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Journal : Medula

Carpal Tunnel Syndrome Pada Petani : Tinjauan Pustaka Azzahra, Herina; Utama, Winda Trijayanthi
Medula Vol 16 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i1.1755

Abstract

Carpal Tunnel Syndrome (CTS) is a compression neuropathy resulting from increased pressure on the median nerve within the carpal tunnel, characterized by pain, paresthesia, and numbness affecting the thumb to the third finger. CTS represents one of the most common musculoskeletal disorders, particularly among workers engaged in repetitive hand movements, forceful manual tasks, or prolonged non-ergonomic wrist postures. Globally, its prevalence varies across populations and may reach 7–20% among industrial workers. In Indonesia, CTS remains an underreported condition and is often regarded as an iceberg phenomenon due to limited clinical detection and reporting. CTS may be idiopathic or secondary to conditions such as pregnancy, obesity, hypothyroidism, and diabetes mellitus. Diagnosis is primarily clinical, supported by provocative tests such as Phalen’s test, Tinel’s sign, and the wrist extension test, as well as neurophysiological assessments including electromyography and nerve conduction studies. Radiological imaging may assist in excluding other structural causes. Management consists of conservative measures such as activity modification, wrist exercises, splinting, and the use of analgesics or anti-inflammatory agents. In moderate to severe cases, surgical decompression through division of the transverse carpal ligament is required to reduce pressure on the median nerve. Preventive strategies focus on improving workplace ergonomics, controlling comorbid conditions, and providing education regarding safe hand-use practices.
Perbandingan Absolute Lymphocyte Count (ALC) Antara Pasien Terkonfirmasi Dengan Probable Covid 19 Di RSUD Pesawaran Kurniawan, Denny Andika; Utama, Winda Trijayanthi
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1763

Abstract

Coronavirus Disease 2019 (COVID-19) is a broad group of viruses known to cause diseases with a diverse clinical spectrum, ranging from mild symptoms to severe disorders in humans. These viruses are zoonotic, meaning they can be transmitted from animals to humans, posing a major challenge in infection control efforts. In addition, variations in immune responses in each individual cause the clinical picture of Covid-19 to vary greatly, including changes in laboratory parameters such as absolute lymphocyte count (ALC). This study was conducted to analyze the differences in ALC values in patients with a confirmed diagnosis of Covid-19 compared to patients categorized as probable Covid-19 at the Pesawaran Regional General Hospital. The study design used an observational analytical method with a cross-sectional approach. Data processing and analysis were performed using an independent t-test to assess the difference in means between the two groups. The total sample consisted of 45 patients, namely 20 patients with confirmed Covid-19 and 25 patients with probable Covid-19. The results showed that the mean ALC value in the confirmed group was 1,241.5/µL, while in the probable group it reached 1,812.59/µL. These findings indicate a statistically significant difference between the mean ALC of the two groups, with a p-value of 0.0001. This difference also supports the findings of previous studies that lymphopenia is more commonly found in patients with verified Covid-19 infection. Thus, this study confirms that Covid-19 confirmation status is associated with changes in ALC, which can be a supporting clinical parameter in the evaluation and monitoring of patient conditions.
DRY EYE SYNDROME PADA PEKERJA KANTOR: TINJAUAN PUSTAKA Eltidar, Tyaradhia Ranita; Utama, Winda Trijayanthi
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1779

Abstract

An epidemiological study in the United States involving 75,000 adults reported that 5,051 individuals, or 6.73%, were diagnosed with Dry Eye Syndrome (DES), highlighting its growing importance as a public health issue, particularly among office workers with prolonged digital screen exposure. The extensive use of computers, smartphones, and tablets contributes to DES primarily through reduced blink frequency and incomplete blinking, which increase tear evaporation and lead to ocular surface dryness. Prolonged screen exposure may also induce oxidative stress and inflammation on the ocular surface, accelerating DES development. Workplace environmental factors, including air conditioning, artificial lighting, and low humidity, further elevate the risk, while blue light from screens may disrupt circadian rhythms, reduce tear production, and exacerbate symptoms. Poor ergonomic practices, such as improper screen positioning and prolonged near work, add visual strain and worsen Digital Eye Strain. A cross-sectional study in Bangladesh in 2023 found that daily screen time exceeding 8 hours, blink rates below 10 blinks per minute, and air-conditioned work environments significantly increased DES risk among office workers. Similar findings were reported in a 2024 cross-sectional study from India, which also identified screen distances of less than 50 cm and workplace humidity below 30% as risk factors. In addition, a cohort study in the Netherlands showed that professionals in legal, health, business, and administrative sectors had a higher risk of developing DES, which has been shown to reduce work productivity after symptom onset.
Perbedaan Tingkat Pengetahuan Tentang Diabetes Melitus Dengan Kadar Gula Darah Sewaktu Pasien DM Tipe 2 Saribu, Samintola Dolok; Utama, Winda Trijayanthi
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1806

