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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran Syiah Kuala Jurnal Anestesi Perioperatif Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Damianus Journal of Medicine Mutiara Medika: Jurnal Kedokteran dan Kesehatan Majalah Obstetri dan Ginekologi Majalah Kedokteran Sriwijaya Jurnal Keperawatan Sriwijaya Biomedical Journal of Indonesia Paediatrica Indonesiana JURNAL KESEHATAN LINGKUNGAN: Jurnal dan Aplikasi Teknik Kesehatan Lingkungan Syntax Literate: Jurnal Ilmiah Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan IJEMS (Indonesian Journal of Environmental Management and Sustainability) Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) SRIWIJAYA JOURNAL OF MEDICINE Jurnal Biomedika dan Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ners Jurnal Aisyah : Jurnal Ilmu Kesehatan Sriwijaya Journal of Surgery Jurnal Integrasi Kesehatan dan Sains Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Majalah Kesehatan Indonesia Cendekia Medika : Jurnal Stikes Al-Ma`arif Baturaja CRJIM (Clinical and Research Journal in Internal Medicine) Journal of Community Development Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Kesehatan Gigi dan Mulut (JKGM) PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Journal of Anesthesiology and Clinical Research Lentera Perawat Majalah Anestesia & Critical Care (MACC) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Neurona Multidisciplinary Indonesian Center Journal Stetoskop : The Journal Of Health Science Journal of Multidisciplinary Academic and Practice Studies Poltekita: Jurnal Pengabdian Masyarakat Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Legiran Legiran
Department Of Biomedical Science, Medical Faculty Of Sriwijaya Universiy, South Sumatera, Indonesia
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PHYSICAL ENVIRONMENTAL INFLUENCES ON SILICOSIS: A NARRATIVE REVIEW INTEGRATING COMMUNITY EXPOSURE AND WISTAR RAT EXPERIMENTAL FINDINGS IN COAL-HANDLING REGIONS Mustika Fatimah; Irsan Saleh; Susila Arita; Legiran
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1808

Abstract

Coal mining, handling, and transportation activities are major sources of airborne particulate matter containing respirable crystalline silica, which poses significant risks to respiratory health. Silicosis remains a serious occupational and environmental disease affecting not only workers but also communities living near coal-handling areas. Physical environmental factors, including air quality, temperature, humidity, and wind speed, play an important role in influencing dust generation, dispersion, and inhalation exposure. This narrative review aims to synthesize current evidence on the influence of physical environmental conditions on silica exposure and silicosis development, integrating findings from environmental monitoring studies, epidemiological research, and experimental Wistar rat models. A literature search was conducted using major scientific databases to identify relevant peer-reviewed articles published between 2010 and 2024. The reviewed evidence indicates that prolonged or high-intensity exposure to silica dust is strongly associated with chronic pulmonary inflammation and progressive fibrosis. Environmental conditions can exacerbate exposure risk by increasing airborne particulate concentrations and respiratory vulnerability. Experimental studies using Wistar rats provide mechanistic insights into silica-induced lung injury, supporting epidemiological observations in human populations. This review highlights the importance of integrating environmental, occupational, and biological perspectives to improve risk prediction, early detection, and preventive strategies for silicosis in coal-handling regions.
Analysis of compliance with Antiretroviral (ARV) drinking of HIV patients in Regional General Hospitals Central Bangka District Kurrohman, Taufik; Sunarsih, Elvi; Sitorus, Rico Januar; Legiran, Legiran; Yunindyawati, Yunindyawati
Journal of Multidisciplinary Academic and Practice Studies Vol. 2 No. 4 (2024): November
Publisher : Goodwood Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jomaps.v2i4.2157

