 57.7862; 6.33 dan 13.4558 µg/mL, respectively. And for ABTS method showed 162.679; 22.6684; 10.7975; dan 146.869 µg/mL. This indicates the acetone and methanol extracts give the best results in antioxidant activity. Meanwhile, IC50 values of in vitro antidiabetic activity of n-hexane, ethyl acetate, acetone and methanol extracts were 99.3235; 272.8723; 1.6799; dan 24.4653 µg/mL, respectively. Acetone and methanol extracts of kesambi leaf give the best results in antidiabetic activity.
Co-Authors ,, Suryani A Sida, Nurramadhani A.A. Ketut Agung Cahyawan W Abd Rafid Achmad Fuad Hafid Adha, Muh Aidil Aiyi Asnawi Akbar, Wandarsih Juniarti Alfad Fadri Alfian Alfian Anjani, Ratna Anwar, Irvan Ardani, Sherly Intan Arfan Arfan Arfan Arfan Ariani, Eno Retno Armadani, Fery Indradewi Aspadiah, Vica Aswani Aswani Aswani Aswani Aswani Aswani Aswani Aswani Aswani, Aswani Aty Widyawaruyanti Awandhaputri, Ghina Salsabila Azis, Nurul Ella Kholifatul Dahlan, Rahimah Nurfadilah Damu, Rusliati Desi Sartina Dian Munasari Solo Eka Pebriana Eka, Bau Mirna Ayu Fataraing, Tridamayanti Fauziah, Nining Fery Indradewi Fery Indradewi Armadany Fifi Nirmala Firawati Fitrawan, La Ode Muhammad Fitri Rahmadani Saputri Fitriyanti Jumaetri Sami Fristiohady, Adryan Halik Hasnawati Hasnawati Hasniar, Wa Ode Hikmah, Nurull Indalifiany, Astrid Indrayanti, Wa Ode Dian Jamil, Siti Amaliah Jamsir, Asmaidah Jannah, Sitti Raodah Nurul La Ode Aman La Ode Muh. Fitrawan La Ode Muhammad Diman La Ode Muhammad Fitrawan Linggi Allo, Lisa Talita Loly Subhiaty Idrus Loly Subhiyati Idrus Madjid, Waode Istiqamah Malaka, Muhammad Hajrul Malina, Rachma Mallarangeng, Andi Nafisah Tendri Adjeng Mardiani, Siti Marwati Marwati Marwati Marwati Mesi Leorita, Mesi Muh. Arba Mulya, Elzah Munarsi Munarsi Mutmainna, Mutmainna Nina Salamah Ningsih, Warda Ayu Nur Filzanah Nur Illiyyin Akib Nur Illiyyin Akib Nur Illiyyin Akib Nur Kharisma Amin Nur Rayani Nur Syam Hidayah Rahma Ismail Nuralifah Nuralifah, Nuralifah NURFAUSIAH Nurramadhani A. Sida Nursamsiar Nursamsiar Nurull Hikmah Nurull Hikmah Parawansah Parawansah, Parawansah Pratiwi, Dinda Puriandani, Ketut Ayu Putri, Egi Alisa Rahman, Hutamy Viranda RAHMAT MULIADI, RAHMAT Rahmayani, Nur Rayani, Nur Ridho Fajriyah Jamri Rifa’atul Mahmudah Rimala Sanipurnama Kindkasman Rini Hamsidi Ruben, Sony Ruslin Ruslin Ruslin , Ruslin Ruslin Ruslin Ruslin Ruslin Ruslin Ruslin Ruslin Ruslin, R Ruslin, Ruslin Rusman, Arman Sabarudin Sabarudin Sabarudin Sabarudin Sabarudin Sabarudin Sabarudin, S Sami, Fitriyanti J. Sarmita, Sarmita Septiyana, Wanda Sida, Nurramadhani A. Sida, Nurramdhani A. Siti Ruhima Sitti Raodah Nurul Jannah Soleman, Imelda Sarda Sudiman, Aswan Sunandar Ihsan Sunandar Ihsan Sunandar Ihsan Sunandar Ihsan Sunandar Ihsan, Sunandar Sundar Ihsan Sundar Ihsan Suprianti, Rani Suriani Suriani Suryani Suryani Suryani, S Syamsiar, Syamsiar Syamsu Nur, Syamsu Tama, Dias Tri Handayani Trihafsari, Hanin Trinovitasari, Nita Vica Aspadiah W Wahyuni, W Wa Ode Dian Indrayanti Wanda Hamidah Wardana, Gede Yogi Prana Widari, Niluh Putri Sri Wiwied Ekasari Yamin Yamin , Yamin Yamin Yamin, Y Yamin, Yamin Zubaydah, Wa Ode Sitti