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All Journal Biology, Medicine, & Natural Product Chemistry Journal of Islamic Pharmacy Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat HERBAPHARMA : Journal of Herb Farmacological Borneo Journal Of Pharmascientech Jurnal Abdimas Ilmiah Citra Bakti (JAICB) Jurnal Mandala Pengabdian Masyarakat Well Being Jurnal EduHealth PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Ilmiah STIKES Yarsi Mataram Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) International Journal of Global Sustainable Research Indonesian Journal of Community Empowerment Jurnal Intelek Dan Cendikiawan Nusantara Jurnal Penelitian Sains dan Kesehatan Avicenna IJF (Indonesia Jurnal Farmasi) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara Jurnal Ilmu Kesehatan J-CEKI Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Journal Abdimas Paspama Service Jurnal Bioteknologi & Biosains Indonesia
Fendy Prasetyawan
Prodi Pendidikan Profesi Apoteker, Fakultas Ilmu Kesehatan, Universitas Kadiri
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Prediction of Scabertopin from Tapak Liman (Elephantopus scaber) for Antileukemic Saristiana, Yuneka; Prasetyawan, Fendy; Salmasfattah, Novynanda; Ilmi, Tsamrotul; Fadel, Muhammad Nurul; Besan, Emma Jayanti
Multicore International Journal of Multidisciplinary (MIJM) Vol. 1 No. 1 (2025): May
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mijm.v1.i1.5

Abstract

Leukemia remains a significant global health challenge, necessitating the exploration of novel therapeutic agents with improved efficacy and safety profiles. Elephantopus scaber (commonly known as Tapak Liman) is a medicinal plant traditionally used for various ailments, including cancer. Scabertopin, a sesquiterpene lactone isolated from E. scaber, has attracted scientific interest due to its potential antileukemic properties. This study aims to predict the antileukemic activity of Scabertopin through an in silico approach. The compound's chemical structure was retrieved in SMILES format from the PubChem database and analyzed using the PASS (Prediction of Activity Spectra for Substances) online tool. The prediction results indicated a high probability of antileukemic activity, with a Pa (probability of activity) value of 0.822 and a Pi (probability of inactivity) value of 0.004. These findings suggest a strong likelihood that Scabertopin exhibits antileukemic effects, supporting its potential as a candidate for further pharmacological and clinical investigations. The use of computational prediction tools provides an efficient and cost-effective preliminary screening method for identifying promising bioactive compounds from natural sources. This study contributes valuable insights into the therapeutic potential of Scabertopin and highlights the importance of traditional medicinal plants in drug discovery for leukemia treatment.
Pharmacokinetics and Druglikeness of Amoxicillin Drug using SwissADME Prasetyawan, Fendy; Saristiana, Yuneka; Mildawati, Ratna; Rhomah, Eka Hayati; Fadel, Muhammad Nurul; Besan, Emma Jayanti
Multicore International Journal of Multidisciplinary (MIJM) Vol. 1 No. 2 (2025): November
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mijm.v1.i2.3

Abstract

Amoxicillin, a widely utilized semi-synthetic penicillin derivative, remains a cornerstone in treating various bacterial infections. Despite its extensive clinical application, a comprehensive in silico assessment of its pharmacokinetic and "druglikeness" properties using modern computational tools can provide valuable complementary insights. This study employed the SwissADME web platform to meticulously analyze the computed descriptors, physicochemical characteristics, ADME profile, druglikeness, and medicinal chemistry aspects of amoxicillin. The chemical structure of amoxicillin, represented by its SMILES string, was retrieved from the PubChem database and subsequently input into SwissADME for analysis. The results indicate that amoxicillin possesses a molecular weight of 365.40 g/mol and a hydrophilic nature, as evidenced by its consensus LogP value of -0.39 and high water solubility predictions. Its Topological Polar Surface Area (TPSA) is 158.26 Ų, and it contains 4 hydrogen bond donors and 6 hydrogen bond acceptors. While the in silico prediction for gastrointestinal (GI) absorption was "Low" (likely due to the high TPSA and hydrophilicity, suggesting reliance on active transport mechanisms in vivo), amoxicillin fully complies with Lipinski's Rule of Five, indicating good oral bioavailability potential. Furthermore, it is predicted not to permeate the Blood-Brain Barrier (BBB) and shows no inhibitory activity against major CYP450 enzymes (CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4) or P-glycoprotein, minimizing potential drug-drug interactions. The absence of PAINS and Brenk alerts signifies a clean chemical profile regarding assay interference and toxicity flags. Although some stricter druglikeness filters were violated due to its polar nature, amoxicillin's overall in silico profile, combined with its established clinical efficacy, highlights the complex interplay of physicochemical properties and biological transport mechanisms. This study reaffirms amoxicillin's favorable attributes from a computational perspective, serving as a valuable reference for understanding established antibiotics and guiding future antimicrobial design.
SOSIALISASI DAN DEMONSTRASI TENTANG KESEHATAN DIRI PADA ANAK-ANAK MELALUI VIDEO Mildawati, Ratna; Prasetyo Nugroho, Bandhi; Prasetyawan, Fendy
Jurnal LENTERA Vol. 4 No. 1 (2024): Jurnal LENTERA
Publisher : Stikes Yarsi Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/lentera.v4i1.341