Abstract

Purpose: This study aimed to analyze the knowledge, attitudes, and compliance with antiretroviral (ARV) antidotes among HIV patients at the Central Bangka Regional General Hospital. Research Methodology: This study used a qualitative method with a phenomenological approach. The technique for selecting respondents was a non-probability sampling technique, purposive sampling. Nine informants participated in 9 people. Data were collected using an in-depth interview guide. Results: Findings from the research show that several informants had insufficient knowledge about compliance in taking ARV antidotes. Even though the informants' attitude towards compliance with antiretroviral (ARV) antiretrovirals was relatively good, several key informants stated that they had stopped taking antiretroviral (ARV) antidotes for several months because they felt healthy. However, several months later, they experienced adverse effects that resulted in declining health. Conclusions: The study concludes that Inadequate knowledge and misconceptions about ARV therapy remain significant obstacles to sustained adherence. Strengthening education, family involvement, and consistent supervision are essential for enhancing compliance and improving health outcomes for people living with HIV. Limitations: The study was limited to a small number of participants from a single hospital, which restricts broader generalization. Contribution: This research provides practical insights for healthcare providers and policymakers to design targeted interventions, improve supervision, and foster cross-program collaboration to ensure consistent ARV adherence among patients with HIV, ultimately supporting public health goals in HIV management.
Korelasi Kadar Serum Albumin terhadap Massa, Kekuatan Otot dan Performa Fisik pada Usia Lanjut di Poliklinik Geriatri Rsmh Palembang Riviati, Nur; Legiran; Saleh, Irsan; Indrajaya, Taufik; Dharma, Surya; Reagen, Muhammad; Yuniarti, Fifi; Rasidi, Syafran; Lubis, Fadhyl Zuhry; Indra, Bima
Bahasa Indonesia Vol 22 No 1 (2023): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v22i1.4233

Abstract

Introduction: Sarcopenia is a common problem found in the elderly. It is characterized by loss of muscle mass, muscle strength, and/or low physical performance. Currently, there’s little research on the association between serum albumin and muscle mass, muscle strength, and physical performance in the elderly, especially in Indonesia. This study aimed to find the correlation between serum albumin and muscle mass, muscle strength, and physical performance in the elderly. Method: A cross-sectional study was conducted from July 2022 to December 2022 towards elderly patients (>60 years) from the geriatric polyclinic at RSUP Moh. Hoesin Palembang. Serum albumin was examined for its correlation with muscle mass, muscle strength, and physical performance using Spearman’s test. Result: 41 elderly patients were included in this study (mean age 70.75 ± 7 years, 56.1% women). Correlation analysis showed that there’s a significant positive correlation between serum albumin with muscle strength (r=0.354, p=0.012) and a negative correlation with physical performance (r=-0.5, p <0.001). In comparison, there was no significant correlation between serum albumin and muscle mass (r=- 0.05, p=0.367). Conclusion: Muscle strength and physical performance have a significant correlation with serum albumin in the elderly. Therefore, even in the normal range, lower serum albumin is closely related to sarcopenia in the elderly. Key Words: albumin, muscle mass, muscle strength, physical performance, sarcopenia.
Hubungan Morfologi Oosit dengan Angka Fertilisasi dan Kualitas Embryo Pada Program Fertilisasi In VitrO Angella, Gita; Legiran, Legiran; Effendi, Yusuf
Jurnal Ners Vol. 10 No. 2 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.56144

