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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Well Being PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara J-CEKI Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Abdimas Paspama Jurnal Bioteknologi & Biosains Indonesia
Yuneka Saristiana
Prodi Pendidikan Profesi Apoteker, Fakultas Ilmu Kesehatan, Universitas Kadiri
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Prediction of Augenol in Cinnamon (Cinnamomum burmannii) Boiled as a Carminative to Overcome Floating Stomach Rika Wahyu Pujiastini; Fendy Prasetyawan; Yuneka Saristiana; M. Wahyu Ariawan; Muhammad Nurul Fadel; Emma Jayanti Besan
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 1 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i1.2

Abstract

Flatulence (meteorismus) is a common condition caused by excess gas accumulation in the digestive tract. One alternative traditional treatment to overcome this condition is the use of herbal plants, such as cinnamon (Cinnamomum burmannii). This study aims to predict the potential of eugenol, an active compound in cinnamon, as a carminative agent using an in silico approach. Data were obtained from PubChem and analyzed using PASS Online to predict its pharmacological activity. The results of the analysis showed that eugenol has a probability of activity as a carminative of 0.941 and a probability of inactivity of 0.001, indicating high potential in helping to relieve flatulence. Thus, eugenol in cinnamon has the potential as an alternative natural treatment to overcome digestive disorders, especially bloating.
Pharmacokinetic Prediction Of Apigenin From Celer (Apium Graveolens L.) Using Pkcsm Lusiana Aprillia; Fendy Prasetyawan; Yuneka Saristiana; Ratna Mildawati; Chandra Arifin; Abd Rofiq
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 1 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i1.3

Abstract

Celery (Apium graveolensL.) is a plant that has various pharmacological activities. One of the main bioactive compounds in celery is apigenin. Understanding the pharmacokinetic properties of apigenin is very important in evaluating its effectiveness and safety as a drug candidate. This study aims to predict the pharmacokinetic properties of apigenin using the pkCSM computational approach. The prediction results show that apigenin has good intestinal absorption, but low water solubility. Distribution ability is moderate, with limited penetration into the central nervous system. Apigenin is not a major substrate of CYP2D6 and CYP3A4 enzymes, but can inhibit CYP1A2 and CYP3A4. The elimination rate is moderate. Apigenin is not mutagenic, not hepatotoxic, and does not cause cardiotoxic effects. Apigenin has low toxicity toT. pyriformisand safe in acute doses with an LD50 of 2,432 log mM.
Kombucha Tea as a Health Alternative in the Context of Quantum Entanglement in the Era of the COVID-19 Pandemic in the Pharmaceutical Context Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Asrizal Azis; Ema Tri Wulan; Ratna Mildawati
Abdimas Paspama Vol. 2 No. 02 (2024): Abdimas Paspama, June 2024
Publisher : Abdimas Paspama

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Abstract

In the midst of the COVID-19 pandemic, exploring innovative health alternatives becomes imperative. This study delves into the role of Kombucha Tea as a promising health option within the framework of quantum entanglement. Kombucha, a fermented beverage with roots in various cultures, offers a plethora of health benefits. Through community engagement efforts conducted in 2021, we aimed to raise awareness about Kombucha Tea and its significance in fostering holistic health amidst the pandemic. The socialization activities encompassed informative sessions, practical workshops, and training programs to disseminate knowledge and empower individuals regarding Kombucha Tea. These initiatives aimed to highlight the intricate relationship between individuals, their environment, and overall well-being, underpinned by the concept of quantum entanglement. The sessions provided insights into the fermentation process of Kombucha Tea, its health benefits, and practical tips for its integration into daily lifestyles. Results indicated a high level of interest among participants in Kombucha Tea as an alternative health option. The sessions fostered a deeper understanding of its health benefits, particularly in enhancing immune function and digestive health. Moreover, participants expressed enthusiasm for incorporating Kombucha Tea into their daily routines. The program's success was further evidenced by the positive feedback received from both participants and community leaders. The interactive nature of the workshops and the informative materials distributed contributed to enhancing public awareness and understanding of Kombucha Tea's potential contributions to health.
Socialization of the Level of Public Awareness and Knowledge about the Benefits of Kombucha Tea in Overcoming Sleep Paralysis During the COVID-19 Pandemic Yuneka Saristiana; Fendy Prasetyawan; Chadra Arifin; Widhi Astutik; Wahyu Ariawan; Achmad Wahdi
Abdimas Paspama Vol. 2 No. 1 (2023): Abdimas Paspama, December 2023
Publisher : Abdimas Paspama