Abstract

Diabetes mellitus (DM) is a degenerative disease characterized by elevated blood sugar levels or hyperglycemia. The incidence of DM continues to increase every year, influenced by various factors such as suboptimal recovery, the need for continuous consumption of antidiabetic drugs, uncontrolled blood sugar levels, and low patient knowledge about the disease. This condition can worsen complications and reduce the quality of life of patients. This study was conducted to determine the difference in the level of knowledge about diabetes mellitus with blood sugar levels in type 2 diabetes mellitus patients at Dr. H. Abdul Moeloek Regional General Hospital in Lampung Province. This study used a descriptive method with a cross-sectional study design. Sampling was conducted using non-probability sampling, specifically consecutive sampling, with instruments in the form of questionnaires to measure knowledge levels and random blood sugar level tests. Data were analyzed using the chi-square test to see the relationship between variables. A total of 35 respondents participated in this study, with 11.4% in the good knowledge category, 14.3% in the adequate category, and 74.3% in the poor category. The average blood sugar level of the respondents was 285 mg/dL. The statistical test results showed a p-value of 0.003, indicating a significant difference between the level of knowledge about diabetes mellitus and fasting blood sugar levels. Thus, this study concluded that the level of patient knowledge has a significant relationship with fasting blood sugar levels in type 2 DM patients.
Low Back Pain Pada Petani Karet: Sebuah Tinjauan Pustaka Pratama, Redi Bintang; Utomo, Muhammad Aditya; Utama, Winda Trijayanthi
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1818

Abstract

 Low Back Pain (LBP) is one of the most common musculoskeletal disorders experienced by agricultural workers, including rubber farmers, due to heavy physical demands, repetitive activities, and non-ergonomic work postures. The high prevalence of LBP among rubber farmers has the potential to reduce work productivity, increase the risk of disability, and negatively impact quality of life. This study aims to review the literature related to the incidence, prevalence, risk factors, and prevention and management efforts for Low Back Pain in rubber farmers. The method used is a literature review by searching for scientific articles through the Google Scholar, PubMed, ScienceDirect, and Garuda databases. The articles included were original studies in Indonesian and English published in the last ten years and discussed LBP in rubber farmers or agricultural workers with similar work characteristics. The results of the study showed that the prevalence of LBP among rubber farmers was relatively high, ranging from 33% to more than 70%. The main risk factors include heavy workloads, non-ergonomic work postures, repetitive work activities, prolonged standing or bending, and working without ergonomic training. Individual factors such as age, length of service, body mass index, and smoking habits also contribute to an increased risk of LBP. Recommended LBP prevention and management efforts include applying ergonomic principles at work, regulating work and rest times, occupational health education, stretching and back muscle strengthening exercises, and controlling individual risk factors. The conclusion of this literature review indicates that LBP among rubber farmers is a multifactorial occupational health problem that requires ergonomic interventions and continuous occupational health promotion.
Efektivitas Amoxicillin dan Piperacillin Terhadap Klebsiella pneumoniae pada Kasus Infeksi Saluran Pernapasan Akut di RSUD Dr. H. Abdul Moeloek Periode 2019 – 2023 Azalia, Nadhira; Soleha, Tri Umiana; Larasati, Ratri Mauluti; Utama, Winda Trijayanthi
Medula Vol 16 No 4 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i4.1846