Abstract

Infertilitas masih menjadi masalah kesehatan reproduksi yang signifikan, dan keberhasilan program in vitro fertilization (IVF) dipengaruhi oleh kualitas gamet, khususnya morfologi oosit. Penelitian ini bertujuan menganalisis hubungan morfologi oosit dengan angka fertilisasi serta kualitas embrio pada tahap pembelahan hari ke-3 dan blastokista hari ke-5. Penelitian ini merupakan penelitian analitik observasional dengan desain analitik komparatif menggunakan data sekunder pasien IVF di Blastula IVF Center Siloam Sriwijaya Palembang periode Maret 2021–Desember 2024. Sampel terdiri dari 213 pasien yang dipilih dengan teknik consecutive sampling. Variabel bebas meliputi parameter morfologi oosit (sitoplasma, polar bodi, ruang perivitelline , zona pelusida, dan bentuk oosit), sedangkan variabel terikat adalah angka fertilisasi dan kualitas embrio. Analisis data dilakukan menggunakan uji Chi-Square. Hasil penelitian menunjukkan bahwa morfologi dengan ruang perivitelline dan zona pelusida berhubungan signifikan dengan angka fertilisasi (p < 0,05). Pada kualitas embrio hari ke-3, ruang perivitelline dan bentuk oosit menunjukkan hubungan bermakna, sedangkan pada tahap blastokista hari ke-5 tidak ditemukan hubungan signifikan antara morfologi oosit dan kualitas embrio. Kesimpulannya, pengaruh morfologi oosit lebih dominan pada tahap awal perkembangan embrio dibandingkan tahap blastokista.
Co-Authors Abdul, Zabidah Achmad Ridwan, Achmad Ade Dian Anggraini Ade Permana Adinda Adinda Adinda Adnindya, Msy Rulan Afriani Ahmat Umar Alibasyah A. Chakra Andrina, Hana Angella, Gita Ansyori Hatta Ariani Susanti Arwan Bin Laeto Asri Maharani Astuti, Syurmi Aswin Nugraha Ayeshah A Rosdah Baehaqi Bella Ria Astuti Benny Kusuma Bermansyah Bernhard Arianto Purba Bunga Anggreini Sari Chandra, Novy Rosalia Christin, Theresia Danny Amos Tarigan Desi Arlindia Dian Wahyuni Diana Dewi Sartika, Diana Dewi Diana Polania Dini Rizkie Wijayanti Dini Rizkie Wijayanti Dwi Ariska Eddy Mart Salim Eddy Mart Salim, Eddy Mart Edi Susanto Effendi, Kms. Yusuf Efman EU Manawan Efrieni Yusuf Eka Febri Zulissetiana Elvi Sunarsih Erial Bahar Febrianto, Yohanes Ferawaty Ferawaty, Ferawaty Ferry Yusrizal Fitri Nurjanah Fitri Nurjanah Fitriani Fitriani Fredi Heru Irwanto Fredy Ferdinand Carol Furqan Indah Gama Satria Gama Satria Ghanie Abla Hafid Komar Handayani, Sri Harun, Yusril Hasbi, Alfian Henry Sugiharto Indah, Furqan INDRA FRANA JAYA KK Indra, Bima Indrajaya, Taufik Indri Seta Septadina Irfannuddin Irfannuddin Irsan Saleh Irsan Saleh, Muhammad Islamia, Medina Putri Jayawarsa, A.A. Ketut Joneri, Alrahman KAMILA, YURI Kartika, Juspeni Kemas Muhammad Dahlan Kesty, Cindy Kgs. M. Rosyidi Kms Yusuf Effendi Kms. Yusuf Effendi Kurniawan, Didy Layal, Kamalia Lubis, Fadhyl Zuhry M. Afif Heldian Putra M. Zalili Azis Mahardika Putri, Sima Asmara Dewa Marya Malahayati, Putri Martinova, Vera Mediarty Mega Sary Mega Sary Meirisa Rahma Pratiwi Mgs. Irsan Saleh Mgs.Muhammad Irsan Saleh Misnaniarti Misnaniarti Muhammad Arma Muhammad David Riandy Muhammad Hasnawi Haddani Muhammad Ikhsan Kartawinata Muhammad Irsan Saleh Muhammad Reagan MUSTIKA FATIMAH Mutiara Budi Azhar Nadia Maharni Nadya Aviodita Nedya Bellinawati Nopriyati Nova Kurniati Novy Rosalia Chandra Nur Qodir Nur Qodir Nur Riviati, Nur Nurjanah, Fitri Odiesta, Muhammad Ramadhan Okta Emilia Patiyus Agustiansyah Patresia, Retta Pirma I.R.M Precelia Fransiska Puspa Zuleika, Puspa Putri Mirani Qodir, Nur Radema Pranata Rasidi, Syafran Reagen, Muhammad Ria Nova Rico Januar Sitorus Ridho Surya Putra Rika Purnama Sari Rini Nindela, Rini Rizal Sanif Rizal Zainal Rizma Adlia Syakurah Rose Mafiana Safyudin Saleh, Muhammad Irsan Salni Salni Sari, Sagita Darma Sary, Mega Sepiwiryanti, Wika Shafira Irmayati Sima Asmara Dewa Marya Mahardika Putri Siti Nurmaini Siti R. Nanin Siti Rusdiana Puspa Dewi Soenarto Kartowigno Sugiharto, Henry Suly Auline Rusminan Surya Dharma Susila Arita Syifa Alkaf Taufik Indrajaya Taufik Kurrohman Theresia Christin Tri Suciati Tri Suciati Vidro Alif Gunawan Wahyuni, Devi Azri Wardiansah Wardiansah, Wardiansah Wiria Aryanta Yangtjik Yangtjik Yuli Kurniawati Yuniarti, Fifi Yunindyawati Yunindyawati Yuniza Yusni Puspita Yusuf Effendi Yusuf, Khaidir Zakaria Mukalla Zen Hafy Zulkhair Ali Zulkifli