Abstract

Health is the most important part of human life, physically and spiritually healthy. However, not all children have sufficient knowledge about personal health. Elementary school age is an ideal time to train children's motor skills, including personal health. The aim is to provide education about personal health, including washing hands with soap, cleaning body parts, food and drink restrictions that can keep teeth and mouth clean. The methods used are demonstrations, counseling, using animated video media to create two-way communication and make students active in participating in activities. In this service, an instrument is used in the form of a questionnaire to measure students' knowledge and skills. The results of the socialization and demonstration that have been carried out are an increase of 40% to 90% in the knowledge indicator and an increase in skills of 35% to 80% in the skills indicator, so that this activity can be concluded to be able to increase the knowledge and skills of grade 3 students at Dawuhan Kidul I Elementary School. Explain about your own health.
EDUKASI SWAMEDIKASI PENGGUNAAN OBAT ASAM URAT PADA PEMERIKSAAN KESEHATAN BERKALA Mildawati, Ratna; Prasetyo Nugroho, Bandhi; Prasetyawan, Fendy; Kristjono, Ary; Saristiana, Yuneka
Jurnal LENTERA Vol. 4 No. 2 (2024): Jurnal LENTERA
Publisher : Stikes Yarsi Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/lentera.v4i2.369

Abstract

Self-medication or self-medication is the use of drugs or self-soothing forms of behavior to treat a perceived or real illness. Most Indonesians practice self-medication or use drugs to cure diseases, including gout and cholesterol. Aim: To increase understanding of how to self-medicate using gout and cholesterol medication. The method used is lectures related to education through leaflets and PPTs, discussions and questions and answers. The results of the Self-Medication Education after the pretest and posttest were that of the 32 participants, 5 were in the good category, 10 were adequate and 17 were poor, to 28 were good and 4 were sufficient, so that in this activity it can be concluded that there is an understanding of the community to carry out self-medication for gout and the importance of carrying out regular examinations so that they can detect early if there is an increase in uric acid
Spesialisasi Profesi Apoteker Untuk Optimalisasi Pharmaceutical Care Dalam Pendidikan Apoteker Advanced Practice Prasetyawan, Fendy; Saristiana, Yuneka; Fadel, Muhammad Nurul; Besan, Ema Jayanti; Ardianto, Nanda; Zahra, Ilhawa
SEARCH: Science Education Research Journal Vol. 2 No. 2 (2024): April 2024
Publisher : IAIN Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47945/search.v2i2.1342

Abstract

Abstract Penelitian ini membahas pengembangan profesi apoteker di Indonesia menjadi Apoteker Spesialis dan Advanced Practice. Inisiatif ini dilaksanakan oleh Pengurus Pusat Ikatan Apoteker Indonesia (PP IAI), Kolegium Ilmu Farmasi Indonesia (KIFI), dan perguruan tinggi, dengan mengacu pada model pengembangan yang dirumuskan oleh International Pharmaceutical Federation (FIP). Proses ini mengadopsi dan mengadaptasi standar internasional untuk disesuaikan dengan kebutuhan dan kondisi lokal di Indonesia. Melalui pendekatan "adopt and adapt," mekanisme Rekognisi Pembelajaran Lampau (RPL) diintegrasikan dalam sistem registrasi online yang diperkenalkan oleh KIFI, mempermudah proses pendaftaran dan administrasi program pengembangan profesi. Penyesuaian kurikulum, metode pengajaran, dan sistem evaluasi dilakukan untuk menjamin relevansi dan kualitas pendidikan yang diberikan. Pengakuan internasional terhadap kompetensi apoteker Indonesia tidak hanya meningkatkan daya saing tenaga kerja tetapi juga membuka peluang kolaborasi internasional dan peningkatan kualitas layanan kesehatan. Inisiatif ini berdampak signifikan pada sistem kesehatan nasional dengan meningkatkan kompetensi apoteker dalam berbagai peminatan spesialis, termasuk farmasi nuklir, farmasi interna, farmasi neonatus dan anak, farmasi intensif, dan farmasi onkologi. KIFI bekerja sama dengan berbagai pihak untuk memastikan bahwa program pendidikan dan sertifikasi yang diselenggarakan memenuhi standar nasional dan internasional. Pengembangan ini menunjukkan komitmen Indonesia untuk meningkatkan kualitas pendidikan dan praktik farmasi, memastikan apoteker siap menghadapi tantangan kesehatan masa depan, dan memperkuat posisi Indonesia di kancah internasional. Dengan kolaborasi yang erat antara semua pemangku kepentingan, Indonesia dapat mencetak apoteker yang kompeten, profesional, dan siap berkontribusi pada peningkatan kualitas hidup masyarakat serta penguatan sistem kesehatan nasional.
Sosialisasi Penyakit Populer dikalangan muda-mudi melalui Penerapan Pola Hidup Sehat Ratna Mildawati; Ary Kristijono; Fendy Prasetyawan; Yuneka Saristiana; Bandhi Prasetya Nugroho
Jurnal Pengabdian Kepada Masyarakat Al-Amin Vol. 2 No. 1 (2024): January 2024
Publisher : STAI Al-Amin Gersik Kediri Lombok Barat-NTB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54723/jpa.v2i1.136