Abstract

Acute respiratory tract infection (ARI) is one of the leading causes of morbidity that often requires antibiotic therapy, with Klebsiella pneumoniae being one of the most commonly found bacterial pathogens and known to have a high level of antibiotic resistance. Irrational use of antibiotics can accelerate the development of resistance, so the effectiveness of antibiotics needs to be evaluated periodically. Amoxicillin and piperacillin are commonly used antibiotics in the management of ARTI. This study aimed to evaluate the effectiveness of amoxicillin and piperacillin against Klebsiella pneumoniae in cases of ARTI at Dr. H. Abdul Moeloek General Hospital from 2019 to 2023. This study is an observational analytical study with a cross-sectional design using secondary data in the form of culture results and antibiotic sensitivity tests from patient medical records. The sampling technique used total sampling with a total of 106 Klebsiella pneumoniae isolates. Data analysis was performed using the Chi-Square test. The results showed that the resistance rate of Klebsiella pneumoniae to amoxicillin was 92.5% with a sensitivity of 7.5%. In contrast, piperacillin showed a higher sensitivity of 58.5% although resistance was still found at 41.5%. Statistical tests showed a significant relationship between the type of antibiotic and the level of bacterial sensitivity (p-value < 0.001). The conclusion of this study indicates that piperacillin is more effective than amoxicillin in the management of ARI caused by Klebsiella pneumoniae and can be considered in the selection of empirical antibiotic therapy.
Co-Authors Adinur, Bima Aditia, Arianda Alghani, Sulthan Rafi Amanah, Nur Suci Amelia, Maya Rizky Amir, Anzela Ananda, Amallia Andari, Michelle Safna Andini Pramesti Ningrum Andriani, Silvia Anggraini, Dian Isti Anisa Adelia Anisa Nuraisa Jausal Annisa Auliya Dien Safitrie Arifah Putri Desenia Asep Sukohar Asyifa, Takhfa Nur Ayu Tiara FItri Azalia, Nadhira Azelia Nusadewiarti Azhar, Hafidz Sirojudhin Azmi, Aulia Salma Azzahra, Herina Balqis, Gasela Zalianti Bawono, Aloysius Krishartadi Damar Bayu Anggileo Pramesona Daulay, Suryani Agustina Desta Bulan Cahyarani Dharmesti, Rizky Aleyda Dian Pratiwi Dian Puspita Larasati Dita Ayu Permata Dewi Dwita Oktaria Dyah Wulan Sumekar Rengganis Wardani Dyah Wulan Sumekar Rengganis Wardani Eltidar, Tyaradhia Ranita Eniwati Eniwati Evi Kurniawaty Fadhilah, Retno Suci Fadhillah, Paisal Fatharanni, Mentari Olivia Fathia, Nauriel Febriyan, Heironimus Billy Ferdian, Ruben Fitri Maharani Fitria Saftarina Hafizh, Ahmad Fauzan Haq, Rais Amaral Helmi Ismunandar Indika Poloriani Tunang Indriyani, Reni Intan Kusumaningtyas Intanri Kurniati Intanri Kurniati Iqbal Lambara Putra Irawati, Nur Ayu Virginia Istiqomah, Dinni Jovita, Hasna Laili Khairun Nisa Kurniawan, Denny Andika Kurniawaty, Evi Kusuma, Febriyani Dyah Larasati, Ratri Mauluti Lariza Serafina Tobroni M. Yogie Fadli Maharani, Ardila Putri Maharani, Calista Putri Maharani, Raihan Syifa Maharani, Shella Marcellia, Selvi Maya Ganda Ratna Mersiana, Putri Febi Muhammad Aditya, Muhammad Muhammad Maulana Muhartono Muhartono Mutiara Vira Antonia Nasser, Ghalib Abdul Ni Putu Swastini Novita Carolia Novita Carolia Nur Ayu Virginia Irawati Nurhardita, Fika Nuriah Nuriah Nurladira, Salsanisa Tisno Nurliwayka Qodri, Amari Oktadoni Saputra Oktafany, Oktafany Pamarta, Rachel Dwyana Poppy Monika Sari Pratama, Redi Bintang Pratiwi, Naisya Midary Mutia Prayogi, Norbertus Marcell Puspitasari, Ratna Dewi Putra, Ruchpy Cahya Putri Puspa Devi Putri, Asyifa Dinda Raehana, Nabila Salwa Raharjo, Shafana Azzahra Rasmi Zakiah Oktarlina Ratna Dewi PS Ratna Dewi Puspita Sari Ratu Nirmala Wahyunindita Reni Indriyani Reni Indriyani Reni Indriyani Reynhard Theodorus Xaverius Saragih Riandini, Sabrina Risti Graharti Rizal Effendi, R E Sahputra, Rahmat Tridhandy Salma Alya Ihsan Salsabila Alifiyah Setiawan Salsabila Dzakiyyah Zahra Salsabila Nurislami Sany Setiawan Saribu, Samintola Dolok Satria Adi Nugraha Septia Eva Lusina Septiani, Linda Setiorini, Anggi Shinta Nareswari, Shinta Silvia Andriani Sirait, Naomi Elfriede Situmorang, Cindy Miranda Sofyan Musabiq Wijaya Sofyan Musyabiq Wijaya Stevani Febeline Steven, Nixon Suarto, Sutarto Suharmanto Suharyani Suharyani Suryawinata, Arli Sutarto Sutarto Sutarto Sutarto Sutarto Sutarto Sutarto Sutyarso Sutyarso Syazili Mustofa Syifa Rahmi Fadhila TA Larasati Tasya Nadia Putri Tri Umiana Soleha Tri Umiana Soleha Utomo, Muhammad Aditya W, Sofyan Musyabiq Waluyo Rudiyanto Wardani, Nanda Fitri Widjaja, Jovan Zahra, Tsurayya Fathma