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Abstract

The COVID-19 pandemic has profoundly impacted global public health, prompting a heightened focus on both physical and mental well-being worldwide. In this uncertain landscape, sleep paralysis has emerged as a notable health concern, characterized by the inability to move or speak upon waking or falling asleep, often accompanied by distressing hallucinations. With stress levels on the rise during the pandemic, cases of sleep paralysis have shown an upward trend. Conversely, probiotic beverages like kombucha tea have garnered attention for their potential health benefits, including digestive improvement, enhanced energy levels, and better sleep quality. Despite these benefits, public awareness regarding kombucha tea's efficacy in addressing sleep paralysis remains limited.To address this knowledge gap, a community service program has been developed to educate the public about kombucha tea's potential in managing sleep paralysis amidst the COVID-19 pandemic. The program involves collaboration with local communities, health institutions, and experts in mental health and nutrition. Scheduled for January 2021, the program will be executed across various locations, engaging community members and fostering dialogue on sleep health and nutrition. Preliminary results indicate a significant improvement in public understanding of sleep paralysis and kombucha tea benefits post-program. Participants exhibited heightened awareness of symptoms, causes, and treatment options for sleep paralysis, as well as a better grasp of kombucha tea's health advantages. Practical workshops on kombucha tea preparation garnered considerable interest, signaling a potential shift towards healthier lifestyle choices among participants.
PREVENTION OF GASTROPROTECTIVE ACTIVITY OF CHINESE BETEL EXTRACT (PEPEROMIA PELLUCIDA L.) ON THE HISTOPATHOLOGICAL FEATURES OF THE STOMACH IN A MOUSE MODEL OF GASTROENTERITIS Savitri, Lisa; Prasetyawan, Fendy; Saristiana, Yuneka; Juwita, Syntia Tanu; Amanda, Cornelia; Mebung, Konradus Klala
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.8156

Abstract

Gastroenteritis is a common gastrointestinal disorder characterized by inflammation of the stomach and small intestine, often leading to symptoms such as diarrhea, vomit-ing, and abdominal pain. This study investigates the gastroprotective effects of Pepe-romia pellucida (Chinese betel) extract on histopathological features of the stomach in a mouse model of gastroenteritis. Male Swiss strain mice, aged 2-3 months, were treated with different doses of P. pellucida extract (100, 300, and 500 mg/kg BW) for 7 days after inducing gastroenteritis with Escherichia coli infection. Histopathological ex-amination showed that the extract significantly reduced cell degeneration, necrosis, and polymorphonuclear leukocyte infiltration in the stomach compared to the negative control group. The highest dose (500 mg/kg BW) exhibited the most prominent gastro-protective effect. These results suggest that P. pellucida possesses promising thera-peutic potential for gastroenteritis, possibly due to its bioactive compounds such as flavonoids, tannins, and saponins. Further studies are needed to explore the underly-ing mechanisms and optimize its therapeutic application.
ANALISIS KANDUNGAN FORMALIN DAN BORAKS PADA BUMBU GILING YANG DIJUAL DI PASAR AJIBARANG WETAN mildawati, ratna; Khumaini, Eko Hidayaturrohman; Prasetyawan, Fendy; Saristiana, Yuneka
PHARMACON Vol. 14 No. 3 (2025): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.14.2025.61687

Abstract

Ground spices are a key ingredient used as food additives in almost every dish, whether at home or in places that sell various types of food. The use of food additives (BTP) in food production processes needs to be closely monitored. Additives that are prohibited include formalin and borax. Formalin and borax are banned because they can cause damage to the brain, liver, and kidneys, and long-term use can result in death. This study aims to determine whether formalin and borax are present in ground spices sold at Ajibarang Wetan Market. The ground spice samples examined came from two vendors: Vendor A (garlic, galangal, ginger, candlenut, red chili, turmeric, mixed spices, and coriander) and Vendor B (shallots, garlic, turmeric, red chili, candlenut, and mixed spices). The ground spice samples sold by Vendor A and Vendor B tested negative for both formalin and borax. The method used involved color reaction tests. To detect formalin, a potassium permanganate (KMnO₄) color reaction was used, and to detect borax, turmeric paper was employed. The conclusion of this study is that the borax test results for both vendors (Vendor A and Vendor B) were negative, as there was no color change to orange or reddish-brown. The formalin test results for both vendors were also negative, as there was no change in color to clear.
Analisis Histopatologi Efek Antiinflamasi Ekstrak Etanol Daun Akar Sebiak (Gynura procumbens (Lour.) Merr.): Histopathological Analysis of the Anti-inflammatory Effect of Ethanol Extract of Akar Sebiak Leaves (Gynura procumbens (Lour.) Merr. Saristiana, Yuneka; Prasetyawan, Fendy; Savitri, Lisa
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 7 No. 1 (2025): Volume 7 No 1 2025
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v7i1.6670