Abstract

Joint disease is a non-communicable disease that is often experienced by teenagers and middle-aged people. This disease is mostly suffered by the age group over 15 years which causes various complications. The aim of this program is to increase public knowledge, especially teenagers and middle-aged people, and understanding of gout and cholesterol, especially regarding how to prevent it, so that it can help improve the quality of public health. The method of this activity is carried out by means of online and offline education and socialization which is carried out in three stages. The first stage is preparation of activities, the second stage is implementation of activities, and the third stage is implementation of evaluation activities and preparation of reports. The implementation of this activity includes the stages of providing material, question and answer and ending with a posttest. The results after being given the material and the posttest showed an increase in knowledge and understanding about popular diseases according to the posttest score. It is hoped that this socialization will be able to prevent popular diseases that most young people experience, so that it can improve the quality of public health.
Strategi Pencegahan COVID-19: Peningkatan Imunitas Tubuh Melalui Edukasi Konsumsi Teh Kombucha Akhmal, Faisal; Fendy Prasetyawan; Yuneka Saristiana; Ratna Mildawati; Anis Akhwan Dhafin
Jurnal Pengabdian Kepada Masyarakat Al-Amin Vol. 2 No. 1 (2024): January 2024
Publisher : STAI Al-Amin Gersik Kediri Lombok Barat-NTB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54723/jpa.v2i1.138

Abstract

The COVID-19 pandemic, triggered by the coronavirus 2 (SARS-CoV-2), demands a rapid and effective response to protect the global community. This article discusses prevention strategies with a focus on boosting the body's immunity through education and the consumption of kombucha tea. COVID-19 varies in symptoms and impacts, requiring a holistic approach. Kombucha tea, a result of fermenting sweet tea with a SCOBY, provides high nutrition and health benefits, particularly in strengthening the immune system. Community outreach activities are conducted to disseminate information to healthcare professionals and students, discussing the benefits of kombucha tea in enhancing immunity during the pandemic. The methods of these activities involve preparation, implementation of educational sessions, and participant satisfaction evaluations. Research findings highlight the potential of kombucha tea, especially its antioxidant and anti-inflammatory compounds, in enhancing the body's resilience against SARS-CoV-2. This strategy can be reinforced by emphasizing overall healthy lifestyles. Despite its promise, challenges in implementation require effective education and cross-sector collaboration. The conclusion emphasizes the importance of a holistic approach and education in building the foundation of public health amid the pandemic.
Improvement Strategy for Procurement Using the Hanlon Method at the Public Health Centers in Kediri Prasetyawan, Fendy; Widodo, Gunawan Pamudji; Purwidyaningrum, Ika
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7254

Abstract

Public Health Center (PHC) was a health center that needed and demanded by the community, accordingly availability and quality of medicines at PHC should met the needs. Purpose of this study were to determine the level of conformity and specify selection and procurement strategies for pharmaceutical service standards in Kediri's PHC based on priority scale of problem using Hanlon analysis. Design of this study was a non-experimental study, with data were analyzed quantitative and qualitative, collected using questionnaire instrument by conducting interviews, while results of this study was data in the form of counting results from respondent’s answers. The research results indicate that the procurement compliance level at the Public Health Centers in Kediri City has one problematic indicator, namely the percentage of procurement compliance with the actual usage for each drug item. Meanwhile, three indicators that are in compliance include the frequency of procurement for each drug item, the frequency of invoice errors, and the frequency of delayed payments by Puskesmas in relation to the established timelines.
Identification Of Escherichia Coli Bacterial Contamination in Home Industry Baby Porridge In The Malang City Area Dafin, Anis Akhwan; Putri, Elsa Mahardika; Prasetyawan, Fendy; Muslikh, Faisal Akhmal; Ma’arif, Burhan; Megawati, Dewi Sinta
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7269