Abstract

Penelitian ini bertujuan mengevaluasi efek antiinflamasi ekstrak etanol daun Akar Sebiak (Gynura procumbens (Lour.) Merr.) melalui analisis histopatologi pada tikus putih jantan yang diinduksi Complete Freund’s Adjuvant (CFA). Hewan uji dibagi menjadi lima kelompok: kontrol normal, kontrol positif (Triamsinolon Asetonid), kontrol negatif (CMC-Na 1%), dan ekstrak dosis 100 mg/kg BB serta 200 mg/kg BB. Parameter yang diamati meliputi penurunan volume udem, jumlah leukosit total, dan lebar joint space. Hasil menunjukkan ekstrak dosis 100 mg/kg BB dan 200 mg/kg BB menurunkan volume udem masing-masing sebesar 43,33% dan 49,15%, menurunkan jumlah leukosit, serta memperbaiki joint space dibandingkan kontrol negatif. Efek antiinflamasi ini diduga terkait kandungan flavonoid, alkaloid, dan triterpenoid/steroid yang menghambat jalur inflamasi. Meskipun potensi ekstrak signifikan, efeknya masih di bawah triamsinolon asetoniid.
Pengenalan Metode Imunodiagnostik Dasar untuk Pencegahan Penyakit Menular di Peternakan Savitri, Lisa; Kasimo, Elfred Rinaldo; Krissanjaya, Rochmad; Prasetyawan, Fendy; Saristiana, Yuneka; Amanda, Cornelia; Mebung, Konradus Klala
Abdimas Galuh Vol 8, No 1 (2026): Maret 2026
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v8i1.23354

Abstract

Penyakit menular pada ternak masih menjadi salah satu kendala utama dalam usaha peternakan rakyat karena dapat menurunkan produktivitas dan menyebabkan kerugian ekonomi. Salah satu upaya pencegahan yang dapat dilakukan adalah deteksi dini penyakit melalui metode imunodiagnostik dasar. Namun, tingkat pemahaman peternak mengenai prinsip kerja dan pemanfaatan metode imunodiagnostik masih relatif rendah. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan pemahaman peternak mengenai pengenalan penyakit menular serta prinsip dasar metode imunodiagnostik sebagai langkah awal pencegahan penyakit di peternakan. Kegiatan dilaksanakan melalui penyuluhan interaktif, diskusi dua arah, serta demonstrasi penggunaan alat imunodiagnostik dasar berupa kit uji cepat. Sasaran kegiatan adalah peternak ternak rakyat di wilayah sasaran pengabdian. Evaluasi dilakukan melalui pengukuran tingkat pengetahuan peserta sebelum dan sesudah kegiatan serta observasi partisipasi aktif selama kegiatan berlangsung. Hasil kegiatan menunjukkan adanya peningkatan pemahaman peternak terkait jenis penyakit menular, prinsip reaksi antigen–antibodi, dan manfaat penggunaan metode imunodiagnostik dalam deteksi dini penyakit. Selain itu, peternak menunjukkan antusiasme dan partisipasi aktif selama proses penyuluhan dan demonstrasi. Kegiatan ini memberikan kontribusi positif dalam meningkatkan kesadaran peternak terhadap pentingnya pencegahan penyakit menular melalui pendekatan diagnostik sederhana yang aplikatif di tingkat peternakan rakyat.
Co-Authors Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Akhmal, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arsiaty Sumule Ary Kristijono Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Charliandri Saputra Wahab Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Emma Jayanti Besan Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hakim, Adiyansyah Lukman Hasriyani Hasriyani Hasriyani, Hasriyani Herman Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Khumaini, Eko Hidayaturrohman Kristjono, Ary Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Okky Intan Mawarni Oktadiana, Isma Prasetyo Nugroho, Bandhi Prayoga Fery Yuniarto Probosiwi , Neni Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Shinta Mayasari Shinta Mayasari Sugeng Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Zahra, Ilhawa