Abstract

Growth and development in toddlers is very important, especially the nutritional needs of toddlers. MP-ASI is additional food to provide sufficient nutrition for babies. MP-ASI is divided into two types, namely traditional and industrial. Traditional MP-ASI is baby porridge that is prepared by yourself and sold on the side of the road. Hygiene and sanitation in roadside food can have a negative impact on consumers, especially bacterial contamination of food, one of which is Coliform bacteria, Escherichia Coli, etc. The method for calculating and estimating the number of E. coli bacteria found in chicken meat in this study used the Most Probable Number (MPN). The results showed that of the 4 samples tested, 3 were contaminated with E. Coli bacteria and 1 was negative for E. Coli bacterial contamination
ADMET Prediction of the Dominant Compound from Mangosteen (Garcinia mangostana L.) using pkCSM: A Computational Approach Muslikh, Faisal Akhmal; Kurniawati, Evi; Ma'arif, Burhan; Zenmas, Syendriva Zeptyan; Salmasfattah, Novyananda; Dhafin, Anis Akhwan; Prasetyawan, Fendy
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7271

Abstract

Mangosteen (Garcinia mangostana L.) is a plant belonging to the Guttiferae family with origins in Southeast Asia. The primary components in mangosteen peel consist of xanthones, particularly α-mangostin, which displays diverse pharmacological effects such as anti-diabetic properties, antioxidant activity, and anti-inflammatory effects. However, due to the insufficient information regarding studies on pharmacokinetics (administration, distribution, metabolism, excretion, and toxicity), the objective of this investigation is to explore pharmacokinetic predictions utilizing the pkCSM web tool. The α-mangostin compound, acquired from PubChem accessible at https://pubchem.ncbi.nlm.nih.gov/, underwent pharmacokinetic analysis using the web tool available at https://biosig.lab.uq.edu.au/pkcsm/prediction. The study findings revealed that the α-mangostin compound, subjected to pharmacokinetic analysis with pkCSM, exhibited limited distribution capability.
Co-Authors Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Akhmal, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Alves, Silvina Sandra X. Amanda, Cornelia Ana Amalia Anak Agung Indah Krisnadewi Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Apriliyani, Fitria Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arista Wahyu Ningsih Arsiaty Sumule Ary Kristijono Asrizal Azis Astutik, Widhi Ayu Angger Putri M. Soleh Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Charliandri Saputra Wahab Dafin, Anis Akhwan Dahbul, Nura Ali Dameria, Gempita Hutami Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Dyah Aryantini, Dyah Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Dhafin Elsa Mahardika Putri Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Emma Jayanti Besan Erawati, Dyah Anisa Indri Evi Kurniawati, Evi Evi Nurul Hidayati Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fita Sari Fita Sari, Fita Fitrani Khansa Fitriani, Evi Tunjung Freitas, Maria Do Carmo Da Costa Gunawan Pamudji Widodo Hakim, Adiyansyah Lukman Hamzah, Hasyrul Hasriyani Hasriyani Hasriyani, Hasriyani Herman Hilmi, Mochammad Hanif Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ika Purwidyaningrum Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Iramadona, Putri Ayu Isma Oktadiana Ivan Junius Mesak Juan Vega Mahardhika Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Khumaeni, Eko Hidayaturrohman Koernia, Lilik Wahidah Kristjono, Ary Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan Ma'arif, Burhan Maharani Dwi Pratiwi Marhenta, Yogi Bhakti maswan daulay Ma’arif, Burhan Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Muslikh, Faisal Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Okky Intan Mawarni Okky Intan Mawarni okta, isma Oktadiana, Isma Permata, Agung Prasetyo Nugroho, Bandhi Prayoga Fery Yuniarto Prayogi, Syaiful Purnomo Puspitosari, Dewi Retno Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Ratno Setyobudi Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Rosa Juwita Hesturini Sado, Yosep Mansen Salim Efendy Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Setyawan, Ferdinta Daniasta Shinta Mayasari Shinta Mayasari Shutiawan, Muhammad Alviyan Siti Nur Maulita Sugeng Rianto Sugeng Santoso Susilo Margining Raharjo Syntia Tanu Juwita Tri Wulan, Ema Tsamrotul Ilmi Wahab, Charliandari Saputra Widhi Astutik Widiyastuti, Asih Winartiana Winartiana, Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yosep Mosse Yuneka Sarisitiana Yuneka Saristiana Yuniarto, Prayoga Feri Yunita Dian Permatasari Zahra, Ilhawa Zenmas, Syendriva Zeptyan